Alexander F Kurz

Summary

Affiliation: Klinikum rechts der Isar
Country: Germany

Publications

  1. ncbi request reprint A novel treatment for patients with Alzheimer's disease and with vascular dementia
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, D 81675 Munich, Germany
    Ann N Y Acad Sci 977:476-81. 2002
  2. doi request reprint The clinical significance of cognition-focused interventions for cognitively impaired older adults: a systematic review of randomized controlled trials
    Alexander F Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Int Psychogeriatr 23:1364-75. 2011
  3. doi request reprint [Psychosocial interventions in dementia]
    A Kurz
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munchen, Deutschland
    Nervenarzt 84:93-103; quiz 104-5. 2013
  4. ncbi request reprint CORDIAL: cognitive rehabilitation and cognitive-behavioral treatment for early dementia in Alzheimer disease: a multicenter, randomized, controlled trial
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Alzheimer Dis Assoc Disord 26:246-53. 2012
  5. ncbi request reprint [Treatment of behavioral disorders in dementia with risperidone in psychogeriatric out-patients]
    A Kurz
    Technische Universitat Munchen, Psychiatrische Klinik
    MMW Fortschr Med 145:89-95. 2003
  6. doi request reprint Amyloid clearance as a treatment target against Alzheimer's disease
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Alzheimers Dis 24:61-73. 2011
  7. doi request reprint [Carer burden in dementia: origins and intervention]
    A Kurz
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Klinikum rechts der Isar der Technischen Universitat Munchen, Munchen, Deutschland
    Nervenarzt 82:336-42. 2011
  8. doi request reprint Novel insights for the treatment of Alzheimer's disease
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 35:373-9. 2011
  9. doi request reprint Evaluation of a brief educational program for dementia carers: the AENEAS study
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Int J Geriatr Psychiatry 25:861-9. 2010
  10. doi request reprint The concept of dementia: retain, reframe, rename or replace?
    Alexander F Kurz
    Department of Psychiatry and Psychotherapy, Technical University Munich, Germany
    Int Psychogeriatr 22:37-42. 2010

Detail Information

Publications60

  1. ncbi request reprint A novel treatment for patients with Alzheimer's disease and with vascular dementia
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, D 81675 Munich, Germany
    Ann N Y Acad Sci 977:476-81. 2002
  2. doi request reprint The clinical significance of cognition-focused interventions for cognitively impaired older adults: a systematic review of randomized controlled trials
    Alexander F Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Int Psychogeriatr 23:1364-75. 2011
    ..With regard to the limited efficacy of currently available anti-dementia drugs it is crucial to investigate whether such treatments also provide clinically meaningful benefits to cognitively impaired older individuals...
  3. doi request reprint [Psychosocial interventions in dementia]
    A Kurz
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munchen, Deutschland
    Nervenarzt 84:93-103; quiz 104-5. 2013
    ....
  4. ncbi request reprint CORDIAL: cognitive rehabilitation and cognitive-behavioral treatment for early dementia in Alzheimer disease: a multicenter, randomized, controlled trial
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Alzheimer Dis Assoc Disord 26:246-53. 2012
    ..The findings of this study may be helpful for designing further studies that are needed to determine the potential of CR in older adults with dementia...
  5. ncbi request reprint [Treatment of behavioral disorders in dementia with risperidone in psychogeriatric out-patients]
    A Kurz
    Technische Universitat Munchen, Psychiatrische Klinik
    MMW Fortschr Med 145:89-95. 2003
    ..To assess the efficacy and tolerability of risperidone in general practice two open-label prospective studies were performed...
  6. doi request reprint Amyloid clearance as a treatment target against Alzheimer's disease
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    J Alzheimers Dis 24:61-73. 2011
    ..It may take longer than projected in ongoing trials for such neurobiological effects to translate into measurable changes of clinical progression...
