Research Topics
| K MathiakSummaryCountry: Germany Publications
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Publications
Mismatch responses to randomized gradient switching noise as reflected by fMRI and whole-head magnetoencephalographyKlaus Mathiak
Department of Neuroradiology, University of Tubingen, Germany
Hum Brain Mapp 16:190-5. 2002..The presented paradigm provides a robust and feasible tool to study the functional anatomy of early cognitive auditory processing in clinical populations such as schizophrenia...
The influence of critical bands on neuromagnetic fields evoked by speech stimuli in humansKlaus Mathiak
Department of Neurology, Universitat Tubingen, Otfried Müller Strasse 47, 72076 Tubingen, Germany
Neurosci Lett 329:29-32. 2002..The differences of early neuronal encoding of both formants relate to the predominant role of F2 for the encoding of stop consonants...
The right supratemporal plane hears the distance of objects: neuromagnetic correlates of virtual realityKlaus Mathiak
Department of Neurology, Universitat Tubingen, Otfried Müller Str 47, D 72076 Tubingen, Germany
Neuroreport 14:307-11. 2003....
Discrimination of temporal information at the cerebellum: functional magnetic resonance imaging of nonverbal auditory memoryKlaus Mathiak
Department of Neurology, University of Tubingen, D 72076, Tubingen, Germany
Neuroimage 21:154-62. 2004..This network allows for temporal organization of verbal sequences and phoneme encoding based on durational operations in a linguistic context...
Cerebellum and speech perception: a functional magnetic resonance imaging studyKlaus Mathiak
MEG Zentrum, University of Tubingen, Otfried Müller Strasse 47, 72076 Tubingen, Germany
J Cogn Neurosci 14:902-12. 2002..Conceivably, representation of the temporal structure of speech sound sequences represents the common denominator of cerebellar participation in cognitive tasks acting on a phonetic code...
Evaluation of motion and realignment for functional magnetic resonance imaging in real timeK Mathiak
Research Center Julich, Institute of Medicine, Julich, Germany
Magn Reson Med 45:167-71. 2001..As the estimation of large movements is stable, this algorithm is attractive for clinical studies with uncooperative patients. Magn Reson Med 45:167-171, 2001...
Encoding of temporal speech features (formant transients) during binaural and dichotic stimulus application: a whole-head magnetencephalography studyK Mathiak
Department Neurology, University of Tubingen, Tubingen, Germany
Brain Res Cogn Brain Res 10:125-31. 2000..Furthermore, REA during dichotic application of CV syllables seems to be linked to functional dissociation of the two hemispheres during auditory processing...
Stroboscopic articulography using fast magnetic resonance imagingK Mathiak
Department of Neurology, University of Tubingen, Germany
Int J Lang Commun Disord 35:419-25. 2000..g. the entire tongue, the velum and the lower vocal tract. As an example, the method was applied to repetitions of stop consonant-vowel-nasal syllables...
Preattentive processing of consonant vowel syllables at the level of the supratemporal plane: a whole-head magnetencephalography studyK Mathiak
Department of Neurology, University of Tubingen, Tubingen, Germany
Brain Res Cogn Brain Res 8:251-7. 1999..Conceivably, the observed hemispheric difference contributes to prelexical parsing of the auditory signal rather than the encoding of linguistic categories...
Serum leptin levels, body fat deposition, and weight in females with anorexia or bulimia nervosaK Mathiak
Department of Psychosomatics, Medical Center Benjamin Franklin, Free University of Berlin, Germany
Horm Metab Res 31:274-7. 1999..We discuss the necessity for DXA measurements in anorectic patients for prognostic and research purposes...
Serum leptin and body weight in females with anorexia and bulimia nervosaW Kopp
Department of Psychosomatics, Medical Center Benjamin Franklin, Free University of Berlin, Germany
Horm Metab Res 30:272-5. 1998..This dynamic aspect is important specifically in patients with anorexia nervosa during therapeutically induced weight gain...
Contralaterality of cortical auditory processing at the level of the M50/M100 complex and the mismatch field: a whole-head magnetoencephalography studyH Ackermann
Department of Neurology, University of Tuebingen, Germany
Neuroreport 12:1683-7. 2001..These data provide first evidence for a distinct pattern of hemispheric differences at the level of the M50/M100 complex subsequent to monaural application of speech stimuli...
