C Langer

Summary

Country: Germany

Publications

  1. ncbi [Standardized sublay technique in polypropylene mesh repair of incisional hernia. A prospective clinical study]
    C Langer
    Klinik und Poliklinik für Allgemeinchirurgie, Georg August Universitat Gottingen
    Chirurg 72:953-7. 2001
  2. ncbi Surgical cure for early rectal carcinoma and large adenoma: transanal endoscopic microsurgery (using ultrasound or electrosurgery) compared to conventional local and radical resection
    C Langer
    Department of General Surgery, Georg August University Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Int J Colorectal Dis 18:222-9. 2003
  3. ncbi [Twenty-five years of experience in incisional hernia surgery. A comparative retrospective study of 432 incisional hernia repairs]
    C Langer
    Klinik und Poliklinik für Allgemeinchirurgie, Georg August Universitat, Gottingen
    Chirurg 74:638-45. 2003
  4. ncbi Prognostic factors influencing surgical management and outcome of gastrointestinal stromal tumours
    C Langer
    Department of General Surgery, Georg August University Gottingen, Germany
    Br J Surg 90:332-9. 2003
  5. ncbi Transanal endoscopic microsurgery (TEM) for minimally invasive resection of rectal adenomas and "Low-risk" carcinomas (uT1, G1 - 2)
    C Langer
    Department of General Surgery, Georg August University, Gottingen, Germany
    Z Gastroenterol 40:67-72. 2002
  6. ncbi Central mesh recurrence after incisional hernia repair with Marlex--are the meshes strong enough?
    C Langer
    Department of General Surgery, Georg August University Gottingen, Germany
    Hernia 5:164-7. 2001
  7. ncbi [Problem of recurrent incisional hernia after mesh repair of the abdominal wall]
    C Langer
    Klinik und Poliklinik für Allgemeinchirurgie, Georg August Universitat Gottingen
    Chirurg 72:927-33. 2001
  8. ncbi UltraCision or high-frequency knife in transanal endoscopic microsurgery (TEM)? Advantages of a new procedure
    C Langer
    Department of General Surgery, Georg August University Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Surg Endosc 15:513-7. 2001
  9. ncbi [Endosonography in epithelial rectal tumors. Value of a differentiated therapy concept]
    C Langer
    Klinik und Poliklinik für Allgemeinchirurgie, Klinikum der Georg August Universität Göttingen
    Chirurg 72:266-71. 2001
  10. doi Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletions
    F Haller
    Department of Pathology, Georg August University, Gottingen, Germany
    J Pathol 216:225-35. 2008