  7. doi request reprint [Carer burden in dementia: origins and intervention]
    A Kurz
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Klinikum rechts der Isar der Technischen Universitat Munchen, Munchen, Deutschland
    Nervenarzt 82:336-42. 2011
    ..From these findings and experiences the outline of a psychologically based behavioral intervention for family carers of dementia patients is derived...
  8. doi request reprint Novel insights for the treatment of Alzheimer's disease
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 35:373-9. 2011
    ..Symptomatic treatments will continue to be needed, and psychosocial approaches will retain an essential role in supporting affected individuals and their families...
  9. doi request reprint Evaluation of a brief educational program for dementia carers: the AENEAS study
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Int J Geriatr Psychiatry 25:861-9. 2010
    ..To evaluate the efficacy of a practical, easily implemented, educational intervention in group format for informal carers of persons with dementia...
  10. doi request reprint The concept of dementia: retain, reframe, rename or replace?
    Alexander F Kurz
    Department of Psychiatry and Psychotherapy, Technical University Munich, Germany
    Int Psychogeriatr 22:37-42. 2010
    ..It should be renamed, using a terminology which accommodates scientific advance and meets the requirements of medical communication while preserving the benefits for patients and their families...
  11. doi request reprint Cognitive rehabilitation in patients with mild cognitive impairment
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitaet Muenchen, Munich, Germany
    Int J Geriatr Psychiatry 24:163-8. 2009
    ..To explore the benefits of a multi-component cognitive rehabilitation programme in patients with mild cognitive impairment (MCI)...
  12. doi request reprint Neurobiology of cognitive disorders
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universitat Munchen, Germany
    Curr Opin Psychiatry 22:546-51. 2009
    ..The consequences of these novel insights for therapeutic interventions are also explained...
  13. ncbi request reprint Uncommon neurodegenerative causes of dementia
    Alexander F Kurz
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Moehlstrasse 26, D 81675 Munich, Germany
    Int Psychogeriatr 17:S35-49. 2005
    ..Behavioral change similar to frontotemporal dementia (FTD) is paralleled or followed by the classic features of motor neuron disease...
  14. ncbi request reprint Non-cognitive benefits of galantamine (Reminyl) treatment in vascular dementia
    A Kurz
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Acta Neurol Scand Suppl 178:19-24. 2002
    ....
  15. ncbi request reprint [Mild cognitive disorder. Questions of definition, diagnosis, prognosis and therapy]
    A Kurz
    Klinik fur Psychiatrie und Psychotherapie, Technische Universitat Munchen
    Nervenarzt 75:6-15. 2004
    ..Patients with early-stage Alzheimer's are an important target group for treatment interventions aiming at slowing the neurodegenerative process...
  16. ncbi request reprint [Efficacy of caregiver support groups for dementia]
    A Kurz
    Klinik fur Psychiatrie und Psychotherapie, Technische Universitat Munchen
    Nervenarzt 76:261-9. 2005
    ..S., Australia, and Finland have demonstrated that multimodal counseling programmes led by professionals significantly reduce the number of nursing home admissions and therefore may have considerable importance for health economics...
  17. ncbi request reprint Effects of risperidone on behavioral and psychological symptoms associated with dementia in clinical practice
    Alexander Kurz
    Technical University Munich, Clinic for Psychiatry, Munich, Germany
    Int Psychogeriatr 17:605-16. 2005
    ..Risperidone significantly improves behavioral and psychological symptoms of dementia (BPSD), including aggression, agitation and psychosis, as shown by randomized, placebo-controlled trials...
  18. ncbi request reprint Potential biological markers for cerebrovascular disease
    Alexander Kurz
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Int Psychogeriatr 15:89-97. 2003
    ..Among biochemical markers in the CSF, tau protein, phospho-tau, and beta amyloid protein are helpful to differentiate vascular dementia from Alzheimer's disease...
