Lutz Kretschmer

Summary

Country: Germany

Publications

  1. ncbi request reprint Standardized axillary lymphadenectomy improves local control but not survival in patients with palpable lymph node metastases of cutaneous malignant melanoma
    L Kretschmer
    Abteilung Dermatologie und Venerologie, , v.-Siebold-Str. 3, , Germany
    Langenbecks Arch Surg 386:418-25. 2001
  2. ncbi request reprint [Sentinel lymph node biopsy in malignant melanoma--an update]
    Lutz Kretschmer
    Abteilung Dermatologie und Venerologie, Georg August Universitat Gottingen, Germany
    J Dtsch Dermatol Ges 1:777-84. 2003
  3. pmc Individualized surgery: gamma-probe-guided lymphadenectomy in patients with clinically enlarged lymph node metastases from melanomas
    Lutz Kretschmer
    Department of Dermatology, Venereology and Allergology, Georg August University, Gottingen, Germany
    Ann Surg Oncol 20:1714-21. 2013
  4. doi request reprint Leg swelling after inguinal sentinel lymph node biopsy and primary melanoma excision with a safety margin
    Lutz Kretschmer
    Department of Dermatology, Venereology and Allergology, University of Gottingen, Robert Koch Straße 3, Gottingen, Germany
    J Dtsch Dermatol Ges 10:733-9. 2012
  5. ncbi request reprint [Intraoperative detection of sentinel lymph nodes in cutaneous malignant melanoma -- blue dye alone versus blue dye plus gamma detection]
    Lutz Kretschmer
    Abteilung Dermatologie und Venerologie, Georg August Universitat Gottingen, Germany
    J Dtsch Dermatol Ges 3:615-22. 2005
  6. ncbi request reprint Factors predicting the risk of in-transit recurrence after sentinel lymphonodectomy in patients with cutaneous malignant melanoma
    Lutz Kretschmer
    Department of Dermatology, Georg August University Gottingen, v Siebold Str 3, D 37075 Gottingen, Germany
    Ann Surg Oncol 13:1105-12. 2006
  7. doi request reprint Postoperative morbidity of lymph node excision for cutaneous melanoma-sentinel lymphonodectomy versus complete regional lymph node dissection
    Lutz Kretschmer
    Department of Dermatology, Georg August University of Gottingen, Gottingen, Germany
    Melanoma Res 18:16-21. 2008
  8. ncbi request reprint Patients with lymphatic metastasis of cutaneous malignant melanoma benefit from sentinel lymphonodectomy and early excision of their nodal disease
    L Kretschmer
    Department of Dermatology, Georg August University of Gottingen, v Siebold Str 3, D 37075 Gottingen, Germany
    Eur J Cancer 40:212-8. 2004
  9. doi request reprint The popliteal fossa - a problem zone for sentinel lymphonodectomy
    Lutz Kretschmer
    Department of Dermatology, Verereology and Allergology, University of Gottingen, Germany
    J Dtsch Dermatol Ges 9:123-7. 2011
  10. doi request reprint Age as a key factor influencing metastasizing patterns and disease-specific survival after sentinel lymph node biopsy for cutaneous melanoma
    Lutz Kretschmer
    Department of Dermatology, Venereology and Allergology, Georg August University of Goettingen, Gottingen, Germany
    Int J Cancer 129:1435-42. 2011

