Research Topics
Species | T KlotzSummaryCountry: Germany Publications
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Detail Information
Publications
Effectiveness of oral L-arginine in first-line treatment of erectile dysfunction in a controlled crossover studyT Klotz
Department of Urology, University of Cologne, Germany
Urol Int 63:220-3. 1999..Some studies report good clinical results under oral L-arginine medication in the treatment of erectile dysfunction. We examined the effectiveness and safety of L-arginine in the treatment of mixed-type impotence...
Erectile dysfunction in cyclists. Is there any difference in penile blood flow during cycling in an upright versus a reclining position?F Sommer
Department of Urology, University Medical Centre of Cologne, Germany
Eur Urol 39:720-3. 2001..Perineal compression during bicycling appears to be responsible for some cases of erectile dysfunction...
Localization of constitutive nitric oxide synthase isoforms and the nitric oxide target enzyme soluble guanylyl cyclase in the human bladderB Fathian-Sabet
Department of Urology and Institut I of Anatomy, University of Cologne, Cologne, Germany
J Urol 165:1724-9. 2001..Furthermore, the urothelium may also be a target of nitric oxide...
The prevalence of Peyronie's disease: results of a large surveyU Schwarzer
Department of Urology, University of Cologne, Germany
BJU Int 88:727-30. 2001..2%; this is much higher than indicated in previous reports. A comparably high prevalence is reported for diabetes and urolithiasis, suggesting that this 'rare' disease is more widespread than previously thought...
MAP kinase 1/2 (Erk 1/2) and serine/threonine specific protein kinase Akt/PKB expression and activity in the human corpus cavernosumF Sommer
Department of Urology, University Medical Centre of Cologne, Cologne, Germany
Int J Impot Res 14:217-25. 2002..Furthermore, we found a higher basal level of active MAP Kinase 1/2 (Erk 1/2) in impotent patients. This finding gives the first evidence for an inhibitory influence of MAP Kinase 1/2 (Erk 1/2) on cavernosal eNOS activity...
Vardenafil increases penile rigidity and tumescence in erectile dysfunction patients: a RigiScan and pharmacokinetic studyT Klotz
Department of Urology, University of Cologne, Germany
World J Urol 19:32-9. 2001..The observed pro-erectile properties, pharmacokinetic characteristics and safety profile make vardenafil a suitable candidate for further evaluation in the treatment of erectile dysfunction...
Comparison of individual urologists' performanceF Sommer
Department of Urology, University Medical Centre of Cologne, and Paracelsus Klinik Golzheim, Dusseldorf, Germany
Eur Urol 39:369-74. 2001..The purpose of our study was to compare the crude operative morbidity and mortality rates with the predicted rates using an established scoring system (POSSUM)...
Sildenafil (Viagra): is there an influence on psychological performance?H Grass
Institute of Forensic Medicine, University of Cologne, Germany
Int Urol Nephrol 32:409-12. 2001..We wanted to verify the hypothesis whether sildenfail influences human psychomotor performance, especially under the aspect of traffic safety, or not...
Impotence and genital numbness in cyclistsF Sommer
Department of Urology, University Medical Center of Cologne, Germany
Int J Sports Med 22:410-3. 2001..Therefore, we suggest restricting the training distance, and taking sufficient pauses during the course of prolonged and vigorous bicycle riding, in order to avoid penile numbness and impotence...
Epidemiology of Peyronie's diseaseF Sommer
Department of Urology, University Medical Center of Cologne, Cologne, Germany
Int J Impot Res 14:379-83. 2002..Comparably high prevalences are known for diabetes and urolithiasis, suggesting a greater frequency of this rare disease than formerly believed...
Modulation of human platelet aggregation by the phosphodiesterase type 5 inhibitor sildenafilR Berkels
Department of Pharmacology, University of Cologne, Germany
J Cardiovasc Pharmacol 37:413-21. 2001..After co-administration of nitric oxide, collagen- and ADP-induced platelet aggregation was significantly inhibited, which may reflect physiologic conditions of an in vivo system...
Risk adjustment for evaluating the outcome of urological operative proceduresF Sommer
Department of Urology, University Medical Center of Cologne, Cologne, Germany
J Urol 166:968-72. 2001..Our study shows that the scoring system applied is suitable for urological audit and may be a valuable tool for comparing performance at various units...
Measurement of vaginal and minor labial oxygen tension for the evaluation of female sexual functionF Sommer
Department of Urology, University Medical Center of Cologne, , Germany
J Urol 165:1181-4. 2001..We developed a simple noninvasive reproducible technique to measure vaginal and minor labial blood flow. Age based and cycle dependent normograms now can be produced for vaginal and labial blood flow using this method...
Why do patients with erectile dysfunction abandon effective therapy with sildenafil (Viagra)?T Klotz
Department of Urology, Klinikum Weiden, Weiden, Germany
Int J Impot Res 17:2-4. 2005..The majority reported that they had had no opportunity or desire for sexual intercourse or that their partners had shown no sexual interest. Few patients stated that the high cost of the medication or that adverse events were the cause...
Immunolocalization of inducible and constitutive nitric oxide synthases in human bladder cancerT Klotz
Department of Urology and Institute I of Anatomy, University of Cologne, Germany
Urology 54:416-9. 1999..NO generation by inducible NOS (iNOS) also influences the cytotoxicity of macrophages and tumor-induced immunosuppression. Before now, the expression of iNOS and constitutive NOS in bladder carcinoma tissue had not been determined...
Her-2/neu expression in testicular cancer--a retrospective analysis in 57 casesD Pfister
Department of Urology, RWTH University of Aachen, Weiden, Germany
Urology 76:1266.e6-9. 2010..To evaluate her-2/neu expression in testicular germ cell tumors (GCT)...
Diffuse metastasized testicular teratoma and paraneoplastic thyreotoxicosis. Case report and literature reviewP Derakhshani
Department of Urology, University of Cologne, Germany
Urol Int 63:265-7. 1999..Evaluation of thyroid hormone levels in all patients with serum HCG levels exceeding 20,000 U/l is recommended...