  19. ncbi request reprint [Treatment of behavioral disorders in dementia with risperidone in psychogeriatric outpatients]
    A Kurz
    TU Munchen, Psychiatrische Klinik Möhlstrasse 26, D 81675 Munchen
    MMW Fortschr Med 145:55. 2003
  20. ncbi request reprint Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease
    Alexander Drzezga
    Department of Nuclear Medicine, Technische Universitat, Munchen, Ismaninger Str 22, D 81675 Munich, Germany
    Neuroimage 39:619-33. 2008
    ....
  21. doi request reprint Brain metabolic correlates of cerebrospinal fluid beta-amyloid 42 and tau in Alzheimer's disease
    Ruth Vukovich
    Department of Psychiatry and Psychotherapy, Neurochemistry and Neurogenetics Laboratory, Technische Universitat Munchen, Munchen, Germany
    Dement Geriatr Cogn Disord 27:474-80. 2009
    ..Their topographic origin and their association with synaptic dysfunction are still not well understood...
  22. ncbi request reprint Non-fluent progressive aphasia: cerebral metabolic patterns and brain reserve
    Robert Perneczky
    Departments of Psychiatry and Psychotherapy, Technische Universitat Munchen, Germany
    Brain Res 1133:178-85. 2007
    ..05). We conclude that brain reserve is also present in NFPA...
  23. ncbi request reprint Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study
    Alexander Drzezga
    Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675, Munchen, Germany
    Eur J Nucl Med Mol Imaging 30:1104-13. 2003
    ..A newly emerging reduction of rCMRglc in prefrontal cortical areas is associated with the transition from MCI to AD...
  24. ncbi request reprint Association of the tau haplotype H2 with age at onset and functional alterations of glucose utilization in frontotemporal dementia
    Simon M Laws
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Munich University of Technology, 81675 Munich, Germany
    Am J Psychiatry 164:1577-84. 2007
    ..The aim of this study was to investigate the MAPT haplotypes in relation to risk for, and functional alterations of glucose metabolism in, patients with frontotemporal dementia (FTD)...
  25. ncbi request reprint Prediction of individual clinical outcome in MCI by means of genetic assessment and (18)F-FDG PET
    Alexander Drzezga
    Department of Nuclear Medicine, Technische Universitat, Munchen, Munich, Germany
    J Nucl Med 46:1625-32. 2005
    ....
  26. doi request reprint Education, occupation, and dementia: the Bavarian school sisters study
    Horst Bickel
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munchen, Germany
    Dement Geriatr Cogn Disord 27:548-56. 2009
    ....
  27. doi request reprint Activities of daily living, cerebral glucose metabolism, and cognitive reserve in Lewy body and Parkinson's disease
    Robert Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Dement Geriatr Cogn Disord 26:475-81. 2008
    ....
  28. doi request reprint Accelerated clinical decline in well-educated patients with frontotemporal lobar degenerations
    Robert Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, 81675 Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 259:362-7. 2009
    ..There was a significant positive association between education and CDR-SOB monthly rate of change, indicating a faster decline in the well-educated. Education was the only significant predictor of clinical deterioration...
  29. pmc Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid
    Timo Grimmer
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich 81675, Germany
    Biol Psychiatry 65:927-34. 2009
    ..The aim of the study was to determine the association between cerebral amyloid plaque load, as measured by means of the positron emission tomography (PET) tracer carbon-11-labeled Pittsburgh Compound B ([11C]PiB) and CSF Abeta42 in AD...
  30. pmc Progression of cerebral amyloid load is associated with the apolipoprotein E ε4 genotype in Alzheimer's disease
    Timo Grimmer
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universitat Munchen, Munich, Federal Republic of Germany
    Biol Psychiatry 68:879-84. 2010
    ..Only few data have been published on in vivo longitudinal changes of amyloid load in Alzheimer's disease (AD) patients, with conflicting results. Therefore, little is known about the factors that influence these changes...
  31. doi request reprint Metabolic alterations associated with impaired clock drawing in Lewy body dementia
    Robert Perneczky
    Department of Psychiatry and Psychotherapy, Technische Ismaninger Str 22, 81675 Munchen, Germany
    Psychiatry Res 181:85-9. 2010
    ..These findings also suggest that the CDT is an appropriate screening instrument for this disorder and that metabolic dysfunction, and therefore disease severity, is mirrored by performance on the test...