Spatial auditory attention is modulated by tactile primingHans Menning
MEG Center, Center for Neurology, , , 72076, , Germany
Exp Brain Res 164:41-7. 2005..These results show that earlier responses are mainly governed by exogenous stimulus properties whereas cross-sensory interaction is spatially selective at a later (endogenous) processing stage...
Rate-dependent activation of a prefrontal-insular-cerebellar network during passive listening to trains of click stimuli: an fMRI studyH Ackermann
Department of Neurology, University of Tuebingen, Hoppe-Seyler-Str. 3, D-72072 Tuebingen, Germany
Neuroreport 12:4087-92. 2001..Furthermore, these intrasylvian areas seem to join up with the right cerebellum and the left inferior frontal gyrus to a network subserving parsing/timing functions within the auditory-verbal domain...
Neural correlates of duplex perception: a whole-head magnetencephalography studyK Mathiak
Department of Neurology, , Germany
Neuroreport 12:501-6. 2001..These data provide first neurophysiological evidence that the integration of acoustic stimulus elements into a coherent syllable representation constitutes a distinct stage of left-hemisphere speech sound encoding...
A new approach to measure single-event related brain activity using real-time fMRI: feasibility of sensory, motor, and higher cognitive tasksS Posse
Institute of Medicine, Research Center Jülich GmbH, Germany
Hum Brain Mapp 12:25-41. 2001..Real-time fMRI can improve reliability of clinical and research studies and offers new opportunities for studying higher cognitive functions...
Sequential audiovisual interactions during speech perception: a whole-head MEG studyIngo Hertrich
Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Germany
Neuropsychologia 45:1342-54. 2007....
The contribution of the cerebellum to speech production and speech perception: clinical and functional imaging dataHermann Ackermann
Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen
Cerebellum 6:202-13. 2007..The distinct computational operation provided by cerebellar structures within this framework appears to be the concatenation of syllable strings into coarticulated sequences...
Time course and hemispheric lateralization effects of complex pitch processing: evoked magnetic fields in response to rippled noise stimuliIngo Hertrich
Department of Neurology, University of Tubingen, Hoppe Seyler Str 3, D 72076 Tubingen, Germany
Neuropsychologia 42:1814-26. 2004..The observed noise/periodicity interactions, furthermore, might reflect pitch-synchronous spectral evaluation at the level of the left supratemporal plane, triggered by right-hemisphere representation of signal periodicity...
Hearing lips: gamma-band activity during audiovisual speech perceptionJochen Kaiser
MEG Center, Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Gartenstrasse 29, 72074 Tubingen, Germany
Cereb Cortex 15:646-53. 2005..The preceding gamma-band changes over posterior areas may reflect processing of incongruent lip movements in visual motion areas and back-projections to earlier visual cortex...
Transient and phase-locked evoked magnetic fields in response to periodic acoustic signalsIngo Hertrich
Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Hoppe Seyler Strasse 3, D 72076 Tubingen, Germany
Neuroreport 15:1687-90. 2004..Conceivably, these early side-differences in periodicity encoding contribute to or even snowball into hemispheric lateralization effects of higher-order aspects of central-auditory processing such as melody perception...
MEG responses to rippled noise and Huggins pitch reveal similar cortical representationsIngo Hertrich
Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Hoppe Seyler Str 3, D 72076 Tubingen, Germany
Neuroreport 16:193-6. 2005..These results suggest, first, that different pitches converge into a common cortical representation and, second, that the POR encompasses various successive processing stages...
Time course of early audiovisual interactions during speech and nonspeech central auditory processing: a magnetoencephalography studyIngo Hertrich
University of Tubingen, Germany
J Cogn Neurosci 21:259-74. 2009..quot; Thus, visual processing seems to be shaped by linguistic data structures even prior to its fusion with auditory information channel...
Principles of a brain-computer interface (BCI) based on real-time functional magnetic resonance imaging (fMRI)Nikolaus Weiskopf
Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Tubingen, Germany
IEEE Trans Biomed Eng 51:966-70. 2004..Technical and experimental aspects are discussed with respect to neurofeedback. The methodology now allows for studying behavioral effects and strategies of local self-regulation in healthy and diseased subjects...
Mismatch negativity responses in schizophrenia: a combined fMRI and whole-head MEG studyTilo T J Kircher
University of Tübingen Department of Psychiatry, Germany
Am J Psychiatry 161:294-304. 2004..Mismatch negativity response is diminished in patients with schizophrenia. Little is known about the mechanisms of this decreased response, the contribution of the different hemispheres, and its locus of generation...
