Max-Planck-Institute for Infection Biology

Summary

Organization: Max-Planck-Institute for Infection Biology
Country: Germany

Top Publications

  1. doi Methods for investigation of osteoclastogenesis using mouse embryonic stem cells
    Motokazu Tsuneto
    Max Planck Institute for Infection Biology, Berlin, Germany
    Methods Mol Biol 690:239-53. 2011
  2. ncbi Ras-associated small GTPase 33A, a novel T cell factor, is down-regulated in patients with tuberculosis
    Marc Jacobsen
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Infect Dis 192:1211-8. 2005
  3. ncbi 100th anniversary of Robert Koch's Nobel Prize for the discovery of the tubercle bacillus
    Stefan H E Kaufmann
    Max Planck Institute for Infection Biology, Schumannstrasse 21 22, 10117 Berlin, Germany
    Trends Microbiol 13:469-75. 2005
  4. ncbi The pre-B-cell receptor: selector of fitting immunoglobulin heavy chains for the B-cell repertoire
    Fritz Melchers
    Max Planck Institute for Infection Biology, Campus Charite Mitte, Schumannstrasse 21 22, D 10117 Berlin, Germany
    Nat Rev Immunol 5:578-84. 2005
  5. ncbi Decontamination with vaporized hydrogen peroxide is effective against Mycobacterium tuberculosis
    A Kahnert
    Max Planck Institute for Infection Biology, Berlin, Germany
    Lett Appl Microbiol 40:448-52. 2005
  6. pmc CD46-independent binding of neisserial type IV pili and the major pilus adhesin, PilC, to human epithelial cells
    Marieluise Kirchner
    Max Planck Institute for Infection Biology Department of Molecular Biology, Schumannstrasse 21 22, 10117 Berlin, Germany
    Infect Immun 73:3072-82. 2005
  7. pmc New issues in tuberculosis
    S H E Kaufmann
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstr, 21 22, 10117 Berlin, Germany
    Ann Rheum Dis 63:ii50-ii56. 2004
  8. ncbi Protein identification and tracking in two-dimensional electrophoretic gels by minimal protein identifiers
    Jens Mattow
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    Proteomics 4:2927-41. 2004
  9. ncbi Immune response to postprimary tuberculosis in mice: Mycobacterium tuberculosis and Miycobacterium bovis bacille Calmette-Guérin induce equal protection
    Hans Joachim Mollenkopf
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Infect Dis 190:588-97. 2004
  10. ncbi In silico selection of functional RNA molecules
    Volker Patzel
    Max Planck Institute for Infection Biology, Campus Charite Mitte, Schumannstrasse 21 22, 10117 Berlin, Germany
    Curr Opin Drug Discov Devel 7:360-9. 2004

Research Grants

  1. APOPTOSIS IN SHIGELLA INFECTIONS
    Arturo Zychlinsky; Fiscal Year: 1999
  2. APOPTOSIS IN SHIGELLA INFECTIONS
    Arturo Zychlinsky; Fiscal Year: 2003

