U Ludewig

Summary

Country: Germany

Publications

  1. ncbi request reprint Uniport of NH4+ by the root hair plasma membrane ammonium transporter LeAMT1;1
    Uwe Ludewig
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, Tubingen, Germany
    J Biol Chem 277:13548-55. 2002
  2. ncbi request reprint Homo- and hetero-oligomerization of ammonium transporter-1 NH4 uniporters
    Uwe Ludewig
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    J Biol Chem 278:45603-10. 2003
  3. pmc Function of the anion transporter AtCLC-d in the trans-Golgi network
    Jennifer von der Fecht-Bartenbach
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, D 72076 Tubingen, Germany
    Plant J 50:466-74. 2007
  4. doi request reprint Plant plasma membrane water channels conduct the signalling molecule H2O2
    Marek Dynowski
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    Biochem J 414:53-61. 2008
  5. pmc Different transport mechanisms in plant and human AMT/Rh-type ammonium transporters
    Maria Mayer
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, Tubingen, Germany
    J Gen Physiol 127:133-44. 2006
  6. ncbi request reprint Molecular mechanisms of ammonium transport and accumulation in plants
    Uwe Ludewig
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    FEBS Lett 581:2301-8. 2007
  7. pmc Electroneutral ammonium transport by basolateral rhesus B glycoprotein
    Uwe Ludewig
    Pflanzenphysiologie, Zentrum für Molekularbiologie der Pflanzen, Universitat Tubingen, Auf der Morgenstelle 1, D 72076, Germany
    J Physiol 559:751-9. 2004
  8. ncbi request reprint Ion transport versus gas conduction: function of AMT/Rh-type proteins
    U Ludewig
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, D 72076 Tubingen, Germany
    Transfus Clin Biol 13:111-6. 2006
  9. ncbi request reprint UPS1 and UPS2 from Arabidopsis mediate high affinity transport of uracil and 5-fluorouracil
    Anja Schmidt
    Plant Physiology, ZMBP, Auf der Morgenstelle 1, D 72076 Tubingen, Germany
    J Biol Chem 279:44817-24. 2004
  10. pmc Molecular and functional characterization of a family of amino acid transporters from Arabidopsis
    Yan Hua Su
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, 72076 Tubingen, Germany
    Plant Physiol 136:3104-13. 2004