Detail Information

Publications31

  1. ncbi request reprint Standardized axillary lymphadenectomy improves local control but not survival in patients with palpable lymph node metastases of cutaneous malignant melanoma
    L Kretschmer
    Abteilung Dermatologie und Venerologie, , v.-Siebold-Str. 3, , Germany
    Langenbecks Arch Surg 386:418-25. 2001
    ....
  2. ncbi request reprint [Sentinel lymph node biopsy in malignant melanoma--an update]
    Lutz Kretschmer
    Abteilung Dermatologie und Venerologie, Georg August Universitat Gottingen, Germany
    J Dtsch Dermatol Ges 1:777-84. 2003
    ..Unfortunately, an unequivocally acknowledged adjuvant therapy is lacking. Moreover, the impact of complete lymph node dissection after positive sentinel biopsy on survival or local disease control has not yet been clarified...
  3. pmc Individualized surgery: gamma-probe-guided lymphadenectomy in patients with clinically enlarged lymph node metastases from melanomas
    Lutz Kretschmer
    Department of Dermatology, Venereology and Allergology, Georg August University, Gottingen, Germany
    Ann Surg Oncol 20:1714-21. 2013
    ..Therapeutic lymph node dissection (TLND) is regarded as the clinical standard, but the appropriate extent of TLND is controversial in all lymphatic basins...
  4. doi request reprint Leg swelling after inguinal sentinel lymph node biopsy and primary melanoma excision with a safety margin
    Lutz Kretschmer
    Department of Dermatology, Venereology and Allergology, University of Gottingen, Robert Koch Straße 3, Gottingen, Germany
    J Dtsch Dermatol Ges 10:733-9. 2012
    ..Risk-factors for leg swelling following primary melanoma excision and inguinal sentinel lymphadenectomy (SLNE) have not been sufficiently investigated...
  5. ncbi request reprint [Intraoperative detection of sentinel lymph nodes in cutaneous malignant melanoma -- blue dye alone versus blue dye plus gamma detection]
    Lutz Kretschmer
    Abteilung Dermatologie und Venerologie, Georg August Universitat Gottingen, Germany
    J Dtsch Dermatol Ges 3:615-22. 2005
    ..In this retrospective study, further aspects related to the introduction of gamma-guided preparation are analysed in detail...
  6. ncbi request reprint Factors predicting the risk of in-transit recurrence after sentinel lymphonodectomy in patients with cutaneous malignant melanoma
    Lutz Kretschmer
    Department of Dermatology, Georg August University Gottingen, v Siebold Str 3, D 37075 Gottingen, Germany
    Ann Surg Oncol 13:1105-12. 2006
    ..In-transit metastasis is an important morbidity factor after sentinel lymphonodectomy (SLNE). So far, factors posing an increased risk after SLNE have not been adequately analyzed...
  7. doi request reprint Postoperative morbidity of lymph node excision for cutaneous melanoma-sentinel lymphonodectomy versus complete regional lymph node dissection
    Lutz Kretschmer
    Department of Dermatology, Georg August University of Gottingen, Gottingen, Germany
    Melanoma Res 18:16-21. 2008
    ..In contrast, CLND has been demonstrated to be a major and potentially morbid surgical procedure. This highlights the importance of testing the therapeutic value that CLND adds to the sentinel lymph node procedure...
  8. ncbi request reprint Patients with lymphatic metastasis of cutaneous malignant melanoma benefit from sentinel lymphonodectomy and early excision of their nodal disease
    L Kretschmer
    Department of Dermatology, Georg August University of Gottingen, v Siebold Str 3, D 37075 Gottingen, Germany
    Eur J Cancer 40:212-8. 2004
    ..In cutaneous malignant melanoma, early excision of lymphatic metastases, directed by the sentinel node procedure, provides a highly significant overall survival benefit...
  9. doi request reprint The popliteal fossa - a problem zone for sentinel lymphonodectomy
    Lutz Kretschmer
    Department of Dermatology, Verereology and Allergology, University of Gottingen, Germany
    J Dtsch Dermatol Ges 9:123-7. 2011
    ..The impact of lymphatic drainage to popliteal sentinel lymph nodes (SLNs) has yet to be explored in detail...
  10. doi request reprint Age as a key factor influencing metastasizing patterns and disease-specific survival after sentinel lymph node biopsy for cutaneous melanoma
    Lutz Kretschmer
    Department of Dermatology, Venereology and Allergology, Georg August University of Goettingen, Gottingen, Germany
    Int J Cancer 129:1435-42. 2011