Collaborators

Detail Information

Publications41

  1. ncbi [Standardized sublay technique in polypropylene mesh repair of incisional hernia. A prospective clinical study]
    C Langer
    Klinik und Poliklinik für Allgemeinchirurgie, Georg August Universitat Gottingen
    Chirurg 72:953-7. 2001
    ..Special complications such as scar plates with restriction of the mobility of the abdominal wall, pain and fistula formation are described...
  2. ncbi Surgical cure for early rectal carcinoma and large adenoma: transanal endoscopic microsurgery (using ultrasound or electrosurgery) compared to conventional local and radical resection
    C Langer
    Department of General Surgery, Georg August University Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Int J Colorectal Dis 18:222-9. 2003
    ..The use of an ultrasonically activated scalpel rather than electrosurgery further improves the results of TEM...
  3. ncbi [Twenty-five years of experience in incisional hernia surgery. A comparative retrospective study of 432 incisional hernia repairs]
    C Langer
    Klinik und Poliklinik für Allgemeinchirurgie, Georg August Universitat, Gottingen
    Chirurg 74:638-45. 2003
    ..The relevance of different factors such as surgical technique, mesh material, and patient-related parameters concerning the outcome following mesh repair is still under debate...
  4. ncbi Prognostic factors influencing surgical management and outcome of gastrointestinal stromal tumours
    C Langer
    Department of General Surgery, Georg August University Gottingen, Germany
    Br J Surg 90:332-9. 2003
    ..The purpose of this study was to review surgical experience with gastrointestinal stromal tumours (GISTs) at a single tertiary university hospital, and to identify morphological and genetic prognostic markers of tumour progression...
  5. ncbi Transanal endoscopic microsurgery (TEM) for minimally invasive resection of rectal adenomas and "Low-risk" carcinomas (uT1, G1 - 2)
    C Langer
    Department of General Surgery, Georg August University, Gottingen, Germany
    Z Gastroenterol 40:67-72. 2002
    ..After palliative excision 2 recurrences occurred. These results of transanal endoscopic microsurgery (TEM) indicate that this technique has a useful place in curative, as well as in palliative management of rectal tumors...
  6. ncbi Central mesh recurrence after incisional hernia repair with Marlex--are the meshes strong enough?
    C Langer
    Department of General Surgery, Georg August University Gottingen, Germany
    Hernia 5:164-7. 2001
    ..To our knowledge, this is the first description of a central mesh recurrence, and we discuss a possible mechanism with particular emphasis on the required abdominal wall forces both physiologically and after incisional hernia repair...
  7. ncbi [Problem of recurrent incisional hernia after mesh repair of the abdominal wall]
    C Langer
    Klinik und Poliklinik für Allgemeinchirurgie, Georg August Universitat Gottingen
    Chirurg 72:927-33. 2001
    ..Depending on the surgical technique, mesh material and follow-up, the figures for recurrences of incisional hernia vary from 0 to 31%. What are the reasons for recurrences, and which options exist for more successful therapy?..
  8. ncbi UltraCision or high-frequency knife in transanal endoscopic microsurgery (TEM)? Advantages of a new procedure
    C Langer
    Department of General Surgery, Georg August University Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Surg Endosc 15:513-7. 2001
    ..In principle, all the known risks associated with the application of electric current can be avoided by using ultrasound technology...
  9. ncbi [Endosonography in epithelial rectal tumors. Value of a differentiated therapy concept]
    C Langer
    Klinik und Poliklinik für Allgemeinchirurgie, Klinikum der Georg August Universität Göttingen
    Chirurg 72:266-71. 2001
    ..Preoperative histology and endosonography determine the therapeutic strategy by using the criteria of depth of infiltration (uT) and lymph node status (uN)...
  10. doi Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletions
    F Haller
    Department of Pathology, Georg August University, Gottingen, Germany
    J Pathol 216:225-35. 2008
    ..Altogether, these observations suggest increased KIT signalling with up-regulation of cyclin D as the basis for the unfavourable clinical course in GISTs with KIT exon 11 deletions...
  11. ncbi Prognosis factors in incisional hernia surgery: 25 years of experience
    C Langer
    Department of General Surgery, Georg August University Gottingen, Robert Koch Str 40, 37075 Gottingen, Germany
    Hernia 9:16-21. 2005
    ..The relevance of different factors, like operative technique, mesh material, and patient-related parameters concerning the outcome following mesh repair, are still under debate...
  12. doi [Gastrointestinal stromal tumors from the surgical point of view. Laparoscopic therapy]
    C Langer
    Klinik für Allgemein und Visceralchirurgie, Georg August Universitat, Robert Koch Strasse 40, Gottingen, Germany
    Chirurg 79:644-9. 2008
