A R Luft

Summary

Country: Germany

Publications

  1. ncbi request reprint Motor skill learning depends on protein synthesis in motor cortex after training
    Andreas R Luft
    Department of General Neurology and Hertie Institute for Clinical Brain Research, University of Tubingen, 72076 Tubingen, Germany
    J Neurosci 24:6515-20. 2004
  2. ncbi request reprint Protein synthesis inhibition blocks consolidation of an acrobatic motor skill
    Andreas R Luft
    Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, 72076 Tubingen, Germany
    Learn Mem 11:379-82. 2004
  3. ncbi request reprint Transcranial magnetic stimulation in the rat
    A R Luft
    Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA
    Exp Brain Res 140:112-21. 2001
  4. ncbi request reprint Frequency and predictors for angiographically improved inflow of contrast medium after carotid angioplasty and stenting
    A R Luft
    Division of Neurosciences, Johns Hopkins University, Baltimore, MD 21287, USA
    Neuroradiology 43:877-83. 2001
  5. ncbi request reprint Lesion location alters brain activation in chronically impaired stroke survivors
    Andreas R Luft
    Department of Neurology, University of Maryland, Baltimore, MD 21287, USA
    Neuroimage 21:924-35. 2004
  6. ncbi request reprint Modulation of rodent cortical motor excitability by somatosensory input
    Andreas R Luft
    Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA
    Exp Brain Res 142:562-9. 2002
  7. ncbi request reprint Early restitution of electrocorticogram predicts subsequent behavioral recovery from cardiac arrest
    Andreas R Luft
    Department of Neurology, Johns Hopkins University, Baltimore, Maryland, USA
    J Clin Neurophysiol 19:540-6. 2002
  8. ncbi request reprint Comparing brain activation associated with isolated upper and lower limb movement across corresponding joints
    Andreas R Luft
    Department of Neurology, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Hum Brain Mapp 17:131-40. 2002
  9. ncbi request reprint Brain activation of lower extremity movement in chronically impaired stroke survivors
    Andreas R Luft
    Division of Brain Injury Outcomes, Department of Neurology, Johns Hopkins University, Baltimore, MD 21218, USA
    Neuroimage 26:184-94. 2005
  10. doi request reprint Motor learning transiently changes cortical somatotopy
    Katiuska Molina-Luna
    Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    Neuroimage 40:1748-54. 2008

