Research Topics
| B M MartinsSummaryCountry: Germany Publications
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Detail Information
Publications
Crystal structure and substrate binding modeling of the uroporphyrinogen-III decarboxylase from Nicotiana tabacum. Implications for the catalytic mechanismB M Martins
Max Planck Institut fur Biochemie, Abteilung Strukturforschung, Am Klopferspitz 18a, 82152 Martinsried bei München, Germany
J Biol Chem 276:44108-16. 2001..The crystallographic dimer appears to represent the protein dimer under physiological conditions. The dimeric arrangement offers a plausible mechanism at least for the first two (out of four) decarboxylation steps...
Crystal structure of 4-hydroxybutyryl-CoA dehydratase: radical catalysis involving a [4Fe-4S] cluster and flavinBerta M Martins
Max Planck Institut Biochemie, Strukturforschung, 82152 Martinsried, Germany
Proc Natl Acad Sci U S A 101:15645-9. 2004..Our results raise interesting questions regarding the mechanism of acyl-CoA dehydrogenases, which are involved in fatty acid oxidation, and address the divergent evolution of the ancestral common gene...
Tobacco uroporphyrinogen-III decarboxylase: characterization, crystallization and preliminary X-ray analysisB M Martins
Max Planck Institut fur Biochemie, Abt Strukturforschung, Am Klopferspitz 18 A, D 82152 Martinsried bei munchen, Germany
Acta Crystallogr D Biol Crystallogr 57:1709-11. 2001..Crystals were obtained in the hexagonal space group P622 with one molecule per asymmetric unit and diffracted to 2.3 A resolution using synchrotron radiation...
Oxygen-dependent coproporphyrinogen-III oxidase from Escherichia coli: one-step purification and biochemical characterisationSofia Macieira
Max Planck Institut fur Biochemie, Abt Strukturforschung, Am Klopferspitz, 18 a, 82152, Martinsried, Germany
FEMS Microbiol Lett 226:31-7. 2003..Both preparations showed a specific activity of 37500 U mg(-1), had a subunit molecular mass of 35 kDa and behaved as a compact shaped dimer. First crystallisation trials produced plate-shaped diffracting crystals...
Structural basis for stereo-specific catalysis in NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentansBerta M Martins
MPI Biochemie, Strukturforschung, Martinsried, Germany
FEBS J 272:269-81. 2005....
New insights into the thermostability of bacterial ferredoxins: high-resolution crystal structure of the seven-iron ferredoxin from Thermus thermophilusS Macedo-Ribeiro
Max Planck Institut fur Biochemie, Abteilung Strukturforschungm, Martinsried, Germany
J Biol Inorg Chem 6:663-74. 2001....
Active site geometry and substrate recognition of the molybdenum hydroxylase quinoline 2-oxidoreductaseIrena Bonin
, , 82152 Martinsried, Germany
Structure 12:1425-35. 2004..The active site protein variants QorE743V and QorE743D were analyzed to assess the catalytic role of E743...
Radical-mediated dehydration reactions in anaerobic bacteriaWolfgang Buckel
Laboratorium für Mikrobiologie, Fachbereich Biologie, Philipps Universitat, D 35032 Marburg, Germany
Biol Chem 386:951-9. 2005..The structure of the FAD- and [4Fe-4S]-containing homotetrameric dehydratase is related to that of acyl-CoA dehydrogenases, suggesting a radical-based mechanism for both flavoproteins...
Basic requirements for a metal-binding site in a protein: the influence of loop shortening on the cupredoxin azurinChan Li
Institute for Cell and Molecular Biosciences, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, United Kingdom
Proc Natl Acad Sci U S A 103:7258-63. 2006....
HTHP: a novel class of hexameric, tyrosine-coordinated heme proteinsJae Hun Jeoung
Laboratorium Proteinkristallographie, Universitat Bayreuth, Universitatsstrasse 30, 95447 Bayreuth, Germany
J Mol Biol 368:1122-31. 2007..We therefore propose that HTHP is the prototype of a new class of heme proteins...
