Research Topics
| Katharina M Picker-FreyerSummaryAffiliation: Martin Luther University Country: Germany Publications
| Collaborators
|
Detail Information
Publications
The 3-D model: experimental testing of the parameters d, e, and omega and validation of the analysisKatharina Maria Picker-Freyer
Martin Luther University Halle Wittenberg, Institute of Pharmaceutics and Biopharmaceutics, Wolfgang Langenbeck Str 4, 06120 Halle Saale, Germany
J Pharm Sci 96:1408-17. 2007..The significance of the three parameters is fully given. It is no longer necessary to use two separate methods to differentiate between time- and pressure-dependent deformations...
Physical mechanical and tablet formation properties of hydroxypropylcellulose: in pure form and in mixturesKatharina M Picker-Freyer
Martin Luther University Halle Wittenberg, Institute of Pharmaceutics and Biopharmaceutics, Wolfgang Langenbeck Str 4, 06120 Halle Saale, Germany
AAPS PharmSciTech 8:E92. 2007..Plasticity and crushing force of formed tablets was increased. In conclusion, HPC is characterized by strong plastic deformation properties, which are molecular weight and particle size dependent...
Evaluation of the material and tablet formation properties of modified forms of Dioscorea starchesOluwatoyin A Odeku
Department of Pharmaceutics and Biopharmaceutics, Institute of Pharmacy, Martin Luther University Halle Wittenberg, Halle Saale, Germany
Drug Dev Ind Pharm 35:1389-406. 2009..Thus, the modified Dioscorea starches showed potentials for development as new excipients in solid dosage form design, and they could be useful as disintegrants or for Soft tableting...
Material and tablet properties of pregelatinized (thermally modified) Dioscorea starchesOluwatoyin A Odeku
Division of Pharmaceutics and Biopharmaceutics, Martin Luther University Halle Wittenberg, Wolfgang Langenbeck Strasse 4, Halle Saale, Germany
Eur J Pharm Biopharm 70:357-71. 2008....
Simulation of roller compaction with subsequent tableting and characterization of lactose and microcrystalline celluloseStephanie Hein
Martin Luther University Halle Wittenberg, Institute of Pharmacy, Division of Pharmaceutics and Biopharmaceutics, Halle, Germany
Pharm Dev Technol 13:523-32. 2008..With the simulation of roller compaction process one is able to find qualified materials for use in roller compaction without the necessity of a great deal of material and time...
Tableting and tablet properties of alginates: characterisation and potential for Soft TabletingWolfgang Schmid
Institute of Pharmacy, Martin Luther University Halle Wittenberg, Halle, Germany
Eur J Pharm Biopharm 72:165-72. 2009..The elastic alginates inflicted less damage on the pellets than the plastic MCC. Thus, all alginates were more appropriate for tableting pressure sensitive materials than MCC...
Evaluation of powder and tableting properties of chitosanKatharina M Picker-Freyer
Martin Luther University Halle Wittenberg, Institute of Pharmaceutical Technology and Biopharmacy, Halle Saale, Germany
AAPS PharmSciTech 7:75. 2006..In summation, chitosans show plastic deformation during compression combined with high elasticity after tableting. Highly mechanically stable tablets result...
Evaluation of the compaction of sulfathiazole polymorphsKatharina Maria Picker-Freyer
Institute of Pharmaceutics and Biopharmaceutics, Martin Luther University Halle Wittenberg, Wolfgang Langenbeck Str 4, 06120 Halle Saale, Germany
J Pharm Sci 96:2111-24. 2007..However, in this system, there was little correspondence between the macroscopic and microscopic measurements, and thus particle-particle interactions may to be of paramount importance...
Compaction of lactose drug mixtures: quantification of the extent of incompatibility by FT-Raman spectroscopyAnett Flemming
Martin Luther University Halle Wittenberg, Institute of Pharmaceutical Technology and Biopharmacy, Halle Saale, Germany
Eur J Pharm Biopharm 68:802-10. 2008..In conclusion, FT-Raman spectroscopy is a fast and valuable tool for a quantitative determination of the extents of incompatibility in solid dosage forms...
Characterization of acid modified Dioscorea starches as direct compression excipientOluwatoyin A Odeku
Faculty of Pharmacy, Institute of Pharmaceutical Technology and Biopharmacy, Martin Luther University Halle Wittenberg, Halle Saale, Germany
Pharm Dev Technol 14:259-70. 2009..The result indicates that acid modified starch tablets showed higher crushing force and acceptable disintegration time and could therefore be useful as directly compressible excipient...
