Research Topics
| A P Klockgether-RadkeSummaryCountry: Germany Publications
| Collaborators |
Detail Information
Publications
[F. W. Sertürner and the discovery of morphine. 200 years of pain therapy with opioids]A P Klockgether-Radke
Zentrum Anaesthesiologie, Rettungs und Intensivmedizin, Georg August Universitat Gottingen
Anasthesiol Intensivmed Notfallmed Schmerzther 37:244-9. 2002..He isolated morphine, the first pure opioid available for calculated pain therapy with one defined compound. Moreover, he laid the foundations of a new class of pharmaceutical drugs, the alcaloids...
[Opioid intoxication following transdermal administration of fentanyl]A P Klockgether-Radke
Zentrum Anaesthesiologie, Rettungs und Intensivmedizin, Georg August Universitat Gottingen, Robert Koch Strasse 40, 37075 Gottingen
Anaesthesist 51:269-71. 2002..The patient was supervised in an ICU for 24 h and sent home the next day without serious sequelae. The consequences following inappropriate use of transdermal fentanyl are discussed...
High-dose midazolam and the attenuation of the contractile response to vasoconstrictors in coronary artery segmentsA P Klockgether-Radke
Georg August University of Gottingen, Department of Anaesthesiological Research, Centre of Anaesthesiology, Emergency and Intensive Care Medicine, Gottingen, Germany
Eur J Anaesthesiol 20:289-93. 2003..Benzodiazepines may cause hypotension and are reported to interfere with smooth vascular muscle activity. The aim was to elucidate the influence of three different benzodiazepines on the vascular reactivity of coronary arteries...
[Ketamine attenuates the contractile response to vasoconstrictors in isolated coronary artery rings]A P Klockgether-Radke
Zentrum Anasthesiologie, Rettungs und Intensivmedizin, Kliniken der Universität Göttingen
Anasthesiol Intensivmed Notfallmed Schmerzther 38:767-71. 2003..Ketamine was shown to increase coronary blood flow. It was the aim of this study to answer the question whether ketamine directly dilates coronary arteries...
Activation of the K+ channel BK(Ca) is involved in the relaxing effect of propofol on coronary arteriesA P Klockgether-Radke
Georg August University of Gottingen, Centre of Anaesthesiology, Emergency and Intensive Care Medicine, Department of Anesthesiological Research, Gottingen, Germany
Eur J Anaesthesiol 21:226-30. 2004..Propofol may cause undesirable hypotension due to vasodilation. The underlying mechanisms are not completely understood. We investigated the mechanisms by which propofol relaxes vascular segments...
[Malposition of a central venous catheter in a patient with severe chest trauma]A P Klockgether-Radke
Zentrum Anasthesiologie, Rettungs und Intensivmedizin, Georg August Universitat Gottingen
Anasthesiol Intensivmed Notfallmed Schmerzther 39:292-6. 2004..Correct position of the catheter must be verified using appropriate methods including chest X-ray, intracardiac ECG tracing or display of the central venous pressure curve on a monitor...
[Tracheotomy for the long-term ventilator-dependent patient?]A P Klockgether-Radke
Zentrum Anasthesiologie, Rettungs und Intensivmedizin, Georg August Universitat Gottingen
Anasthesiol Intensivmed Notfallmed Schmerzther 39:335-43. 2004..Tracheotomy is commonly performed in long-term ventilated patients. The aim of this review is to discuss the advantages and disadvantages of tracheotomy...
Mechanisms involved in the relaxing effect of midazolam on coronary arteriesA P Klockgether-Radke
Georg August University of Gottingen, Centre of Anaesthesiology, Emergency and Intensive Care Medicine, Department of Anaesthesiological Research, Gottingen, Germany
Eur J Anaesthesiol 22:135-9. 2005..The mechanisms are not completely understood. This study was designed to investigate the mechanisms involved in the relaxing effect of midazolam on coronary arteries...
Ketamine enantiomers differentially relax isolated coronary artery ringsA P Klockgether-Radke
Georg August University of Goettingen, Centre of Anaesthesiology, Emergency and Intensive Care Medicine, Department of Anaesthesiological Research, Goettingen, Germany
Eur J Anaesthesiol 22:215-21. 2005..This study was designed to determine whether ketamine might stereoselectively relax isolated porcine coronary arteries...
