Ingmar Königsrainer

Summary

Country: Germany

Publications

  1. doi request reprint Do patient- and tumor-related factors predict the peritoneal spread of pancreatic adenocarcinoma?
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, University of Tübingen Comprehensive Cancer Center, Hoppe Seyler Strasse 3, 72076, Tubingen, Germany
    Surg Today 44:260-3. 2014
  2. doi request reprint Risk factors for recurrence following complete cytoreductive surgery and HIPEC in colorectal cancer-derived peritoneal surface malignancies
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, University of Tubingen, Hoppe Seyler Strasse 3, 72076, Tubingen, Germany
    Langenbecks Arch Surg 398:745-9. 2013
  3. pmc Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: where are we?
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Tubingen University Hospital, D 72076 Tubingen, Germany Germany
    World J Gastroenterol 18:5317-20. 2012
  4. pmc Selection criteria for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in gastric cancer
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Tubingen University Hospital, 72076 Tubingen, Germany
    World J Gastroenterol 17:4153-6. 2011
  5. pmc Experience after 100 patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
    Ingmar Königsrainer
    Department of Surgery, University of Tubingen, Hoppe Seyler Strasse 3, D 72076 Tubingen, Germany
    World J Gastroenterol 18:2061-6. 2012
  6. doi request reprint Local peritonectomy highly attracts free floating intraperitoneal colorectal tumour cells in a rat model
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, University of Tubingen, Germany
    Cell Physiol Biochem 23:371-8. 2009
  7. doi request reprint Cytoreductive surgery and HIPEC in peritoneal recurrent ovarian cancer: experience and lessons learned
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Langenbecks Arch Surg 396:1077-81. 2011
  8. doi request reprint (18)F-FDG-PET/CT to select patients with peritoneal carcinomatosis for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
    Christina Pfannenberg
    Department of Radiology and Nuclear Medicine, University of Tuebingen, Tubingen, Germany
    Ann Surg Oncol 16:1295-303. 2009
  9. doi request reprint Hepatic glucokinase expression is associated with lipogenesis and fatty liver in humans
    Andreas Peter
    Department of Internal Medicine, Division of Endocrinology, University of Tubingen, 72076 Tubingen, Germany
    J Clin Endocrinol Metab 96:E1126-30. 2011
  10. doi request reprint Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis in a liver graft recipient: a case report
    Philipp Horvath
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, University of Tubingen, Tubingen, Germany
    Ann Transplant 18:182-6. 2013