Hemispheric lateralization of the processing of consonant-vowel syllables (formant transitions): effects of stimulus characteristics and attentional demands on evoked magnetic fieldsIngo Hertrich
Department of Neurology, University of Tubingen, Otfried Müller Street 47, Germany
Neuropsychologia 40:1902-17. 2002..75ms post-stimulus onset) and binaural fusion strategies (ca. 200ms), respectively. Finally, gender interacted with MMF lateralization, indicating different processing strategies in case of artificial speech signals...
Physiological self-regulation of regional brain activity using real-time functional magnetic resonance imaging (fMRI): methodology and exemplary dataNikolaus Weiskopf
Institute of Medical Psychology and Behavioural Neurobiology, University of Tubingen, Tubingen, Germany
Neuroimage 19:577-86. 2003..This methodology of fMRI-feedback can assess voluntary control of circumscribed brain areas. As a further extension, behavioral effects of local self-regulation become accessible as a new field of research...
Processing of dynamic aspects of speech and non-speech stimuli: a whole-head magnetoencephalography studyIngo Hertrich
Neurology Department, University of Tubingen, Hoppe Seyler Str 3, D 72076, Tubingen, Germany
Brain Res Cogn Brain Res 17:130-9. 2003..Signal voicing had no significant main effect on MMF strength despite superior perceptual performance in case of voiced as compared to voiceless target stimuli...
Parametric analysis of rate-dependent hemodynamic response functions of cortical and subcortical brain structures during auditorily cued finger tapping: a fMRI studyAxel Riecker
Department of Neurology, University of Tuebingen, Hoppe Seyler Strasse 3, D 72076, Tuebingen, Germany
Neuroimage 18:731-9. 2003..Caudate nucleus, putamen, and external pallidum of the left hemisphere displayed, by contrast, a negative linear rate/response relationship. The physiological significance of these latter findings remains to be clarified...
Functional cerebral asymmetries of pitch processing during dichotic stimulus application: a whole-head magnetoencephalography studyKlaus Mathiak
Department of Neurology, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
Neuropsychologia 40:585-93. 2002..In conclusion, the present data provide first evidence for functional laterality effects even at the level of preattentive pitch processing within the auditory cortex...
Salt-sensitivity and other predictors of stress-related cardiovascular reactivity in healthy young malesH C Deter
Department of Psychosomatic Medicine and Psychotherapy, Benjamin Franklin Hospital, Free University of Berlin, Germany
Clin Exp Hypertens 23:213-25. 2001..The concept of salt-sensitivity is a novel biological component that might contribute to reactivity research in subjects at high risk for essential hypertension...
Reconstruction of extended cortical sources for EEG and MEG based on a Monte-Carlo-Markov-chain estimatorWilhelm Emil Kincses
MEG-Center, , Germany
Hum Brain Mapp 18:100-10. 2003..Somatosensory evoked magnetic fields analyzed by the method presented suggest that larger extended cortical areas are involved in the processing of combined finger stimulation as compared to single finger stimulation...
Single-shot compensation of image distortions and BOLD contrast optimization using multi-echo EPI for real-time fMRINikolaus Weiskopf
Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Tubingen, Germany
Neuroimage 24:1068-79. 2005..Significant reduction in geometric distortion is shown both for phantom images and human fMRI data. Moreover, sensitivity to the blood oxygen level-dependent (BOLD) effect is increased by weighted summation of the undistorted images...
Self-regulation of local brain activity using real-time functional magnetic resonance imaging (fMRI)Nikolaus Weiskopf
Institute of Medical Psychology and Behavioral Neurobiology, University of Tubingen, Germany
J Physiol Paris 98:357-73. 2004..Voluntary control of abnormal activity in circumscribed brain areas may even be applied as psychophysiological treatment...
Cortisol has different effects on human memory for emotional and neutral stimuliUlrike Rimmele
Graduate School of Neural and Behavioural Sciences, International Max Planck Research School, , Osterbergstrasse 3, 72074 Tuebingen, Germany
Neuroreport 14:2485-8. 2003..We thus confirm a non-linear interaction between cortisol and arousal on memory formation...
An automatic procedure for the analysis of electric and magnetic mismatch negativity based on anatomical brain mappingMikhail Zvyagintsev
Department of Psychiatry and Psychotherapy, University Hospital Aachen, RWTH Aachen, 52074 Aachen, Germany
J Neurosci Methods 168:325-33. 2008..The presented workflow can be performed easily, rapidly, and reliably. This development may open new fields in research and clinical applications of source-based EEG and MEG...