Detail Information

Publications62

  1. doi Methods for investigation of osteoclastogenesis using mouse embryonic stem cells
    Motokazu Tsuneto
    Max Planck Institute for Infection Biology, Berlin, Germany
    Methods Mol Biol 690:239-53. 2011
    ..Surprisingly, one of these induction methods produces osteoclasts, osteoblasts, and also endothelial cells in the same culture dish. Hence, it is likely that ESCs in culture mimic the in vivo development of osteoclasts...
  2. ncbi Ras-associated small GTPase 33A, a novel T cell factor, is down-regulated in patients with tuberculosis
    Marc Jacobsen
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Infect Dis 192:1211-8. 2005
    ..tuberculosis. Our findings identify Rab33A as a T cell regulatory molecule in TB and suggest its involvement in disease processes...
  3. ncbi 100th anniversary of Robert Koch's Nobel Prize for the discovery of the tubercle bacillus
    Stefan H E Kaufmann
    Max Planck Institute for Infection Biology, Schumannstrasse 21 22, 10117 Berlin, Germany
    Trends Microbiol 13:469-75. 2005
    ..Despite great efforts, however, Koch failed to conquer tuberculosis, which still causes enormous health problems worldwide 100 years after his Nobel award...
  4. ncbi The pre-B-cell receptor: selector of fitting immunoglobulin heavy chains for the B-cell repertoire
    Fritz Melchers
    Max Planck Institute for Infection Biology, Campus Charite Mitte, Schumannstrasse 21 22, D 10117 Berlin, Germany
    Nat Rev Immunol 5:578-84. 2005
    ....
  5. ncbi Decontamination with vaporized hydrogen peroxide is effective against Mycobacterium tuberculosis
    A Kahnert
    Max Planck Institute for Infection Biology, Berlin, Germany
    Lett Appl Microbiol 40:448-52. 2005
    ..To determine the efficacy of room fumigation with vaporized hydrogen peroxide (VHP) in decontamination of viable Mycobacterium tuberculosis...
  6. pmc CD46-independent binding of neisserial type IV pili and the major pilus adhesin, PilC, to human epithelial cells
    Marieluise Kirchner
    Max Planck Institute for Infection Biology Department of Molecular Biology, Schumannstrasse 21 22, 10117 Berlin, Germany
    Infect Immun 73:3072-82. 2005
    ..These data support the notion that pilus-mediated gonococcal infection of epithelial cells can occur in a CD46-independent manner, thus questioning the function of CD46 as an essential pilus receptor for pathogenic neisseriae...
  7. pmc New issues in tuberculosis
    S H E Kaufmann
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstr, 21 22, 10117 Berlin, Germany
    Ann Rheum Dis 63:ii50-ii56. 2004
    ..We have constructed a recombinant BCG vaccine which, compared with wild-type BCG, induces superior protection not only against laboratory strains but also against clinical isolates of M. tuberculosis...
  8. ncbi Protein identification and tracking in two-dimensional electrophoretic gels by minimal protein identifiers
    Jens Mattow
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    Proteomics 4:2927-41. 2004
    ..Furthermore, it is shown that the power of the MPI approach strongly depends on distinct factors, most notably on the complexity of the proteome analyzed and accuracy of the mass spectrometer used for peptide mass determination...
  9. ncbi Immune response to postprimary tuberculosis in mice: Mycobacterium tuberculosis and Miycobacterium bovis bacille Calmette-Guérin induce equal protection
    Hans Joachim Mollenkopf
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Infect Dis 190:588-97. 2004
    ....
  10. ncbi In silico selection of functional RNA molecules
    Volker Patzel
    Max Planck Institute for Infection Biology, Campus Charite Mitte, Schumannstrasse 21 22, 10117 Berlin, Germany
    Curr Opin Drug Discov Devel 7:360-9. 2004
    ..The success of these significant but costly processes depends upon intelligent functional RNA design and the development of high-throughput compatible in silico selection tools and filters...
  11. ncbi [Immunology of tuberculosis: impact on the development of novel vaccines]
    T Ulrichs
    Max Planck Institut für Infektionsbiologie, Berlin
    Internist (Berl) 44:1374-84. 2003
    ..A new vaccine should elicit a better immune response than the natural infection and reliably protect from TB disease, regardless if given prior or post infection with M. tuberculosis...
  12. ncbi Functionally active CD8alphabeta+ TCRgammadelta intestinal intraepithelial lymphocytes in athymic nu/nu mice
    Yoshiko Emoto
    Department of Immunology, Max Planck Institute for Infection Biology, Schumannstrasse 21 22, 10117 Berlin, Germany
    Int Immunol 16:111-7. 2004