Collaborators

Detail Information

Publications32

  1. doi request reprint Do patient- and tumor-related factors predict the peritoneal spread of pancreatic adenocarcinoma?
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, University of Tübingen Comprehensive Cancer Center, Hoppe Seyler Strasse 3, 72076, Tubingen, Germany
    Surg Today 44:260-3. 2014
    ..However, peritoneal spread cannot be reliably detected radiographically during preoperative tumor staging...
  2. doi request reprint Risk factors for recurrence following complete cytoreductive surgery and HIPEC in colorectal cancer-derived peritoneal surface malignancies
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, University of Tubingen, Hoppe Seyler Strasse 3, 72076, Tubingen, Germany
    Langenbecks Arch Surg 398:745-9. 2013
    ..Recurrent disease following complete cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a relevant clinical scenario. We aimed to determine risk factors for recurrence...
  3. pmc Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: where are we?
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Tubingen University Hospital, D 72076 Tubingen, Germany Germany
    World J Gastroenterol 18:5317-20. 2012
    ....
  4. pmc Selection criteria for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in gastric cancer
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Tubingen University Hospital, 72076 Tubingen, Germany
    World J Gastroenterol 17:4153-6. 2011
    ..This article sets forth criteria for selection of gastric cancer patients suffering from peritoneal carcinomatosis...
  5. pmc Experience after 100 patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
    Ingmar Königsrainer
    Department of Surgery, University of Tubingen, Hoppe Seyler Strasse 3, D 72076 Tubingen, Germany
    World J Gastroenterol 18:2061-6. 2012
    ..To investigate perioperative patient morbidity/mortality and outcome after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)...
  6. doi request reprint Local peritonectomy highly attracts free floating intraperitoneal colorectal tumour cells in a rat model
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, University of Tubingen, Germany
    Cell Physiol Biochem 23:371-8. 2009
    ..Tumour recurrence may occur early after surgery. One potential mechanism is the ability of peritoneal lesions to attract tumour cells...
  7. doi request reprint Cytoreductive surgery and HIPEC in peritoneal recurrent ovarian cancer: experience and lessons learned
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, University of Tubingen, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Langenbecks Arch Surg 396:1077-81. 2011
    ..De novo cytoreductive surgery is crucial with the potential to improve prognosis, especially when combined with hyperthermic intraperitoneal chemotherapy (HIPEC)...
  8. doi request reprint (18)F-FDG-PET/CT to select patients with peritoneal carcinomatosis for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
    Christina Pfannenberg
    Department of Radiology and Nuclear Medicine, University of Tuebingen, Tubingen, Germany
    Ann Surg Oncol 16:1295-303. 2009
    ..This study was designed to predict tumor load in patients with PC using dual-modality (18)FDG-PET/CT and to compare the results with those of PET and CT alone by correlating imaging findings with intraoperative staging...
  9. doi request reprint Hepatic glucokinase expression is associated with lipogenesis and fatty liver in humans
    Andreas Peter
    Department of Internal Medicine, Division of Endocrinology, University of Tubingen, 72076 Tubingen, Germany
    J Clin Endocrinol Metab 96:E1126-30. 2011
    ..Additionally, we investigated whether genetic variation in the liver specific GCK promoter determines liver fat content in humans...
  10. doi request reprint Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis in a liver graft recipient: a case report
    Philipp Horvath
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, University of Tubingen, Tubingen, Germany
    Ann Transplant 18:182-6. 2013
    ..So far experience concerning the use of this treatment option in transplant recipients is lacking...
  11. doi request reprint Induction of tumor stem cell differentiation--novel strategy to overcome therapy resistance in gastric cancer
    Derek Zieker
    Department of General and Transplant Surgery and Comprehensive Cancer Center, University of Tuebingen, Hoppe Seyler Strasse 3, 72076 Tuebingen, Germany
    Langenbecks Arch Surg 398:603-8. 2013
    ..In this study, we investigated if PGK1 is a promising candidate in inducing stem cell differentiation in gastric cancer...
  12. doi request reprint Phosphoglycerate kinase 1 promoting tumor progression and metastasis in gastric cancer - detected in a tumor mouse model using positron emission tomography/magnetic resonance imaging