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Motor skill learning depends on protein synthesis in motor cortex after training
    Andreas R Luft
    Department of General Neurology and Hertie Institute for Clinical Brain Research, University of Tubingen, 72076 Tubingen, Germany
    J Neurosci 24:6515-20. 2004
    ..This demonstrates that motor skill learning depends on de novo synthesis of proteins in motor cortex after training...
  2. ncbi request reprint Protein synthesis inhibition blocks consolidation of an acrobatic motor skill
    Andreas R Luft
    Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, 72076 Tubingen, Germany
    Learn Mem 11:379-82. 2004
    ..In overtrained animals, comparable injections of CHX had no effect on rotarod performance. These findings suggest that consolidation of motor skills requires protein synthesis...
  3. ncbi request reprint Transcranial magnetic stimulation in the rat
    A R Luft
    Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA
    Exp Brain Res 140:112-21. 2001
    ..Latency differences between CES and TMS point to a supraspinal origin of the MEPTMS. The two morphologies likely reflect different cortical or subcortical origins of MEPTMS...
  4. ncbi request reprint Frequency and predictors for angiographically improved inflow of contrast medium after carotid angioplasty and stenting
    A R Luft
    Division of Neurosciences, Johns Hopkins University, Baltimore, MD 21287, USA
    Neuroradiology 43:877-83. 2001
    ..Faster appearance of a contrast-medium blush is seen in most cases of carotid angioplasty and stenting and depends on the degree of hemodynamic inflow obstruction relieved by stenting...
  5. ncbi request reprint Lesion location alters brain activation in chronically impaired stroke survivors
    Andreas R Luft
    Department of Neurology, University of Maryland, Baltimore, MD 21287, USA
    Neuroimage 21:924-35. 2004
    ..This finding proposes lesion-specific mechanisms of reorganization. Optimal activation of these distinct networks may require different rehabilitative strategies...
  6. ncbi request reprint Modulation of rodent cortical motor excitability by somatosensory input
    Andreas R Luft
    Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA
    Exp Brain Res 142:562-9. 2002
    ..This increase outlasts the stimulation period and is mediated by supraspinal structures, likely motor cortex. Modulation of motor cortex excitability by somatosensory input may play a role in motor learning and recovery from lesion...
  7. ncbi request reprint Early restitution of electrocorticogram predicts subsequent behavioral recovery from cardiac arrest
    Andreas R Luft
    Department of Neurology, Johns Hopkins University, Baltimore, Maryland, USA
    J Clin Neurophysiol 19:540-6. 2002
    ..05). These findings demonstrate a close temporal and prognostic relationship between electrical and behavioral recovery after hypoxic-ischemic brain injury...
  8. ncbi request reprint Comparing brain activation associated with isolated upper and lower limb movement across corresponding joints
    Andreas R Luft
    Department of Neurology, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Hum Brain Mapp 17:131-40. 2002
    ..05). The data demonstrate that central motor structures contribute differently to isolated elbow and knee movement. Activation during knee movement shows similarities to gait-related activation patterns...
  9. ncbi request reprint Brain activation of lower extremity movement in chronically impaired stroke survivors
    Andreas R Luft
    Division of Brain Injury Outcomes, Department of Neurology, Johns Hopkins University, Baltimore, MD 21218, USA
    Neuroimage 26:184-94. 2005
    ..The data reveal adaptations in networks controlling unilateral paretic knee movement in chronic stroke survivors. These adaptations depend on lesion location and seem to have functional relevance for locomotion...
  10. doi request reprint Motor learning transiently changes cortical somatotopy
    Katiuska Molina-Luna
    Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    Neuroimage 40:1748-54. 2008
    ..The motor memory trace in rats may require changes in motor cortex organization other than those detected by stimulation mapping...
  11. doi request reprint Thin-film epidural microelectrode arrays for somatosensory and motor cortex mapping in rat
    Jonas A Hosp
    Neuroplasticity Laboratory, Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Hoppe Seyler Strasse 3, Tubingen, Germany
    J Neurosci Methods 172:255-62. 2008
    ..Thin-film epidural electrode array technology enables a detailed assessment of sensorimotor cortex physiology in vivo and can be used in longitudinal designs enabling studies of learning and plasticity processes...
  12. ncbi request reprint Comparing motion- and imagery-related activation in the human cerebellum: a functional MRI study
    A R Luft
    Department of Neuroradiology, University of Tubingen, Germany
    Hum Brain Mapp 6:105-13. 1998
    ..For imagery, activation at a comparable location may reflect common functionality, e.g., motor preparation and/or timing. Additional activation in the lateral hemispheres may be related to an imagery-specific function...
  13. ncbi request reprint Characterization of motor skill and instrumental learning time scales in a skilled reaching task in rat
    Manuel M Buitrago
    Neurodegeneration Laboratory, Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    Behav Brain Res 155:249-56. 2004
    ..Learning curves of individual animals were highly variable. These findings confirm in rat that motor skill learning has fast and slow components. No within-session improvement is seen in instrumental learning...
  14. ncbi request reprint Cortical stimulation mapping using epidurally implanted thin-film microelectrode arrays
    Katiuska Molina-Luna
    Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Tubingen, Germany
    J Neurosci Methods 161:118-25. 2007
    ..EMS is specifically suitable for experiments integrating electrophysiology with behavioral and molecular biology techniques...
  15. doi request reprint Motor skill learning depends on protein synthesis in the dorsal striatum after training
    Tobias Wächter
    Department of Neurology, Clinical Neurorehabilitation, Rehabilitation Institute and Technology Center Zurich RITZ, University of Zurich, Frauenklinikstr 26, 8091, Zurich, Switzerland
    Exp Brain Res 200:319-23. 2010
    ..The results support the notion that plasticity in basal ganglia circuits, mediated by protein synthesis, contributes to motor skill learning...
  16. ncbi request reprint Short and long-term motor skill learning in an accelerated rotarod training paradigm
    Manuel M Buitrago
    Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Hoppe Seyler Strasse 3, Tubingen 72076, Germany
    Neurobiol Learn Mem 81:211-6. 2004
    ..Accelerated rotarod training can be regarded a valid paradigm for motor skill learning over short (intrasession, minutes) and long time frames (intersession, days)...
