Manfred Laucht

Summary

Country: Germany

Publications

  1. ncbi [Dopaminergic polymorphisms and regulatory problems in infancy]
    Katja Becker
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters am Zentralinstitut für Seelische Gesundheit, Mannheim
    Z Kinder Jugendpsychiatr Psychother 35:145-51. 2007
  2. ncbi Novelty seeking involved in mediating the association between the dopamine D4 receptor gene exon III polymorphism and heavy drinking in male adolescents: results from a high-risk community sample
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 61:87-92. 2007
  3. doi Interacting effects of CRHR1 gene and stressful life events on drinking initiation and progression among 19-year-olds
    Brigitte Schmid
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Int J Neuropsychopharmacol 13:703-14. 2010
  4. ncbi Impact of psychosocial adversity on alcohol intake in young adults: moderation by the LL genotype of the serotonin transporter polymorphism
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 66:102-9. 2009
  5. ncbi Impact of age at first drink on vulnerability to alcohol-related problems: testing the marker hypothesis in a prospective study of young adults
    Arlette F Buchmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany
    J Psychiatr Res 43:1205-12. 2009
  6. doi Catechol-O-methyltransferase Val158 Met genotype, parenting practices and adolescent alcohol use: testing the differential susceptibility hypothesis
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Child Psychol Psychiatry 53:351-9. 2012
  7. doi Genetic variation in dopamine pathways differentially associated with smoking progression in adolescence
    Manfred Laucht
    Central Institute of Mental Health, Department of Child and Adolescent Psychiatry and Psychotherapy, P O Box 122120, D 68072 Mannheim, Germany
    J Am Acad Child Adolesc Psychiatry 47:673-81. 2008
  8. doi Temperamental predictors of externalizing problems among boys and girls: a longitudinal study in a high-risk sample from ages 3 months to 15 years
    Martina Pitzer
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Eur Arch Psychiatry Clin Neurosci 259:445-58. 2009
  9. doi The interaction between the dopamine transporter gene and age at onset in relation to tobacco and alcohol use among 19-year-olds
    Brigitte Schmid
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Addict Biol 14:489-99. 2009
  10. doi Drinking against unpleasant emotions: possible outcome of early onset of alcohol use?
    Arlette F Buchmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Alcohol Clin Exp Res 34:1052-7. 2010

Collaborators

Detail Information

Publications56

  1. ncbi [Dopaminergic polymorphisms and regulatory problems in infancy]
    Katja Becker
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters am Zentralinstitut für Seelische Gesundheit, Mannheim
    Z Kinder Jugendpsychiatr Psychother 35:145-51. 2007
    ..We investigated whether or not the severity of the above-mentioned dopaminergic polymorphisms is associated with regulatory disorders in infancy...
  2. ncbi Novelty seeking involved in mediating the association between the dopamine D4 receptor gene exon III polymorphism and heavy drinking in male adolescents: results from a high-risk community sample
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 61:87-92. 2007
    ..The aim of this study was to examine whether allelic variants of the dopamine D4 receptor gene (DRD4) are associated with alcohol use in adolescents and to determine the extent to which these links are mediated by NS...
  3. doi Interacting effects of CRHR1 gene and stressful life events on drinking initiation and progression among 19-year-olds
    Brigitte Schmid
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Int J Neuropsychopharmacol 13:703-14. 2010
    ..These findings extend previous reports by demonstrating that the CRHR1 gene and stressful life events interact to predict both drinking initiation in adolescence and progression of heavy alcohol use in young adulthood...
  4. ncbi Impact of psychosocial adversity on alcohol intake in young adults: moderation by the LL genotype of the serotonin transporter polymorphism
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 66:102-9. 2009
    ..The present study aims to further explore G x E between 5-HTTLPR and exposure to psychosocial adversity on alcohol consumption in a high-risk community sample of young adults...
  5. ncbi Impact of age at first drink on vulnerability to alcohol-related problems: testing the marker hypothesis in a prospective study of young adults
    Arlette F Buchmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany
    J Psychiatr Res 43:1205-12. 2009
    ....
  6. doi Catechol-O-methyltransferase Val158 Met genotype, parenting practices and adolescent alcohol use: testing the differential susceptibility hypothesis
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Child Psychol Psychiatry 53:351-9. 2012
    ..Moreover, the current study examined whether a potential G×E would be consistent with one of two models of gene-environment interplay (genetic vulnerability vs. differential susceptibility)...
