M Klintschar

Summary

Affiliation: Martin Luther University
Country: Germany

Publications

  1. ncbi request reprint Sudden cardiac death in hereditary hemochromatosis: an underestimated cause of death?
    M Klintschar
    Institute for Legal Medicine, University Halle Wittenberg, Franzosenweg 1, 06112 Halle, Germany
    Int J Legal Med 118:174-7. 2004
  2. ncbi request reprint Persisting fetal microchimerism does not interfere with forensic Y-chromosome typing
    M Klintschar
    Institute of Legal Medicine, University Halle Wittenberg, Franzosenweg 1, Halle D 06112, Germany
    Forensic Sci Int 139:151-4. 2004
  3. ncbi request reprint Haplotype studies support slippage as the mechanism of germline mutations in short tandem repeats
    Michael Klintschar
    Institute of Legal Medicine, University Halle, Germany
    Electrophoresis 25:3344-8. 2004
  4. ncbi request reprint TH01, a tetrameric short tandem repeat locus in the tyrosine hydroxylase gene: association with myocardial hypertrophy and death from myocardial infarction?
    Michael Klintschar
    Institut fur Rechtsmedizin, Martin Luther Universitat Halle Wittenberg, Franzosenweg 1, 06097 Halle Saale, Germany
    Dis Markers 21:9-13. 2005
  5. ncbi request reprint Fetal microchimerism in Hashimoto's thyroiditis: a quantitative approach
    Michael Klintschar
    Institute of Legal Medicine, University Halle Wittenberg, Halle Saale, Germany
    Eur J Endocrinol 154:237-41. 2006
  6. ncbi request reprint Fatal truck-bicycle accident involving dragging for 45 km
    M Klintschar
    Institut fur Rechtsmedizin, Martin Luther Universitat Halle Wittenberg, Franzosenweg 1, 06112, Halle Saale, Germany
    Int J Legal Med 117:226-8. 2003
  7. ncbi request reprint DNA polymorphisms in the tyrosine hydroxylase and GNB3 genes: association with unexpected death from acute myocardial infarction and increased heart weight
    M Klintschar
    Institute of Legal Medicine, Martin Luther University Halle Wittenberg, Franzosenweg 1, D06112 Halle, Germany
    Forensic Sci Int 153:142-6. 2005
  8. ncbi request reprint Evidence of fetal microchimerism in Hashimoto's thyroiditis
    M Klintschar
    Institute of Legal Medicine, Martin Luther University Halle Wittenberg, D06112 Halle Saale Germany
    J Clin Endocrinol Metab 86:2494-8. 2001
  9. ncbi request reprint Significant differences between Yemenite and Egyptian STR profiles and the influence on frequency estimations in Arabs
    M Klintschar
    Department of Legal Medicine, University of Halle, Franzosenweg 1, D 06112 Halle Saale, Germany
    Int J Legal Med 114:211-4. 2001
  10. ncbi request reprint Population genetic data, comparison of the repeat structure and mutation events of two short STRs
    Peter Wiegand
    Institute of Pathology and Legal Medicine, Department of Legal Medicine, University Hospital, Prittwitzstrasse 6, 89075 Ulm, Germany
    Int J Legal Med 116:258-61. 2002