  32. doi request reprint Fluoro-deoxy-glucose positron emission tomography correlates of impaired activities of daily living in dementia with Lewy bodies: implications for cognitive reserve
    Robert Perneczky
    Departments of Psychiatry and Psychotherapy, Technical University Munich, Ismaninger Strasse 22, Munich, Germany
    Am J Geriatr Psychiatry 17:188-95. 2009
    ....
  33. pmc Education attenuates the effect of medial temporal lobe atrophy on cognitive function in Alzheimer's disease: the MIRAGE study
    Robert Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munchen, Germany
    J Alzheimers Dis 17:855-62. 2009
    ..Most interestingly, the interaction term between education and MTA was significant suggesting that education modifies the relation of MTA to cognition. At any level of pathology, cognition remained higher for better educated individuals...
  34. ncbi request reprint Impact of Alzheimer's disease on the functional connectivity of spontaneous brain activity
    Christian Sorg
    Department of Psychiatry, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
    Curr Alzheimer Res 6:541-53. 2009
    ..Finally, rs-fMRI seems to have the potential to produce connectivity-related biomarkers that distinguish AD and healthy aging...
  35. doi request reprint Cerebral metabolic dysfunction in patients with dementia with Lewy bodies and visual hallucinations
    Robert Perneczky
    Department of Psychiatry and Psychotherapy, Technical University Munich, Munich, Germany
    Dement Geriatr Cogn Disord 25:531-8. 2008
    ..To identify the pattern of cerebral hypometabolism in patients with dementia with Lewy bodies (DLB) and visual hallucinations (VH)...
  36. doi request reprint Clinical severity of Alzheimer's disease is associated with PIB uptake in PET
    Timo Grimmer
    Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universitat Munchen, Ismaninger Str 22, 81675 Munich, Germany
    Neurobiol Aging 30:1902-9. 2009
    ..In a cross-sectional study we examined the association between the severity of dementia assessed using the Clinical Dementia Rating scale sum of boxes (CDR-SOB) and [11C]PIB-PET in patients with Alzheimer's disease (AD)...
  37. doi request reprint Right prefrontal hypometabolism predicts delusions in dementia with Lewy bodies
    Robert Perneczky
    Department of Psychiatry and Psychotherapy, Technical University Munich, Munchen, Germany
    Neurobiol Aging 30:1420-9. 2009
    ..VH and overall cognitive dysfunction were no significant predictors. These results underline the significance of right prefrontal damage for DEL in DLB...
  38. ncbi request reprint [Associations between dementia and head circumference as a measure of brain reserve--results from the Bavarian School sisters study]
    Horst Bickel
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie der Technischen Universitat Munchen, Klinikum rechts der Isar
    Psychiatr Prax 33:138-44. 2006
    ..The aim of the study was to examine the relationship of head circumference as a marker of maximal attained brain size to late-life cognitive impairment and dementia...
  39. ncbi request reprint Complex activities of daily living in mild cognitive impairment: conceptual and diagnostic issues
    Robert Perneczky
    Department of Psychiatry, Technische Universitat Munchen, Germany
    Age Ageing 35:240-5. 2006
    ..The concept of an ADL threshold that separates MCI from dementia, however, appears to be improbable for several reasons...
  40. ncbi request reprint Mapping scores onto stages: mini-mental state examination and clinical dementia rating
    Robert Perneczky
    Department of Psychiatry and Psychotherapy and the Institute of Medical Statistics and Epidemiology, Technische Universitat Munchen, Germany
    Am J Geriatr Psychiatry 14:139-44. 2006
    ..In the present study, the authors mapped Mini-Mental State Examination (MMSE) scores onto CDR categories to determine how well the MMSE performs as a surrogate of the CDR as a timesaving method of staging dementia...