    ..Younger patients have a better prognosis despite their higher probability of SLN metastasis. Older patients are less frequently SLN-positive but have a higher risk of loco-regional recurrence...
  11. ncbi request reprint Dynamic lymphoscintigraphy and image fusion of SPECT and pelvic CT-scans allow mapping of aberrant pelvic sentinel lymph nodes in malignant melanoma
    L Kretschmer
    Department of Dermatology, Georg August Universitat Gottingen, v Siebold Str 3, D 37075 Gottingen, Germany
    Eur J Cancer 39:175-83. 2003
    ..The significance of radioactively labelled pelvic lymph nodes for the probability of pelvic metastases should be analysed further...
  12. ncbi request reprint Cutting a sentinel lymph node into slices is the optimal first step for examination of sentinel lymph nodes in melanoma patients
    Christina Mitteldorf
    Department of Dermatology, Venerology and Allergology, Georg August University of Goettingen, Goettingen, Germany
    Mod Pathol 22:1622-7. 2009
    ..Compared with the bivalving protocol, the multiple slices protocol was less labor intensive for the technical staff...
  13. doi request reprint Lymph node ultrasound during melanoma follow-up significantly improves metastasis detection compared with clinical examination alone: a study on 433 patients
    Ullrich Kruger
    Department of Dermatology, Venereology and Allergology, University of Gottingen, Germany
    Melanoma Res 21:457-63. 2011
    ..73% of clinically metastasis-free investigations (n=22). Our data suggest that high-frequency sonography should be part of all melanoma follow-up investigations, independent of melanoma type, melanoma stage, or lymph node biopsy status...
  14. doi request reprint Lower prevalence of lymphatic metastasis and poorer survival of the sentinel node-negative patients limit the prognostic value of sentinel node biopsy for head or neck melanomas
    Philipp Al Ghazal
    aDepartment of Dermatology and Allergy, Hannover Medical School, Skin Cancer Center Hannover, Hannove bDepartment of Dermatology and Allergology, Klinikum Augsburg, Augsburg cDepartment of Dermatology, Venereology and Allergology, Georg August University, Göttingen dDepartment of Dermatology, Venereology and Allergology, Klinikum Hildesheim GmbH, Hildesheim, Germany
    Melanoma Res 24:158-64. 2014
    ..As a result, the prognostic information provided by the SLN for HNM seems less important. Decision making for SLNE in HNM should be carefully balanced considering the potential morbidity of the procedure. ..
  15. ncbi request reprint A new family with the rare genodermatosis keratosis punctata palmoplantaris Buschke-Fischer-Brauer
    Steffen Emmert
    Department of Dermatology, University of Gottingen, von Siebold Strasse 3, 37075 Gottingen, Germany
    J Am Acad Dermatol 49:1166-9. 2003
    ..Punctate keratoses coalesced into hyperkeratotic plaques on pressure points. Identification of additional families is necessary to permit definitive genetic classification of this genodermatosis...
  16. ncbi request reprint Sentinel node biopsy improves prognostic stratification in patients with thin (pT1) melanomas and an additional risk factor
    Christina Mitteldorf
    Department of Dermatology, Venereology and Allergology, Klinikum Hildesheim GmbH, Hildesheim, Germany
    Ann Surg Oncol 21:2252-8. 2014
    ..Sentinel lymph node (SLN) biopsy (SLNB) for pT1 melanomas is not generally recognized as a clinical standard. We studied the value of SLNB for pT1 melanoma patients having at least one additional risk factor...
  17. ncbi request reprint Multicentric malignant melanoma in a giant melanocytic congenital nevus 20 years after dermabrasion in adulthood
    Markus Zutt
    Department of Dermatology, University of Goettingen, Goettingen, Germany
    Dermatol Surg 29:99-101; discussion 101. 2003
    ..Treatment is recommended to reduce the risk of spontaneous malignant transformation of giant nevi into malignant melanomas that usually occur in childhood...
  18. doi request reprint Increased Lipoprotein (a) concentrations in patients with chronic venous leg ulcers: a study on patients with or without postthrombotic syndrome
    Markus Zutt
    Department of Dermatology, Venereology and Allergology, University of Gottingen, Gottingen, Germany
    Wound Repair Regen 19:168-72. 2011
    ..Elevated concentrations may contribute to the pathogenesis through induction of thrombogenic microcirculatory dysregulations, impaired extravascular fibrinolysis, or other mechanisms like proinflammatory effects...
  19. ncbi request reprint 47 patients in 14 families with the rare genodermatosis keratosis punctata palmoplantaris Buschke-Fischer-Brauer
