Research Topics
| Stefan MaussSummaryCountry: Germany Publications
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Detail Information
Publications
Cystatin C as a marker of renal function is affected by HIV replication leading to an underestimation of kidney function in HIV patientsStefan Mauss
Center for HIV and Hepatogastroenterology, Duesseldorf, Germany
Antivir Ther 13:1091-5. 2008..Broad use of tenofovir and an ageing HIV- infected population have created an interest in renal function in HIV patients. Serum cystatin C is a newer marker of renal function and might be more sensitive than creatinine...
Screening for autoantibodies in chronic hepatitis C patients has no effect on treatment initiation or outcomeS Mauss
Center for HIV and Hepatogastroenterology, Dusseldorf, Germany
J Viral Hepat 20:e72-7. 2013..Routine testing of these autoantibodies seems not warranted. Determination of autoantibodies should be guided by individualized clinical decisions...
Effect of HBV polymerase inhibitors on renal function in patients with chronic hepatitis BStefan Mauss
Center for HIV and Hepatogastroenterology, Duesseldorf, Germany
J Hepatol 55:1235-40. 2011..To assess renal function more accurately in the normal range, we used the recently validated, Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula to calculate the estimated glomerular filtration rate (eGFR)...
Estimating the likelihood of sustained virological response in chronic hepatitis C therapyS Mauss
Center for HIV and Hepatogastroenterology, Dusseldorf, Germany
J Viral Hepat 18:e81-90. 2011..In patients matched by baseline characteristics, treatment with peginterferon alfa-2a may be a positive predictor of SVR when compared to peginterferon alfa-2b...
Management and therapy of chronic hepatitis C virus infection in HIV-infected individualsStefan Mauss
Center for HIV and Hepatogastroenterology, Grafenberger Allee 128a, 40237 Duesseldorf, Germany
J HIV Ther 12:11-7. 2007....
Therapy of chronic hepatitis B: new goals and new treatmentsS Mauss
Center for HIV and Hepatogastroenterology, Grafenberger Allee 128a, 40237 Duesseldorf, Germany
Minerva Med 100:447-58. 2009..This review provides a strategy on how to manage HBV therapy with the currently available treatment options...
Treatment of chronic hepatitis B and the implications of viral resistance to therapyStefan Mauss
Center for HIV and Hepatogastroenterology, Grafenberger Allee 128a, 40237 Duesseldorf, Germany
Expert Rev Anti Infect Ther 6:191-9. 2008..Suggestions for avoiding resistance and management of established drug resistance are provided for each individual approved compound...
Lipoprotein(a) in patients initiating antiretroviral therapyS Mauss
Center for HIV and Hepatogastroenterology, Duesseldorf, Germany
HIV Med 9:415-20. 2008..In this study we assessed the effect of initiating antiretroviral therapy (ART) on lipoprotein(a) levels...
Combination of tenofovir and lamivudine versus tenofovir after lamivudine failure for therapy of hepatitis B in HIV-coinfectionGuenther Schmutz
Center for HIV and Hepatogastroenterology, Grafenberger Allee 128a, 40237 Duesseldorf, Germany
AIDS 20:1951-4. 2006..Over a median treatment period of 116 weeks tenofovir was as effective as tenofovir plus lamivudine. Longer treatment periods may be needed to evaluate potential benefits of first-line combination therapy for chronic hepatitis B...
Antiretroviral therapy with tenofovir is associated with mild renal dysfunctionStefan Mauss
Center for HIV and Hepatogastroenterology, Duesseldorf, Germany
AIDS 19:93-5. 2005..In total, 24 patients on tenofovir versus five control patients had proteinuria greater than 130 mg/day. In the majority of patients on tenofovir proteinuria was of tubular origin...
A prospective controlled study of interferon-based therapy of chronic hepatitis C in patients on methadone maintenanceStefan Mauss
Center for HIV and Hepatogastroenterology, Dusseldorf, Germany
Hepatology 40:120-4. 2004..Patients discontinuing therapy due to noncompliance or request did so early, thereby limiting the cost of an unsuccessful approach to treatment...
Risk factors for hepatic decompensation in patients with HIV/HCV coinfection and liver cirrhosis during interferon-based therapyStefan Mauss
Center for HIV and Hepatogastroenterology, , Germany
AIDS 18:F21-5. 2004..Treatment with antiretrovirals such as didanosine may increase the risk further...
Effects of HCV co-infection on apoptosis of CD4+ T-cells in HIV-positive patientsChristian Korner
Department of Internal Medicine I, University of Bonn, Germany, Sigmund Freud Str 25, Bonn 53127, Germany
Clin Sci (Lond) 116:861-70. 2009..The results of the present study suggest that HCV co-infection sensitizes CD4+ T-cells towards apoptosis in untreated HIV-positive patients. However, this effect is rapidly lost under effective antiretroviral therapy...
