A Kurz

Summary

Affiliation: Klinikum rechts der Isar
Country: Germany

Publications

  1. pmc Mental health in the aged: prevalence, covariates and related neuroendocrine, cardiovascular and inflammatory factors of successful aging
    Maria E Lacruz
    Institut für Epidemiologie Helmholtz Zentrum München, Munchen, Germany
    BMC Med Res Methodol 10:36. 2010
  2. ncbi request reprint Ginkgo biloba compared with cholinesterase inhibitors in the treatment of dementia: a review based on meta-analyses by the cochrane collaboration
    A Kurz
    Department of Psychiatry and Psychotherapy, Technical University Munich, Munich, Germany
    Dement Geriatr Cogn Disord 18:217-26. 2004
  3. ncbi request reprint Longitudinal changes of cerebral glucose metabolism in semantic dementia
    J Diehl-Schmid
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Dement Geriatr Cogn Disord 22:346-51. 2006
  4. pmc Schooling mediates brain reserve in Alzheimer's disease: findings of fluoro-deoxy-glucose-positron emission tomography
    R Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munchen, Germany
    J Neurol Neurosurg Psychiatry 77:1060-3. 2006
  5. ncbi request reprint Genetic analysis of MAPT haplotype diversity in frontotemporal dementia
    S M Laws
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universität München TU München, Ismaningerstr 22, D 81675 Munchen, Germany
    Neurobiol Aging 29:1276-8. 2008
  6. doi request reprint CSF soluble amyloid precursor proteins in the diagnosis of incipient Alzheimer disease
    R Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Klinikum rechts der Isar, 81675 Munchen, Germany
    Neurology 77:35-8. 2011
  7. ncbi request reprint Cerebral metabolic patterns at early stages of frontotemporal dementia and semantic dementia. A PET study
    J Diehl
    Department of Psychiatry, Technische Universitat Munchen, Munich, Germany
    Neurobiol Aging 25:1051-6. 2004
  8. doi request reprint Head circumference, apolipoprotein E genotype and cognition in the Bavarian School Sisters Study
    R Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, 22, Ismaninger Street, 81675 Munchen, Germany
    Eur Psychiatry 27:219-22. 2012
  9. ncbi request reprint Progression to dementia in clinical subtypes of mild cognitive impairment
    P Alexopoulos
    Department of Psychiatry and Psychotherapy, Technische Universitat, Munchen, Germany
    Dement Geriatr Cogn Disord 22:27-34. 2006
  10. ncbi request reprint Fine mapping of the MAPT locus using quantitative trait analysis identifies possible causal variants in Alzheimer's disease
    S M Laws
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munchen, Germany
    Mol Psychiatry 12:510-7. 2007