  41. ncbi request reprint Effects of cholinesterase inhibitors on behavioural disturbances in Alzheimer's disease: a systematic review
    Timo Grimmer
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Drugs Aging 23:957-67. 2006
    ....
  42. ncbi request reprint Brain reserve capacity in frontotemporal dementia: a voxel-based 18F-FDG PET study
    Robert Perneczky
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Technische Universitat Munchen, Ismaningerstr 22, 81675 Munchen, Germany
    Eur J Nucl Med Mol Imaging 34:1082-7. 2007
    ..The results suggest that brain reserve capacity (BRC) allows patients with more years of schooling to cope better with AD pathology. The objective of this study was to provide initial evidence for BRC in frontotemporal dementia (FTD)...
  43. ncbi request reprint The Ekman 60 Faces Test as a diagnostic instrument in frontotemporal dementia
    Janine Diehl-Schmid
    Department of Psychiatry and Psychotherapy, Technische Universitaet Muenchen, Moehlstrasse 26, D 81675 Munich, Germany
    Arch Clin Neuropsychol 22:459-64. 2007
    ..The results of the present study were consistent with the findings of prior studies on smaller patient samples...
  44. ncbi request reprint Metabolic correlates of brain reserve in dementia with Lewy bodies: an FDG PET study
    Robert Perneczky
    Department of Psychiatry and Psychotherapy, Technical University Munich, Munich, Germany
    Dement Geriatr Cogn Disord 23:416-22. 2007
    ..Research has been mainly focussed on Alzheimer's disease and no studies exist on patients with dementia with Lewy bodies (DLB). The aim of this study was to provide evidence for brain reserve in DLB...
  45. ncbi request reprint Male gender is associated with greater cerebral hypometabolism in frontotemporal dementia: evidence for sex-related cognitive reserve
    Robert Perneczky
    Department of Psychiatry and Psychotherapy, Technical University Munich, Munich, Germany
    Int J Geriatr Psychiatry 22:1135-40. 2007
    ..This suggests that men can compensate more pathology than women...
  46. ncbi request reprint Cerebral metabolic correlates of the clinical dementia rating scale in mild cognitive impairment
    Robert Perneczky
    Department of Psychiatry, Medicine Technische Universität Munchen, Germany
    J Geriatr Psychiatry Neurol 20:84-8. 2007
    ..001, uncorrected for multiple comparisons), which was independent from demographical variables. The authors conclude that clinical severity of impairments is already correlated with deficits in glucose metabolism in the stage of MCI...
  47. ncbi request reprint Impairment of activities of daily living requiring memory or complex reasoning as part of the MCI syndrome
    Robert Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Int J Geriatr Psychiatry 21:158-62. 2006
    ..However, even mild degrees of cognitive deterioration are known to have negative effects on complex ADL...
  48. ncbi request reprint Urinary incontinence and its functional anatomy in frontotemporal lobar degenerations
    Robert Perneczky
    Department of Psychiatry and Psychotherapy, Technical University Munich Medical School, Munich, Germany
    Eur J Nucl Med Mol Imaging 35:605-10. 2008
    ..The aim of the present study was therefore to explore if functional brain lesions were associated with UIC in patients suffering from frontotemporal lobar degenerations (FTLD)...
  49. pmc Selective changes of resting-state networks in individuals at risk for Alzheimer's disease
    Christian Sorg
    Department of Psychiatry, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaningerstrasse 22, 81675 Munich, Germany
    Proc Natl Acad Sci U S A 104:18760-5. 2007
    ..We interpret our finding as a proof of principle, demonstrating that functional brain disorders can be characterized by functional-disconnectivity profiles of RSNs...
  50. pmc Impaired cross-modal inhibition in Alzheimer disease
    Alexander Drzezga
    Department of Nuclear Medicine, Technische Universitat Munchen, Munich, Germany
    PLoS Med 2:e288. 2005
    ....
