K Peters

Summary

Affiliation: Martin Luther University
Country: Germany

Publications

  1. ncbi request reprint A new class of potent reversible inhibitors of metallo-proteinases: C-terminal thiol-peptides as zinc-coordinating ligands
    K Peters
    Faculty of Medicine, Institute of Physiological Chemistry, Martin Luther University, Halle Wittenberg, Halle Saale, Germany
    J Enzyme Inhib 16:339-50. 2001
  2. ncbi request reprint Crystal structure of subtilisin DY, a random mutant of subtilisin Carlsberg
    S Eschenburg
    European Molecular Biology Laboratory, Institute of Physiological Chemistry, Hamburg, Germany
    Eur J Biochem 257:309-18. 1998
  3. ncbi request reprint Purification of soluble and membrane-bound proteases with substrate-analogous inhibitors by affinity chromatography
    G Jahreis
    Institute of Physiological Chemistry, Faculty of Medicine, Martin Luther University, Hollystrasse 1, D-06097 Halle (Saale, Germany
    J Biochem Biophys Methods 49:491-505. 2001

Collaborators

Detail Information

Publications3

  1. ncbi request reprint A new class of potent reversible inhibitors of metallo-proteinases: C-terminal thiol-peptides as zinc-coordinating ligands
    K Peters
    Faculty of Medicine, Institute of Physiological Chemistry, Martin Luther University, Halle Wittenberg, Halle Saale, Germany
    J Enzyme Inhib 16:339-50. 2001
    ..The strongest inhibition was found with Z-Pro-Leu-CA-SH (Ki = 30 microM). Substitution of the N-protecting benzyloxycarbonyl residue towards the acetyl group in the peptide inhibitor, the inhibition constant decreased about 25 times...
  2. ncbi request reprint Crystal structure of subtilisin DY, a random mutant of subtilisin Carlsberg
    S Eschenburg
    European Molecular Biology Laboratory, Institute of Physiological Chemistry, Hamburg, Germany
    Eur J Biochem 257:309-18. 1998
    ....
  3. ncbi request reprint Purification of soluble and membrane-bound proteases with substrate-analogous inhibitors by affinity chromatography
    G Jahreis
    Institute of Physiological Chemistry, Faculty of Medicine, Martin Luther University, Hollystrasse 1, D-06097 Halle (Saale, Germany
    J Biochem Biophys Methods 49:491-505. 2001
    ..As a new type of ligands, spacer-bound peptidyl chloromethyl ketones are presented for a specific and oriented immobilization of proteinases. Oriented-immobilized cathepsin B was used to isolate antibodies against this enzyme...