Research Topics
Genomes and GenesSpecies | Claudia Traidl-HoffmannSummaryAffiliation: Klinikum rechts der Isar Country: Germany Publications
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Detail Information
Publications
Determinants of allergenicityClaudia Traidl-Hoffmann
ZAUM Center for Allergy and Environment, Division of Environmental Dermatology and Allergy, Department of Dermatology and Allergy, Technische Universität Munich, Munich, Germany
J Allergy Clin Immunol 123:558-66. 2009....- [Mucocutaneous candidiasis]C Traidl-Hoffmann
Klinik und Poliklinik fur Dermatologie und Allergologie, Technische Universitat Munchen
Dtsch Med Wochenschr 135:1379-88; quiz 1389-92. 2010.... 
Therapeutic management of atopic eczemaClaudia Traidl-Hoffmann
Department of Dermatology and Allergy, Biederstein, Technische Universitat Munchen, Munchen, Germany
Curr Drug Metab 11:234-41. 2010..Hopefully, the tremendous progress in basic research in the last years will provide new targets for prevention and treatment in the future...- Pollen-derived E1-phytoprostanes signal via PPAR-gamma and NF-kappaB-dependent mechanismsStefanie Gilles
Division of Environmental Dermatology and Allergy Helmholz Center Munich, Zentrum Allergie und Umwelt, Technische Universität Munich, Munich, Germany
J Immunol 182:6653-8. 2009..We conclude that pollen-derived PPE(1) modulate DC function via PPAR-gamma dependent pathways that lead to inhibition of NFkappaB activation and result in reduced DC IL-12 production and consecutive T(H)2 polarization... - Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patientsKilian Eyerich
Division of Environmental Dermatology and Allergy GSF, ZAUM Center for Allergy and Environment, Technical University, Munich, Germany
Int Arch Allergy Immunol 145:213-23. 2008..Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood... - Comparative in situ topoproteome analysis reveals differences in patch test-induced eczema: cytotoxicity-dominated nickel versus pleiotrope pollen reactionKilian Eyerich
ZAUM Center for Allergy and Environment, Division of Environmental Dermatology and Allergy, Helmholtz Zentrum TUM, Munich, Germany
Exp Dermatol 19:511-7. 2010..In summary, our results demonstrate that the NPT reaction is clearly dominated by cytotoxic events, while the APT reaction to pollen grains is more heterogeneous and elicits a combined humoral and cellular immune reaction... - Immunomodulatory mediators from pollen enhance the migratory capacity of dendritic cells and license them for Th2 attractionValentina Mariani
ZAUM Center for Allergy and Environment, Division of Environmental Dermatology and Allergy, GSF National Research Center for Environment and Health Technische Universität München, Biedersteinerstrasse 29, Munich, Germany
J Immunol 178:7623-31. 2007..In summary, our results demonstrate that pollen itself releases regulatory mediators which generate a Th2-promoting micromilieu with preferential recruitment of Th2 cells to the site of pollen exposure... - Altered, but not diminished specific T cell response in chronic mucocutaneous candidiasis patientsKilian Eyerich
Division of Environmental Dermatology and Allergy GSF TUM, ZAUM, Center for Allergy and Environment, Biedersteinerstr 29, Munich, Germany
Arch Dermatol Res 299:475-81. 2007..However, the impaired Th1 cytokine production with an enhanced IL-10 production could play an important role in the pathogenesis of chronic mucocutaneous Candida infections... - Modulation of atopy patch test and skin prick test by pretreatment with 1% pimecrolimus creamStephanie Weissenbacher
Department of Dermatology and Allergy Biederstein, Technical University, Munich, Germany
Int Arch Allergy Immunol 140:239-44. 2006..In a subgroup of patients with atopic eczema (AE), aeroallergens are relevant eliciting factors. The atopy patch test (APT) was proposed as inflammation model for AE... - Impact of pollen on human health: more than allergen carriers?Claudia Traidl-Hoffmann
Division of Environmental Dermatology and Allergy GSF National Research Center for Environment and Health Neuherberg Technical University of Munich, Munich, Germany
Int Arch Allergy Immunol 131:1-13. 2003..This review is an attempt to favour this holistic view of pollen and their impact on human health... - Toxicity of parked motor vehicle indoor airJeroen T M Buters
