Christoph Bottcher

Summary

Affiliation: Leibniz Institute of Plant Biochemistry
Country: Germany

Publications

  1. doi request reprint Analysis of phenolic choline esters from seeds of Arabidopsis thaliana and Brassica napus by capillary liquid chromatography/electrospray- tandem mass spectrometry
    Christoph Bottcher
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, Weinberg 3, 06120 Halle Saale, Germany
    J Mass Spectrom 44:466-76. 2009
  2. pmc Reprogramming the phenylpropanoid metabolism in seeds of oilseed rape by suppressing the orthologs of reduced epidermal fluorescence1
    Juliane Mittasch
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, D 06120 Halle, Germany
    Plant Physiol 161:1656-69. 2013
  3. pmc Overexpression of sinapine esterase BnSCE3 in oilseed rape seeds triggers global changes in seed metabolism
    Kathleen Clauss
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, D 06120 Halle, Germany
    Plant Physiol 155:1127-45. 2011
  4. doi request reprint Phenylpropanoid polyamine conjugate biosynthesis in Arabidopsis thaliana flower buds
    Christin Fellenberg
    Department of Plant Secondary Metabolism, Leibniz Institute of Plant Biochemistry, Weinberg 3, D 06120 Halle Saale, Germany
    Phytochemistry 70:1392-400. 2009
  5. pmc Metabolome analysis of biosynthetic mutants reveals a diversity of metabolic changes and allows identification of a large number of new compounds in Arabidopsis
    Christoph Bottcher
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, 06120 Halle Saale, Germany
    Plant Physiol 147:2107-20. 2008
  6. doi request reprint An UPLC-MS/MS method for the simultaneous identification and quantitation of cell wall phenolics in Brassica napus seeds
    Andrej Frolov
    Department of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    J Agric Food Chem 61:1219-27. 2013
  7. doi request reprint The role of UDP-glucose:hydroxycinnamate glucosyltransferases in phenylpropanoid metabolism and the response to UV-B radiation in Arabidopsis thaliana
    Dirk Meissner
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    Planta 228:663-74. 2008
  8. doi request reprint Crosstalk between abiotic ultraviolet-B stress and biotic (flg22) stress signalling in Arabidopsis prevents flavonol accumulation in favor of pathogen defence compound production
    Dirk Schenke
    Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, 06120 Halle Saale, Germany
    Plant Cell Environ 34:1849-64. 2011
  9. pmc The multifunctional enzyme CYP71B15 (PHYTOALEXIN DEFICIENT3) converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana
    Christoph Bottcher
    Department of Stress, Leibniz Institute of Plant Biochemistry, 06120 Halle Saale, Germany
    Plant Cell 21:1830-45. 2009
  10. ncbi request reprint The transition metal chelator nicotianamine is synthesized by filamentous fungi
    Aleksandra Trampczynska
    Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    FEBS Lett 580:3173-8. 2006