Differential skills of perception of frequencyMichael Schwenzer
RWTH Aachen University, Department of Psychiatry and Psychotherapy, Pauwelsstrasse 30, 52074 Aachen, Germany
Percept Mot Skills 105:236-42. 2007..The auditory tests are likely suitable for assessing distinct skills, but correlations with general cognitive abilities require further investigations...
Automatic processing of semantic relations in fMRI: neural activation during semantic priming of taxonomic and thematic categoriesOlga Sachs
Department of Psychiatry and Psychotherapy, RWTH Aachen University, Pauwelstr 30, D 52074 Aachen, Germany
Brain Res 1218:194-205. 2008..We suggest that the greater involvement of precuneus in the processing of taxonomic relations indicates their reduced salience in the knowledge structure compared to more prominent thematic relations...
Who is telling what from where? A functional magnetic resonance imaging studyKlaus Mathiak
Department of Psychiatry and Psychotherapy, RWTH Aachen University, Germany
Neuroreport 18:405-9. 2007..Furthermore, the findings indicate that voice recognition may depend upon template matching within auditory association cortex whereas the sequencing of phonetic-linguistic information extends to frontal areas...
Real-time functional magnetic resonance imaging: methods and applicationsNikolaus Weiskopf
Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, WC1N 3BG London, UK
Magn Reson Imaging 25:989-1003. 2007....
A magnetoencephalographic study on auditory processing of native and nonnative fricative contrasts in Polish and German listenersSilvia C Lipski
Linguistics Department, University of Konstanz, Germany
Neurosci Lett 415:90-5. 2007..Left hemispheric MMNms only occurred later in nonnative participants. The results are discussed in relation to previous studies suggesting lateralization of speech sound processing...
A new toolbox for combining magnetoencephalographic source analysis and cytoarchitectonic probabilistic data for anatomical classification of dynamic brain activityJürgen Dammers
Institute of Medicin, Research Center Jülich GmbH, 52425 Julich, Germany
Neuroimage 34:1577-87. 2007..Therefore, the adaptation to the respective application and a combination of the objective quantities are discussed...
Toward brain correlates of natural behavior: fMRI during violent video gamesKlaus Mathiak
Department of Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
Hum Brain Mapp 27:948-56. 2006..We relate our findings to the general discussion on social effects of playing first-person shooter games...
Auditory mismatch negativity for speech sound contrasts is modulated by language contextSilvia C Lipski
Max Planck Institute for Neurological Research, Cologne, Germany
Neuroreport 19:1079-83. 2008..This may facilitate elevated concentration on acoustic details that are linguistically relevant...
Differential effects of indoleamines on auditory choice reaction, selective attention, and pitch discriminationMichael Schwenzer
RWTH Aachen University, Department Psychiatry and Psychotherapy, 52074 Aachen, Germany
Neurosci Lett 398:310-3. 2006..We conclude that disorders and drugs affecting the indoleamines must be considered differentially in the auditory and the visual system...
Combining magnetoencephalography and functional magnetic resonance imagingKlaus Mathiak
Department of Psychiatry, RWTH Aachen University D-52074 Aachen, Germany
Int Rev Neurobiol 68:121-48. 2005
Selective influences of cross-modal spatial-cues on preattentive auditory processing: a whole-head magnetoencephalography studyKlaus Mathiak
Department of Psychiatry and Psychotherapy, RWTH Aachen University, Germany
Neuroimage 28:627-34. 2005..Preattentive multisensory integration may provide the neuronal basis for orienting reactions to objects in space and thus for voluntary control of selective attention...
Temporal organization of "internal speech" as a basis for cerebellar modulation of cognitive functionsHermann Ackermann
University of Tuebingen
Behav Cogn Neurosci Rev 3:14-22. 2004..Those areas of the right cerebellar hemisphere thus might provide a common platform for the computation of temporal aspects of verbal utterances in the domains of both speech production and perception...
Pre-attentive detection of syntactic and semantic errorsHans Menning
Psycholinguistics and Cognitive Psychology Unit, Psychological Institute II, University of Munster, Germany
Neuroreport 16:77-80. 2005..The semantic error elicited higher mismatch responses than the syntactic error. This error-sensitive component is interpreted as a very early detector for semantic and syntactic errors...
[Shooting games as leisure permit. Do computer games promote violence? (interview by Dr. Thomas Bisswanger-Heim)]Klaus Mathiak
MMW Fortschr Med 148:15. 2006
