Claudia Lengerke

Summary

Country: Germany

Publications

  1. ncbi Autologous blood cell therapies from pluripotent stem cells
    Claudia Lengerke
    Division of Hematology and Oncology, University of Tuebingen Medical Center II, 72076 Tuebingen, Germany
    Blood Rev 24:27-37. 2010
  2. ncbi Caudal genes in blood development and leukemia
    Claudia Lengerke
    University of Tübingen Medical Center Hematology and Oncology, Tubingen, Germany
    Ann N Y Acad Sci 1266:47-54. 2012
  3. ncbi Hematopoietic development from human induced pluripotent stem cells
    Claudia Lengerke
    Division of Hematology and Oncology, University of Tuebingen Medical Center II, Tuebingen, Germany
    Ann N Y Acad Sci 1176:219-27. 2009
  4. ncbi Interactions between Cdx genes and retinoic acid modulate early cardiogenesis
    Claudia Lengerke
    Department of Hematology and Oncology, University of Tuebingen Medical Center II, Tuebingen, Germany
    Dev Biol 354:134-42. 2011
  5. ncbi Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma
    Claudia Lengerke
    University of Tuebingen Medical Center II, Otfried Mueller Strasse 10, 72076 Tuebingen, Germany
    BMC Cancer 11:42. 2011
  6. ncbi Disease models from pluripotent stem cells
    Claudia Lengerke
    Division of Hematology and Oncology, University of Tuebingen Medical Center II, Tuebingen, Germany
    Ann N Y Acad Sci 1176:191-6. 2009
  7. ncbi SOX2 amplification is a common event in squamous cell carcinomas of different organ sites
    Sebastian Maier
    Institute of Pathology, Comprehensive Cancer Center, University Hospital of Tuebingen, 72076 Tuebingen, Germany
    Hum Pathol 42:1078-88. 2011
  8. ncbi Improved detection of splenosis in patients with haematological disorders: the role of combined transmission-emission tomography
    Marius Horger
    Department of Diagnostic Radiology, Eberhard Karls Universitat, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Eur J Nucl Med Mol Imaging 30:316-9. 2003
  9. ncbi Cytomegalovirus pneumonia after stem cell transplantation: correlation of CT findings with clinical outcome in 30 patients
    Marius S Horger
    Department of Diagnostic Radiology, Eberhard Karls University, Hoppe Seyler Strasse 3, Tuebingen 72076, Germany
    AJR Am J Roentgenol 187:W636-43. 2006
  10. ncbi Significance of the "halo" sign for progression and regression of nodular pulmonary amyloidosis: radiographic-pathological correlation (2005:6b)
    Marius Horger
    Department of Diagnostic Radiology, Eberhard Karls University, Tubingen, Germany
    Eur Radiol 15:2037-40. 2005

