Mariusz Pawel Kowalewski

Summary

Country: Germany

Publications

  1. doi request reprint Uterine and placental distribution of selected extracellular matrix (ECM) components in the dog.
    Felix R Graubner
    F Graubner, University of Zurich, Institute of Veterinary Anatomy, Winterthurerstrasse 260, Vetsuisse Faculty, Zurich, Switzerland
    Reproduction . 2018
  2. doi request reprint Transcriptome analysis reveals differences in mechanisms regulating cessation of luteal function in pregnant and non-pregnant dogs
    Sophie Zatta
    Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057, Zurich, Switzerland
    BMC Genomics 18:757. 2017
  3. doi request reprint Formation of the early canine CL and the role of prostaglandin E2 (PGE2) in regulation of its function: an in vivo approach
    M P Kowalewski
    Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland Electronic address
    Theriogenology 83:1038-47. 2015
  4. doi request reprint The role of hypoxia and HIF1α in the regulation of STAR-mediated steroidogenesis in granulosa cells
    Mariusz Pawel Kowalewski
    Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland Electronic address
    Mol Cell Endocrinol 401:35-44. 2015
  5. pmc Steroidogenic capacity of the placenta as a supplemental source of progesterone during pregnancy in domestic cats
    Marta J Siemieniuch
    Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Olsztyn 10 747, Tuwima St, 10, Poland
    Reprod Biol Endocrinol 10:89. 2012
  6. doi request reprint Endocrine and molecular control of luteal and placental function in dogs: a review
    M P Kowalewski
    Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Reprod Domest Anim 47:19-24. 2012
  7. ncbi request reprint Canine prostaglandin F2alpha receptor (FP) and prostaglandin F2alpha synthase (PGFS): molecular cloning and expression in the corpus luteum
    Mariusz Pawel Kowalewski
    Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Justus Liebig University Giessen, Frankfurter Strasse 106, 35392 Giessen, Germany
    Anim Reprod Sci 107:161-75. 2008
  8. doi request reprint Canine prostaglandin E2 synthase (PGES) and its receptors (EP2 and EP4): expression in the corpus luteum during dioestrus
    Mariusz Pawel Kowalewski
    Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Justus Liebig University Giessen, Giessen, Germany
    Anim Reprod Sci 109:319-29. 2008
  9. doi request reprint Time related changes in luteal prostaglandin synthesis and steroidogenic capacity during pregnancy, normal and antiprogestin induced luteolysis in the bitch
    Mariusz Pawel Kowalewski
    Clinic for Obstetrics, Gynecology und Andrology of Large and Small Animals, Justus Liebig University Giessen, Germany
    Anim Reprod Sci 116:129-38. 2009
  10. doi request reprint Canine placenta: a source of prepartal prostaglandins during normal and antiprogestin-induced parturition
    Mariusz Pawel Kowalewski
    Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Justus Liebig University Giessen, 35392 Giessen, Germany
    Reproduction 139:655-64. 2010

