Sarah Koenig

Summary

Country: Germany

Publications

  1. pmc Increased growth of colorectal liver metastasis following partial hepatectomy
    P Krause
    Department of General and Visceral Surgery, University Medical Centre, Georg August University Goettingen, Robert Koch Strasse 40, 37075, Goettingen, Germany
    Clin Exp Metastasis 30:681-93. 2013
  2. doi request reprint Regional transient portal ischemia and irradiation as preparative regimen for hepatocyte transplantation
    S Koenig
    Department of General and Visceral Surgery, University Medical Centre Goettingen, Goettingen, Germany
    Cell Transplant 20:303-11. 2011
  3. doi request reprint Irradiation as preparative regimen for hepatocyte transplantation causes prolonged cell cycle block
    Sarah Koenig
    University Hospital Goettingen, Department of General and Visceral Surgery, Robert Koch Strasse 40, 37099 Goettingen, Germany
    Int J Radiat Biol 84:285-98. 2008
  4. ncbi request reprint Noninvasive imaging of liver repopulation following hepatocyte transplantation
    Sarah Koenig
    Department of General and Visceral Surgery, University Hospital Goettingen, Goettingen, Germany
    Cell Transplant 18:69-78. 2009
  5. ncbi request reprint External-beam radiotherapy as preparative regimen for hepatocyte transplantation after partial hepatectomy
    Hans Christiansen
    Department of Radiotherapy, University Hospital Goettingen, Goettingen, Germany
    Int J Radiat Oncol Biol Phys 65:509-16. 2006
  6. pmc Liver sinusoidal endothelial and biliary cell repopulation following irradiation and partial hepatectomy
    Petra Krause
    Department of General Surgery, University Medical Centre Goettingen, Robert Koch Strasse 40, Goettingen, Germany
    World J Gastroenterol 16:3928-35. 2010
  7. doi request reprint Fractionated external beam radiotherapy as a suitable preparative regimen for hepatocyte transplantation after partial hepatectomy
    Petra Krause
    Department of General and Visceral Surgery, University Medical Centre Goettingen, Goettingen, Germany
    Int J Radiat Oncol Biol Phys 80:1214-9. 2011
  8. ncbi request reprint Zonal hierarchy of differentiation markers and nestin expression during oval cell mediated rat liver regeneration
    Sarah Koenig
    Department of General Surgery, University Hospital, Robert Koch Strasse 40, 37099 Goettingen, Germany
    Histochem Cell Biol 126:723-34. 2006
  9. ncbi request reprint Zonal expression of hepatocytic marker enzymes during liver repopulation
    Sarah Koenig
    Department of General Surgery, Faculty of Medicine and University Hospital, Georg August University Goettingen, 37099, Goettingen, Germany
    Histochem Cell Biol 128:105-14. 2007
  10. doi request reprint Maintaining hepatocyte differentiation in vitro through co-culture with hepatic stellate cells
    Petra Krause
    Department of General Surgery, Georg August University Goettingen, Goettingen, Germany
    In Vitro Cell Dev Biol Anim 45:205-12. 2009