    ..In principle laparoscopic GIST resections should be performed only by interdisciplinary teams of surgeons and gastroenterologists experienced in laparoscopy, endoscopy, and oncology...
  13. doi Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs)
    F Haller
    Department of Pathology, Georg August University, Gottingen, Germany
    J Pathol 215:253-62. 2008
    ..This study provides a possible basis for the accelerated proliferation and particularly malignant behaviour in GISTs with 9p loss...
  14. ncbi [Treatment of abdominal wall defects, including abdominal relaxation]
    C Langer
    Klinik und Poliklinik für Allgemeinchirurgie, Georg August Universitat Gottingen, Robert Koch Strasse 40, 37075 Gottingen
    Chirurg 77:414-23. 2006
    ..Treatment of abdominal wall defects must therefore be proposed on an individual basis utilizing one or a combination of the techniques described...
  15. ncbi An oncogenetic tree model in gastrointestinal stromal tumours (GISTs) identifies different pathways of cytogenetic evolution with prognostic implications
    B Gunawan
    Institute of Pathology, Department of General Surgery, University of Gottingen, Germany, and Department of Clinical Pathology and Cytology, Merkur University Hospital, Zagreb, Croatia
    J Pathol 211:463-70. 2007
    ..Thus, insights into the cytogenetic evolution obtained from oncogenetic tree models may eventually help to gain a better understanding of the heterogeneous site-dependent biological behaviour of GISTs...
  16. ncbi [In-vitro study of the cellular response of human fibroblasts cultured on alloplastic hernia meshes. Influence of mesh material and structure]
    C Langer
    Klinik und Poliklinik für Allgemeinchirurgie, Georg August Universitat Gottingen
    Chirurg 76:876-85. 2005
    ..Fibroblasts play a major key role during the process of mesh incorporation. This study was performed to investigate differences in cell morphology and proliferation of human fibroblasts cultured on different polypropylene meshes...
  17. pmc Two-stage hepatectomy (R0) with portal vein ligation--towards curing patients with extended bilobular colorectal liver metastases
    K Homayounfar
    Department of General and Visceral Surgery, University Medical Center Gottingen, Georg August University, Robert Koch Str 40, 37075 Gottingen, Germany
    Int J Colorectal Dis 24:409-18. 2009
    ....
  18. ncbi Gastrointestinal stromal tumor (GIST) -- single center experience of prolonged treatment with imatinib
    C G Schindler
    Department of Gastroenterology and Endocrinology, Georg August University, Gottingen, Germany
    Z Gastroenterol 43:267-73. 2005
    ..Here we report our results of prolonged treatment in comparison to a similar group of GIST patients who had died before imatinib became available...
  19. ncbi Paralysis of the femoral nerve following totally extraperitoneal laparascopic inguinal hernia repair
    B Lange
    Klinik und Poliklinik für Allgemeinchirurgie der Universitätsklinken Göttingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Surg Endosc 17:1157. 2003
    ..The prognosis is positive given the lack of macroscopic evidence of any direct damage to the nerve...
  20. ncbi [Cocaine-body-packing. Infrequent indication for laparotomy]
    A Schaper
    Giftinformationszentrum Nord der Länder Bremen, Hamburg, Niedersachsen und Schleswig Holstein, Bereich Humanmedizin, Georg August Universitat, Gottingen
    Chirurg 74:626-31. 2003
    ..quot;..
  21. ncbi [Ultrasound diagnosis of Meckel diverticulitis in adults]
    A Wilhelm
    Klinik und Poliklinik für Allgemeinchirurgie, Georg August Universitat Gottingen
    Z Gastroenterol 39:73-5. 2001
    ..A diameter of up to 40 mm and a well-defined wall of small bowel with 3 definite layers visible by ultrasound may help to distinguish between a Meckel's diverticulum and the appendix...
  22. ncbi [Simulation of surgical techniques in graduate education of the surgeon. An analysis of value and effect]
    P M Markus
    Abteilung für Allgemeinchirurgie, Georg August Universitat Gottingen, Robert Koch Strasse 40, 37075 Gottingen
    Chirurg 73:622-7. 2002
    ..Besides the teaching of new techniques, participants benefited above all from the repetitive training in surgical procedures...
  23. ncbi Randomized clinical trial comparing lightweight composite mesh with polyester or polypropylene mesh for incisional hernia repair
    J Conze
    Department of Surgery, University Clinic Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
    Br J Surg 92:1488-93. 2005
    ..A new generation of mesh has been developed with reduced polypropylene mass and increased pore size. The aim of this study was to compare standard mesh with new lightweight mesh in patients undergoing incisional hernia repair...
  24. ncbi Mesh penetration of the sigmoid colon following a transabdominal preperitoneal hernia repair
    B Lange
    Department of Surgery, University of Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Surg Endosc 17:157. 2003
    ..In this case report, we discuss this particular complication following the TAPP procedure. Subsequently, we describe the diagnostics as well as the surgical treatment necessary...