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, University of Tuebingen, Tuebingen, Germany
    Cell Physiol Biochem 26:147-54. 2010
    ....
  13. doi request reprint Surgery of colorectal carcinoma in patients aged over 80
    Claudius Falch
    Department of Surgery, Comprehensive Cancer Center, University of Tubingen, Hoppe Seyler Strasse 3, Tubingen, Germany
    Onkologie 32:10-6. 2009
    ..The incidence of colorectal carcinoma increases rapidly in aged patients. We investigated retrospectively the differences in treatment relative to the patients' age...
  14. pmc MSH2 and CXCR4 involvement in malignant VIPoma
    Sven Muller
    Department of General, Visceral and Transplant Surgery, Tubingen, Germany
    World J Surg Oncol 10:264. 2012
    ..1 per million per year. The molecular mechanisms that mediate development of VIPomas are poorly investigated and require definition...
  15. doi request reprint A pancreas-preserving technique for the management of symptomatic pancreatic anastomotic insufficiency refractory to conservative treatment after pancreas head resection
    Ingmar Königsrainer
    Department of General, Visceral, and Transplant Surgery, Tubingen University Hospital, Hoppe Seyler Strasse 3, 72076, Tubingen, Germany
    Langenbecks Arch Surg 395:693-6. 2010
    ..Management of symptomatic pancreatic anastomotic insufficiency after pancreas head resection remains controversial. Completion pancreatectomy as one frequently performed option is associated with poor prognosis...
  16. doi request reprint Lactate influences the gene expression profile of human mesenchymal stem cells (hMSC) in a dose dependant manner
    Carl Christoph Schneider
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, Tuebingen, Germany
    Cell Physiol Biochem 30:1547-56. 2012
    ..Lately it has been shown that lactate, in vivo, plays an important role in homing of stem cells. With this work we aimed to show the influence of lactate on the gene expressionprofile of human mesenchymal stem cells (hMSC). Materials and..
  17. doi request reprint Relationships between hepatic stearoyl-CoA desaturase-1 activity and mRNA expression with liver fat content in humans
    Andreas Peter
    Dept of Internal Medicine, University of Tubingen, German Center for Diabetes Research, Germany
    Am J Physiol Endocrinol Metab 300:E321-6. 2011
    ..We suggest that the FA composition of lipid subclasses, rather than of mixed lipids, should be analyzed to estimate SCD1 activity...
  18. ncbi request reprint Cytostatic activity of a 5-fluoro-2'-deoxyuridine-alendronate conjugate against gastric adenocarcinoma and non-malignant intestinal and fibroblast cell lines
    Jürgen Weinreich
    Department of General, Visceral and Transplant Surgery, University of Tubingen, Waldhornlestr 22, 72072 Tubingen, Germany
    Anticancer Res 32:4299-305. 2012
    ....
  19. doi request reprint Morbid obesity and subsequent pancreatic cancer: pylorus-preserving pancreatoduodenectomy after laparoscopic sleeve gastrectomy
    Markus A Küper
    Department of General, Visceral, and Transplantation Surgery, Comprehensive Cancer Center, University of Tubingen, Hoppe Seyler Strasse 3, 72076, Tubingen, Germany
    Obes Surg 19:385-8. 2009
    ..In addition, there is a need for epidemiological studies of patients who undergo bariatric surgery and subsequently develop cancer...
  20. doi request reprint Cytostatic activity of the duplex drug linking 2'-deoxy-5-fluorouridine (5FdU) with 3'-C-ethynylcytidine (ECyd) against gastric adenocarcinoma cell lines
    Jürgen Weinreich
    Department of General, Visceral and Transplant Surgery, University of Tubingen, Tubingen, Germany
    Invest New Drugs 29:1294-302. 2011
    ..Due to its high cytostatic potential the duplex drug, which covalently links two active anticancer compounds, could be a new therapeutic alternative for chemotherapy in gastric cancer, currently treated with different combinations...
  21. doi request reprint Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancer
    Sufian S Ahmad
    Department of General, Visceral and Transplantation Surgery, University of Tubingen, D 72076 Tubingen, Germany
    Int J Oncol 43:586-90. 2013
    ..Furthermore, we propose several genes induced by PGK1 that could account for cell migration, mainly EGR1 and CYR61 together with the transcription factors FOS and JUN...
  22. pmc Phosphoglycerate kinase 1 a promoting enzyme for peritoneal dissemination in gastric cancer
    Derek Zieker
    Department of General Visceral, Transplant Surgery Comprehensive Cancer Center, University of Tuebingen, D 72076 Tuebingen, Germany
    Int J Cancer 126:1513-20. 2010