  51. doi request reprint A 6-month, open-label study of memantine in patients with frontotemporal dementia
    Janine Diehl-Schmid
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Int J Geriatr Psychiatry 23:754-9. 2008
    ..To evaluate safety and effects on cognition and behavior of memantine 20 mg/day in the treatment of patients with frontotemporal dementia (FTD)...
  52. ncbi request reprint The cathepsin D rs17571 polymorphism: effects on CSF tau concentrations in Alzheimer disease
    Matthias Riemenschneider
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Hum Mutat 27:532-7. 2006
    ..The result may corroborate the implication of the lysosomal system in the pathogenesis of AD and is of particular importance if CSF tau is used as a diagnostic biomarker...
  53. pmc Mental health in the aged: prevalence, covariates and related neuroendocrine, cardiovascular and inflammatory factors of successful aging
    Maria E Lacruz
    Institut für Epidemiologie Helmholtz Zentrum München, Munchen, Germany
    BMC Med Res Methodol 10:36. 2010
    ..Specifically, we aim to identify predictors of successful aging and to elucidate bio-psychosocial mechanisms that maintain mental health and successful adaptation despite adverse experiences of life and aging...
  54. ncbi request reprint Weak independent association signals between IDE polymorphisms, Alzheimer's disease and cognitive measures
    Jakob C Mueller
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technical University Munich TUM, Ismaningerstr 22, 81675 Munchen, Germany
    Neurobiol Aging 28:727-34. 2007
    ..A subgroup analysis indicated more prominent associations with AD in younger, and with MMSE in older patients. There may be two independent effects mediated by IDE variants, risk for AD and modification of disease progression...
  55. ncbi request reprint A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease
    Matthias Riemenschneider
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Ismaningerstrasse 22, 81675 Munich, Germany
    Hum Mol Genet 15:2446-56. 2006
    ..Further functional investigations are warranted to elucidate the specific role of PLAU, respectively, PLAU variants in the metabolism of Abeta proteins...
  56. ncbi request reprint Disease stage in Alzheimer disease and treatment effects of rivastigmine
    Alexander Kurz
    Technische Universitat Munchen, Munich, Germany
    Alzheimer Dis Assoc Disord 18:123-8. 2004
    ..Activities of daily living showed statistically significant benefits with rivastigmine across all severity cohorts...
  57. ncbi request reprint Prominent hypometabolism of the right temporoparietal and frontal cortex in two left-handed patients with primary progressive aphasia
    Alexander Drzezga
    Nuklearmedizinische Klinik u Poliklinik, Klinikum rechts der Isar, Ismaninger Strasse 22, 81675 Munchen, Germany
    J Neurol 249:1263-7. 2002
    ..These findings support the hypothesis that PPA can be considered as a symptom complex rather than a disease entity...
  58. doi request reprint Personality of mental health caregivers
    Nicola T Lautenschlager
    Academic Unit for Psychiatry of Old Age, St Vincent s Health, Department of Psychiatry, University of Melbourne, Melbourne, Australia
    Curr Opin Psychiatry 26:97-101. 2013
    ..This review investigated the recent evidence on the role of personality traits and features for caregiver burden and depression in caregivers of care recipients with mental illness...
  59. doi request reprint Personal perspectives of persons with Alzheimer's disease and their carers: a global survey
    Alexander Kurz
    Munich University of Technology and Science, Munich, Germany
    Alzheimers Dement 4:345-52. 2008
    ..Alzheimer's disease (AD) impacts on persons with AD as well their families. This survey aimed to identify information/communication gaps, and quality of life and other issues, from both perspectives...
  60. ncbi request reprint No association of chromatin-modifying protein 2B with sporadic frontotemporal dementia
    Axel Schumacher
    Laboratory of Neurochemistry and Neurogenetics, Department of Psychiatry and Psychotherapy, Munich, Germany
    Neurobiol Aging 28:1789-90. 2007
    ..Thus, we conclude that CHMP2B can be excluded as a susceptibility gene conferring risk to sporadic forms of FTD...