Karl H Ladwig

Summary

Country: Germany

Publications

  1. pmc Posttraumatic stress disorder and not depression is associated with shorter leukocyte telomere length: findings from 3,000 participants in the population-based KORA F4 study
    Karl Heinz Ladwig
    Institute of Epidemiology II, Helmholtz Zentrum Munchen German Research Center for Environmental Health, Neuherberg, Germany
    PLoS ONE 8:e64762. 2013
  2. doi request reprint Are psychosocial stressors associated with the relationship of alcohol consumption and all-cause mortality?
    Esther Ruf
    Institute of Epidemiology II, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Ingolstädter Landstr, 1, 85764 Neuherberg, Germany
    BMC Public Health 14:312. 2014
  3. ncbi request reprint Stable time patterns of railway suicides in Germany: comparative analysis of 7,187 cases across two observation periods (1995-1998; 2005-2008)
    Karoline Lukaschek
    Institute of Epidemiology II, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Ingolstadter Landstr 1, Neuherberg 85764, Germany
    BMC Public Health 14:124. 2014
  4. pmc Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study
    Tao Xu
    Research Unit of Molecular Epidemiology, Helmholtz Zentrum Munchen, Ingolstädter Landstraße 1, Neuherberg 85764, Germany
    BMC Med 11:60. 2013
  5. pmc The association of smoking status with healthcare utilisation, productivity loss and resulting costs: results from the population-based KORA F4 study
    Margarethe Wacker
    Helmholtz Zentrum Munchen German Research Center for Environmental Health GmbH, Institute of Health Economics and Health Care Management, Member of the German Center for Lung Research, Comprehensive Pneumology Center Munich CPC M, Ingolstaedter Landstr, 1, Neuherberg 85764, Germany
    BMC Health Serv Res 13:278. 2013
  6. doi request reprint Job strain-associated inflammatory burden and long-term risk of coronary events: findings from the MONICA/KORA Augsburg case-cohort study
    Rebecca T Emeny
    Institute of Epidemiology II, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany
    Psychosom Med 75:317-25. 2013
  7. doi request reprint Determinants and trajectory of phobic anxiety in patients living with an implantable cardioverter defibrillator
    En Young Nicole Cho
    Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Ingolstaedter Landstrasse 1, Neuherberg, Germany
    Heart 98:806-12. 2012
  8. pmc Do diabetes and depressed mood affect associations between obesity and quality of life in postmenopause? Results of the KORA-F3 Augsburg population study
    Daniela A Heidelberg
    Hannover Medical School, Hannover, Germany
    Health Qual Life Outcomes 9:97. 2011
  9. pmc Behaviour patterns preceding a railway suicide: explorative study of German Federal Police officers' experiences
    Karoline Lukaschek
    Institute of Epidemiology II, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Ingolstadter Landstr 1, 85764 Neuherberg, Germany
    BMC Public Health 11:620. 2011
  10. pmc Association of daily tar and nicotine intake with incident myocardial infarction: results from the population-based MONICA/KORA Augsburg Cohort Study 1984-2002
    Qiu Li Zhang
    Institute of Epidemiology II, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Ingolstadter Landstrasse 1, 85764 Neuherberg, Germany
    BMC Public Health 11:273. 2011

Collaborators

Detail Information

Publications37

  1. pmc Posttraumatic stress disorder and not depression is associated with shorter leukocyte telomere length: findings from 3,000 participants in the population-based KORA F4 study
    Karl Heinz Ladwig
    Institute of Epidemiology II, Helmholtz Zentrum Munchen German Research Center for Environmental Health, Neuherberg, Germany
    PLoS ONE 8:e64762. 2013
    ..We analysed the impact of Posttraumatic Stress Disorder (PTSD) on TL in the general population and postulated a dose-dependent TL association in subjects suffering from partial PTSD compared to full PTSD...
  2. doi request reprint Are psychosocial stressors associated with the relationship of alcohol consumption and all-cause mortality?