HIV-associated and antiretroviral-induced hyperlipidaemia: an updateStefan Mauss
Center for HIV and Hepatogastroenterology, Grafenberger Allee 128a, D-40237 Duesseldorf, Germany
J HIV Ther 8:29-31. 2003..Given the overall low number of cardiovascular events, an individualised approach seems adequate...
Differentiating hyperlipidaemia associated with antiretroviral therapyStefan Mauss
Center for HIV and Hepatogastroenterology, Duesseldorf, Germany
AIDS 17:189-94. 2003..Further research is needed to assess the contribution of VLDL-associated hypercholesterolaemia in those taking antiretroviral drugs to the cardiovascular risk profile of HIV-positive patients...
Treatment of viral hepatitis in HIV-coinfected patients-adverse events and their managementStefan Mauss
Center for HIV and Hepatogastroenterology, Grafenberger Allee 128a, 40237 Duesseldorf, Germany
J Hepatol 44:S114-8. 2006..Adverse events specific to the HCV/HIV-patient population as compared to HCV-mono-infected patients are the occurrence of hyperlactataemia/lactic acidosis and hepatic decompensation...
Clinical implications of resistance patterns against HBV-polymerase inhibitors for the treatment of chronic hepatitis BStefan Mauss
Center for HIV and Gastroenterology, , Germany
J HIV Ther 12:92-4. 2007
Care of HIV patients with chronic hepatitis B: updated recommendations from the HIV-Hepatitis B Virus International PanelVincent Soriano
Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain
AIDS 22:1399-410. 2008..The present study represents an update of the current knowledge about HBV/HIV coinfection and an intent to provide practical advise about how to give the best care to HIV-infected persons with chronic hepatitis B...
Care of patients coinfected with HIV and hepatitis C virus: 2007 updated recommendations from the HCV-HIV International PanelVincent Soriano
Department of Infectious Diseases, Hospital Carlos III, Calle Sinesio Delgado 10, 28029 Madrid, Spain
AIDS 21:1073-89. 2007
Pegylated interferon alpha-2b plus ribavirin for the treatment of chronic hepatitis C in HIV-coinfected patientsEsther Voigt
University of Bonn, Bonn, Germany
J Infect 53:36-42. 2006..Therefore, treatment options for chronic hepatitis C in HIV-coinfected patients need to be evaluated...
Care of patients with chronic hepatitis C and HIV co-infection: recommendations from the HIV-HCV International PanelVincent Soriano
AIDS 16:813-28. 2002
Pilot study of interferon alpha high-dose induction therapy in combination with ribavirin for chronic hepatitis C in HIV-co-infected patientsJürgen Kurt Rockstroh
Department of Medicine I, University of Bonn, Germany
AIDS 16:2083-5. 2002..In HIV/HCV-co-infected patients, the therapeutic benefit of high-dose IFN-alpha therefore seems to be limited by its poor tolerability...
Care of patients with hepatitis C and HIV co-infectionVincent Soriano
AIDS 18:1-12. 2004
Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infectionFlorian van Bömmel
Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Charite, Universitatsmedizin Berlin, Campus Virchow, Berlin, Germany
Hepatology 40:1421-5. 2004..In conclusion, tenofovir may become an effective alternative for the treatment of patients with lamivudine-resistant HBV infection...
Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovirJulie Sheldon
Hospital Carlos Ill, Madrid, Spain
Antivir Ther 10:727-34. 2005..In vitro, rtA194T conferred a reduced susceptibility to TDF in the presence of LAM-associated mutations...
Risk of selecting K65R in antiretroviral-naive HIV-infected individuals with chronic hepatitis B treated with adefovirJulie A Sheldon
Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain
AIDS 19:2036-8. 2005....
Low rate of treatment failure on antiretroviral therapy with tenofovir, lamivudine and zidovudineStefan Mauss
AIDS 19:101-2. 2005
Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or zalcitabineUlrich A Walker
Medizinische Universitatsklinik, Department of Clinical Immunology, Freiburg, Germany
Hepatology 39:311-7. 2004..Moderate mtDNA depletion in liver does not necessarily lead to hyperlactatemia, but more pronounced decreases in hepatic mtDNA may be an important contributor to lactate elevation...
Rapid development of central adiposity after postexposure prophylaxis with antiretroviral drugs: a proof of principle?Stefan Mauss
AIDS 17:944-5. 2003
Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patientsChristoph Wyen
Department of Internal Medicine, University of Cologne, Koln, Germany
J Antimicrob Chemother 61:914-8. 2008..The aim of this study was to investigate the frequency of CYP2B6 polymorphisms (according to ethnicity) and the influence of heterozygosity and homozygosity on plasma concentrations of efavirenz and nevirapine...
Unfavourable interaction of amprenavir and lopinavir in combination with ritonavir?Stefan Mauss
AIDS 16:296-7. 2002