  7. doi Genetic variation in dopamine pathways differentially associated with smoking progression in adolescence
    Manfred Laucht
    Central Institute of Mental Health, Department of Child and Adolescent Psychiatry and Psychotherapy, P O Box 122120, D 68072 Mannheim, Germany
    J Am Acad Child Adolesc Psychiatry 47:673-81. 2008
    ..To clarify the nature of the association between dopamine genes and smoking by examining whether genetic variability in components of the dopamine pathway could explain refined phenotypes in adolescent smoking progression...
  8. doi Temperamental predictors of externalizing problems among boys and girls: a longitudinal study in a high-risk sample from ages 3 months to 15 years
    Martina Pitzer
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Eur Arch Psychiatry Clin Neurosci 259:445-58. 2009
    ..Findings are discussed in terms of gender-specific risk factors and possible differential developmental trajectories to subtypes of disruptive behavior...
  9. doi The interaction between the dopamine transporter gene and age at onset in relation to tobacco and alcohol use among 19-year-olds
    Brigitte Schmid
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Addict Biol 14:489-99. 2009
    ..Further studies are required to confirm these findings...
  10. doi Drinking against unpleasant emotions: possible outcome of early onset of alcohol use?
    Arlette F Buchmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Alcohol Clin Exp Res 34:1052-7. 2010
    ..The purpose of this study was to examine whether this effect may be the consequence of a higher susceptibility to develop "drinking to cope" motives among early initiators...
  11. doi Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adults
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Int J Neuropsychopharmacol 12:737-47. 2009
    ..No evidence for GxE was obtained with regard to current stressful life events and trait anxiety. One possible source for the conflicting findings might be attributed to heterogeneity in depression phenotypes and environmental adversity...
  12. doi Negative association between plasma cortisol levels and aggression in a high-risk community sample of adolescents
    Luise Poustka
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
    J Neural Transm 117:621-7. 2010
    ..This result suggests that the association between cortisol levels and aggression in adolescents is mediated rather by impulsivity than by unemotional or psychopathic traits...
  13. doi Evidence for epistasis between the 5-HTTLPR and the dopamine D4 receptor polymorphisms in externalizing behavior among 15-year-olds
    Sarah Hohmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
    J Neural Transm 116:1621-9. 2009
    ..This result suggests an effect of 5-HTTLPR on externalizing behavior in the presence of DRD4 7r but no effect in its absence...
  14. doi BDNF Val 66 Met and 5-HTTLPR genotype moderate the impact of early psychosocial adversity on plasma brain-derived neurotrophic factor and depressive symptoms: a prospective study
    Arlette F Buchmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Germany
    Eur Neuropsychopharmacol 23:902-9. 2013
    ....
  15. doi Maternal stimulation in infancy predicts hypothalamic-pituitary-adrenal axis reactivity in young men
    Brigitte Schmid
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg University, J 5, 68159, Mannheim, Germany
    J Neural Transm 120:1247-57. 2013
    ....
  16. doi Interactive effects of corticotropin-releasing hormone receptor 1 gene and childhood adversity on depressive symptoms in young adults: findings from a longitudinal study
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg University, Mannheim, Germany
    Eur Neuropsychopharmacol 23:358-67. 2013
    ....
  17. pmc Association of PER2 genotype and stressful life events with alcohol drinking in young adults
    Dorothea Blomeyer
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
    PLoS ONE 8:e59136. 2013
    ....
  18. doi Differential susceptibility to environmental influences: the role of early temperament and parenting in the development of externalizing problems
    Martina Pitzer
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, PO Box 12 21 20, 68072 Mannheim, Germany
    Compr Psychiatry 52:650-8. 2011
    ..We investigated the impact of early temperament and parenting and their interactions on externalizing behavior at school age...
  19. doi From regulatory problems in infancy to attention-deficit/hyperactivity disorder in childhood: a moderating role for the dopamine D4 receptor gene?
    Katja Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, Philipps University Marburg, Marburg, Germany
    J Pediatr 156:798-803, 803.e1-803.e2. 2010
    ..To examine whether the dopamine receptor D4 gene (DRD4) exon III VNTR moderates the risk of infants with regulatory disorders for developing attention-deficit/hyperactivity disorder (ADHD) later in childhood...
  20. doi Age at first drink moderates the impact of current stressful life events on drinking behavior in young adults
    Dorothea Blomeyer
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Alcohol Clin Exp Res 35:1142-8. 2011
    ..The present study aimed to extend these findings by examining whether AFD interacted with stressful life events (SLE) and/or with daily hassles regarding the impact on drinking patterns among young adults...