Collaborators

Detail Information

Publications14

  1. pmc Increased growth of colorectal liver metastasis following partial hepatectomy
    P Krause
    Department of General and Visceral Surgery, University Medical Centre, Georg August University Goettingen, Robert Koch Strasse 40, 37075, Goettingen, Germany
    Clin Exp Metastasis 30:681-93. 2013
    ..Future investigations should focus on the inhibition of cell cycle (i.e. systemic therapy strategies, irradiation) to hinder liver regeneration and therefore restrain tumor growth...
  2. doi request reprint Regional transient portal ischemia and irradiation as preparative regimen for hepatocyte transplantation
    S Koenig
    Department of General and Visceral Surgery, University Medical Centre Goettingen, Goettingen, Germany
    Cell Transplant 20:303-11. 2011
    ..The method described clearly has potential for clinical application...
  3. doi request reprint Irradiation as preparative regimen for hepatocyte transplantation causes prolonged cell cycle block
    Sarah Koenig
    University Hospital Goettingen, Department of General and Visceral Surgery, Robert Koch Strasse 40, 37099 Goettingen, Germany
    Int J Radiat Biol 84:285-98. 2008
    ..We investigated the changes in the liver induced by IR explaining the loss of reproductive integrity in endogenous hepatocytes...
  4. ncbi request reprint Noninvasive imaging of liver repopulation following hepatocyte transplantation
    Sarah Koenig
    Department of General and Visceral Surgery, University Hospital Goettingen, Goettingen, Germany
    Cell Transplant 18:69-78. 2009
    ..Our results provide a basis for the future development of clinical protocols for suitable fluorescent dyes and imaging technologies...
  5. ncbi request reprint External-beam radiotherapy as preparative regimen for hepatocyte transplantation after partial hepatectomy
    Hans Christiansen
    Department of Radiotherapy, University Hospital Goettingen, Goettingen, Germany
    Int J Radiat Oncol Biol Phys 65:509-16. 2006
    ..This study describes a novel selective external-beam irradiation technique as a preparative regimen for hepatocyte transplantation...
  6. pmc Liver sinusoidal endothelial and biliary cell repopulation following irradiation and partial hepatectomy
    Petra Krause
    Department of General Surgery, University Medical Centre Goettingen, Robert Koch Strasse 40, Goettingen, Germany
    World J Gastroenterol 16:3928-35. 2010
    ..To investigate whether irradiation (IR) and partial hepatectomy (PH) may prepare the host liver for non-parenchymal cell (NPC) transplantation...
  7. doi request reprint Fractionated external beam radiotherapy as a suitable preparative regimen for hepatocyte transplantation after partial hepatectomy
    Petra Krause
    Department of General and Visceral Surgery, University Medical Centre Goettingen, Goettingen, Germany
    Int J Radiat Oncol Biol Phys 80:1214-9. 2011
    ..Herein, we tested lower radiation doses and fractionated protocols, which would be applicable in clinical use...
  8. ncbi request reprint Zonal hierarchy of differentiation markers and nestin expression during oval cell mediated rat liver regeneration
    Sarah Koenig
    Department of General Surgery, University Hospital, Robert Koch Strasse 40, 37099 Goettingen, Germany
    Histochem Cell Biol 126:723-34. 2006
    ....
  9. ncbi request reprint Zonal expression of hepatocytic marker enzymes during liver repopulation
    Sarah Koenig
    Department of General Surgery, Faculty of Medicine and University Hospital, Georg August University Goettingen, 37099, Goettingen, Germany
    Histochem Cell Biol 128:105-14. 2007
    ..These results indicate the high degree of plasticity of gene expression in hepatocytes subjected to a change in microenvironment...
  10. doi request reprint Maintaining hepatocyte differentiation in vitro through co-culture with hepatic stellate cells
    Petra Krause
    Department of General Surgery, Georg August University Goettingen, Goettingen, Germany
    In Vitro Cell Dev Biol Anim 45:205-12. 2009
    ..HSCs maintain hepatocyte function and structure through preferentially cell-bound signalling and transfer of lipids...
  11. pmc The plasminogen activator inhibitor system in colon cancer cell lines is influenced by the CO2 pneumoperitoneum
    Petra Krause
    Department of General and Visceral Surgery, University Medical Centre Goettingen, Robert Koch Str 40, 37075 Goettingen, Germany
    Int J Colorectal Dis 26:37-43. 2011
    ..So far, the direct influence of CO(2) pneumoperitoneum on the invasiveness and metastatic capabilities of colon cancer cells remains unclear. We therefore evaluated transcripts of the uPA system...
  12. ncbi request reprint The expression of mesenchymal, neural and haematopoietic stem cell markers in adult hepatocytes proliferating in vitro
    Sarah Koenig
    Department of General Surgery, Georg August University Goettingen, Germany
    J Hepatol 44:1115-24. 2006
    ..Cultured adult hepatocytes may be stimulated into clonal expansion. We raise the question whether adult hepatocytes proliferating in vitro recapitulate the early process of hepatic development...
  13. ncbi request reprint Functional characterization of serum-free cultured rat hepatocytes for downstream transplantation applications
    Hendryk Aurich
    Klinik und Poliklinik für Innere Medizin I, Martin Luther Universitaet Halle Wittenberg, Germany
    Cell Transplant 14:497-506. 2005
    ..The loss of hepatocyte-specific functions during culture may be restored after transplantation, suggesting that the proper physiological environment is required to maintain the differentiated phenotype...
  14. ncbi request reprint Liver repopulation after hepatocellular transplantation: integration and interaction of transplanted hepatocytes in the host
    Sarah Koenig
    Department of General Surgery, Georg August University Goettingen, 37099 Germany
    Cell Transplant 14:31-40. 2005
    ..FACS analysis reveals an accurate method to determine quantitatively the extent of liver repopulation...