Christoph Bottcher

Summary

Affiliation: Leibniz Institute of Plant Biochemistry
Country: Germany

Publications

  1. ncbi Analysis of phenolic choline esters from seeds of Arabidopsis thaliana and Brassica napus by capillary liquid chromatography/electrospray- tandem mass spectrometry
    Christoph Bottcher
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, Weinberg 3, 06120 Halle Saale, Germany
    J Mass Spectrom 44:466-76. 2009
  2. ncbi Overexpression of sinapine esterase BnSCE3 in oilseed rape seeds triggers global changes in seed metabolism
    Kathleen Clauss
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, D 06120 Halle, Germany
    Plant Physiol 155:1127-45. 2011
  3. ncbi Metabolome analysis of biosynthetic mutants reveals a diversity of metabolic changes and allows identification of a large number of new compounds in Arabidopsis
    Christoph Bottcher
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, 06120 Halle Saale, Germany
    Plant Physiol 147:2107-20. 2008
  4. ncbi Phenylpropanoid polyamine conjugate biosynthesis in Arabidopsis thaliana flower buds
    Christin Fellenberg
    Department of Plant Secondary Metabolism, Leibniz Institute of Plant Biochemistry, Weinberg 3, D 06120 Halle Saale, Germany
    Phytochemistry 70:1392-400. 2009
  5. ncbi The role of UDP-glucose:hydroxycinnamate glucosyltransferases in phenylpropanoid metabolism and the response to UV-B radiation in Arabidopsis thaliana
    Dirk Meissner
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    Planta 228:663-74. 2008
  6. ncbi Crosstalk between abiotic ultraviolet-B stress and biotic (flg22) stress signalling in Arabidopsis prevents flavonol accumulation in favor of pathogen defence compound production
    Dirk Schenke
    Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, 06120 Halle Saale, Germany
    Plant Cell Environ 34:1849-64. 2011
  7. ncbi The multifunctional enzyme CYP71B15 (PHYTOALEXIN DEFICIENT3) converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana
    Christoph Bottcher
    Department of Stress, Leibniz Institute of Plant Biochemistry, 06120 Halle Saale, Germany
    Plant Cell 21:1830-45. 2009
  8. ncbi CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets
    Carsten Kuhl
    Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    Anal Chem 84:283-9. 2012
  9. ncbi Analysis of fungal cyclopentenone derivatives from Hygrophorus spp. by liquid chromatography/electrospray-tandem mass spectrometry
    Tilo Lübken
    Leibniz Institute of Plant Biochemistry, Weinberg 3, D 06120 Halle Saale, Germany
    J Mass Spectrom 41:361-71. 2006
  10. ncbi Highly sensitive feature detection for high resolution LC/MS
    Ralf Tautenhahn
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, Halle, Germany
    BMC Bioinformatics 9:504. 2008