    ..Thus, PGK1 may serve as prognostic marker and/or be a potential therapeutic target to prevent dissemination of gastric carcinoma cells into the peritoneum...
  23. doi request reprint Hepatic lipid composition and stearoyl-coenzyme A desaturase 1 mRNA expression can be estimated from plasma VLDL fatty acid ratios
    Andreas Peter
    Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, University of Tubingen, Tubingen Germany
    Clin Chem 55:2113-20. 2009
    ..Additionally, we further evaluated commonly used fatty acid ratios [elongase, de novo lipogenesis, and Delta5 and Delta6 desaturase] in plasma VLDL and hepatic lipid fractions...
  24. ncbi request reprint Predictive value of routine transcutaneous tissue oxygen tension (tcpO2) measurement for the risk of non-healing and amputation in diabetic foot ulcer patients with non-palpable pedal pulses
    Ruth Ladurner
    Department of General and Transplant Surgery, University Hospital of Tubingen, Germany
    Med Sci Monit 16:CR273-7. 2010
    ..It was evaluated whether transcutaneous tissue oxygen tension (tcpO2) measurement, when assessed in daily routine, can be used to predict the risk of non-healing and amputation in diabetic foot ulcer patients with non-palpable pedal pulses...
  25. doi request reprint PGK1 a potential marker for peritoneal dissemination in gastric cancer
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, Tuebingen, Germany
    Cell Physiol Biochem 21:429-36. 2008
    ..The mechanisms that mediate peritoneal carcinomatosis in diffuse primary gastric tumours require definition...
  26. pmc Simultaneous adrenal and extra-adrenal myelolipoma - an uncommon incident: case report and review of the literature
    Derek Zieker
    Department of General, Visceral and Transplant Surgery, Comprehensive Cancer Center, Tuebingen, Germany
    World J Surg Oncol 6:72. 2008
    ..Other soft tissue tumours such as well-differentiated liposarcomas appear morphological almost identical. Preoperative imaging and especially biopsy are important tools to diagnose these lesions...
  27. doi request reprint ALPPS in right trisectionectomy: a safe procedure to avoid postoperative liver failure?
    Jun Li
    General, Visceral and Transplantation Surgery, University Hospital Tuebingen, Tuebingen, Germany
    J Gastrointest Surg 17:956-61. 2013
    ..The aim of this study was to further assess the perioperative risk of this procedure and its specific indications...
  28. doi request reprint Preserving duodenal passage for bone mineralization: Billroth I versus Billroth II reconstruction after partial gastrectomy in growing minipigs
    Ingmar Königsrainer
    Department of General, Visceral, and Transplant Surgery, University Hospital Tubingen, Tubingen, Germany
    J Surg Res 155:321-9. 2009
    ..Therefore, we investigated the impact of duodenal exclusion on bone mineralization in respect to newer duodenal preserving operations in morbid obesity surgery...
  29. doi request reprint The gut is not only the target but a source of inflammatory mediators inhibiting gastrointestinal motility during sepsis
    Ingmar Königsrainer
    University of Tubingen, Department of General, Visceral and Transplant Surgery, Hoppe Seyler Strasse 3, Tubingen, Germany
    Cell Physiol Biochem 28:753-60. 2011
    ..Aim: The aim of the study was to investigate whether the gastrointestinal tract is not only the target but also the source of inflammatory mediators inhibiting gastrointestinal motility...
  30. pmc Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene
    Konstantinos Kantartzis
    Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Medicine, Nephrology and Clinical Chemistry, University of Tubingen, Tubingen, Germany
    Diabetes 58:2616-23. 2009
    ..We investigated whether the SNP determines liver fat independently of visceral adiposity and whether it may even play a role in protecting from insulin resistance...
  31. doi request reprint Sudden death after pancreatic head resection: rupture of hepatic artery caused by clostridial infection
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Tubingen University Hospital, Tubingen, Germany
    Surg Infect (Larchmt) 8:615-9. 2007
    ..Rupture of the hepatic artery caused by clostridial infection has not been reported before...
  32. ncbi request reprint Liver resection without hilus preparation and with selective intrahepatic hilus stapling for benign tumors and liver metastasis
    Ingmar Königsrainer
    Department of General, Visceral and Transplant Surgery, Tubingen University Hospital, Hoppe Seyler Strasse 3, 72076 Tubingen, Germany
    Langenbecks Arch Surg 392:485-8. 2007
    ..Our primary aim was to analyze the feasibility, blood loss, blood transfusion requirements, incidence of complications, and outcome using the approach for intrahepatic devascularization leaving the extrahepatic hilus untouched...