  21. ncbi Temperament in the developmental course: a longitudinal comparison of New York Longitudinal Study-derived dimensions with the Junior Temperament and Character Inventory
    Martina Pitzer
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, P O Box 12 21 20, 68072 Mannheim, Germany
    Compr Psychiatry 48:572-82. 2007
    ....
  22. ncbi Interaction between CRHR1 gene and stressful life events predicts adolescent heavy alcohol use
    Dorothea Blomeyer
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 63:146-51. 2008
    ..The aim of this study was to examine interactions between two haplotype-tagging single nucleotide polymorphisms (SNPs) covering the CRHR1 gene and adverse life events on heavy drinking in adolescents...
  23. doi Interaction of dopamine transporter genotype with prenatal smoke exposure on ADHD symptoms
    Katja Becker
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Pediatr 152:263-9. 2008
    ....
  24. doi The Child Behavior Checklist-Dysregulation Profile predicts substance use, suicidality, and functional impairment: a longitudinal analysis
    Martin Holtmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Child Psychol Psychiatry 52:139-47. 2011
    ..This is the first study outside the US that examines the longitudinal course of the CBCL-DP...
  25. ncbi Moderating role of FKBP5 genotype in the impact of childhood adversity on cortisol stress response during adulthood
    Arlette F Buchmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, J 5, 68159 Mannheim, Germany
    Eur Neuropsychopharmacol 24:837-45. 2014
    ....
  26. doi Quality of early mother-child interaction associated with depressive psychopathology in the offspring: a prospective study from infancy to adulthood
    Brigitte Schmid
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Psychiatr Res 45:1387-94. 2011
    ..The results suggest that the amount of maternally initiated contact behavior in a very early developmental stage may be crucial for children's mental health, regardless of child and maternal responsiveness...
  27. ncbi Concurrent alcohol and tobacco use during early adolescence characterizes a group at risk
    Brigitte Schmid
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, P O Box 122120, D 68072 Mannheim, Germany
    Alcohol Alcohol 42:219-25. 2007
    ..To investigate whether concurrent alcohol and tobacco use during early adolescence characterizes a subgroup that differs from users of one substance only regarding several risk factors for later substance use problems...
  28. ncbi Effect of prenatal exposure to tobacco smoke on inhibitory control: neuroimaging results from a 25-year prospective study
    Nathalie E Holz
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg University, Mannheim, Germany
    JAMA Psychiatry 71:786-96. 2014
    ..Attempts to uncover the effect of prenatal exposure to nicotine on inhibitory control may thus be of high clinical importance...
  29. doi Offspring of parents with an alcohol use disorder prefer higher levels of brain alcohol exposure in experiments involving computer-assisted self-infusion of ethanol (CASE)
    Ulrich S Zimmermann
    Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
    Psychopharmacology (Berl) 202:689-97. 2009
    ..Acute alcohol effects may differ in social drinkers with a positive family history of alcohol use disorders (FHP) compared to FH negative (FHN) controls...
  30. ncbi Low level of response to alcohol as associated with serotonin transporter genotype and high alcohol intake in adolescents
    Anne S Hinckers
    Department of Psychosomatics, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 60:282-7. 2006
    ..To date, all studies of relevant polymorphisms have been carried out in populations in the United States...
  31. doi From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disorders
    Anne Kathrin Wermter
    Department of Child and Adolescent Psychiatry and Psychotherapy, Philipps University of Marburg, Hans Sachs Strasse 6, Marburg, Germany
    Eur Child Adolesc Psychiatry 19:199-210. 2010
    ..In future we need larger, sufficiently powered studies that include a detailed and sophisticated characterization of both phenotype and the environmental risk...
  32. ncbi Impact of pubertal stage at first drink on adult drinking behavior
    Dorothea Blomeyer
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
    Alcohol Clin Exp Res 37:1804-11. 2013
    ..However, the influence of the pubertal phase at alcohol use initiation on subsequent drinking in later life has not been examined so far...
  33. doi Prediction of preadolescent depressive symptoms from child temperament, maternal distress, and gender: results of a prospective, longitudinal study
    Martina Pitzer
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Dev Behav Pediatr 32:18-26. 2011
    ..This study investigates the impact of child temperament and early maternal distress, both of which are known to influence children's emotional development, on preadolescent depression...
  34. ncbi Language development at ten months. Predictive of language outcome and school achievement ten years later?
