StrauÃŸ O, Reichhart N, Gómez N, MÃ¼ller C. Contribution of Ion Channels in Calcium Signaling Regulating Phagocytosis: MaxiK, Cav1.3 and Bestrophin-1. Adv Exp Med Biol. 2016;854:739-44 pubmed publisher
..Thus we suggest that mutant bestrophin-1 leads to an impaired regulation of the POS phagocytosis by the RPE which would explain the fast lipofuscin accumulation in Best patients. ..