Detail Information

Publications72

  1. pmc Mental health in the aged: prevalence, covariates and related neuroendocrine, cardiovascular and inflammatory factors of successful aging
    Maria E Lacruz
    Institut für Epidemiologie Helmholtz Zentrum München, Munchen, Germany
    BMC Med Res Methodol 10:36. 2010
    ..Specifically, we aim to identify predictors of successful aging and to elucidate bio-psychosocial mechanisms that maintain mental health and successful adaptation despite adverse experiences of life and aging...
  2. ncbi request reprint Ginkgo biloba compared with cholinesterase inhibitors in the treatment of dementia: a review based on meta-analyses by the cochrane collaboration
    A Kurz
    Department of Psychiatry and Psychotherapy, Technical University Munich, Munich, Germany
    Dement Geriatr Cogn Disord 18:217-26. 2004
    ..placebo with some doses. An evidence-based medicine approach, taking into account the quality of clinical trials, is essential when assessing the safety and efficacy of medications...
  3. ncbi request reprint Longitudinal changes of cerebral glucose metabolism in semantic dementia
    J Diehl-Schmid
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Dement Geriatr Cogn Disord 22:346-51. 2006
    ..Semantic dementia (SD). Objective: To identify the pattern of decline of cerebral glucose metabolism in SD using cerebral (18)F-fluoro-2-desoxy-D-glucose positron emission tomography scanning ((18)F-FDG-PET)...
  4. pmc Schooling mediates brain reserve in Alzheimer's disease: findings of fluoro-deoxy-glucose-positron emission tomography
    R Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munchen, Germany
    J Neurol Neurosurg Psychiatry 77:1060-3. 2006
    ..Therefore, schooling seems to provide brain reserve against neurodegeneration...
  5. ncbi request reprint Genetic analysis of MAPT haplotype diversity in frontotemporal dementia
    S M Laws
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universität München TU München, Ismaningerstr 22, D 81675 Munchen, Germany
    Neurobiol Aging 29:1276-8. 2008
    ..These findings do not support an association of MAPT with FTD but do not rule out its association with other tauopathies...
  6. doi request reprint CSF soluble amyloid precursor proteins in the diagnosis of incipient Alzheimer disease
    R Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Klinikum rechts der Isar, 81675 Munchen, Germany
    Neurology 77:35-8. 2011
    ..To explore if soluble amyloid precursor proteins (sAPP) in CSF improve the identification of patients with incipient Alzheimer disease (AD) in a group of patients with mild cognitive impairment (MCI)...
  7. ncbi request reprint Cerebral metabolic patterns at early stages of frontotemporal dementia and semantic dementia. A PET study
    J Diehl
    Department of Psychiatry, Technische Universitat Munchen, Munich, Germany
    Neurobiol Aging 25:1051-6. 2004
    ..To determine the patterns of cerebral glucose metabolism in frontotemporal dementia (FTD) and semantic dementia (SD)...
  8. doi request reprint Head circumference, apolipoprotein E genotype and cognition in the Bavarian School Sisters Study
    R Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, 22, Ismaninger Street, 81675 Munchen, Germany
    Eur Psychiatry 27:219-22. 2012
    ..The apolipoprotein E (APOE) ɛ4 allele is correlated with an earlier onset of Alzheimer's disease symptoms; larger head circumference has been associated with an individual resilience against cognitive impairment...
  9. ncbi request reprint Progression to dementia in clinical subtypes of mild cognitive impairment
    P Alexopoulos
    Department of Psychiatry and Psychotherapy, Technische Universitat, Munchen, Germany
    Dement Geriatr Cogn Disord 22:27-34. 2006
    ..To examine the outcome among patients diagnosed with different types of mild cognitive impairment (MCI)...
  10. ncbi request reprint Fine mapping of the MAPT locus using quantitative trait analysis identifies possible causal variants in Alzheimer's disease
    S M Laws
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munchen, Germany
    Mol Psychiatry 12:510-7. 2007
    ..002, uncorrected). These findings provide functional evidence to support the genetic association of MAPT with AD...
  11. ncbi request reprint Association study between the D10S1423 microsatellite marker and Alzheimer's disease
    H Gohlke
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universität München TUM, Ismaningerstr 22, D 81675 Munich, Germany
    Neurobiol Aging 27:776.e1-776.e3. 2006
    ..015, uncorrected; p = 0.11, corrected). These findings do not support the presence of a relevant susceptibility locus for AD on chromosome 10p12-14...