    ..Our findings suggest that CD8alphabeta(+) TCRgammadelta cells can develop in the intestine independently of a functional thymus/thymic epithelial cells and that they perform biological functions in situ...
  13. ncbi Introduction: Forum in immunology on neutrophils
    Arturo Zychlinsky
    Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Campus Charite Mitte, Schumannstrasse 21 22, 10177 Berlin, Germany
    Microbes Infect 5:1289-91. 2003
  14. ncbi Glucose-regulated stress proteins and antibacterial immunity
    Ulrike K Rapp
    Max Planck Institute for Infection Biology, Schumannstrasse 21 22, 10117 Berlin, Germany
    Trends Microbiol 11:519-26. 2003
    ..We describe transcriptional regulation of ER-resident stress proteins, their involvement in the cellular response to infection and discuss their potential as vaccine candidates against infectious diseases...
  15. ncbi Recent findings in immunology give tuberculosis vaccines a new boost
    Stefan H E Kaufmann
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstrasse 21 22, 10117 Berlin, Germany
    Trends Immunol 26:660-7. 2005
    ..For clinical trials, biomarkers need to be defined with T cells alternating between lung and periphery as prime indicator cells...
  16. ncbi Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis
    Florian Winau
    Department of Immunology, Max Planck Institute for Infection Biology, Schumannstrasse 21 22, 10117 Berlin, Germany
    Immunity 24:105-17. 2006
    ..tuberculosis infection. Taken together, we propose the detour pathway to represent a genuine immunological mechanism mediating crosspriming of CD8 T cells in vivo and protection against tuberculosis...
  17. ncbi Proteins unique to intraphagosomally grown Mycobacterium tuberculosis
    Jens Mattow
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    Proteomics 6:2485-94. 2006
    ..The relevance of these proteins as factors enabling intracellular survival of M. tuberculosis is being discussed...
  18. doi Novel tuberculosis vaccines on the horizon
    Shreemanta K Parida
    Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany
    Curr Opin Immunol 22:374-84. 2010
    ..The live mutants of Mycobacterium tuberculosis show great promise, but face a myriad of regulatory challenges...
  19. doi Novel tuberculosis vaccination strategies based on understanding the immune response
    S H E Kaufmann
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Intern Med 267:337-53. 2010
    ..Ultimately, vaccination strategies that achieve sterile eradication of, or prevent infection with, tubercle bacilli would be an ambitious highly promising goal...
  20. doi Cloning and expression of murine Ig genes from single B cells
    Thomas Tiller
    Max Planck Institute for Infection Biology, Chariteplatz 1, Berlin D 10117, Germany
    J Immunol Methods 350:183-93. 2009
    ....
  21. doi A rough guide to the non-coding RNA world of Salmonella
    Jörg Vogel
    RNA Biology Group, Max Planck Institute for Infection Biology, Chariteplatz 1, D 10117 Berlin, Germany
    Mol Microbiol 71:1-11. 2009
    ....
  22. doi Import of bacterial pathogenicity factors into mitochondria
    Vera Kozjak-Pavlovic
    Max Planck Institute for Infection Biology, Department of Molecular Biology, Research Group for Molecular Infection and Cancer Biology, Chariteplatz 1, Berlin, Germany
    Curr Opin Microbiol 11:9-14. 2008
    ..The review covers the current knowledge on the mitochondrial targeting and import of bacterial pathogenicity factors...
  23. ncbi An improved strategy for selective and efficient enrichment of integral plasma membrane proteins of mycobacteria
    Jens Mattow
    Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany
    Proteomics 7:1687-701. 2007
    ..The identified proteins were characterized with regard to biological functions and physicochemical properties providing further evidence for the high efficiency of the prefractionation method described herein...
  24. pmc Nitrogen fixation in eukaryotes--new models for symbiosis
    Christoph Kneip
    Department of Cell Biology, Philipps University Marburg, Marburg, Germany
    BMC Evol Biol 7:55. 2007
    ..Eukaryotic organisms are only able to obtain fixed nitrogen through their symbiotic interactions with nitrogen-fixing prokaryotes. These symbioses involve a variety of host organisms, including animals, plants, fungi and protists...
  25. ncbi Changing funding patterns in tuberculosis
    Stefan H E Kaufmann
    Max Planck Institute for Infection Biology, Department of Immunology, Chariteplatz 1, 10117 Berlin, Germany
    Nat Med 13:299-303. 2007
  26. ncbi RNA Silencing in the struggle against disease
    Volker Patzel
    Department of Immunology, Max Planck Institute for Infection Biology, D 10117 Berlin, Germany
