C Laske

Summary

Country: Germany

Publications

  1. ncbi request reprint [Depression in Hashimoto's encephalopathy. Successful treatment of a severe depressive episode with a glucocorticoid as an add-on therapy]
    C Laske
    Universitätsklinik für Psychiatrie und Psychotherapie Tübingen
    Nervenarzt 76:617-22. 2005
  2. ncbi request reprint Stage-dependent BDNF serum concentrations in Alzheimer's disease
    C Laske
    Department of Psychiatry and Psychotherapy, University of Tübinger, Germany
    J Neural Transm 113:1217-24. 2006
  3. ncbi request reprint Macrophage colony-stimulating factor (M-CSF) in plasma and CSF of patients with mild cognitive impairment and Alzheimer's disease
    C Laske
    Department of Psychiatry and Psychotherapy, University of Tubingen, Osianderstr 24, D 72076 Tubingen, Germany
    Curr Alzheimer Res 7:409-14. 2010
  4. ncbi request reprint Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer's disease
    T Leyhe
    Department of Psychiatry and Psychotherapy, University of Tubingen, Osianderstrasse 24, Tubingen, Germany
    Eur Arch Psychiatry Clin Neurosci 258:124-8. 2008
  5. ncbi request reprint [Brain-derived neurotrophic factor: from nerve growth factor to modulator of brain plasticity in cognitive processes and psychiatric diseases]
    C Laske
    Universitätsklinik für Psychiatrie und Psychotherapie Tübingen
    Nervenarzt 77:523-37. 2006
  6. ncbi request reprint [Dementia as a primary symptom in late onset multiple sclerosis. Case series and review of the literature]
    T Leyhe
    Klinik für Psychiatrie und Psychotherapie der Universität Tübingen
    Nervenarzt 76:748-55. 2005
  7. ncbi request reprint [Alzheimer's disease with secondary Parkinson's syndrome. Case report of a patient with dementia and Parkinson's syndrome after long-term occupational exposure to insecticides, herbicides, and pesticides]
    C Laske
    Universitätsklinik für Psychiatrie und Psychotherapie Tübingen
    Nervenarzt 75:1107-11. 2004
  8. ncbi request reprint CD45RA+ ICAM-3+ lymphocytes in interferon-beta1b-treated and -untreated patients with relapsing-remitting multiple sclerosis
    N Chatzimanolis
    Research Group for Multiple Sclerosis and Neuroimmunology, Department of Neurology, Justus Liebig University of Giessen, Giessen, Germany
    Acta Neurol Scand 110:377-85. 2004
  9. ncbi request reprint Serum cytokine levels do not correlate with disease activity and severity assessed by brain MRI in multiple sclerosis
    J Kraus
    Department of Neurology, Research Group for Multiple Sclerosis and Neuroimmunology, Justus Liebig University Giessen, Giessen, Germany
    Acta Neurol Scand 105:300-8. 2002
  10. ncbi request reprint Cell surface bound and soluble adhesion molecules in CSF and blood in multiple sclerosis: correlation with MRI-measures of subclinical disease severity and activity
    J Kraus
    Department of Neurology, Justus Liebig University Giessen, Research Group for Multiple Sclerosis and Neuroimmunology, Am Steg 14, 35385, Giessen, Germany
    J Neuroimmunol 122:175-85. 2002