  17. ncbi request reprint Speed of motor re-learning after experimental stroke depends on prior skill
    Maximilian Schubring-Giese
    Neuroplasticity Lab, Department of General Neurology and Hertie Institut for Clinical Brain Research, University of Tubingen, Hoppe Seyler Str 3, 72076, Tubingen, Germany
    Exp Brain Res 181:359-65. 2007
    ..It remains to be tested in humans whether task novelty positively influences rehabilitation therapy...
  18. ncbi request reprint Biphasic cerebral blood flow velocity profile in patients with aneurysmal subarachnoid hemorrhage
    Andreas R Luft
    Division of Neurosciences Critical Care, Johns Hopkins University, Baltimore, MD, USA
    Neurocrit Care 1:455-9. 2004
    ..The significance of this finding remains unclear. This retrospective case-control study was conducted to investigate the characteristics and possible predictors of biphasic CBFV profiles...
  19. ncbi request reprint Coherence-weighted Wiener filtering of somatosensory evoked potentials
    J S Paul
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    IEEE Trans Biomed Eng 48:1484-8. 2001
    ..As such, CWWF should be useful as an important diagnostic tool able to detect minimal changes in the SEP. In an experimental study of cerebral hypoxia, CWWF is shown to be more responsive to detection of injury than WF or TDA...
  20. ncbi request reprint Effects of somatosensory electrical stimulation on neuronal injury after global hypoxia-ischemia
    Manuel M Buitrago
    Dept of Neurology, University of Tubingen, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    Exp Brain Res 158:336-44. 2004
    ..It is concluded that ES during the acute phase of HI does not amplify neuronal damage at 48 h, but may have a protective effect that requires further investigation...
  21. ncbi request reprint Patterns of age-related shrinkage in cerebellum and brainstem observed in vivo using three-dimensional MRI volumetry
    A R Luft
    Department of Neuroradiology, University of Tubingen, Germany
    Cereb Cortex 9:712-21. 1999
    ..In search for a cause of the regional vulnerability, vascular, functional, structural and molecular/genetic factors may be considered...
  22. ncbi request reprint Exercise-mediated locomotor recovery and lower-limb neuroplasticity after stroke
    Larry W Forrester
    Department of Veterans Affairs VA Maryland Health Care System, Research Service, Baltimore, MD, USA
    J Rehabil Res Dev 45:205-20. 2008
    ..Critical needs are to determine the optimal timing and intensities of TM therapy to maximize plasticity and learning effects...
  23. pmc Treadmill exercise activates subcortical neural networks and improves walking after stroke: a randomized controlled trial
    Andreas R Luft
    Department of General Neurology, University of Maryland, School of Medicine, Baltimore, MD, USA
    Stroke 39:3341-50. 2008
    ..This study examines the hypothesis that progressive task-repetitive treadmill exercise (T-EX) improves fitness and gait function in subjects with chronic hemiparetic stroke by inducing adaptations in the brain (plasticity)...
  24. doi request reprint A series of patients with subpial hemorrhage: clinical manifestation, neuroradiological presentation and therapeutic implications
    Patrick Roth
    Dept of General Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Medical School, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    J Neurol 255:1018-22. 2008
    ..Overall, the etiology of subpial hemorrhage remains obscure. Treatment should be symptomatic with particular attention to antiepileptic medication...
  25. ncbi request reprint Modulation of excitability as an early change leading to structural adaptation in the motor cortex
    Mario Manto
    Department of Neurology, Hôpital Erasme ULB, Route de Lennik, Bruxelles, Belgium
    J Neurosci Res 83:177-80. 2006
    ....
  26. pmc Repetitive bilateral arm training and motor cortex activation in chronic stroke: a randomized controlled trial
    Andreas R Luft
    Division of Gerontology, Department of Medicine, University of Maryland School of Medicine, Baltimore 21201, USA
    JAMA 292:1853-61. 2004
    ..Reorganization in central motor networks occurs during early recovery from hemiparetic stroke. In chronic stroke survivors, specific rehabilitation therapy can improve upper extremity function...
  27. pmc Modulation of human corticomotor excitability by somatosensory input
    Alain Kaelin-Lang
    Human Cortical Physiology Section, NINDS, National Institutes of Health, Bethesda, MD 20892, USA
    J Physiol 540:623-33. 2002
    ..The antagonistic effect of LZ supports the hypothesis of GABAergic involvement as an operating mechanism...
  28. ncbi request reprint Modulation of motor cortex excitability by sustained peripheral stimulation: the interaction between the motor cortex and the cerebellum
    Andreas R Luft
    Abt für Allgemeine Neurologie, Hertie Center for Clinical Brain Research, Universitat Tubingen, Tubingen, Germany
    Cerebellum 4:90-6. 2005
    ..It appears that the interpositus nucleus is a main subcortical modulator of the excitability changes occurring in the motor cortex, which may be a substrate of early plasticity effective in motor learning and recovery from lesion...
  29. ncbi request reprint Statistical mapping of speckle autocorrelation for visualization of hyperaemic responses to cortical stimulation
    Joseph S Paul
    Department of Neurology and Neurosurgery, University College, London, UK
    Ann Biomed Eng 34:1107-18. 2006
    ..The SAR images can be a useful tool for visualization of slow wave perfusion dynamics during cortical stimulation...
  30. ncbi request reprint Early adaptations in somatosensory cortex after focal ischemic injury to motor cortex
    Joseph S Paul
    Division of Bioengineering, National University of Singapore, Singapore
    Exp Brain Res 168:178-85. 2006
    ..These results indicate S1 hyperexcitability after M1 injury. Whether these adaptations contribute to functional deficits or play a role in recovery, remains to be determined...
  31. ncbi request reprint Stages of motor skill learning
    Andreas R Luft
    Abteilung Allgemeine Neurologie, Hertie Institut für Klinische Hirnforschung, Universitat Tubingen, Germany
    Mol Neurobiol 32:205-16. 2005
    ..Evidence for stages in motor skill learning is provided by experiments using behavioral, electrophysiological, functional imaging, and cellular/molecular methods...
  32. ncbi request reprint Imaging the development of an ischemic core following photochemically induced cortical infarction in rats using Laser Speckle Contrast Analysis (LASCA)
    Joseph S Paul
    Department of Experimental and Clinical Epilepsy, Institute of Neurology, University College, London, UK
    Neuroimage 29:38-45. 2006
    ..004) during the time interval between the induction of ischemia and the time point of peak flow in the penumbral region...