Collaborators

Detail Information

Publications13

  1. ncbi Analysis of phenolic choline esters from seeds of Arabidopsis thaliana and Brassica napus by capillary liquid chromatography/electrospray- tandem mass spectrometry
    Christoph Bottcher
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, Weinberg 3, 06120 Halle Saale, Germany
    J Mass Spectrom 44:466-76. 2009
    ..Therefore, LC/ESI-MS/MS represents a valuable tool for comprehensive qualitative and quantitative analysis of this compound class...
  2. ncbi Overexpression of sinapine esterase BnSCE3 in oilseed rape seeds triggers global changes in seed metabolism
    Kathleen Clauss
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, D 06120 Halle, Germany
    Plant Physiol 155:1127-45. 2011
    ..Mapping of these changes onto metabolic pathways revealed global effects of the transgenic BnSCE3 expression on seed metabolism...
  3. ncbi Metabolome analysis of biosynthetic mutants reveals a diversity of metabolic changes and allows identification of a large number of new compounds in Arabidopsis
    Christoph Bottcher
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, 06120 Halle Saale, Germany
    Plant Physiol 147:2107-20. 2008
    ..However, sinapoylcholine is not the only accumulating end product. Instead, we observed specific and sophisticated changes in the complex pattern of sinapate derivatives...
  4. ncbi Phenylpropanoid polyamine conjugate biosynthesis in Arabidopsis thaliana flower buds
    Christin Fellenberg
    Department of Plant Secondary Metabolism, Leibniz Institute of Plant Biochemistry, Weinberg 3, D 06120 Halle Saale, Germany
    Phytochemistry 70:1392-400. 2009
    ..The implication of these findings for spermidine conjugate biosynthesis in flower buds of A. thaliana is discussed...
  5. ncbi The role of UDP-glucose:hydroxycinnamate glucosyltransferases in phenylpropanoid metabolism and the response to UV-B radiation in Arabidopsis thaliana
    Dirk Meissner
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    Planta 228:663-74. 2008
    ..Exposure of plants to enhanced UV-B radiation induced the UGT84A-encoding genes and led to a transient increase in sinapoylglucose and sinapoylmalate concentrations...
  6. ncbi Crosstalk between abiotic ultraviolet-B stress and biotic (flg22) stress signalling in Arabidopsis prevents flavonol accumulation in favor of pathogen defence compound production
    Dirk Schenke
    Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, 06120 Halle Saale, Germany
    Plant Cell Environ 34:1849-64. 2011
    ....
  7. ncbi The multifunctional enzyme CYP71B15 (PHYTOALEXIN DEFICIENT3) converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana
    Christoph Bottcher
    Department of Stress, Leibniz Institute of Plant Biochemistry, 06120 Halle Saale, Germany
    Plant Cell 21:1830-45. 2009
    ..In conclusion, in the camalexin biosynthetic pathway, IAN is derivatized to the intermediate Cys(IAN), which serves as substrate of the multifunctional cytochrome P450 enzyme CYP71B15...
  8. ncbi CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets
    Carsten Kuhl
    Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    Anal Chem 84:283-9. 2012
    ..We demonstrate the utility of CAMERA in two different, easily adoptable plant metabolomics experiments, where the application of CAMERA drastically reduced the amount of manual analysis...
  9. ncbi Analysis of fungal cyclopentenone derivatives from Hygrophorus spp. by liquid chromatography/electrospray-tandem mass spectrometry
    Tilo Lübken
    Leibniz Institute of Plant Biochemistry, Weinberg 3, D 06120 Halle Saale, Germany
    J Mass Spectrom 41:361-71. 2006
    ..The elemental composition of the fragment ions was determined by ESI-QqTOF measurements. Thus, in case of the negative ion CID mass spectra an unusual loss of CO2 from the deprotonated molecular ions could be observed...
  10. ncbi Highly sensitive feature detection for high resolution LC/MS
    Ralf Tautenhahn
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, Halle, Germany
    BMC Bioinformatics 9:504. 2008
    ..For the subsequent analysis of complex samples such as plant extracts, which may contain hundreds of compounds, corresponding to thousands of features -- a reliable feature detection is mandatory...
  11. ncbi Phytochelatin synthesis is essential for the detoxification of excess zinc and contributes significantly to the accumulation of zinc
    Pierre Tennstedt
    Leibniz Institute of Plant Biochemistry, Department of Stress and Developmental Biology, 06120 Halle Saale, Germany
    Plant Physiol 149:938-48. 2009
    ..This function might also help explain the mysterious occurrence of PC synthase genes throughout the plant kingdom and in a wide range of other organisms...
  12. ncbi Tapetum-specific location of a cation-dependent O-methyltransferase in Arabidopsis thaliana
    Christin Fellenberg
    Department of Secondary Metabolism, Leibniz Institute of Plant Biochemistry, Weinberg 3, D 06120 Halle Saale, Germany
    Plant J 56:132-45. 2008
    ..The in vitro substrate specificity and the in vivo RNAi-mediated suppression data of the corresponding gene suggest a role of this cation-dependent CCoAOMT-like protein in the stamen/pollen development of A. thaliana...
  13. ncbi Evaluation of matrix effects in metabolite profiling based on capillary liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry
    Christoph Bottcher
    Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle Saale, Germany
    Anal Chem 79:1507-13. 2007
    ..In conclusion, employing LC-coupled ESI-QTOF-MS for metabolomics studies is feasible yet rigorous validation is necessary...