Collaborators

Detail Information

Publications12

  1. ncbi request reprint [Depression in Hashimoto's encephalopathy. Successful treatment of a severe depressive episode with a glucocorticoid as an add-on therapy]
    C Laske
    Universitätsklinik für Psychiatrie und Psychotherapie Tübingen
    Nervenarzt 76:617-22. 2005
    ..Diagnosis of HE should be included in diagnostic procedures in cases of therapy-refractory depression because of a good response of HE to steroids...
  2. ncbi request reprint Stage-dependent BDNF serum concentrations in Alzheimer's disease
    C Laske
    Department of Psychiatry and Psychotherapy, University of Tübinger, Germany
    J Neural Transm 113:1217-24. 2006
    ..BDNF should be further evaluated as a candidate marker for clinical diagnosis and therapeutic monitoring in Alzheimer's disease...
  3. ncbi request reprint Macrophage colony-stimulating factor (M-CSF) in plasma and CSF of patients with mild cognitive impairment and Alzheimer's disease
    C Laske
    Department of Psychiatry and Psychotherapy, University of Tubingen, Osianderstr 24, D 72076 Tubingen, Germany
    Curr Alzheimer Res 7:409-14. 2010
    ..8 pg/ml yielded 73.7% sensitivity and 75.0% specificity for diagnosing MCI patients in comparison with control subjects. In conclusion, our data indicate that M-CSF in CSF could be a putative biomarker for MCI...
  4. ncbi request reprint Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer's disease
    T Leyhe
    Department of Psychiatry and Psychotherapy, University of Tubingen, Osianderstrasse 24, Tubingen, Germany
    Eur Arch Psychiatry Clin Neurosci 258:124-8. 2008
    ..Thus, up-regulation of BDNF might be part of a neuroprotective effect of AChE-inhibitors. The molecular mechanism of this potentially disease-modifying mechanism of action of donepezil should be clarified...
  5. ncbi request reprint [Brain-derived neurotrophic factor: from nerve growth factor to modulator of brain plasticity in cognitive processes and psychiatric diseases]
    C Laske
    Universitätsklinik für Psychiatrie und Psychotherapie Tübingen
    Nervenarzt 77:523-37. 2006
    ..Measurement of BDNF serum concentrations may be of diagnostic value. Additionally, the influence of different strategies for BDNF allocation seems to be relevant for the treatment and prevention of the above psychiatric disorders...
  6. ncbi request reprint [Dementia as a primary symptom in late onset multiple sclerosis. Case series and review of the literature]
    T Leyhe
    Klinik für Psychiatrie und Psychotherapie der Universität Tübingen
    Nervenarzt 76:748-55. 2005
    ..Until now dementia as the primary symptomatology has not been described in patients older than 60 years. Possibly MS as a differential diagnosis in dementia as well as cognitive impairment as an initial symptom of MS is under-recognized...
  7. ncbi request reprint [Alzheimer's disease with secondary Parkinson's syndrome. Case report of a patient with dementia and Parkinson's syndrome after long-term occupational exposure to insecticides, herbicides, and pesticides]
    C Laske
    Universitätsklinik für Psychiatrie und Psychotherapie Tübingen
    Nervenarzt 75:1107-11. 2004
    ..In cerebral positron emission tomography, general hypometabolism was found with maxima biparietally and left frontally. The possible differential diagnosis of AD and Parkinson's syndrome is discussed...
  8. ncbi request reprint CD45RA+ ICAM-3+ lymphocytes in interferon-beta1b-treated and -untreated patients with relapsing-remitting multiple sclerosis
    N Chatzimanolis
    Research Group for Multiple Sclerosis and Neuroimmunology, Department of Neurology, Justus Liebig University of Giessen, Giessen, Germany
    Acta Neurol Scand 110:377-85. 2004
    ..Yet, the exact mechanisms by which these benefits are achieved remain unknown. CD45RA is a marker for naive T lymphocytes and intercellular adhesion molecule-3 (ICAM-3) is expressed on resting lymphocytes...
  9. ncbi request reprint Serum cytokine levels do not correlate with disease activity and severity assessed by brain MRI in multiple sclerosis
    J Kraus
    Department of Neurology, Research Group for Multiple Sclerosis and Neuroimmunology, Justus Liebig University Giessen, Giessen, Germany
    Acta Neurol Scand 105:300-8. 2002
    ..This study has been performed to investigate whether changes of cytokines correlate with morphological changes as determined by MRI...
  10. ncbi request reprint Cell surface bound and soluble adhesion molecules in CSF and blood in multiple sclerosis: correlation with MRI-measures of subclinical disease severity and activity
    J Kraus
    Department of Neurology, Justus Liebig University Giessen, Research Group for Multiple Sclerosis and Neuroimmunology, Am Steg 14, 35385, Giessen, Germany
    J Neuroimmunol 122:175-85. 2002
    ..In previous studies, we found that cell surface bound AM on mononuclear cells (MNC) in CSF and blood might be useful markers of clinical disease activity in MS patients...
  11. ncbi request reprint Prognostic value of soluble tumor necrosis factor receptors 1 and 2 in multiple sclerosis patients treated with interferon beta-1b
    C Laske
    Department of Neurology, Justus Liebig University, Giessen, Germany
    Eur Neurol 46:210-4. 2001
    ..This could help to establish a cost-effective prescription pattern for this expensive treatment, which is of importance for the future management of patients with MS...
  12. ncbi request reprint Induction of sTNF-R1 and sTNF-R2 by interferon beta-1b in correlation with clinical and MRI activity
    C Laske
    Department of Neurology, Justus-Liebig Univ, Giessen, Germany
    Acta Neurol Scand 103:105-13. 2001
    ..CONCLUSION: The present data suggest that IFN beta-1b induces the expression and shedding of TNF-R1 and TNF-R2. The magnitude of an increase of sTNF-Rs may be a marker for the effectiveness of treatment with IFN beta-1b...