Collaborators

Detail Information

Publications12

  1. doi request reprint Uterine and placental distribution of selected extracellular matrix (ECM) components in the dog.
    Felix R Graubner
    F Graubner, University of Zurich, Institute of Veterinary Anatomy, Winterthurerstrasse 260, Vetsuisse Faculty, Zurich, Switzerland
    Reproduction . 2018
    ..g., in humans in which Placenta accreta appears to share several similarities with canine subinvolution of placental sites (SIPS)...
  2. doi request reprint Transcriptome analysis reveals differences in mechanisms regulating cessation of luteal function in pregnant and non-pregnant dogs
    Sophie Zatta
    Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057, Zurich, Switzerland
    BMC Genomics 18:757. 2017
    ..Therefore, here, next-generation sequencing (RNA-Seq) was performed on CL from the late luteal phase and compared with normally luteolyzing CL collected at the prepartum P4 decrease...
  3. doi request reprint Formation of the early canine CL and the role of prostaglandin E2 (PGE2) in regulation of its function: an in vivo approach
    M P Kowalewski
    Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland Electronic address
    Theriogenology 83:1038-47. 2015
    ..Additionally, the possibility of an indirect effect on PRL function arises from the increased prolactin receptor expression in response to PGE2 treatment in canine lutein cells observed in vitro. ..
  4. doi request reprint The role of hypoxia and HIF1α in the regulation of STAR-mediated steroidogenesis in granulosa cells
    Mariusz Pawel Kowalewski
    Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland Electronic address
    Mol Cell Endocrinol 401:35-44. 2015
    ..HIF1α appears to be a positive regulator of basal and stimulated STAR-expression, which under partial hypoxia is capable of increasing the steroidogenic capacity of granulosa cells. ..
  5. pmc Steroidogenic capacity of the placenta as a supplemental source of progesterone during pregnancy in domestic cats
    Marta J Siemieniuch
    Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Olsztyn 10 747, Tuwima St, 10, Poland
    Reprod Biol Endocrinol 10:89. 2012
    ....
  6. doi request reprint Endocrine and molecular control of luteal and placental function in dogs: a review
    M P Kowalewski
    Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Reprod Domest Anim 47:19-24. 2012
    ..This is in contrast to pregnant dogs in which prepartum luteolysis seems to be an active process of CL destruction by PGF2α of utero/placental origin targeting the luteal PGF2α-receptor...
  7. ncbi request reprint Canine prostaglandin F2alpha receptor (FP) and prostaglandin F2alpha synthase (PGFS): molecular cloning and expression in the corpus luteum
    Mariusz Pawel Kowalewski
    Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Justus Liebig University Giessen, Frankfurter Strasse 106, 35392 Giessen, Germany
    Anim Reprod Sci 107:161-75. 2008
    ..These data suggest that luteal regression in non-pregnant bitches is not modulated by PGF2alpha. However, the FP seems to be constitutionally expressed, explaining the receptivity of canine CL to exogenous PGF2alpha...
  8. doi request reprint Canine prostaglandin E2 synthase (PGES) and its receptors (EP2 and EP4): expression in the corpus luteum during dioestrus
    Mariusz Pawel Kowalewski
    Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Justus Liebig University Giessen, Giessen, Germany
    Anim Reprod Sci 109:319-29. 2008
    ..In conclusion, our data suggest that in the dog PGE2 of luteal origin acts by autocrine mechanism as a luteotropic factor through its EP2 and EP4 receptors during the phase of CL-formation...
  9. doi request reprint Time related changes in luteal prostaglandin synthesis and steroidogenic capacity during pregnancy, normal and antiprogestin induced luteolysis in the bitch
    Mariusz Pawel Kowalewski
    Clinic for Obstetrics, Gynecology und Andrology of Large and Small Animals, Justus Liebig University Giessen, Germany
    Anim Reprod Sci 116:129-38. 2009
    ..On the other hand induction of luteolysis by the PR blocker Aglepristone points to a role of luteal P4 as an autocrine factor in a positive loop feedback system controlling the availability of P4, StAR and 3betaHSD...
  10. doi request reprint Canine placenta: a source of prepartal prostaglandins during normal and antiprogestin-induced parturition
    Mariusz Pawel Kowalewski
    Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Justus Liebig University Giessen, 35392 Giessen, Germany
    Reproduction 139:655-64. 2010
    ....
  11. doi request reprint Expression and functional implications of peroxisome proliferator-activated receptor gamma (PPARγ) in canine reproductive tissues during normal pregnancy and parturition and at antiprogestin induced abortion
    Mariusz Pawel Kowalewski
    Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland
    Theriogenology 75:877-86. 2011
    ..Treatment with Aglepristone led to downregulation of PPARγ in either compartment, implying the functional interrelationship with progesterone receptor...
  12. ncbi request reprint Expression of cyclooxygenase 1 and 2 in the canine corpus luteum during diestrus
    Mariusz Pawel Kowalewski
    Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Justus Liebig University Giessen, Frankfurter Strasse 106, D 35392 Giessen, Germany
    Theriogenology 66:1423-30. 2006
    ..These data suggested that increased expression of Cox2 is associated with luteal growth and development and not luteal regression. Furthermore, the expression of Cox1 more likely reflected activity of a housekeeping gene...