Research Topics
Species | Sarah KoenigSummaryCountry: Germany Publications
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Detail Information
Publications
Irradiation as preparative regimen for hepatocyte transplantation causes prolonged cell cycle blockSarah Koenig
University Hospital Goettingen, Department of General and Visceral Surgery, Robert Koch Strasse 40, 37099 Goettingen, Germany
Int J Radiat Biol 84:285-98. 2008..We investigated the changes in the liver induced by IR explaining the loss of reproductive integrity in endogenous hepatocytes...
Regional transient portal ischemia and irradiation as preparative regimen for hepatocyte transplantationS Koenig
Department of General and Visceral Surgery, University Medical Centre Goettingen, Goettingen, Germany
Cell Transplant 20:303-11. 2011..The method described clearly has potential for clinical application...
Noninvasive imaging of liver repopulation following hepatocyte transplantationSarah Koenig
Department of General and Visceral Surgery, University Hospital Goettingen, Goettingen, Germany
Cell Transplant 18:69-78. 2009..Our results provide a basis for the future development of clinical protocols for suitable fluorescent dyes and imaging technologies...
Liver sinusoidal endothelial and biliary cell repopulation following irradiation and partial hepatectomyPetra Krause
Department of General Surgery, University Medical Centre Goettingen, Robert Koch Strasse 40, Goettingen, Germany
World J Gastroenterol 16:3928-35. 2010..To investigate whether irradiation (IR) and partial hepatectomy (PH) may prepare the host liver for non-parenchymal cell (NPC) transplantation...
Fractionated external beam radiotherapy as a suitable preparative regimen for hepatocyte transplantation after partial hepatectomyPetra Krause
Department of General and Visceral Surgery, University Medical Centre Goettingen, Goettingen, Germany
Int J Radiat Oncol Biol Phys 80:1214-9. 2011..Herein, we tested lower radiation doses and fractionated protocols, which would be applicable in clinical use...
External-beam radiotherapy as preparative regimen for hepatocyte transplantation after partial hepatectomyHans Christiansen
Department of Radiotherapy, University Hospital Goettingen, Goettingen, Germany
Int J Radiat Oncol Biol Phys 65:509-16. 2006..This study describes a novel selective external-beam irradiation technique as a preparative regimen for hepatocyte transplantation...
Zonal expression of hepatocytic marker enzymes during liver repopulationSarah Koenig
Department of General Surgery, Faculty of Medicine and University Hospital, Georg August University Goettingen, 37099, Goettingen, Germany
Histochem Cell Biol 128:105-14. 2007..These results indicate the high degree of plasticity of gene expression in hepatocytes subjected to a change in microenvironment...
Zonal hierarchy of differentiation markers and nestin expression during oval cell mediated rat liver regenerationSarah Koenig
Department of General Surgery, University Hospital, Robert Koch Strasse 40, 37099 Goettingen, Germany
Histochem Cell Biol 126:723-34. 2006....
Maintaining hepatocyte differentiation in vitro through co-culture with hepatic stellate cellsPetra Krause
Department of General Surgery, Georg August University Goettingen, Goettingen, Germany
In Vitro Cell Dev Biol Anim 45:205-12. 2009..HSCs maintain hepatocyte function and structure through preferentially cell-bound signalling and transfer of lipids...
The plasminogen activator inhibitor system in colon cancer cell lines is influenced by the CO2 pneumoperitoneumPetra Krause
Department of General and Visceral Surgery, University Medical Centre Goettingen, Robert Koch Str 40, 37075 Goettingen, Germany
Int J Colorectal Dis 26:37-43. 2011..So far, the direct influence of CO(2) pneumoperitoneum on the invasiveness and metastatic capabilities of colon cancer cells remains unclear. We therefore evaluated transcripts of the uPA system...
Functional characterization of serum-free cultured rat hepatocytes for downstream transplantation applicationsHendryk Aurich
Klinik und Poliklinik für Innere Medizin I, Martin Luther Universitaet Halle Wittenberg, Germany
Cell Transplant 14:497-506. 2005..The loss of hepatocyte-specific functions during culture may be restored after transplantation, suggesting that the proper physiological environment is required to maintain the differentiated phenotype...
Liver repopulation after hepatocellular transplantation: integration and interaction of transplanted hepatocytes in the hostSarah Koenig
Department of General Surgery, Georg August University Goettingen, 37099 Germany
Cell Transplant 14:31-40. 2005..FACS analysis reveals an accurate method to determine quantitatively the extent of liver repopulation...
The expression of mesenchymal, neural and haematopoietic stem cell markers in adult hepatocytes proliferating in vitroSarah Koenig
Department of General Surgery, Georg August University Goettingen, Germany
J Hepatol 44:1115-24. 2006..Cultured adult hepatocytes may be stimulated into clonal expansion. We raise the question whether adult hepatocytes proliferating in vitro recapitulate the early process of hepatic development...