  25. ncbi [Present treatment strategies for rectal carcinoma]
    T Liersch
    Klinik für Allgemeinchirurgie, Universitätsklinikum Göttingen
    Chirurg 76:309-32; quiz 333-4. 2005
    ..This therapeutic approach led to a reduction in the 5-year local recurrence rate to 6% and disease-free survival of approximately 68% in advanced rectal cancer (overall survival: 76%)...
  26. ncbi [Preoperative diagnostic procedures in locally advanced rectal carcinoma (> or =T3 or N+). What does endoluminal ultrasound achieve at staging and restaging (after neoadjuvant radiochemotherapy) in contrast to computed tomography?]
    T Liersch
    Klinik und Poliklinik für Allgemeinchirurgie, Universitätsklinikum der Georg August Universität Göttingen
    Chirurg 74:224-34. 2003
    ..For staging and restaging, contrast-enhanced computed tomography (CT) is usually used. In specialised centers, the endorectal ultrasound (rES) may be preferred...
  27. ncbi Right atrial hemangioma in modern cardiac imaging
    C Langer
    Clin Res Cardiol 95:482-7. 2006
  28. pmc Multimodality in imaging calcific constrictive pericarditis
    C Langer
    Heart 92:1289. 2006
  29. ncbi Documentation of corneal donation and transplantation in Germany
    A Eichhorst
    DSO Gesellschaft für Gewebetransplantation mbH, Büro Halle, Halle, Germany
    Transplant Proc 34:2338. 2002
  30. ncbi Outcome of patients with a performance status of 2 in Eastern Cooperative Oncology Group Study E1594: a Phase II trial in patients with metastatic nonsmall cell lung carcinoma
    C J Sweeney
    Department of Medicine, Division of Hematology/Oncology, Indiana University Medical Center, Indianapolis, Indiana, USA
    Cancer 92:2639-47. 2001
    ..Alternative strategies need to be explored with therapy specifically tailored for this group of patients...
  31. ncbi Lack of efficacy of topotecan in the treatment of metastatic or recurrent squamous carcinoma of the head and neck: an Eastern Cooperative Oncology Group Trial (E3393)
    B A Murphy
    Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA
    Am J Clin Oncol 24:64-6. 2001
    ..Median survival for previously untreated patients was 4.6 months and 3.2 months for previously treated patients.Topotecan failed to demonstrate efficacy in patients with RMSCHN. Further evaluation of this agent is not planned...
  32. ncbi The importance of reporting corneal donors
    T Bredehorn
    DSO Gesellschaft für Gewebetransplantation mbH, Gemeinnützige Körperschaft, Büro Halle, Halle, Germany
    Transplant Proc 34:2339. 2002
  33. ncbi [The carcinogenic potential of biomaterials in hernia surgery]
    B M Ghadimi
    Klinik und Poliklinik für Allgemeinchirurgie, Universitätsklinikum Göttingen, Robert Koch Strasse 40, 37075 Gottingen
    Chirurg 73:833-7. 2002
    ..In conclusion, there are no data so far indicating a real risk for humans to develop malignant tumors due to implanted meshes. Therefore we further propagate the implantation of meshes in hernia repair in adult patients...
  34. ncbi Requirements for the acceptance of tissue donors for corneal donation
    T Bredehorn
    DSO Gesellschaft für Gewebetransplantation, Gemeinnützige Körperschaft, Büro Halle, Halle, Germany
    Transplant Proc 34:2340. 2002
  35. ncbi Assessment of brain death in cadaveric tissue donors
    T Bredehorn
    DSO Gesellschaft für Gewebetransplantation, Gemeinnützige Körperschaft, Büro Halle, Halle, Germany
    Transplant Proc 34:2344. 2002
  36. ncbi Indications for emergency keratoplasty at the University Eye Hospital of the Martin-Luther-University Halle-Wittenberg
    T Bredehorn
    DSO Gesellschaft für Gewebetransplantation, Gemeinnützige Körperschaft, Büro Halle, Halle, Germany
    Transplant Proc 34:2347. 2002
  37. ncbi Radiotherapy patterns of care study in lung carcinoma
    B Movsas
    Fox Chase Cancer Center, 7701 Burholme Ave, Philadelphia, PA 19111, USA
    J Clin Oncol 21:4553-9. 2003
    ..For the first time, a lung Patterns of Care Study was conducted to determine the national patterns of radiation (RT) practice in patients treated for nonmetastatic lung cancer in 1998 to 1999...
  38. ncbi Follow-up and results of penetrating keratoplasty
    T Bredehorn
    DSO Gesellschaft für Gewebetransplantation, Gemeinnützige Körperschaft, Büro Halle, Halle, Germany
    Transplant Proc 34:2348. 2002
  39. ncbi Constant availability of emergency cornea transplants in central German Corneabank Halle
    T Bredehorn
    DSO Gesellschaft für Gewebetransplantation, Gemeinnützige Körperschaft, Büro Halle, Halle, Germany
    Transplant Proc 34:2351-2. 2002
  40. ncbi [A bipolar radial head prosthesis after comminuted radial head fractures: indications, treatment and outcome after 5 years]
    K H Frosch
    Klinik für Unfallchirurgie, Plastische und Wiederherstellungschirurgie, Georg August Universitat Gottingen
    Unfallchirurg 106:367-73. 2003
    ....
  41. ncbi Atrial fibrillation in carcinoid heart disease: The role of serotonin. A review of the literature
    C Langer
    Clin Res Cardiol 96:114-8. 2007