Division of Environmental Dermatology and Allergy GSFITUM, ZAUM Center for Allergy and Environment, Technical University Munich, Munich, Germany
Environ Sci Technol 41:2622-9. 2007..Our investigations indicated no apparent health hazard of parked motor vehicle indoor air... - IL-22 and TNF-α represent a key cytokine combination for epidermal integrity during infection with Candida albicansStefanie Eyerich
ZAUM Center for Allergy and Environment, Technische Universität and Helmholtz Center Munich, Munich, Germany
Eur J Immunol 41:1894-901. 2011..In summary, we demonstrate that IL-22 and TNF-α represent a potent, synergistic cytokine combination for cutaneous immunity... - Pollen metabolome analysis reveals adenosine as a major regulator of dendritic cell-primed T(H) cell responsesStefanie Gilles
ZAUM Center for Allergy and Environment, Technische Universität München Helmholtz Center, Munich, Germany
J Allergy Clin Immunol 127:454-461.e1-9. 2011..Because these effects could not solely be attributed to the previously identified pollen-associated lipid mediators, the pollen metabolome was analyzed for candidate immunomodulatory substances... - Chronic mucocutaneous candidiasis, from bench to bedsideKilian Eyerich
ZAUM Center for Allergy and Environment, Division of Environmental Dermatology and Allergy TUM Helmholtzzentrum Biedersteinerstr 29, 80802 Munich, Germany
Eur J Dermatol 20:260-5. 2010..Since resistance to anti-mycotic drugs evolves rapidly, efficient and flexible therapeutic management is essential for CMC patients... - Differential in situ expression of IL-17 in skin diseasesMattias Fischer-Stabauer
Department of Dermatology and Allergy, Technische Universität and Helmholtz Center Munich, Biedersteiner Straße 29, Munich, Germany
Eur J Dermatol 22:781-4. 2012..These patterns are relevant for the clinician, since therapeutic approaches targeting differentiation of Th17 cells as well as direct targeting of IL-17 are or will become available... - The pollen enigma: modulation of the allergic immune response by non-allergenic, pollen-derived compoundsStefanie Gilles
Technische Universität and Helmholtz Zentrum München, Biedersteinerstr 29, Munchen, Germany
Curr Pharm Des 18:2314-9. 2012..System biology such as proteome and metabolome analysis will be a useful future approach to better understand pollen biology... - Patients with chronic mucocutaneous candidiasis exhibit reduced production of Th17-associated cytokines IL-17 and IL-22Kilian Eyerich
Division of Environmental Dermatology and Allergy Helmholtz Zentrum TUM, ZAUM Center for Allergy and Environment, Munich, Germany
J Invest Dermatol 128:2640-5. 2008..The inability to clear C. albicans in CMC patients could be due to a defect in the immune response of IL-17-producing T cells... - Year-to-year variation in release of Bet v 1 allergen from birch pollen: evidence for geographical differences between West and South GermanyJeroen T M Buters
Division of Environmental Dermatology and Allergy GSF TUM, ZAUM Center for Allergy and Environment, Technical University Munich, Munich, Germany
Int Arch Allergy Immunol 145:122-30. 2008..The release of the aeroallergen Bet v 1 from pollen is a major determinant in the etiology of allergic airway disease due to birch pollen... - Human epithelial cells of the respiratory tract and the skin differentially internalize grass pollen allergensCornelia Blume
Division of Environmental Dermatology and Allergy, ZAUM Center for Allergy and Environment, HelmholtzZentrum münchen, Technische Universität Munich, Munich, Germany
J Invest Dermatol 129:1935-44. 2009.... - Lipomatous metaplasia after severe and chronic cutaneous inflammationKilian Eyerich
Department of Dermatology and Allergy, Technical University, Munich, Germany
Dermatology 217:52-5. 2008..We diagnosed a lipomatous metaplasia of the dermis and hypothesize that this metaplasia occurred as a consequence of the severe and chronic inflammation of the skin... - Immunomodulatory effects of aqueous birch pollen extracts and phytoprostanes on primary immune responses in vivoJan Gutermuth
Division of Environmental Dermatology and Allergy GSF TUM, GSF National Research Center for Environment and Health, ZAUM Center for Allergy and Environment, Technische Universitat Munchen, Munich, Germany
J Allergy Clin Immunol 120:293-9. 2007....