  12. ncbi request reprint No association of vacuolar protein sorting 26 polymorphisms with Alzheimer's disease
    M Riemenschneider
    Laboratory of Neurochemistry and Neurogenetics, Department of Psychiatry and Psychotherapy, TU Munich, 81675 Munich, Germany
    Neurobiol Aging 28:883-4. 2007
    ..Thus, we conclude that VPS26 can be excluded as a major positional and functional candidate gene conferring risk to AD...
  13. ncbi request reprint Prion protein codon 129 polymorphism and risk of Alzheimer disease
    M Riemenschneider
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Ismaningerstr 22, 81675 Munich, Germany
    Neurology 63:364-6. 2004
    ..013, OR = 1.92, 95% CI = 1.31 to 2.87), whereas no association was obtained in patients with onset at older than 70 years. The results suggest involvement of the prion protein in the pathogenesis of early-onset AD...
  14. ncbi request reprint Decline of cerebral glucose metabolism in frontotemporal dementia: a longitudinal 18F-FDG-PET-study
    J Diehl-Schmid
    Department of Psychiatry and Psychotherapy, Technische Universitaet Muenchen, Moehlstrasse 26, D 81675 Munich, Germany
    Neurobiol Aging 28:42-50. 2007
    ..To identify the pattern of progression of decline of cerebral glucose metabolism in frontotemporal dementia (FTD, frontal variant)...
  15. ncbi request reprint Cerebral glucose metabolism in patients with AD and different APOE genotypes
    A Drzezga
    Department of Nuclear Medicine, Technische Universitat Munchen, Munich, Germany
    Neurology 64:102-7. 2005
    ..To examine the influence of the APOE epsilon4 allele on cerebral glucose metabolism in a large series of patients with Alzheimer disease (AD)...
  16. ncbi request reprint Frontotemporal dementia, semantic dementia, and Alzheimer's disease: the contribution of standard neuropsychological tests to differential diagnosis
    J Diehl
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    J Geriatr Psychiatry Neurol 18:39-44. 2005
    ....
  17. ncbi request reprint Cerebrospinal beta-amyloid ((1-42)) in early Alzheimer's disease: association with apolipoprotein E genotype and cognitive decline
    M Riemenschneider
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, lsmaningerstrasse 22, 81675, Munich, Germany
    Neurosci Lett 284:85-8. 2000
    ..We conclude that measurement of Abeta42 in CSF might be helpful for identifying AD at an early stage and also for tracking the clinical course...
  18. doi request reprint No association of Tachykinin receptor 2 (TACR2) polymorphisms with Alzheimer's disease
    P Friedrich
    Laboratory of Neurochemistry and Neurogenetics, Department of Psychiatry and Psychotherapy, TU Munchen, Munich, Germany
    Neurobiol Aging 32:544-5. 2011
    ..Genotyping of 13 single nucleotide polymorphisms (SNPs) covering the entire gene and haplotypic analysis revealed no association with AD. Thus, we conclude that TACR2 can be excluded as a major susceptibility gene conferring risk to AD...
  19. ncbi request reprint Validation of the Addenbrooke's cognitive examination for detecting early Alzheimer's disease and mild vascular dementia in a German population
    P Alexopoulos
    Department of Psychiatry and Psychotherapy, Zentrum fur Nervenheilkunde, Universitat Rostock, Rostock, Germany
    Dement Geriatr Cogn Disord 22:385-91. 2006
    ..The German version of the ACE is a short and practical but accurate test battery for the identification of AD and VaD, assessing a broad range of cognitive functions and providing a wide profile of cognitive functions/dysfunctions...
  20. doi request reprint No association of lipase C polymorphisms with Alzheimer's disease
    S M Laws
    Laboratory of Neurochemistry and Neurogenetics, Department of Psychiatry and Psychotherapy, TU Munchen, Munich, Germany
    Neurobiol Aging 31:2192-3. 2010
    ..Thus, we conclude that LIPC can be excluded as a major functional candidate gene conferring risk to AD...
  21. ncbi request reprint Behavioral disturbances in the course of frontotemporal dementia
    J Diehl-Schmid
    Department of Psychiatry, Technische Universitat Munchen, Munich, Germany
    Dement Geriatr Cogn Disord 22:352-7. 2006
    ..Objective: The aim of this study was to assess and compare the prevalence and severity of behavioral disturbances in patients with mild FTD and in patients with moderate/severe dementia...
  22. doi request reprint Examination of the current top candidate genes for AD in a genome-wide association study
    T M Feulner
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universität München TUM, Munich, Germany
    Mol Psychiatry 15:756-66. 2010