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Uniport of NH4+ by the root hair plasma membrane ammonium transporter LeAMT1;1
    Uwe Ludewig
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, Tubingen, Germany
    J Biol Chem 277:13548-55. 2002
    ..5 and pH 8.5. LeAMT1;1 is concluded to mediate potential-driven NH(4+) uptake and retrieval depending on root membrane potential and NH(4+) concentration gradient...
  2. ncbi request reprint Homo- and hetero-oligomerization of ammonium transporter-1 NH4 uniporters
    Uwe Ludewig
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    J Biol Chem 278:45603-10. 2003
    ..Thus, in yeast, oocytes, and plants, ammonium transporters are able to oligomerize, which may be relevant for regulation of ammonium uptake...
  3. pmc Function of the anion transporter AtCLC-d in the trans-Golgi network
    Jennifer von der Fecht-Bartenbach
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, D 72076 Tubingen, Germany
    Plant J 50:466-74. 2007
    ..The results suggest that the luminal pH in the trans-Golgi network is adjusted by AtCLC-d-mediated transport of a counter anion such as Cl(-) or NO(3)(-)...
  4. doi request reprint Plant plasma membrane water channels conduct the signalling molecule H2O2
    Marek Dynowski
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    Biochem J 414:53-61. 2008
    ..Aquaporins are present in most species and their capacity to facilitate the diffusion of H(2)O(2) may be of physiological significance in many organisms and particularly in communication between different species...
  5. pmc Different transport mechanisms in plant and human AMT/Rh-type ammonium transporters
    Maria Mayer
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, Tubingen, Germany
    J Gen Physiol 127:133-44. 2006
    ..Thus, homologous AMT/Rh-type proteins function in a distinct manner; while LeAMT1;2 carries specifically NH4+, or cotransports NH3/H+, RhCG mediates electroneutral NH3 transport...
  6. ncbi request reprint Molecular mechanisms of ammonium transport and accumulation in plants
    Uwe Ludewig
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    FEBS Lett 581:2301-8. 2007
    ..The biological function of plant ammonium transporters will be discussed and compared to other AMT/Rh proteins...
  7. pmc Electroneutral ammonium transport by basolateral rhesus B glycoprotein
    Uwe Ludewig
    Pflanzenphysiologie, Zentrum für Molekularbiologie der Pflanzen, Universitat Tubingen, Auf der Morgenstelle 1, D 72076, Germany
    J Physiol 559:751-9. 2004
    ..Methylammonium uptake is inhibited by ammonium and this inhibition saturates with a Ki approximately 3 mm. Electric current measurements and intracellular pHi determinations suggest that RhBG acts as an electroneutral NH4+ -H+ exchanger...
  8. ncbi request reprint Ion transport versus gas conduction: function of AMT/Rh-type proteins
    U Ludewig
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, D 72076 Tubingen, Germany
    Transfus Clin Biol 13:111-6. 2006
    ..The functional differences between AMT/Rh transporters are likely to be an evolutionary adaptation to different ammonium and nitrogen requirements in bacteria, plants and animals...
  9. ncbi request reprint UPS1 and UPS2 from Arabidopsis mediate high affinity transport of uracil and 5-fluorouracil
    Anja Schmidt
    Plant Physiology, ZMBP, Auf der Morgenstelle 1, D 72076 Tubingen, Germany
    J Biol Chem 279:44817-24. 2004
    ....
  10. pmc Molecular and functional characterization of a family of amino acid transporters from Arabidopsis
    Yan Hua Su
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, 72076 Tubingen, Germany
    Plant Physiol 136:3104-13. 2004
    ..CAT2 is localized to the tonoplast in transformed Arabidopsis protoplasts and thus may encode the long-sought vacuolar amino acid transporter...
  11. ncbi request reprint Role of AMT1;1 in NH4+ acquisition in Arabidopsis thaliana
    M Mayer
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    Plant Biol (Stuttg) 8:522-8. 2006
    ....
  12. pmc Rhesus factors and ammonium: a function in efflux?
    U Ludewig
    Zentrum für Molekularbiologie der Pflanzen, Eberhard Karls Universitat, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    Genome Biol 2:REVIEWS1010. 2001
    ..Completion of fungal, plant and human genomes paved the way to the identification of erythrocytic rhesus proteins and their kidney homologs as ammonium transporters...
  13. doi request reprint Channel-like NH3 flux by ammonium transporter AtAMT2
    Benjamin Neuhäuser
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Tubingen, Germany
    FEBS Lett 583:2833-8. 2009
    ..This transport mechanism may apply to other plant ammonium transporters and explains the different capacities of AMTs to accumulate ammonium in the plant cell...
  14. pmc Overexpression of GLUTAMINE DUMPER1 leads to hypersecretion of glutamine from Hydathodes of Arabidopsis leaves
    Guillaume Pilot
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, D 72076 Germany
    Plant Cell 16:1827-40. 2004
    ..Selective secretion of Gln by the leaves may be explained by an enhanced release of this amino acid from cells. GDU1 study may help to shed light on the secretory mechanisms for amino acids in plants...
  15. pmc Regulation of NH4+ transport by essential cross talk between AMT monomers through the carboxyl tails
    Benjamin Neuhäuser
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, D 72076 Tuebingen, Germany
    Plant Physiol 143:1651-9. 2007
    ..This regulatory mechanism for rapid and efficient inactivation of NH4+ transporters may apply to several AMT members to prevent excess influx of cytotoxic ammonium...
  16. pmc Ammonium ion transport by the AMT/Rh homologue LeAMT1;1
    Maria Mayer
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    Biochem J 396:431-7. 2006
    ..Similarly, NH4+ (or H+/NH3) was transported, but NH3 conduction was excluded. It is concluded that related proteins and a similar molecular architecture can apparently support contrasting transport mechanisms...