    Erika Hohm
    Dept of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, P O Box 122120, 68072, Mannheim, Germany
    Eur Child Adolesc Psychiatry 16:149-56. 2007
    ..Language development was followed from infancy to primary school age in order to examine the predictive significance for later language and scholastic outcome...
  35. doi Impact of early parental child-rearing behavior on young adults' cardiometabolic risk profile: a prospective study
    Arlette F Buchmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany
    Psychosom Med 72:156-62. 2010
    ..Moreover, there is evidence suggesting that environmental conditions, such as stress in pre- and postnatal life, may have a sustained impact on an individual's metabolic risk profile...
  36. ncbi Visual exploratory behaviour in infancy and novelty seeking in adolescence: two developmentally specific phenotypes of DRD4?
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    J Child Psychol Psychiatry 47:1143-51. 2006
    ..The present study was designed to investigate the association between visual exploratory behaviour in early infancy, novelty seeking in adolescence, and the dopamine D4 receptor (DRD4) genotype...
  37. ncbi Interacting effects of the dopamine transporter gene and psychosocial adversity on attention-deficit/hyperactivity disorder symptoms among 15-year-olds from a high-risk community sample
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
    Arch Gen Psychiatry 64:585-90. 2007
    ..Recent evidence suggests that gene x environment interactions could explain the inconsistent findings of association studies relating the dopamine transporter (DAT1) gene with attention-deficit/hyperactivity disorder (ADHD)...
  38. doi Mothers' prenatal stress and their children's antisocial outcomes--a moderating role for the Dopamine D4 Receptor (DRD4) gene
    Katrin Zohsel
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim Heidelberg University, Mannheim, Germany
    J Child Psychol Psychiatry 55:69-76. 2014
    ..So far, it is not known whether the DRD4 genotype moderates the effect of prenatal maternal stress on the development of childhood antisocial behavior...
  39. doi Early smoking onset may promise initial pleasurable sensations and later addiction
    Arlette F Buchmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Germany Department of Biostatistics, Central Institute of Mental Health, Germany Department of Psychology, Division of Clinical Psychology, University of Potsdam, Germany
    Addict Biol 18:947-54. 2013
    ..Thus, both the age of first cigarette and the pleasure experienced from the cigarette independently predicted aspects of smoking at age 22. ..
  40. ncbi How gene-stress-behavior interactions can promote adolescent alcohol use: the roles of predrinking allostatic load and childhood behavior disorders
    Ulrich S Zimmermann
    Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, J5, Mannheim, Germany
    Pharmacol Biochem Behav 86:246-62. 2007
    ..They are targets for preventive interventions, which should start as early as possible in subjects at-risk...
  41. ncbi Sequential inhibitory control processes assessed through simultaneous EEG-fMRI
    Sarah Baumeister
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg University, Mannheim, Germany
    Neuroimage 94:349-59. 2014
    ....
  42. ncbi Association of the DRD4 exon III polymorphism with smoking in fifteen-year-olds: a mediating role for novelty seeking?
    Manfred Laucht
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, D 68072 Mannheim, Germany
    J Am Acad Child Adolesc Psychiatry 44:477-84. 2005
    ....
  43. ncbi Late sequelae of low birthweight: mediators of poor school performance at 11 years
    Diana Weindrich
    Central Institute of Mental Health, Mannheim, Germany
    Dev Med Child Neurol 45:463-9. 2003
    ..Parents and pediatricians should be made aware of specific long-term deficits of low birthweight children that may impair school performance, although they may be within a normal curriculum...
  44. doi Drugs as instruments from a developmental child and adolescent psychiatric perspective
    Tobias Banaschewski
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany www zi mannheim de
    Behav Brain Sci 34:312-3. 2011
    ..Early initiation seems to be associated with a reduced ability to use drugs purposely in a temporally stable, non-addictive manner. Prevention strategies should consider social environmental factors and aim to delay age at initiation...
  45. ncbi Association of testosterone and dihydrotestosterone with externalizing behavior in adolescent boys and girls
    Athanasios Maras
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, P O Box 122120, 68072 Mannheim, Germany
    Psychoneuroendocrinology 28:932-40. 2003
    ....
  46. ncbi Father-infant interaction patterns as precursors of children's later externalizing behavior problems: a longitudinal study over 11 years
    Patricia Trautmann-Villalba
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, P O Box 122120, 68072, Mannheim, Germany
    Eur Arch Psychiatry Clin Neurosci 256:344-9. 2006
    ..This study examined the extent to which fathers' and infants' interaction behavior were related to children's externalizing behavior problems at age 8 and 11 years...
