Herwig Baier


Affiliation: Max-Planck-Institute of Neurobiology
Country: Germany


  1. Helmbrecht T, Dal Maschio M, Donovan J, Koutsouli S, Baier H. Topography of a Visuomotor Transformation. Neuron. 2018;100:1429-1445.e4 pubmed publisher
    ..This topographic organization supports a tectum-generated space code sufficient to steer orienting movements. We conclude that specific labeled lines guide object-directed behavior in the larval zebrafish brain. ..
  2. Larsch J, Baier H. Biological Motion as an Innate Perceptual Mechanism Driving Social Affiliation. Curr Biol. 2018;28:3523-3532.e4 pubmed publisher
    ..Our results reveal individual-level, innate perceptual rules of engagement in mutual affiliation and provide experimental access to the neural mechanisms of social recognition. VIDEO ABSTRACT. ..
  3. Förster D, Kramer A, Baier H, Kubo F. Optogenetic precision toolkit to reveal form, function and connectivity of single neurons. Methods. 2018;150:42-48 pubmed publisher
    ..As these in vivo approaches are non-invasive, we envision useful applications for the study of neuronal structure, function and connectivity during development and behavior. ..
  4. Thiele T, Donovan J, Baier H. Descending control of swim posture by a midbrain nucleus in zebrafish. Neuron. 2014;83:679-91 pubmed publisher
    ..We conclude that activity in the nMLF provides postural control of tail orientation and thus steers the direction of swimming. Our studies provide an example of fine-grained modularity of descending motor control in vertebrates. ..
  5. Temizer I, Donovan J, Baier H, Semmelhack J. A Visual Pathway for Looming-Evoked Escape in Larval Zebrafish. Curr Biol. 2015;25:1823-34 pubmed publisher
    ..Our data indicate that a subset of RGC axons within the tectum responds selectively to features of looming stimuli and that this input is necessary for visually evoked escape. ..
  6. Barker A, Baier H. Sensorimotor decision making in the zebrafish tectum. Curr Biol. 2015;25:2804-2814 pubmed publisher
    ..We propose a model in which valence-based decisions arise, at a fundamental level, from competition between dedicated sensorimotor pathways in the tectum. ..
  7. Filosa A, Barker A, Dal Maschio M, Baier H. Feeding State Modulates Behavioral Choice and Processing of Prey Stimuli in the Zebrafish Tectum. Neuron. 2016;90:596-608 pubmed publisher
    ..Our study has revealed a neuroendocrine mechanism that modulates the perception of food and the willingness to take risks in foraging decisions. ..
  8. Dal Maschio M, Donovan J, Helmbrecht T, Baier H. Linking Neurons to Network Function and Behavior by Two-Photon Holographic Optogenetics and Volumetric Imaging. Neuron. 2017;94:774-789.e5 pubmed publisher
    ..Together, this toolkit enables linking behavior to circuit activity with unprecedented resolution. ..
  9. Förster D, Arnold Ammer I, Laurell E, Barker A, Fernandes A, Finger Baier K, et al. Genetic targeting and anatomical registration of neuronal populations in the zebrafish brain with a new set of BAC transgenic tools. Sci Rep. 2017;7:5230 pubmed publisher
    ..Taken together, our study offers new tools for functional studies of specific neural circuits in zebrafish. ..

More Information


  1. Förster D, Dal Maschio M, Laurell E, Baier H. An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits. Nat Commun. 2017;8:116 pubmed publisher
    ..Here the authors report a new genetic toolbox, 'Optobow', which enables simultaneous optogenetic activation of single neurons in zebrafish and measuring the activity of downstream neurons in the network. ..