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Sudden cardiac death in hereditary hemochromatosis: an underestimated cause of death?
    M Klintschar
    Institute for Legal Medicine, University Halle Wittenberg, Franzosenweg 1, 06112 Halle, Germany
    Int J Legal Med 118:174-7. 2004
    ..This case demonstrates that genetic screening alone might not be sufficient to identify all persons at risk to developing HH...
  2. ncbi request reprint Persisting fetal microchimerism does not interfere with forensic Y-chromosome typing
    M Klintschar
    Institute of Legal Medicine, University Halle Wittenberg, Franzosenweg 1, Halle D 06112, Germany
    Forensic Sci Int 139:151-4. 2004
    ....
  3. ncbi request reprint Haplotype studies support slippage as the mechanism of germline mutations in short tandem repeats
    Michael Klintschar
    Institute of Legal Medicine, University Halle, Germany
    Electrophoresis 25:3344-8. 2004
    ..By doing so we were able to exclude UCO in each case. Moreover, we were able to identify the mutations as one-repeat contractions/expansions. Our data thus support slippage as the mechanism of germline mutations in STRs...
  4. ncbi request reprint TH01, a tetrameric short tandem repeat locus in the tyrosine hydroxylase gene: association with myocardial hypertrophy and death from myocardial infarction?
    Michael Klintschar
    Institut fur Rechtsmedizin, Martin Luther Universitat Halle Wittenberg, Franzosenweg 1, 06097 Halle Saale, Germany
    Dis Markers 21:9-13. 2005
    ..This could be explained by a relatively small impact of the TH01 genotype on the blood pressure or by counteraction of another mechanism related to catecholamines and their effect on the human body...
  5. ncbi request reprint Fetal microchimerism in Hashimoto's thyroiditis: a quantitative approach
    Michael Klintschar
    Institute of Legal Medicine, University Halle Wittenberg, Halle Saale, Germany
    Eur J Endocrinol 154:237-41. 2006
    ..The goal of the study was to reliably estimate the number of fetal engrafted cells and to further investigate factors influencing the development of MCH...
  6. ncbi request reprint Fatal truck-bicycle accident involving dragging for 45 km
    M Klintschar
    Institut fur Rechtsmedizin, Martin Luther Universitat Halle Wittenberg, Franzosenweg 1, 06112, Halle Saale, Germany
    Int J Legal Med 117:226-8. 2003
    ..The reports of the technical expert and the forensic pathologist led the prosecutor to drop the case against the truck driver for manslaughter...
  7. ncbi request reprint DNA polymorphisms in the tyrosine hydroxylase and GNB3 genes: association with unexpected death from acute myocardial infarction and increased heart weight
    M Klintschar
    Institute of Legal Medicine, Martin Luther University Halle Wittenberg, Franzosenweg 1, D06112 Halle, Germany
    Forensic Sci Int 153:142-6. 2005
    ....
  8. ncbi request reprint Evidence of fetal microchimerism in Hashimoto's thyroiditis
    M Klintschar
    Institute of Legal Medicine, Martin Luther University Halle Wittenberg, D06112 Halle Saale Germany
    J Clin Endocrinol Metab 86:2494-8. 2001
    ....
  9. ncbi request reprint Significant differences between Yemenite and Egyptian STR profiles and the influence on frequency estimations in Arabs
    M Klintschar
    Department of Legal Medicine, University of Halle, Franzosenweg 1, D 06112 Halle Saale, Germany
    Int J Legal Med 114:211-4. 2001
    ....
  10. ncbi request reprint Population genetic data, comparison of the repeat structure and mutation events of two short STRs
    Peter Wiegand
    Institute of Pathology and Legal Medicine, Department of Legal Medicine, University Hospital, Prittwitzstrasse 6, 89075 Ulm, Germany
    Int J Legal Med 116:258-61. 2002
    ..Two isolated cases of a new mutation could be confirmed for D7S1517. The alleles of these two family constellations were characterised by sequencing and the probable mutational events were demonstrated...
  11. ncbi request reprint "Paterniplex", a highly discriminative decaplex STR multiplex tailored for investigating special problems in paternity testing
    Thomas Betz
    Institute for Legal Medicine, Martin Luther University Halle Wittenberg, Halle, Germany
    Electrophoresis 28:3868-74. 2007
    ....
  12. ncbi request reprint Y-chromosomal STR haplotype analysis reveals surname-associated strata in the East-German population
    Uta Dorothee Immel
