Katharina M Picker-Freyer

Summary

Affiliation: Martin Luther University
Country: Germany

Publications

  1. pmc Physical mechanical and tablet formation properties of hydroxypropylcellulose: in pure form and in mixtures
    Katharina M Picker-Freyer
    Martin Luther University Halle Wittenberg, Institute of Pharmaceutics and Biopharmaceutics, Wolfgang Langenbeck Str 4, 06120 Halle Saale, Germany
    AAPS PharmSciTech 8:E92. 2007
  2. ncbi request reprint The 3-D model: experimental testing of the parameters d, e, and omega and validation of the analysis
    Katharina Maria Picker-Freyer
    Martin Luther University Halle Wittenberg, Institute of Pharmaceutics and Biopharmaceutics, Wolfgang Langenbeck Str 4, 06120 Halle Saale, Germany
    J Pharm Sci 96:1408-17. 2007
  3. ncbi request reprint Evaluation of tableting and tablet properties of Kollidon SR: the influence of moisture and mixtures with theophylline monohydrate
    Karsten Hauschild
    Martin Luther University Halle Wittenberg, Institute of Pharmaceutical Technology and Biopharmacy, Halle Saale, Germany
    Pharm Dev Technol 11:125-40. 2006
  4. doi request reprint Evaluation of the material and tablet formation properties of modified forms of Dioscorea starches
    Oluwatoyin A Odeku
    Department of Pharmaceutics and Biopharmaceutics, Institute of Pharmacy, Martin Luther University Halle Wittenberg, Halle Saale, Germany
    Drug Dev Ind Pharm 35:1389-406. 2009
  5. doi request reprint Material and tablet properties of pregelatinized (thermally modified) Dioscorea starches
    Oluwatoyin A Odeku
    Division of Pharmaceutics and Biopharmaceutics, Martin Luther University Halle Wittenberg, Wolfgang Langenbeck Strasse 4, Halle Saale, Germany
    Eur J Pharm Biopharm 70:357-71. 2008
  6. ncbi request reprint Simulation of roller compaction with subsequent tableting and characterization of lactose and microcrystalline cellulose
    Stephanie Hein
    Martin Luther University Halle Wittenberg, Institute of Pharmacy, Division of Pharmaceutics and Biopharmaceutics, Halle, Germany
    Pharm Dev Technol 13:523-32. 2008
  7. doi request reprint Tableting and tablet properties of alginates: characterisation and potential for Soft Tableting
    Wolfgang Schmid
    Institute of Pharmacy, Martin Luther University Halle Wittenberg, Halle, Germany
    Eur J Pharm Biopharm 72:165-72. 2009
  8. ncbi request reprint Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation
    Karsten Hauschild
    Faculty of Pharmacy, Institute of Pharmaceutical Technology and Biopharmacy, Martin Luther University Halle Wittenberg, Wolfgang Langenbeck Strasse 4, 06120 Halle Saale, Germany
    AAPS PharmSci 6:e16. 2004
  9. pmc Evaluation of powder and tableting properties of chitosan
    Katharina M Picker-Freyer
    Martin Luther University Halle Wittenberg, Institute of Pharmaceutical Technology and Biopharmacy, Halle Saale, Germany
    AAPS PharmSciTech 7:75. 2006
  10. ncbi request reprint Evaluation of the compaction of sulfathiazole polymorphs
    Katharina Maria Picker-Freyer
    Institute of Pharmaceutics and Biopharmaceutics, Martin Luther University Halle Wittenberg, Wolfgang Langenbeck Str 4, 06120 Halle Saale, Germany
    J Pharm Sci 96:2111-24. 2007

Collaborators

  • Oluwatoyin A Odeku
  • Karsten Hauschild
  • Wolfgang Schmid
  • Stephanie Hein
  • Anett Flemming
  • John Langridge

