A F Kolb

Summary

Country: Germany

Publications

  1. ncbi Identification of residues critical for the human coronavirus 229E receptor function of human aminopeptidase N
    A F Kolb
    Institute of Virology and Immunology, University of Wurzburg, Germany
    J Gen Virol 78:2795-802. 1997
  2. ncbi Molecular analysis of the coronavirus-receptor function of aminopeptidase N
    A F Kolb
    Institute of Virology and Immunology, University of Wurzburg, Germany
    Adv Exp Med Biol 440:61-7. 1998
  3. ncbi Characterization of determinants involved in the feline infectious peritonitis virus receptor function of feline aminopeptidase N
    A Hegyi
    Institute of Virology and Immunology, University of Wurzburg, Germany
    J Gen Virol 79:1387-91. 1998
  4. ncbi Characterization of functional domains in the human coronavirus HCV 229E receptor
    A F Kolb
    Institute of Virology and Immunology, University of Wurzburg, Germany
    J Gen Virol 77:2515-21. 1996
  5. ncbi Genomic targeting of a bicistronic DNA fragment by Cre-mediated site-specific recombination
    A F Kolb
    Institute of Virology and Immunology, University of Wurzburg, Germany
    Gene 203:209-16. 1997
  6. ncbi A functional eukaryotic promoter is contained within the first intron of the hGH-N coding region
    A F Kolb
    Institute of Virology and Immunology, University of Wurzburg, Germany
    Biochem Biophys Res Commun 247:332-7. 1998

Collaborators

Detail Information

Publications6

  1. ncbi Identification of residues critical for the human coronavirus 229E receptor function of human aminopeptidase N
    A F Kolb
    Institute of Virology and Immunology, University of Wurzburg, Germany
    J Gen Virol 78:2795-802. 1997
    ..These changes were sufficient to convert porcine APN into a functional receptor for HCV 229E and thus define a small number of residues that are critically important for the HCV 229E receptor function of human APN...
  2. ncbi Molecular analysis of the coronavirus-receptor function of aminopeptidase N
    A F Kolb
    Institute of Virology and Immunology, University of Wurzburg, Germany
    Adv Exp Med Biol 440:61-7. 1998
    ..A further analysis of the mapped amino acid segments by site directed mutagenesis revealed that a short stretch of 8 amino acids in the hAPN protein plays a decisive role in mediating HCV 229E reception...
  3. ncbi Characterization of determinants involved in the feline infectious peritonitis virus receptor function of feline aminopeptidase N
    A Hegyi
    Institute of Virology and Immunology, University of Wurzburg, Germany
    J Gen Virol 79:1387-91. 1998
    ..This is surprising as neither human nor porcine APN by themselves mediate FIPV infection. These results suggest that different determinants in the APN protein are involved in mediating the coronavirus receptor function...
  4. ncbi Characterization of functional domains in the human coronavirus HCV 229E receptor
    A F Kolb
    Institute of Virology and Immunology, University of Wurzburg, Germany
    J Gen Virol 77:2515-21. 1996
    ..We conclude that although both viruses use a homologous receptor protein, different regions of the protein are required to mediate susceptibility to infection with HCV 229E and TGEV...
  5. ncbi Genomic targeting of a bicistronic DNA fragment by Cre-mediated site-specific recombination
    A F Kolb
    Institute of Virology and Immunology, University of Wurzburg, Germany
    Gene 203:209-16. 1997
    ..This methodology will be particularly useful for genomic targeting experiments in transgenic animals...
  6. ncbi A functional eukaryotic promoter is contained within the first intron of the hGH-N coding region
    A F Kolb
    Institute of Virology and Immunology, University of Wurzburg, Germany
    Biochem Biophys Res Commun 247:332-7. 1998
    ..This internal hGH-N promoter can interfere with the transcriptional control elements of a promoter linked to the hGH-N coding region and thereby complicate the interpretation of data obtained with hGH-N as a reporter gene...