Collaborators

Detail Information

Publications16

  1. doi request reprint Analysis of phenolic choline esters from seeds of Arabidopsis thaliana and Brassica napus by capillary liquid chromatography/electrospray- tandem mass spectrometry
    Christoph Bottcher
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, Weinberg 3, 06120 Halle Saale, Germany
    J Mass Spectrom 44:466-76. 2009
    ..Therefore, LC/ESI-MS/MS represents a valuable tool for comprehensive qualitative and quantitative analysis of this compound class...
  2. pmc Reprogramming the phenylpropanoid metabolism in seeds of oilseed rape by suppressing the orthologs of reduced epidermal fluorescence1
    Juliane Mittasch
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, D 06120 Halle, Germany
    Plant Physiol 161:1656-69. 2013
    ..Mapping of the changed metabolites onto the phenylpropanoid metabolic network revealed partial redirection of metabolic sequences as a major impact of BnREF1 suppression...
  3. pmc Overexpression of sinapine esterase BnSCE3 in oilseed rape seeds triggers global changes in seed metabolism
    Kathleen Clauss
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, D 06120 Halle, Germany
    Plant Physiol 155:1127-45. 2011
    ..Mapping of these changes onto metabolic pathways revealed global effects of the transgenic BnSCE3 expression on seed metabolism...
  4. doi request reprint Phenylpropanoid polyamine conjugate biosynthesis in Arabidopsis thaliana flower buds
    Christin Fellenberg
    Department of Plant Secondary Metabolism, Leibniz Institute of Plant Biochemistry, Weinberg 3, D 06120 Halle Saale, Germany
    Phytochemistry 70:1392-400. 2009
    ..The implication of these findings for spermidine conjugate biosynthesis in flower buds of A. thaliana is discussed...
  5. pmc Metabolome analysis of biosynthetic mutants reveals a diversity of metabolic changes and allows identification of a large number of new compounds in Arabidopsis
    Christoph Bottcher
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, 06120 Halle Saale, Germany
    Plant Physiol 147:2107-20. 2008
    ..However, sinapoylcholine is not the only accumulating end product. Instead, we observed specific and sophisticated changes in the complex pattern of sinapate derivatives...
  6. doi request reprint An UPLC-MS/MS method for the simultaneous identification and quantitation of cell wall phenolics in Brassica napus seeds
    Andrej Frolov
    Department of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    J Agric Food Chem 61:1219-27. 2013
    ..This approach was successfully applied to the analysis of cell wall phenolic patterns in different B. napus cultivars and proved to be suitable for marker compound search as well as assay development...
  7. doi request reprint The role of UDP-glucose:hydroxycinnamate glucosyltransferases in phenylpropanoid metabolism and the response to UV-B radiation in Arabidopsis thaliana
    Dirk Meissner
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    Planta 228:663-74. 2008
    ..Exposure of plants to enhanced UV-B radiation induced the UGT84A-encoding genes and led to a transient increase in sinapoylglucose and sinapoylmalate concentrations...
  8. doi request reprint Crosstalk between abiotic ultraviolet-B stress and biotic (flg22) stress signalling in Arabidopsis prevents flavonol accumulation in favor of pathogen defence compound production
    Dirk Schenke
    Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, 06120 Halle Saale, Germany
    Plant Cell Environ 34:1849-64. 2011
    ....
  9. pmc The multifunctional enzyme CYP71B15 (PHYTOALEXIN DEFICIENT3) converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana
    Christoph Bottcher
    Department of Stress, Leibniz Institute of Plant Biochemistry, 06120 Halle Saale, Germany
    Plant Cell 21:1830-45. 2009
    ..In conclusion, in the camalexin biosynthetic pathway, IAN is derivatized to the intermediate Cys(IAN), which serves as substrate of the multifunctional cytochrome P450 enzyme CYP71B15...
  10. ncbi request reprint The transition metal chelator nicotianamine is synthesized by filamentous fungi
    Aleksandra Trampczynska
    Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    FEBS Lett 580:3173-8. 2006
    ..These findings demonstrate that nicotianamine is more widespread in nature than anticipated and provide further evidence for a function of nicotianamine as a cytosolic chelator of Zn2+ ions...
  11. pmc CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets
    Carsten Kuhl
    Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    Anal Chem 84:283-9. 2012
    ..We demonstrate the utility of CAMERA in two different, easily adoptable plant metabolomics experiments, where the application of CAMERA drastically reduced the amount of manual analysis...
  12. ncbi request reprint Analysis of fungal cyclopentenone derivatives from Hygrophorus spp. by liquid chromatography/electrospray-tandem mass spectrometry
    Tilo Lübken
    Leibniz Institute of Plant Biochemistry, Weinberg 3, D 06120 Halle Saale, Germany
    J Mass Spectrom 41:361-71. 2006
    ..The elemental composition of the fragment ions was determined by ESI-QqTOF measurements. Thus, in case of the negative ion CID mass spectra an unusual loss of CO2 from the deprotonated molecular ions could be observed...
  13. pmc Highly sensitive feature detection for high resolution LC/MS
    Ralf Tautenhahn
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, Halle, Germany
    BMC Bioinformatics 9:504. 2008
    ..For the subsequent analysis of complex samples such as plant extracts, which may contain hundreds of compounds, corresponding to thousands of features -- a reliable feature detection is mandatory...
  14. doi request reprint Tapetum-specific location of a cation-dependent O-methyltransferase in Arabidopsis thaliana
    Christin Fellenberg
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, Weinberg 3, D 06120 Halle Saale, Germany
    Plant J 56:132-45. 2008
    ..The in vitro substrate specificity and the in vivo RNAi-mediated suppression data of the corresponding gene suggest a role of this cation-dependent CCoAOMT-like protein in the stamen/pollen development of A. thaliana...
  15. ncbi request reprint Evaluation of matrix effects in metabolite profiling based on capillary liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry
    Christoph Bottcher
    Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    Anal Chem 79:1507-13. 2007
    ..In conclusion, employing LC-coupled ESI-QTOF-MS for metabolomics studies is feasible yet rigorous validation is necessary...
  16. pmc Phytochelatin synthesis is essential for the detoxification of excess zinc and contributes significantly to the accumulation of zinc
    Pierre Tennstedt
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, 06120 Halle Saale, Germany
    Plant Physiol 149:938-48. 2009
    ..This function might also help explain the mysterious occurrence of PC synthase genes throughout the plant kingdom and in a wide range of other organisms...