Research Topics
Genomes and Genes | J KremerskothenSummaryCountry: Germany Publications
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Detail Information
Publications
Characterization of KIBRA, a novel WW domain-containing proteinJoachim Kremerskothen
Department for Experimental Tumorbiology, University Muenster, Badestrasse 9, D 48149 Muenster, Germany
Biochem Biophys Res Commun 300:862-7. 2003..Transient transfection of monkey kidney cells with constructs encoding Myc-tagged KIBRA displayed a cytoplasmic localization and a perinuclear enrichment of the protein...
Synaptopodin, a molecule involved in the formation of the dendritic spine apparatus, is a dual actin/alpha-actinin binding proteinJoachim Kremerskothen
Department for Experimental Tumorbiology, University of Muenster, Badestrasse 9, D 48149 Muenster, Germany
J Neurochem 92:597-606. 2005....
Identification and characterization of Iporin as a novel interaction partner for rab1Michael Bayer
UKM Muenster, Albert Schweitzer Str 33, D 48149 Muenster, Germany
BMC Cell Biol 6:15. 2005..To date p115, GM130, golgin-84 and MICAL have been identified as direct interacting partners. Together with rab1, these molecules are components of a protein complex, which mediates and regulates intracellular vesicle transport...
Human activity-regulated cytoskeleton-associated gene (ARC) maps to chromosome 8q24J Kremerskothen
Department of Experimental Tumorbiology, University Muenster, Germany
Chromosome Res 8:655. 2000
Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoringJoachim Kremerskothen
Department for Experimental Tumorbiology, University Muenster, Badestrasse 9, D 48149 Muenster, Germany
J Neurochem 96:1659-66. 2006..Its nuclear localization capacity further points to a function in retrograde signaling from the synapse to the nucleus...
Brain-specific splicing of alpha-actinin 1 (ACTN1) mRNAJoachim Kremerskothen
Department for Experimental Tumorbiology, University Muenster, Badestrasse 9, Germany
Biochem Biophys Res Commun 295:678-81. 2002..In situ hybridization analysis revealed that BS expression was highest in neurons of the hippocampus, cortex, and caudate putamen while the cerebellum and other subcortical structures showed only weak labeling...
Insulin-induced expression of the activity-regulated cytoskeleton-associated gene (ARC) in human neuroblastoma cells requires p21(ras), mitogen-activated protein kinase/extracellular regulated kinase and src tyrosine kinases but is protein kinase C-indepeJoachim Kremerskothen
Department for Experimental Tumor Biology, University Muenster, Badestrasse 9, 48149 Muenster, Germany
Neurosci Lett 321:153-6. 2002..Our data indicated for the first time a correlation of the insulin-controlled signal cascade and the induction of synaptic plasticity-associated immediate early genes...
Birth of a gene: locus of neuronal BC200 snmRNA in three prosimians and human BC200 pseudogenes as archives of change in the Anthropoidea lineageV Y Kuryshev
Institute of Experimental Pathology Molecular Neurobiology, ZMBE, University of Munster, Von Esmarch Str 56, Munster, D 48149, Germany
J Mol Biol 309:1049-66. 2001....
KIBRA is a novel substrate for protein kinase CzetaKatrin Büther
Department for Experimental Tumorbiology, University Muenster, Badestrasse 9, D 48149 Muenster, Germany
Biochem Biophys Res Commun 317:703-7. 2004..Our studies presented here revealed that KIBRA is a novel substrate for PKCzeta and suggest that PKCzeta phosphorylation may regulate the cellular function of KIBRA...
Muscarinic acetylcholine receptor stimulation induces expression of the activity-regulated cytoskeleton-associated gene (ARC)Iskender Teber
Department for Experimental Tumorbiology, Institute for Neurobiology, University Muenster, Badestrasse 9, D 48149 Muenster, Germany
Brain Res Mol Brain Res 121:131-6. 2004..Our data suggest, for the first time, that a correlation exists among mAChR-controlled signal cascades, the induction of the effector immediate early gene ARC and synaptic plasticity...
SYNCRIP, a component of dendritically localized mRNPs, binds to the translation regulator BC200 RNAKerstin Duning
Department for Experimental Tumorbiology, University Muenster, Muenster, Germany
J Neurochem 105:351-9. 2008..Thus, SYNCRIP may recruit BC200 RNA into mRNA transport complexes involved in the regulation of localized translation in dendrites...
Poly(A)-binding protein is associated with neuronal BC1 and BC200 ribonucleoprotein particlesRavi Muddashetty
Institute of Experimental Pathology, ZMBE, , Von Esmarch Str 56, D 48149, , Germany
J Mol Biol 321:433-45. 2002..These findings lend support to the hypothesis that the BC1 and BC200 RNPs are involved in protein translation in neuronal dendrites...
SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartmentColin J Traer
The Henry Wellcome Integrated Signalling Laboratories, Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK
Nat Cell Biol 9:1370-80. 2007..Finally, these data suggest that by associating with molecular motors, SNX-BAR proteins may coordinate sorting with carrier transport between donor and recipient membranes...
Characterization of KIAA0513, a novel signaling molecule that interacts with modulators of neuroplasticity, apoptosis, and the cytoskeletonTara L Lauriat
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
Brain Res 1121:1-11. 2006..Therefore, KIAA0513 is likely to be involved in signaling pathways related to these processes...
Essential role of KIBRA in co-activator function of dynein light chain 1 in mammalian cellsSuresh K Rayala
Department of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Biol Chem 281:19092-9. 2006..Together these findings indicate that DLC1-KIBRA interaction is essential for ER transactivation in breast cancer cells...
Rab6 interacts with the mint3 adaptor proteinIskender Teber
Department of Experimental Tumor Biology, , D-48149 Germany
Biol Chem 386:671-7. 2005..Density gradient centrifugation of cytosolic extracts confirms a common distribution of these three proteins. Our data suggest that mint3 links Rab6A to APP traffic...
Interaction of rat poly(A)-binding protein with poly(A)- and non-poly(A) sequences is preferentially mediated by RNA recognition motifs 3+4Carola Mullin
Department for Cell Biochemistry and Clinical Neurobiology, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
FEBS Lett 576:437-41. 2004..An optimal interaction with both poly(A)- and non-poly(A) sequences is only achieved by full-size PABP...
KIBRA modulates directional migration of podocytesKerstin Duning
Medizinische Klinik und Poliklinik D, Universitatsklinikum Munster, Munster, Germany
J Am Soc Nephrol 19:1891-903. 2008..Stable knockdown of KIBRA in immortalized podocytes impaired directed cell migration, suggesting that KIBRA modulates the motility of podocytes by linking polarity proteins and cytoskeleton-associated protein complexes...
