Lars Komorowski

Summary

Country: Germany

Publications

  1. Komorowski L, Teegen B, Probst C, Aulinger Stöcker K, Sina C, Fellermann K, et al. Autoantibodies against exocrine pancreas in Crohn's disease are directed against two antigens: the glycoproteins CUZD1 and GP2. J Crohns Colitis. 2013;7:780-90 pubmed publisher
    ..The concordant reactivities of the different platforms can be regarded as a proof for the authenticity of the two identified autoantigens. ..
  2. Edmondson D, Prabhakaran S, Norris S, Ullmann A, Piesman J, Dolan M, et al. Enhanced Protective Immunogenicity of Homodimeric Borrelia burgdorferi Outer Surface Protein C. Clin Vaccine Immunol. 2017;24: pubmed publisher
    ..These studies suggest that this dimeric OspC presents distinctive epitopes that generate antibodies protective against B. burgdorferi infection and could be a useful vaccine component. ..
  3. Jarius S, Scharf M, Begemann N, Stöcker W, Probst C, Serysheva I, et al. Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia. J Neuroinflammation. 2014;11:206 pubmed publisher
    ..Our findings suggest a role of autoimmunity against ITPR1 in the pathogenesis of autoimmune cerebellitis and extend the panel of diagnostic markers for this disease. ..
  4. Scharf M, Miske R, Heidenreich F, Giess R, Landwehr P, Blöcker I, et al. Neuronal Na+/K+ ATPase is an autoantibody target in paraneoplastic neurologic syndrome. Neurology. 2015;84:1673-9 pubmed publisher
    ..Although the autoantibodies are unlikely to be pathogenic, they are likely to be rare biomarkers for the apparently paraneoplastic neurologic syndrome or for the tumor itself. ..
  5. Hahn S, Trendelenburg G, Scharf M, Denno Y, Brakopp S, Teegen B, et al. Identification of the flotillin-1/2 heterocomplex as a target of autoantibodies in bona fide multiple sclerosis. J Neuroinflammation. 2017;14:123 pubmed publisher
    ..Autoantibodies against the flotillin-1/2 heterocomplex, a peripheral membrane protein that is involved in axon outgrowth and regeneration of the optic nerve, are present in 1-2% of patients with bona fide MS. ..
  6. Höltje M, Mertens R, Schou M, Saether S, Kochova E, Jarius S, et al. Synapsin-antibodies in psychiatric and neurological disorders: Prevalence and clinical findings. Brain Behav Immun. 2017;66:125-134 pubmed publisher
  7. Hanke K, Brückner C, Dähnrich C, Huscher D, Komorowski L, Meyer W, et al. Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients. Arthritis Res Ther. 2009;11:R22 pubmed publisher
    ..They are directed mainly to the PM/Scl-75 antigen. Consequently, the detection of anti-PM/Scl antibodies by tests based only on PM/Scl-100 as an antigen source may miss a relevant number of SSc patients positive for these antibodies. ..