    Ann N Y Acad Sci 1082:44-6. 2006
    ..We succeeded in triggering gene silencing by siRNA in prokaryotic cells. This opens promising perspectives regarding validation of prokaryotic gene functions...
  27. ncbi Small non-coding RNAs and the bacterial outer membrane
    Jörg Vogel
    Max Planck Institute for Infection Biology, RNA Biology Group, Chariteplatz 1, 10117 Berlin, Germany
    Curr Opin Microbiol 9:605-11. 2006
    ..An sRNA-OMP network is emerging in which some sRNAs act specifically on a single omp mRNA, whereas others control multiple omp mRNA targets...
  28. ncbi Exploiting immunology and molecular genetics for rational vaccine design against tuberculosis
    S H E Kaufmann
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    Int J Tuberc Lung Dis 10:1068-79. 2006
    ..The goal for the future would be to have these novel vaccine candidates tested in different combinations to facilitate the design of the most efficacious vaccination protocol...
  29. ncbi Envisioning future strategies for vaccination against tuberculosis
    Stefan H E Kaufmann
    Stefan H E Kaufmann is at the Max Planck Institute for Infection Biology, Department of Immunology, Schumannstrasse 21 22, 10117 Berlin, Germany
    Nat Rev Immunol 6:699-704. 2006
    ....
  30. ncbi Leprosy susceptibility-a matter of protein degradation? The role of proteasomes in infection and disease
    Ulrich Steinhoff
    Max Planck Institute of Infection Biology, Berlin, Germany
    Int J Lepr Other Mycobact Dis 73:135-7. 2005
  31. ncbi Towards simple artificial infectious systems
    Volker Patzel
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstrasse 21 22, D 10117 Berlin, Germany
    Trends Mol Med 9:479-82. 2003
    ..Artificial infectious systems can be useful for successive and penetrative tissue targeting...
  32. ncbi Highly biased type 1 immune responses in mice deficient in LFA-1 in Listeria monocytogenes infection are caused by elevated IL-12 production by granulocytes
    Masashi Emoto
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Immunol 171:3970-6. 2003
    ..In conclusion, LFA-1 regulates type 1 immune responses by controlling prompt infiltration of IL-12-producing granulocytes into sites of inflammation...
  33. ncbi Immune response to infection with Salmonella typhimurium in mice
    H W Mittrucker
    Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany
    J Leukoc Biol 67:457-63. 2000
    ..In summary, the response to S. typhimurium involves both T and B cell-mediated immunity, and mechanisms mediated by both lymphocyte populations are important for control of primary infection and protection against secondary infection...
  34. ncbi Strand switching during rolling circle replication of plasmid-like DNA circles in the mitochondria of the higher plant Chenopodium album (L.)
    S Backert
    Institut fur Biologie, Humboldt Universitat zu Berlin, Chausseestrasse 117, Berlin, D 10115, Germany
    Plasmid 43:166-70. 2000
    ....
  35. ncbi Cutting edge: role of B lymphocytes in protective immunity against Salmonella typhimurium infection
    H W Mittrucker
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Immunol 164:1648-52. 2000
    ..typhimurium involved both B cell-dependent and -independent effector mechanisms. Thus, B cell-mediated immunity plays a distinct role in control of S. typhimurium in susceptible mice...
  36. ncbi Activation of activator protein 1 and stress response kinases in epithelial cells colonized by Helicobacter pylori encoding the cag pathogenicity island
    M Naumann
    Max Planck Institut für Infektionsbiologie, Abteilung Molekulare Biologie, 10117 Berlin, Germany
    J Biol Chem 274:31655-62. 1999
    ..pylori encoding the cag pathogenicity island...
  37. ncbi Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells
    U Steinhoff
    Department of Immunology, Max Planck Institute of Infection Biology, Germany
    Immunity 11:349-58. 1999
    ..This report demonstrates that CD8 T cells with defined antigen specificity cause intestinal inflammation, emphasizing a link between infection and autoimmune disease...
  38. ncbi Caspase inhibitors in prevention of apoptosis
    T Rudel
    Max Planck Institut für Infektionsbiologie, Abteilung Molekulare Biologie, Berlin, Germany
    Herz 24:236-41. 1999
    ..This review will present the recent advances and discuss the potential of caspase inhibitors as future therapeutics...
  39. ncbi Cell-mediated immunity: dealing a direct blow to pathogens
    S H Kaufmann
    Max Planck Institute for Infection Biology, Berlin, Germany
    Curr Biol 9:R97-9. 1999