    Esther Ruf
    Institute of Epidemiology II, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Ingolstädter Landstr, 1, 85764 Neuherberg, Germany
    BMC Public Health 14:312. 2014
    ..As psychosocial stressors are among those factors that have not been sufficiently controlled for, we assessed whether they may confound the relationship between alcohol consumption and all-cause mortality...
  3. ncbi request reprint Stable time patterns of railway suicides in Germany: comparative analysis of 7,187 cases across two observation periods (1995-1998; 2005-2008)
    Karoline Lukaschek
    Institute of Epidemiology II, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Ingolstadter Landstr 1, Neuherberg 85764, Germany
    BMC Public Health 14:124. 2014
    ....
  4. pmc Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study
    Tao Xu
    Research Unit of Molecular Epidemiology, Helmholtz Zentrum Munchen, Ingolstädter Landstraße 1, Neuherberg 85764, Germany
    BMC Med 11:60. 2013
    ..Here, we extend our metabolomics study with a large prospective study including female smokers and quitters...
  5. pmc The association of smoking status with healthcare utilisation, productivity loss and resulting costs: results from the population-based KORA F4 study
    Margarethe Wacker
    Helmholtz Zentrum Munchen German Research Center for Environmental Health GmbH, Institute of Health Economics and Health Care Management, Member of the German Center for Lung Research, Comprehensive Pneumology Center Munich CPC M, Ingolstaedter Landstr, 1, Neuherberg 85764, Germany
    BMC Health Serv Res 13:278. 2013
    ..This population-based cross-sectional study compares healthcare utilisation, direct medical costs, and costs of productivity losses for different smoking groups: current smokers, former smokers, and never smokers...
  6. doi request reprint Job strain-associated inflammatory burden and long-term risk of coronary events: findings from the MONICA/KORA Augsburg case-cohort study
    Rebecca T Emeny
    Institute of Epidemiology II, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany
    Psychosom Med 75:317-25. 2013
    ..We examined the association between job strain and coronary heart disease (CHD) and investigated the role of markers of inflammation and endothelial dysfunction as possible mediators of job strain-associated CHD risk...
  7. doi request reprint Determinants and trajectory of phobic anxiety in patients living with an implantable cardioverter defibrillator
    En Young Nicole Cho
    Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Ingolstaedter Landstrasse 1, Neuherberg, Germany
    Heart 98:806-12. 2012
    ..Phobic anxiety predicts ventricular arrhythmia in coronary heart disease patients, but little is known about phobic anxiety in ICD patients. This study aimed to identify determinants and the course of phobic anxiety in ICD patients...
  8. pmc Do diabetes and depressed mood affect associations between obesity and quality of life in postmenopause? Results of the KORA-F3 Augsburg population study
    Daniela A Heidelberg
    Hannover Medical School, Hannover, Germany
    Health Qual Life Outcomes 9:97. 2011
    ..To assess associations of obesity with health-related quality of life (HRQL) in postmenopausal women, and whether depressed mood and diabetes moderate these associations...
  9. pmc Behaviour patterns preceding a railway suicide: explorative study of German Federal Police officers' experiences
    Karoline Lukaschek
    Institute of Epidemiology II, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Ingolstadter Landstr 1, 85764 Neuherberg, Germany
    BMC Public Health 11:620. 2011
    ..The main question of the present study was whether pre-crash railway suicide behaviour can be identified, using German Federal Police officers experience with suicidal events in railway related environments...
  10. pmc Association of daily tar and nicotine intake with incident myocardial infarction: results from the population-based MONICA/KORA Augsburg Cohort Study 1984-2002
    Qiu Li Zhang
    Institute of Epidemiology II, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Ingolstadter Landstrasse 1, 85764 Neuherberg, Germany
    BMC Public Health 11:273. 2011
    ..To bridge this gap, we conducted an analysis in a large prospective study from Southern Germany investigating associations of daily tar and nicotine intake with an incident MI event...