Collaborators

Detail Information

Publications17

  1. ncbi Autologous blood cell therapies from pluripotent stem cells
    Claudia Lengerke
    Division of Hematology and Oncology, University of Tuebingen Medical Center II, 72076 Tuebingen, Germany
    Blood Rev 24:27-37. 2010
    ....
  2. ncbi Caudal genes in blood development and leukemia
    Claudia Lengerke
    University of Tübingen Medical Center Hematology and Oncology, Tubingen, Germany
    Ann N Y Acad Sci 1266:47-54. 2012
    ..Here, we will review the role of Cdx genes during hematopoietic development by comparing effects in zebrafish and mice and discuss their participation in malignant blood diseases...
  3. ncbi Hematopoietic development from human induced pluripotent stem cells
    Claudia Lengerke
    Division of Hematology and Oncology, University of Tuebingen Medical Center II, Tuebingen, Germany
    Ann N Y Acad Sci 1176:219-27. 2009
    ....
  4. ncbi Interactions between Cdx genes and retinoic acid modulate early cardiogenesis
    Claudia Lengerke
    Department of Hematology and Oncology, University of Tuebingen Medical Center II, Tuebingen, Germany
    Dev Biol 354:134-42. 2011
    ..Together, our data suggest that cdx proteins affect cardiogenesis by regulating the formation of cardiogenic mesoderm and together with the RA pathway control the early development of cardiac precursor cells...
  5. ncbi Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma
    Claudia Lengerke
    University of Tuebingen Medical Center II, Otfried Mueller Strasse 10, 72076 Tuebingen, Germany
    BMC Cancer 11:42. 2011
    ..In breast cancer, SOX2 expression was reported as a feature of basal-like tumors. In this study, we assessed SOX2 expression in 95 primary tumors of postmenopausal breast cancer patients...
  6. ncbi Disease models from pluripotent stem cells
    Claudia Lengerke
    Division of Hematology and Oncology, University of Tuebingen Medical Center II, Tuebingen, Germany
    Ann N Y Acad Sci 1176:191-6. 2009
    ....
  7. ncbi SOX2 amplification is a common event in squamous cell carcinomas of different organ sites
    Sebastian Maier
    Institute of Pathology, Comprehensive Cancer Center, University Hospital of Tuebingen, 72076 Tuebingen, Germany
    Hum Pathol 42:1078-88. 2011
    ..We conclude that SOX2 amplification and consequent SOX2 protein overexpression may represent important mechanisms of tumor initiation and progression in a considerable subset of squamous cell carcinomas...
  8. ncbi Improved detection of splenosis in patients with haematological disorders: the role of combined transmission-emission tomography
    Marius Horger
    Department of Diagnostic Radiology, Eberhard Karls Universitat, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Eur J Nucl Med Mol Imaging 30:316-9. 2003
    ..Diagnostic relevance was highest for intrahepatic, intrapulmonary or pleural splenic implants. It is concluded that TET allows exact localisation of heterotopic splenic tissue in patients with suspected splenosis...
  9. ncbi Cytomegalovirus pneumonia after stem cell transplantation: correlation of CT findings with clinical outcome in 30 patients
    Marius S Horger
    Department of Diagnostic Radiology, Eberhard Karls University, Hoppe Seyler Strasse 3, Tuebingen 72076, Germany
    AJR Am J Roentgenol 187:W636-43. 2006
    ..Also, a change in the CT morphology of pulmonary lesions toward diffuse ground-glass opacity seems to correlate with an unfavorable disease course...
  10. ncbi Significance of the "halo" sign for progression and regression of nodular pulmonary amyloidosis: radiographic-pathological correlation (2005:6b)
    Marius Horger
    Department of Diagnostic Radiology, Eberhard Karls University, Tubingen, Germany
    Eur Radiol 15:2037-40. 2005
    ..In our case, this sign had a high prediction for growth kinetics and response to therapy of pulmonary amyloid...
  11. ncbi Initial CT manifestations of invasive pulmonary aspergillosis in 45 non-HIV immunocompromised patients: association with patient outcome?
    Marius Horger
    Department of Diagnostic Radiology, Eberhard Karls University, Hoppe Seyler Str 3, 72076 Tubingen, Germany
    Eur J Radiol 55:437-44. 2005
    ....
  12. ncbi SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer
    Theresia Wilbertz
    Institute of Pathology, Comprehensive Cancer Center, University Hospital Tuebingen, Tuebingen, Germany
    Mod Pathol 24:944-53. 2011
    ..In conclusion, SOX2 amplification and upregulation are frequent events in squamous cell carcinomas of the lung and are associated with indicators of favorable prognosis...
  13. ncbi Aberrant expression of the homeobox gene CDX2 in pediatric acute lymphoblastic leukemia
    Tamara Riedt
    Department of Hematology Oncology, University of Tuebingen Medical Center II, Tuebingen, Germany
    Blood 113:4049-51. 2009
    ..Thus, CDX2 expression levels may serve as a marker for adverse prognosis in pediatric ALL...
  14. ncbi Patterning definitive hematopoietic stem cells from embryonic stem cells
    Claudia Lengerke
    Department of Hematology and Oncology, University Medical Center II, Tuebingen, Germany
    Exp Hematol 33:971-9. 2005
    ....
  15. ncbi Zebrafish xenografts as a tool for in vivo studies on human cancer
    Martina Konantz
    Department of Hematology and Oncology, University of Tübingen Medical Center II, Tubingen, Germany
    Ann N Y Acad Sci 1266:124-37. 2012
    ..Here, we summarize current data on xenotransplantation of human cells into zebrafish, highlighting the advantages and limitations of this model in comparison to classical murine models of xenotransplantation...
  16. ncbi Monitoring the glioma tropism of bone marrow-derived progenitor cells by 2-photon laser scanning microscopy and positron emission tomography
    Kathy Hasenbach
    Department of General Neurology, University Hospital Tubingen, Tubingen, Germany
    Neuro Oncol 14:471-81. 2012
    ..Moreover, the PET reporter-based imaging technique will allow noninvasive monitoring of cell fate in future cell-based therapeutic antiglioma approaches...
  17. ncbi Patient-specific pluripotent stem cells: promises and challenges
    Rouven Müller
    Laboratory for Developmental Biology, Department of Hematology and Oncology, University of Tübingen Medical Center II, Tubingen, Germany
    Nat Rev Endocrinol 5:195-203. 2009
    ..This Review critically analyzes the currently available methods for the generation of pluripotent stem cells, and discusses prospects for their clinical use...