    ..Recent data demonstrating direct killing of intracellular bacteria by granulysin, a protein released from the granules of cytotoxic T lymphocytes, emphasize the contribution of these lymphocytes to the control of tuberculosis...
  40. pmc Soluble tumor necrosis factor alpha receptors in sera from leprosy patients
    M E Munk
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    Infect Immun 67:423-5. 1999
    ..This suggests that sTNF-R regulatory activities are partially impaired in patients with leprosy...
  41. ncbi In vitro replication of mitochondrial plasmid mp1 from the higher plant Chenopodium album (L.): a remnant of bacterial rolling circle and conjugative plasmids?
    S Backert
    Department of Botany and Microbiology, Auburn University, 101 Life Sciences Building, Auburn, AL, 36849, USA
    J Mol Biol 284:1005-15. 1998
    ..This sequence shares homology with double-stranded rolling circle origin (dso) or transfer origin (oriT) nicking motifs from bacterial plasmids. mp1 is the first described rolling circle plasmid in eukaryotes...
  42. ncbi Early IL-4 induction in bone marrow lymphoid precursor cells by mycobacterial lipoarabinomannan
    H L Collins
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Immunol 161:5546-54. 1998
    ..Thus, pathogenic mycobacteria and their glycolipids may influence hemopoiesis by rapidly inducing IL-4 secretion in the bone marrow...
  43. pmc Coordinate activation of activator protein 1 and inflammatory cytokines in response to Neisseria gonorrhoeae epithelial cell contact involves stress response kinases
    M Naumann
    Max Planck Institut für Infektionsbiologie, Abteilung Molekulare Biologie, 10117 Berlin, Germany
    J Exp Med 188:1277-86. 1998
    ..Our results indicate that Ngo induce the activation of proinflammatory cytokines via a cascade of cellular stress response kinases involving PAK, which directs the signal from the Rho family of small GTPases to JNK/AP-1 activation...
  44. ncbi [Immunologic foundations of new vaccination strategies]
    S H Kaufmann
    Abteilung fur Immunologie, Universitat Ulm, Germany
    Naturwissenschaften 85:62-72. 1998
    ..Such vaccines will not only contribute to control of infectious agents, but also allow novel strategies towards therapy of tumors, autoimmune disease and allergy...
  45. pmc Neisseria gonorrhoeae epithelial cell interaction leads to the activation of the transcription factors nuclear factor kappaB and activator protein 1 and the induction of inflammatory cytokines
    M Naumann
    Max Planck Institut für Infektionsbiologie, Abteilung Molekulare Biologie, 10117 Berlin
    J Exp Med 186:247-58. 1997
    ..Activation of NF-kappaB and cytokine mRNA upregulation also occur in Ngo-infected epithelial cells that were treated with cytochalasin D, indicating an extracellular signaling induced before invasion...
  46. ncbi Nuclear factor-kappa B activation and innate immune response in microbial pathogen infection
    M Naumann
    Department of Molecular Biology, Max Planck Institute for Infection Biology, 10117 Berlin, Germany
    Biochem Pharmacol 60:1109-14. 2000
    ....
  47. pmc Immunity against Helicobacter pylori: significance of interleukin-4 receptor alpha chain status and gender of infected mice
    T Aebischer
    Department of Molecular Biology, Max Planck Institute for Infection Biology, 10117 Berlin, Germany
    Infect Immun 69:556-8. 2001
    ..A comparison of male and female mice suggests a sexual dimorphism in the extent of bacterial colonization that is particularly evident in the absence of the IL-4Ralpha chain...
  48. ncbi Immune responses to intracellular bacteria
    B Raupach
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstrasse 21 22, 10117, Berlin, Germany
    Curr Opin Immunol 13:417-28. 2001
    ....
  49. ncbi Are NKT cells essential for endotoxic shock?
    Masashi Emoto
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    Arch Immunol Ther Exp (Warsz) 51:231-6. 2003
    ..It remains, however, elusive whether NK cells, NKT cells or both are involved in the induction of endotoxic shock. This review will focus on the relative contribution of these NK1+ cells to the pathogenesis of endotoxic shock...
  50. ncbi Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis
    Ulrich E Schaible
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstrasse 21 22, D 10117 Berlin, Germany
    Nat Med 9:1039-46. 2003
    ....
  51. ncbi Salmonella typhimurium strains carrying independent mutations display similar virulence phenotypes yet are controlled by distinct host defense mechanisms
    Barbel Raupach
    Department of Immunology, Max Planck Institut für Infektionsbiologie, Berlin, Germany
    J Immunol 170:6133-40. 2003