  11. pmc Socio-economic differences in life expectancy among persons with diabetes mellitus or myocardial infarction: results from the German MONICA/KORA study
    Laura Perna
    Institute of Health Economics and Health Care Management, Helmholtz Zentrum Munchen, German Research Centre for Environmental Health, Neuherberg, Germany
    BMC Public Health 10:135. 2010
    ....
  12. pmc Mental health in the aged: prevalence, covariates and related neuroendocrine, cardiovascular and inflammatory factors of successful aging
    Maria E Lacruz
    Institut für Epidemiologie Helmholtz Zentrum München, Munchen, Germany
    BMC Med Res Methodol 10:36. 2010
    ..Specifically, we aim to identify predictors of successful aging and to elucidate bio-psychosocial mechanisms that maintain mental health and successful adaptation despite adverse experiences of life and aging...
  13. doi request reprint [Treating ICD patients at the end of their lives: attitudes, knowledge, and behavior of doctors and patients. A critical literature analysis]
    K H Ladwig
    Institut für Epidemiologie EPI II, Helmholtz Zentrum Munchen, Deutsches Forschungszentrum für Gesundheit und Umwelt, Ingolstadter Landstr 1, 85764, Neuherberg, Deutschland
    Herzschrittmacherther Elektrophysiol 22:151-6. 2011
    ..However, the ethical dilemma of harming a dying patient has received little attention. We studied the current state of knowledge and behavior of physicians and the subjective needs of ICD patients with respect to end-of-life issues...
  14. doi request reprint [Depression. An underestimated risk for the development and progression of coronary heart disease]
    K H Ladwig
    Institut fur Epidemiologie, Helmholtz Zentrum Munchen, Deutsches Forschungszentrum für Gesundheit und Umwelt, Neuherberg, Ingolstadter Landstr 1, 85764, Neuherberg
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 54:59-65. 2011
    ..Nonadherence and adverse side effects of medications also contribute to the lethal properties of depression in CVD...
  15. doi request reprint Sex and age specific time patterns and long term time trends of pre-hospital delay of patients presenting with acute ST-segment elevation myocardial infarction
    Karl Heinz Ladwig
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Int J Cardiol 152:350-5. 2011
    ..We examined time patterns and long term time trends of pre-hospital delay time (PHDT) of STEMI patients...
  16. doi request reprint Screening for multiple somatic complaints in a population-based survey: does excessive symptom reporting capture the concept of somatic symptom disorders? Findings from the MONICA-KORA Cohort Study
    Karl Heinz Ladwig
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, 85764 Neuherberg, Germany
    J Psychosom Res 68:427-37. 2010
    ..We aimed to explore whether ESR captures the concept of somatic symptom disorders regardless of the patient's disease status or the degree of symptom burden...
  17. doi request reprint [The inner barrier: how health psychology concepts contribute to the explanation of prehospital delays in acute myocardial infarction: a systematic analysis of the current state of knowledge]
    Karl Heinz Ladwig
    Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie des Klinikums rechts der Isar, Technische Universitat Munchen
    Psychother Psychosom Med Psychol 59:440-5. 2009
    ..Negative outcome expectancies and an impaired perceived self-efficacy, predominately in subjects with co-morbid negative affectivity are likely to contribute to delay...
  18. doi request reprint Posttraumatic stress symptoms and predicted mortality in patients with implantable cardioverter-defibrillators: results from the prospective living with an implanted cardioverter-defibrillator study
    Karl Heinz Ladwig
    Institute of Epidemiology, Helmholtz Zentrum National Research Center for Environmental Health, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany
    Arch Gen Psychiatry 65:1324-30. 2008
    ..Posttraumatic stress disorder (PTSD) is generally overlooked in cardiac patients, and no study to date (to our knowledge) has evaluated the effect of PTSD symptoms on the prognosis in patients with ICDs...
  19. doi request reprint Sex- and age-related increase in prevalence rates of death wishes and suicidal ideation in the community: results from the KORA-F3 Augsburg Study with 3,154 men and women, 35 to 84 years of age
    Karl Heinz Ladwig
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    Psychiatry Res 161:248-52. 2008
    ..The population-based approach demonstrates a substantial proportion of subjects suffering from SID, particularly in older age groups...
