S Diederich

..The presentation focuses on CT and MRI of chest and abdominal tumors and specifically excludes positron emission tomography/CT and brain tumors...

..computed tomography promises better sensitivity. Other modern tests such as fibre optic bronchoscopy, analysis of molecular markers or genetic testing in serum, sputum or exhaled air are not yet ready for clinical practice...

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..Patient acceptance is good. Further studies are required on indications, technical requirements, therapy control and particularly long-term results...

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..To assess feasibility, results and complications in image-guided biopsies using a single needle design in various organs...

..Invasive procedures are only required for growing nodules. Stable nodules require further follow-up and decreasing nodules are considered benign...

..If imaging suggests irresectable disease, histologic confirmation may be required in order not to prevent curative resection in false positive findings...

..At the same time, other techniques for early diagnosis of lung cancer are under evaluation, such as sophisticated methods of sputum analysis, molecular markers in the blood and analysis of exhaled air...

..Please include a few sentences as an abstract of the paper so that it will have a presence in the online databases...

..Multiple new pulmonary nodules were demonstrated at chest radiography in a 69-year-old woman who had been treated for breast cancer ten years previously...

..As these may be negative on positron emission tomography and slow growing, the diagnostic algorithms that are used for solid nodules have to be modified for non-solid nodules...

..The 6th edition was published in 2002 and the 7th edition was published in 2009. The 7th edition became current from January 2010 on...

..This review describes the physiology and pathophysiology of GGO, illustrates different examples of common diseases presenting with GGO and reviews how GGO may be used for diagnosis and differential diagnosis of pulmonary disease...

..Only then general recommendations to screen individuals at risk of lung cancer with low-dose CT should be made. It can be hoped that international cooperation will succeed in providing results as early as possible...

..It is hoped that through international cooperation data from these trials can be pooled to allow for statistically significant conclusions as early as possible...

..Recently, accuracy of low dose CT has been shown to be similar to conventional dose CT. The goal of the current study was to assess the findings of low dose CT of the chest in heavy smokers...

..Prior to a wide application of the technique in clinical routine more data are required as to inclusion criteria, examination intervals and the effect of screening on mortality reduction...

..Most importantly, further data are required to clarify whether lung cancer screening using low-dose CT can actually reduce mortality from lung cancer...

..The only relatively common complication of pneumothorax can and should be controlled by the interventional radiologist by aspiration or drainage...

..We present an example of a nodule with strong contrast enhancement and a doubling time of approximately 260 days, which histologically represented a benign inflammatory pseudotumour...

..To compare the number of pulmonary nodules detected at helical low- and standard-dose computed tomography (CT) and to investigate the diagnostic value of low-dose CT with a radiation exposure equivalent to that used at chest radiography...

..To compare the diagnostic performance of selenium-based digital radiography with that of conventional screen-film radiography and storage phosphor radiography for the detection of bone lesions simulating osteolyses...

..Computed tomography was superior to radiography not only in characterization of lesions but could also demonstrate pulmonary involvement when the radiograph was normal and should, therefore, be used liberally in addition to radiography...

..For detection of nodules MIP 15 was slightly superior to MIP 30...

..Resolving pulmonary nodules were mostly < or =10 mm, peripherally located, solid, well-defined, and non-lobulated. Most resolve completely within a variable interval ranging from several days to years...

..For the precise demonstration of small details (e.g. structures of the right upper quadrant), a protocol with standard radiation exposure (> or =100 mAs) was superior...

..Inflammatory nodules are well vascularized and may regress spontaneously; their differentiation from malignant lesions, however, is usually difficult...

..To present prevalence screening data from a nonrandomized screening trial by using low-dose computed tomography (CT) and a simple algorithm based on the size and attenuation of detected nodules to guide diagnostic work-up...

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..An algorithm for diagnostic workup of incidentally detected small pulmonary nodules in subjects without known malignancy is proposed in this article...

..Computer-aided diagnosis improves detection of pulmonary nodules at spiral CT and is a valuable second opinion in a clinical setting for lung cancer screening despite of its still limited sensitivity...

..5 to 6.6% for interobserver agreement. Precision of in vivo volumetric analysis of nodules with an automatic volumetry software tool was sufficiently high to allow for detection of clinically relevant growth in small pulmonary nodules...

..No difference between sensitivities at LDCT and SDCT for detection of small nodules was observed...

..Nodule volumetry is accurate with a reasonable volume error in data from different scanner vendors. This may have an important impact for intraindividual follow-up studies...

..To evaluate a large area, cesium iodide amorphous silicon flat-panel detector (CsI/a-Si) at 3 tube voltages to detect simulated interstitial lung disease, nodules, and catheters...

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..To assess image quality and exposure dose requirements of a flat-panel detector system versus screen-film and storage-phosphor systems for radiographic depiction of the lumbar spine in Cynomolgus monkeys as a pediatric model...