  47. doi Simultaneous EEG and fMRI reveals a causally connected subcortical-cortical network during reward anticipation
    Michael M Plichta
    Central Institute of Mental Health, Medical Faculty Mannheim Heidelberg, Department of Psychiatry and Psychotherapy, 68159 Mannheim, Germany
    J Neurosci 33:14526-33. 2013
    ..Collectively, these findings represent a likely neurobiological mechanism mapping a primarily subcortical process, i.e., reward anticipation, onto a cortical signature. ..
  48. ncbi Frontal brain activation in anxious school children
    Lioba Baving
    Central Institute of Mental Health, Germany
    J Child Psychol Psychiatry 43:265-74. 2002
    ..Can this pattern be demonstrated in children of different ages? and 3. Are there gender differences in these patterns similar to those that have been demonstrated in adults? Baseline EEG activity was subjected to power spectral analysis...
  49. ncbi Early mother-infant interaction as a precursor to childhood social withdrawal
    Martin Gerhold
    Central Institute of Mental Health, Department of Child and Adolescent Psychiatry and Psychotherapy, Mannheim, Germany
    Child Psychiatry Hum Dev 32:277-93. 2002
    ..Among the risks only biological risks significantly contribute to later child outcome. These results suggest that a dysfunctional interaction pattern between mother and infant may be a precursor of childhood social withdrawal...
  50. ncbi [Maternal smoking during pregnancy: risk factor for ADHD in the offspring?]
    Manfred Laucht
    Klinik für Psychiatrie und Psychotherapie des Kindes und Jugendalters des Zentralinstituts für Seelische Gesundheit in Mannheim
    Z Kinder Jugendpsychiatr Psychother 32:177-85. 2004
    ..To examine the specifity of the association between maternal smoking during pregnancy and child behaviour problems...
  51. ncbi [Alcohol consumption in adolescence--social and individual influential factors]
    Anne Hinckers
    Klinik fur Psychiatrie und Psychotherapie des Kindes und Jugendalters, Zentralinstitut fur Seelische Gesundheit Mannheim
    Z Kinder Jugendpsychiatr Psychother 33:273-82; quiz 283-4. 2005
    ..To examine the influence of several social and individual factors on adolescent alcohol consumption...
  52. ncbi [Father negativity in the interaction with toddlers as predictor of internalizing problems in girls and boys at school age]
    Patricia Trautmann-Villalba
    Universitat Duisburg Essen, Standort Essen, Fachberich Bildungswissenschaften
    Prax Kinderpsychol Kinderpsychiatr 55:169-80. 2006
    ..In contrast, no predictive value of father negativity was observed in boys...
  53. ncbi [Factors influencing juvenile alcohol consumption: the role of gene-environment interactions]
    Anne S Hinckers
    Klinik für Psychosomatik und Psychotherapeutische Medizin, Zentralinstitut fur Seelische Gesundheit, Postfach 122 120, DE 68072 Mannheim
    Z Kinder Jugendpsychiatr Psychother 34:329-39; quiz 340-1. 2006
    ..This is in part due to the complex interactions between genotype and environment. In this article we review research on factors determining alcohol use by adolescents and on the development of an unifying model...
  54. doi Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior
    Gunter Schumann
    Interdisciplinary Research Group Addiction, MRC SGDP Center, Institute of Psychiatry at King s College, POB 080, London SE5 8AF, England
    Arch Gen Psychiatry 65:826-38. 2008
    ..Glutamatergic neurotransmission is implicated in alcohol-drinking behavior in animal models...
  55. pmc Nucleotide sequence variation within the PI3K p85 alpha gene associates with alcohol risk drinking behaviour in adolescents
    Sylvane Desrivieres
    Section of Addiction Biology, Interdisciplinary Research Group Addiction and NIHR Biomedical Research Centre, Institute of Psychiatry, King s College, London, United Kingdom
    PLoS ONE 3:e1769. 2008
    ....
  56. ncbi [Early onset of alcohol and tobacco use--indicator of enhanced risk of addiction?]
    Manfred Laucht
    Klinik fur Psychiatrie und Psychotherapie des Kindes und Jugendalters, Zentralinstitut fur Seelische Gesundheit Mannheim
    Z Kinder Jugendpsychiatr Psychother 35:137-43. 2007
    ....