    ..However, for both mutants, ultimate clearance of bacteria from infected mice depended on alphabeta T cells...
  52. pmc Decline of North Atlantic eels: a fatal synergy?
    Thierry Wirth
    Québec Océan, Departement de Biologie, Universite Laval, Ste Foy, Quebec G1K 7P4, Canada
    Proc Biol Sci 270:681-8. 2003
    ....
  53. ncbi Promiscuous peptide recognition of an autoreactive CD8(+) T-cell clone is responsible for autoimmune intestinal pathology
    Immo Prinz
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstr 21 22, Campus Charite Mitte, D 10117 Berlin, Germany
    J Autoimmun 18:281-7. 2002
    ..Thus a single TCR is not only sufficient for crossrecognition with peptides that share minimal sequence homology, moreover this promiscuous TCR reactivity accounts also for immunopathology as recently shown...
  54. ncbi Critical role of NK cells rather than V alpha 14(+)NKT cells in lipopolysaccharide-induced lethal shock in mice
    Masashi Emoto
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Immunol 169:1426-32. 2002
    ..Hence, LPS-induced shock can be induced in the absence of V alpha 14(+)NKT cells and IFN-gamma from NK cells is involved in this mechanism. In WT mice, hierarchic contribution of different cell populations appears likely...
  55. pmc R-loop-dependent rolling-circle replication and a new model for DNA concatemer resolution by mitochondrial plasmid mp1
    Steffen Backert
    Department of Botany and Microbiology, Auburn University, Auburn, AL 36849, USA
    EMBO J 21:3128-36. 2002
    ..mp1 is a unique eukaryotic plasmid that expresses features of phages like T4 and could serve as a model system for replication and maintenance of DNA concatemers...
  56. ncbi The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis
    Jens Zerrahn
    Department of Immunology and Core Facility Microscopy, Max Planck Institute for Infectionbiology, Berlin, Germany
    J Immunol 168:3428-36. 2002
    ..We conclude that IIGP exerts a distinct role in IFN-induced intracellular membrane trafficking or processing...
  57. ncbi Mycobacterial persistence and immunity
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Schumannstrabe 21 22, 10117 Berlin, Germany
    Front Biosci 7:d458-69. 2002
    ..The following article reviews our knowledge about both pathogen and host mechanisms involved in the immune response to M. tuberculosis...
  58. ncbi Introduction: microbiology and immunology: lessons learned from Salmonella
    S H Kaufmann
    Department of Immunology, Max Planck Institute for Infection Biology, Schumannstr 21 22, 10117 Berlin, Germany
    Microbes Infect 3:1177-81. 2001
    ..enterica infections. This multidisciplinary research will enhance our understanding of the basic mechanisms of bacterial infections and immunity; it also provides new approaches towards therapeutic and control measures...
  59. pmc Characterization of the murine T-lymphocyte response to Salmonella enterica serovar Typhimurium infection
    Hans Willi Mittrücker
    Department of Immunology, Max Planck Institute for Infection Biology, 10117 Berlin, Germany
    Infect Immun 70:199-203. 2002
    ....
  60. ncbi Role of CD28 for the generation and expansion of antigen-specific CD8(+) T lymphocytes during infection with Listeria monocytogenes
    H W Mittrucker
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Immunol 167:5620-7. 2001
    ..However, Ag-specific CD8(+) T cells generated in the absence of CD28 differentiated into normal effector and memory T cells...
  61. ncbi Proteome analysis of bacterial pathogens
    P R Jungblut
    Max Planck Institute for Infection Biology, Support Unit for Biochemistry, Schumann Str 21 22, 10117, Berlin, Germany
    Microbes Infect 3:831-40. 2001
    ..Immunoproteomics identifies specific and nonspecific antigens. For the management of the huge data amounts, bioinformatics is a valuable instrument for the construction of complex protein databases...
  62. ncbi Low-molecular-weight protein ligands from Onchocerca volvulus preferentially stimulate the human gammadelta T cell Vdelta1+ subset
    M E Munk
    Department of Immunology, University of Ulm, Germany
    J Infect Dis 174:1309-15. 1996
    ..It is concluded that somatic 5- to 30-kDa protein ligands from O. volvulus stimulate Vdelta1+ T cells and that Vdelta1+ T cells play a role in immunity to O. volvulus...

Research Grants6

  1. APOPTOSIS IN SHIGELLA INFECTIONS
    Arturo Zychlinsky; Fiscal Year: 1999
    ..We will compare in animals experimentally infected with either wild type or non-pathogenic strains of S. flexneri, the induction of apoptosis in intestinal macrophages and other cell types. ..
  2. APOPTOSIS IN SHIGELLA INFECTIONS
    Arturo Zychlinsky; Fiscal Year: 2003
    ..abstract_text> ..