    Steffen Emmert
    Department of Dermatology, University of Goettingen, von Siebold Strasse 3, Germany
    Eur J Dermatol 13:16-20. 2003
    ..Continuous systemic retinoid treatment can clear symptoms. Future genetic classification on a molecular basis may reveal the existence of more than one entity of this clinically heterogeneous genodermatosis...
  20. ncbi request reprint Sentinel lymphonodectomy does not increase the risk of loco-regional cutaneous metastases of malignant melanomas
    L Kretschmer
    Department of Dermatology, Georg August University of Gottingen, v Siebold Str 3, D 37075, Gottingen, Germany
    Eur J Cancer 41:531-8. 2005
    ..However, the overall in-transit probability is not increased after SLNE...
  21. ncbi request reprint Hybrid cell vaccination in metastatic melanoma: clinical and immunologic results of a phase I/II study
    Holger A Haenssle
    Department of Dermatology, Georg August University Goettingen, Germany
    J Immunother 27:147-55. 2004
    ..No unequivocal beneficial effects of the used CFP vaccine could be demonstrated...
  22. ncbi request reprint Locoregional cutaneous metastasis in patients with therapeutic lymph node dissection for malignant melanoma: risk factors and prognostic impact
    L Kretschmer
    Abteilung für Dermatologie und Venerologie, Georg August Universitat Gottingen, Germany
    Melanoma Res 12:499-504. 2002
    ..In the subpopulation of patients with lymph node metastasis, Breslow thickness predicts the probability of additional locoregional cutaneous metastasis...
  23. ncbi request reprint Low-dose gemcitabine efficacious in three patients with tumor-stage mycosis fungoides
    Timo Buhl
    Department of Dermatology and Venereology, Georg August University, Gottingen, Germany
    Clin Lymphoma Myeloma 9:E21-4. 2009
    ..All patients experienced excellent improvement with 250 mg/m2 gemcitabine weekly, a low-dose regimen that is predicted to be less toxic compared with standard-dose gemcitabine...
  24. ncbi request reprint Inefficacy of vindesine monotherapy in advanced stage IV malignant melanoma patients previously treated with other chemotherapeutic agents
    S Emmert
    Department of Dermatology, Georg August University, Goettingen, Germany
    Melanoma Res 13:299-302. 2003
    ..We conclude that vindesine monotherapy is ineffective in stage IV melanoma patients previously treated with other chemotherapeutic agents...
  25. ncbi request reprint [Paratibial fasciotomy for postthrombotic leg ulcer using Vollmars fasciotome]
    Christiane Grattenthaler
    Abteilung Dermatologie und Venerologie, Georg August Universitat Gottingen, Germany
    J Dtsch Dermatol Ges 5:1144-5. 2007
  26. ncbi request reprint Temozolomide in combination with interferon-alfa versus temozolomide alone in patients with advanced metastatic melanoma: a randomized, phase III, multicenter study from the Dermatologic Cooperative Oncology Group
    Roland Kaufmann
    Department of Dermatology, J W Goethe University, Frankfurt am Main, Germany
    J Clin Oncol 23:9001-7. 2005
    ....
  27. ncbi request reprint [Bizarrely patterned erythema and papules in a 39-year-old man. Lymphangiosis carcinomatosa as the chief symptom of disseminated metastatic breast carcinoma in a man]
    S Emmert
    Abteilung Dermatologie und Venerologie, Georg August Universitat Gottingen, Germany
    Hautarzt 53:495-8. 2002
  28. ncbi request reprint Schimmelpenning-Feuerstein-Mims syndrome with hypophosphatemic rickets
    M Zutt
    Department of Dermatology, University of Gottingen, Gottingen, Germany
    Dermatology 207:72-6. 2003
    ....
  29. ncbi request reprint Sentinel lymph node status is the most important prognostic factor for thick (> or = 4 mm) melanomas
    Ralf Gutzmer
    Department of Dermatology and Venereology, Skin Tumor Center Hannover HTZH, Hannover Medical School, Hannover, Germany
    J Dtsch Dermatol Ges 6:198-203. 2008
    ..The value of the status of the sentinel lymph node (SLN) in patients with thick melanomas (Breslow thickness > or = 4 mm) is controversial...
  30. ncbi request reprint Research supports the view that sentinel node biopsy is the standard of care in high-risk primary melanoma
    Lutz Kretschmer
    J Clin Oncol 24:2965-6; author reply 2966-7. 2006
  31. ncbi request reprint Sentinel-node technique will change the design of clinical trials in malignant melanoma
    Lutz Kretschmer
    J Clin Oncol 20:2208; author reply 2209-10. 2002