  20. doi request reprint The railway suicide death of a famous German football player: impact on the subsequent frequency of railway suicide acts in Germany
    Karl Heinz Ladwig
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology II, Neuherberg, Germany
    J Affect Disord 136:194-8. 2012
    ..The railway suicide of Robert Enke, an internationally respected German football goal keeper, sent shockwaves throughout the world of football. We analyzed its impact on the frequency of subsequent railway suicide acts (RS)...
  21. pmc Metabolic profiling reveals distinct variations linked to nicotine consumption in humans--first results from the KORA study
    Rui Wang-Sattler
    Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany
    PLoS ONE 3:e3863. 2008
    ..Our findings provide new insight into the pathophysiology of smoking addiction. Activation of the enzyme alkyl-DHAP by small molecules may provide novel routes for therapy...
  22. pmc Prospective association between self-reported life satisfaction and mortality: results from the MONICA/KORA Augsburg S3 survey cohort study
    Maria E Lacruz
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology II, Neuherberg, Germany
    BMC Public Health 11:579. 2011
    ..To identify factors which determine high life satisfaction (LS) and to analyse the prognostic influence of LS on mortality...
  23. doi request reprint Socioeconomic position, resilience, and health behaviour among elderly people
    Laura Perna
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Health Economics and Health Care Management, P O Box 1129, 85758, Neuherberg, Germany
    Int J Public Health 57:341-9. 2012
    ....
  24. ncbi request reprint Contemplating to quit current smoking status: differences in behavioural and psychosocial patterns in a population-based cohort of current smokers
    Karl Heinz Ladwig
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstr 1, Neuherberg 85764, Germany
    Prev Med 41:134-40. 2005
    ..Smokers actively considering to quit smoking were compared with hard-core smokers completely unwilling to change smoking habits with respect to psychosocial variables...
  25. ncbi request reprint C-reactive protein, depressed mood, and the prediction of coronary heart disease in initially healthy men: results from the MONICA-KORA Augsburg Cohort Study 1984-1998
    Karl Heinz Ladwig
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstr 1, 85764 Neuherberg, Germany
    Eur Heart J 26:2537-42. 2005
    ..The goal of the present study was to assess possible combined effects of these factors on the prediction of a future fatal and non-fatal coronary event...
  26. doi request reprint Increasing railway suicide acts after media coverage of a fatal railway accident? An ecological study of 747 suicidal acts
    Sabine Kunrath
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
    J Epidemiol Community Health 65:825-8. 2011
    ..We examined whether widespread media coverage of a railway accident, in which several people were killed while investigating a presumed railway suicide, subsequently increased the number of railway suicides...
  27. pmc Sex- and age-specific trends in mortality from suicide and undetermined death in Germany 1991-2002
    Jens J Baumert
    Institute of Epidemiology, GSF National Research Center for Environment and Health, Ingolstaedter Landstr, 1, 85764 Neuherberg, Germany
    BMC Public Health 5:61. 2005
    ..To date, it is not established whether those favourable time trends developed homogeneously for sex and age groups and how they were affected by the number of undetermined deaths...
  28. ncbi request reprint Influence of depressive mood on the association of CRP and obesity in 3205 middle aged healthy men
    Karl Heinz Ladwig
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstr 1, Neuherberg 85764, Germany
    Brain Behav Immun 17:268-75. 2003
    ..These findings suggest a possible synergistic effect of obesity and depressive mood on chronic low level inflammation which may play a crucial role in the pathogenesis of atherosclerosis...
  29. ncbi request reprint Case-finding for depressive and exhausted mood in the general population: reliability and validity of a symptom-driven diagnostic scale. Results from the prospective MONICA/KORA Augsburg Study
    Karl Heinz Ladwig
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Ann Epidemiol 14:332-8. 2004
    ..Depressed and exhausted mood warrants epidemiological scrutiny as a cardiovascular risk factor. We evaluated the reliability and validity of a symptom-driven diagnostic scale...