Detail Information

Publications12

  1. pmc Physical mechanical and tablet formation properties of hydroxypropylcellulose: in pure form and in mixtures
    Katharina M Picker-Freyer
    Martin Luther University Halle Wittenberg, Institute of Pharmaceutics and Biopharmaceutics, Wolfgang Langenbeck Str 4, 06120 Halle Saale, Germany
    AAPS PharmSciTech 8:E92. 2007
    ..Plasticity and crushing force of formed tablets was increased. In conclusion, HPC is characterized by strong plastic deformation properties, which are molecular weight and particle size dependent...
  2. ncbi request reprint The 3-D model: experimental testing of the parameters d, e, and omega and validation of the analysis
    Katharina Maria Picker-Freyer
    Martin Luther University Halle Wittenberg, Institute of Pharmaceutics and Biopharmaceutics, Wolfgang Langenbeck Str 4, 06120 Halle Saale, Germany
    J Pharm Sci 96:1408-17. 2007
    ..The significance of the three parameters is fully given. It is no longer necessary to use two separate methods to differentiate between time- and pressure-dependent deformations...
  3. ncbi request reprint Evaluation of tableting and tablet properties of Kollidon SR: the influence of moisture and mixtures with theophylline monohydrate
    Karsten Hauschild
    Martin Luther University Halle Wittenberg, Institute of Pharmaceutical Technology and Biopharmacy, Halle Saale, Germany
    Pharm Dev Technol 11:125-40. 2006
    ..Kollidon SR and Kollidon SR mixtures exhibited a higher compactibility than MCC and MCC mixtures. The differences became smaller with increasing theophylline content...
  4. doi request reprint Evaluation of the material and tablet formation properties of modified forms of Dioscorea starches
    Oluwatoyin A Odeku
    Department of Pharmaceutics and Biopharmaceutics, Institute of Pharmacy, Martin Luther University Halle Wittenberg, Halle Saale, Germany
    Drug Dev Ind Pharm 35:1389-406. 2009
    ..Thus, the modified Dioscorea starches showed potentials for development as new excipients in solid dosage form design, and they could be useful as disintegrants or for Soft tableting...
  5. doi request reprint Material and tablet properties of pregelatinized (thermally modified) Dioscorea starches
    Oluwatoyin A Odeku
    Division of Pharmaceutics and Biopharmaceutics, Martin Luther University Halle Wittenberg, Wolfgang Langenbeck Strasse 4, Halle Saale, Germany
    Eur J Pharm Biopharm 70:357-71. 2008
    ....
  6. ncbi request reprint Simulation of roller compaction with subsequent tableting and characterization of lactose and microcrystalline cellulose
    Stephanie Hein
    Martin Luther University Halle Wittenberg, Institute of Pharmacy, Division of Pharmaceutics and Biopharmaceutics, Halle, Germany
    Pharm Dev Technol 13:523-32. 2008
    ..With the simulation of roller compaction process one is able to find qualified materials for use in roller compaction without the necessity of a great deal of material and time...
  7. doi request reprint Tableting and tablet properties of alginates: characterisation and potential for Soft Tableting
    Wolfgang Schmid
    Institute of Pharmacy, Martin Luther University Halle Wittenberg, Halle, Germany
    Eur J Pharm Biopharm 72:165-72. 2009
    ..The elastic alginates inflicted less damage on the pellets than the plastic MCC. Thus, all alginates were more appropriate for tableting pressure sensitive materials than MCC...
  8. ncbi request reprint Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation
    Karsten Hauschild
    Faculty of Pharmacy, Institute of Pharmaceutical Technology and Biopharmacy, Martin Luther University Halle Wittenberg, Wolfgang Langenbeck Strasse 4, 06120 Halle Saale, Germany
    AAPS PharmSci 6:e16. 2004
    ..However, the part of the powder that was irreversibly compressed was much lower than was observed for the single substances. This behavior is caused by an interaction between the components, which in StarLac is prevented by spray drying...
  9. pmc Evaluation of powder and tableting properties of chitosan
    Katharina M Picker-Freyer
    Martin Luther University Halle Wittenberg, Institute of Pharmaceutical Technology and Biopharmacy, Halle Saale, Germany
    AAPS PharmSciTech 7:75. 2006
    ..In summation, chitosans show plastic deformation during compression combined with high elasticity after tableting. Highly mechanically stable tablets result...
  10. ncbi request reprint Evaluation of the compaction of sulfathiazole polymorphs
    Katharina Maria Picker-Freyer
    Institute of Pharmaceutics and Biopharmaceutics, Martin Luther University Halle Wittenberg, Wolfgang Langenbeck Str 4, 06120 Halle Saale, Germany
    J Pharm Sci 96:2111-24. 2007
    ..However, in this system, there was little correspondence between the macroscopic and microscopic measurements, and thus particle-particle interactions may to be of paramount importance...
  11. doi request reprint Characterization of acid modified Dioscorea starches as direct compression excipient
    Oluwatoyin A Odeku
    Faculty of Pharmacy, Institute of Pharmaceutical Technology and Biopharmacy, Martin Luther University Halle Wittenberg, Halle Saale, Germany
    Pharm Dev Technol 14:259-70. 2009
    ..The result indicates that acid modified starch tablets showed higher crushing force and acceptable disintegration time and could therefore be useful as directly compressible excipient...
  12. ncbi request reprint Compaction of lactose drug mixtures: quantification of the extent of incompatibility by FT-Raman spectroscopy
    Anett Flemming
    Martin Luther University Halle Wittenberg, Institute of Pharmaceutical Technology and Biopharmacy, Halle Saale, Germany
    Eur J Pharm Biopharm 68:802-10. 2008
    ..In conclusion, FT-Raman spectroscopy is a fast and valuable tool for a quantitative determination of the extents of incompatibility in solid dosage forms...