    Department of Legal Medicine, Martin Luther University, Halle Saale, Germany
    Eur J Hum Genet 14:577-82. 2006
    ..Our results suggest that surnames may provide a simple means to stratify, and thereby to render more efficient, Y-chromosomal analyses of Central Europeans that target more ancient events...
  13. ncbi request reprint Y chromosome polymorphisms and haplotypes in South Saxony-Anhalt (Germany)
    Uta Dorothee Immel
    Department of Legal Medicine, Martin Luther University Halle, Franzosenweg 1, 06112 Halle, Saale, Germany
    Forensic Sci Int 155:211-5. 2005
    ..Two hundred and six different haplotypes were obtained. The haplotype diversity was 0.8915. Using AMOVA significant differences were observed to populations from Poland and Croatia...
  14. pmc Mutation rate in human microsatellites: influence of the structure and length of the tandem repeat
    B Brinkmann
    Institut fur Rechtsmedizin, Westfalische Wilhelms Universitat, Munster, Germany
    Am J Hum Genet 62:1408-15. 1998
    ..Our data demonstrate that mutation rates of different loci can differ by several orders of magnitude and that different alleles at one locus exhibit different mutation rates...
  15. ncbi request reprint Asian online Y-STR Haplotype Reference Database
    Ruediger Lessig
    Institute of Legal Medicine, University of Leipzig, Johannisallee 28, D 04103 Leipzig, Germany
    Leg Med (Tokyo) 5:S160-3. 2003
    ..All databases are maintained and curated at the Institute of Legal Medicine, Humboldt-University, Berlin and will soon be fused to a global repository including populations from all continents...
  16. ncbi request reprint Polymerase slippage in relation to the uniformity of tetrameric repeat stretches
    Michael Klintschar
    Institute of Legal Medicine, Martin Luther University, Halle Wittenberg, Halle Wittenberg, Germany
    Forensic Sci Int 135:163-6. 2003
    ..82 for selected D7S1517 alleles) which confirmed the hypothesis that polymerase slippage correlates to the length of repeat stretches consisting of uniform repeats...
  17. doi request reprint A functional polymorphism in the tyrosine hydroxylase gene indicates a role of noradrenalinergic signaling in sudden infant death syndrome
    Michael Klintschar
    Institute of Legal Medicine, Georg August University Gottingen, Gottingen, Germany
    J Pediatr 153:190-3. 2008
    ..Catecholamines may contribute to the cause of sudden infant death syndrome (SIDS). TH01, a tetrameric short tandem repeat marker in the tyrosine hydroxylase gene, regulates gene expression and catecholamine production...
  18. doi request reprint Marfan syndrome: clinical consequences resulting from a medicolegal autopsy of a case of sudden death due to aortic rupture
    M Klintschar
    Department of Legal Medicine, Universitatsmedizin Gottingen, Robert Koch Str 40, 37075, Gottingen, Germany
    Int J Legal Med 123:55-8. 2009
    ..We argue that in all sudden and unexpected deaths in young persons up to 35 years an autopsy should be performed, not only to detect unnatural causes of death but also to identify heritable diseases and thus aid the relatives...
  19. ncbi request reprint Identification of forensic samples by using an infrared-based automatic DNA sequencer
    Ugo Ricci
    Genetics and Molecular Medicine Unit, A Meyer Hospital, University of Florence, A Meyer Hospital, Via Luca Giordano 13, 50132 Florence, Italy
    Croat Med J 44:299-305. 2003
    ..The comparability of the results with the widespread UV methods suggests that it is possible to exchange data between laboratories using the same core group of markers but different primer sets and detection methods...
  20. ncbi request reprint Population data on the AmpFlSTR SGM plus PCR amplification kit in Germans and Austrians
    Barbara Reichenpfader
    Department of Legal Medicine, University Graz, Universitatsplatz 4, A8010 Graz, Austria
    Forensic Sci Int 132:84-6. 2003
    ..All loci met Hardy-Weinberg expectations. In 212 meioses per locus, one mutation event for D19S433 was observed...
  21. ncbi request reprint Y-chromosome analysis in Egypt suggests a genetic regional continuity in Northeastern Africa
    Franz Manni
    Laboratoire d Anthropologie Biologique CNRS FRE 2292 Musée de l Homme MNHN, Paris, France
    Hum Biol 74:645-58. 2002
    ....
  22. ncbi request reprint Fetal microchimerism is common in normal and diseased vulvar skin
    Sigrid Regauer
    J Invest Dermatol 122:1059-60. 2004