  30. ncbi request reprint Psychophysiological correlates of peritraumatic dissociative responses in survivors of life-threatening cardiac events
    Karl Heinz Ladwig
    Institut und Poliklinik für Psychosomatische Medizin, Medizinische Psychologie und Psychotherapie, Klinikum rechts der Isar, Technische Universitat Munchen, Germany
    Psychopathology 35:241-8. 2002
    ..DISS patients without PTSD exhibited balanced autonomic responses to the startle trials. DISS may, therefore, unfold malignant properties only in combination with persistent physiological hyperarousability...
  31. ncbi request reprint The Impact of Event Scale--Revised: evaluation of the subscales and correlations to psychophysiological startle response patterns in survivors of a life-threatening cardiac event: an analysis of 129 patients with an implanted cardioverter defibrillator
    Jens Baumert
    Institut und Poliklinik für Psychosomatische Medizin, Psychotherapie und Med Psychologie Universitätsklinikum rechts der Isar der Technischen Universität München, Munich, Germany
    J Affect Disord 82:29-41. 2004
    ....
  32. ncbi request reprint [Anxiety, depression, performance pressure: How much does psychological stress affect the heart? (interview by Waldtraud Paukstadt)]
    Karl Heinz Ladwig
    MMW Fortschr Med 146:17. 2004
  33. ncbi request reprint Psychophysiologic and affective parameters associated with pain intensity of cardiac cardioverter defibrillator shock discharges
    Jens Baumert
    Klinik und Poliklinik für Psychosomatische Medizin, Psychotherapie und Medizinische Psychologie, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Germany
    Psychosom Med 68:591-7. 2006
    ..The present study aimed to examine whether the strength of perceived shock pain is influenced by affective and psychophysiologic parameters...
  34. ncbi request reprint High psychiatric comorbidity in spasmodic torticollis: a controlled study
    Harald Gündel
    Institut und Poliklinik für Psychosomatische Medizin, Psychotherapie und Medizinische Psychologie, TU Munchen, Klinikum rechts der Isar, Langerstr 3, D 81675 Munchen, Germany
    J Nerv Ment Dis 191:465-73. 2003
    ..We conclude that high psychiatric comorbidity in ST is unlikely to be a mere consequence of chronic disease and disfigurement...
  35. ncbi request reprint Characteristics associated with low treatment satisfaction in patients with implanted cardioverter defibrillators: results from the LICAD study
    Karl Heinz Ladwig
    Institut und Poliklinik für Psychosomatische Medizin, Psychotherapie und Med Psychologie des Klinikums rechts der Isar der Technischen Universität München, Langerstrasse 3, 81675 Munich, Germany
    Pacing Clin Electrophysiol 28:506-13. 2005
    ..001). Thus, LTS serves as surrogate measure for deteriorated psychic health. Clinicians should be advised to identify LTS patients and to consider psychotherapeutic counseling for them...
  36. ncbi request reprint Exaggerated electrodermal startle responses after intracardiac shock discharges in patients with implanted cardioverter defibrillators
    Karl Heinz Ladwig
    Institut und Poliklinik für Psychosomatische Medizin, Med Psychologie und Psychotherapie des Klinikums Rechts der Isar der Technischen Universität München, Munchen, Germany
    Psychosom Med 65:222-8. 2003
    ..We studied whether repetitive intracardiac shock discharges of implantable cardioverter defibrillators (ICDs) provoke an enduring enhancement of startle responses...
  37. ncbi request reprint Patterns of suicidal behaviour in a metro subway system: a study of 306 cases injured by the Munich subway, 1980-1999
    Karl Heinz Ladwig
    Institut und Poliklinik für Psychosomatische Medizin, Psychotherapie und Med Psychologie des Klinikums rechts der Isar der Technischen Universität München, Germany
    Eur J Public Health 14:291-5. 2004
    ..As a basis for preventive strategies to reduce subway suicides, an investigation was undertaken to determine if there was a distinct pattern of subway suicidal behaviour...