  17. doi request reprint CLC-b-mediated NO-3/H+ exchange across the tonoplast of Arabidopsis vacuoles
    Jenny von der Fecht-Bartenbach
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, D 72076 Tubingen, Germany
    Plant Cell Physiol 51:960-8. 2010
    ..Both lines grew as the wild type in various conditions. The total chloride and nitrate content was identical in clcb lines and the wild type, potentially suggesting that mutants were able to compensate the loss of CLC-b...
  18. ncbi request reprint Conservation of amino acid transporters in fungi, plants and animals
    Daniel Wipf
    ZMBP, Plant Physiology, Auf der Morgenstelle 1, Eberhard Karls Universitat Tubingen, D 72076, Tubingen, Germany
    Trends Biochem Sci 27:139-47. 2002
    ..When used in combination with phylogenetic analyses, functional comparison might aid our prediction of physiological functions for related but uncharacterized open reading frames...
  19. pmc A novel superfamily of transporters for allantoin and other oxo derivatives of nitrogen heterocyclic compounds in Arabidopsis
    Marcelo Desimone
    Plant Physiology, Zentrum für Molekularbiologie der Pflanzen, Auf der Morgenstelle 1, D 72076 Tubingen, Germany
    Plant Cell 14:847-56. 2002
    ..In plants, AtUPS1 gene expression was dependent on the nitrogen source. Therefore, AtUPS1 presumably is involved in the uptake of allantoin and other purine degradation products when primary sources are limiting...
  20. ncbi request reprint Low and high affinity amino acid H+-cotransporters for cellular import of neutral and charged amino acids
    Wolf N Fischer
    Plant Physiology, Zentrum für Molekularbiologie der Pflanzen, Tubingen, Germany
    Plant J 29:717-31. 2002
    ..Thus the actual apoplasmic concentration of amino acids and the pH will determine what is transported in vivo, i.e. major amino acids such as glutamine, asparagine, and glutamate will be mobilized preferentially...
  21. doi request reprint Molecular determinants of ammonia and urea conductance in plant aquaporin homologs
    Marek Dynowski
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    FEBS Lett 582:2458-62. 2008
    ..TIP-like mutants conducted urea but not NH(3), and a residue without direct contact to the pore lumen was critical for conduction in the mutants...
  22. ncbi request reprint Visualization of arginine influx into plant cells using a specific FRET-sensor
    Martin Bogner
    Zentrum für Molekularbiologie der Pflanzen, Pflanzenphysiologie, Universitat Tubingen, Auf der Morgenstelle 1, 72076 Tubingen, Germany
    J Fluoresc 17:350-60. 2007
    ..The analysis suggests that fluorescent amino acid sensors may be versatile tools for studying the in vivo dynamics of metabolism and compartmentalization in plants...
  23. pmc Urea transport by nitrogen-regulated tonoplast intrinsic proteins in Arabidopsis
    Lai Hua Liu
    Institut für Pflanzenernährung, Universitat Hohenheim, D 70593 Stuttgart, Germany
    Plant Physiol 133:1220-8. 2003
    ..Thus, in addition to their role as water channels, TIP transporters may play a role in equilibrating urea concentrations between different cellular compartments...
  24. pmc Tonoplast intrinsic proteins AtTIP2;1 and AtTIP2;3 facilitate NH3 transport into the vacuole
    Dominique Loque
    Institut für Pflanzenernährung, Universitat Hohenheim, D 70593 Stuttgart, Germany
    Plant Physiol 137:671-80. 2005
    ..This study shows that AtTIP2;1 and AtTIP2;3 can mediate the extracytosolic transport of methyl-NH2 and NH3 across the tonoplast membrane and may thus participate in vacuolar ammonium compartmentation...
  25. ncbi request reprint Functional and physiological evidence for a rhesus-type ammonia transporter in Nitrosomonas europaea
    Kerstin Weidinger
    Lehrstuhl fur Mikrobiologie, Universitat Bayreuth, Bayreuth, Germany
    FEMS Microbiol Lett 273:260-7. 2007
    ..The results suggest that Rh1 equilibrates the uncharged substrate species. A low pH value in the periplasmic space during ammonia oxidation seems to be responsible for the ammonium accumulation functioning as an acid NH(4) (+) trap...
  26. ncbi request reprint ZmYS1 functions as a proton-coupled symporter for phytosiderophore- and nicotianamine-chelated metals
    Gabriel Schaaf
    Institut für Pflanzenernährung, Universitat Hohenheim, D 70593 Stuttgart, Germany
    J Biol Chem 279:9091-6. 2004
    ..These biochemical properties indicate a novel role of YS1 transporters for heavy metal homeostasis in plants...
  27. pmc The Arabidopsis major intrinsic protein NIP5;1 is essential for efficient boron uptake and plant development under boron limitation
    Junpei Takano
    Biotechnology Research Center, University of Tokyo, Yayoi, Bunkyo ku, Tokyo 113 8657, Japan
    Plant Cell 18:1498-509. 2006
    ..These results identify NIP5;1 as a major plasma membrane boric acid channel crucial for the B uptake required for plant growth and development under B limitation...
  28. pmc AtDUR3 encodes a new type of high-affinity urea/H+ symporter in Arabidopsis
    Lai Hua Liu
    Institut für Pflanzenernährung, Universitat Hohenheim, D 70593 Stuttgart, Germany
    Plant Cell 15:790-800. 2003
    ..AtDUR3 was expressed in shoots and roots and upregulated during early germination and under nitrogen deficiency in roots. We propose a role of AtDUR3 in urea uptake by plant cells at low external urea concentrations...
  29. ncbi request reprint A putative function for the arabidopsis Fe-Phytosiderophore transporter homolog AtYSL2 in Fe and Zn homeostasis
    Gabriel Schaaf
    Institut für Pflanzenernährung, Universitat Hohenheim, D 70593 Stuttgart, Germany
    Plant Cell Physiol 46:762-74. 2005
    ..Taken together, our investigations support an involvement of AtYSL2 in Fe and Zn homeostasis, although functionality or substrate specificity are likely to differ between AtYSL2 and ZmYS1...