    ..Finally, our data confirm that GWAS, regardless of the platform, are valuable for the identification of genetic variants associated with AD...
  23. pmc Head circumference, atrophy, and cognition: implications for brain reserve in Alzheimer disease
    R Perneczky
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Neurology 75:137-42. 2010
    ..Clinical and epidemiologic studies suggest that patients with Alzheimer disease (AD) with larger head circumference have better cognitive performance at the same level of brain pathology than subjects with smaller head circumference...
  24. ncbi request reprint Region-specific decline of cerebral glucose metabolism in patients with frontotemporal dementia: a prospective 18F-FDG-PET study
    T Grimmer
    Department of Psychiatry, Technical University Munich, Germany
    Dement Geriatr Cogn Disord 18:32-6. 2004
    ..The aim of this study was to examine the pattern of glucose uptake and the changes over time of metabolic deficits in patients with frontotemporal dementia (FTD)...
  25. ncbi request reprint Lack of association between a single nucleotide polymorphism within the choline acetyltransferase gene and patients with Alzheimer's disease
    S Schwarz
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Ismaningerstrasse 22, 81675 Munich, Germany
    Neurosci Lett 343:167-70. 2003
    ..In addition, the exon 9 SNP (rs868749) was not polymorphic in the studied population. We conclude that the previously identified polymorphism is not associated with AD...
  26. ncbi request reprint Non-cognitive benefits of galantamine (Reminyl) treatment in vascular dementia
    A Kurz
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Acta Neurol Scand Suppl 178:19-24. 2002
    ....
  27. ncbi request reprint Phospho-tau/total tau ratio in cerebrospinal fluid discriminates Creutzfeldt-Jakob disease from other dementias
    M Riemenschneider
    Department of Psychiatry, Technische Universitat Munchen, Munich, Germany
    Mol Psychiatry 8:343-7. 2003
    ..Although the results have to be confirmed in a larger sample, the preliminary data suggest that simultaneous measurement of total tau and P-tau in CSF may be useful to identify patients with CJD...
  28. ncbi request reprint [Mild cognitive impairment]
    R Perneczky
    Klinik und Poliklinik für Psychiatrie und Psychotherapie der Technischen Universität München Alzheimer Zentrum
    MMW Fortschr Med 146:34-7. 2004
    ..In the future, patients with MCI will play an increasingly important role as the target group for the prevention of dementia...
  29. doi request reprint [Mild cognitive impairment with predictors of rapid decline]
    H Forstl
    Klinik and Poliklinik für Psychiatrie and Psychotherapie, TU Munchen, Klinikum rechts der Isar, Ismaningerstr 22, 81675 Munchen
    Dtsch Med Wochenschr 133:431-6. 2008
    ..It is concluded that MCI-plus offers a window for medical and psychological prophylaxis and rehabilitation...
  30. ncbi request reprint [Vascular dementias]
    Janine Diehl
    Klinik fur Psychiatrie und Psychotherapie, Technische Universitat Munchen, Germany
    Fortschr Neurol Psychiatr 70:145-54. 2002
    ....
  31. doi request reprint [Dying demented. Concepts of care and palliative medicine]
    H Forstl
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Technische Universitat Munchen, Germany
    Fortschr Neurol Psychiatr 78:203-12. 2010
    ..We also list a number of areas offering leeway for improvement regarding research, training, psycho-education, preparation, diagnosis, treatment and support...
  32. ncbi request reprint Association analysis of genes involved in cholesterol metabolism located within the linkage region on chromosome 10 and Alzheimer's disease
    M Riemenschneider
    Department of Psychiatry, Neurochemistry and Neurogenetics Laboratory, TU München Ismaningerstr 22, 81675 Munchen, Germany
    Neurobiol Aging 25:1305-8. 2004
    ..None of the polymorphisms showed significant association with AD which contradicts recent findings on CH25H. From our results we conclude that the investigated genetic variations do not contribute to the genetic risk of AD...
  33. ncbi request reprint [Current antidementive therapy]
    R Perneczky
    Klinik und Poliklinik für Psychiatrie und Psychotherapie der TU München
    MMW Fortschr Med 146:53-6. 2004
    ..Ginkgo biloba or piracetam are alternatives for patients with mild-to-moderate dementia, in whom acetylcholinesterase inhibitors cannot be used...
  34. ncbi request reprint A polymorphism of the brain-derived neurotrophic factor (BDNF) is associated with Alzheimer's disease in patients lacking the Apolipoprotein E epsilon4 allele
    M Riemenschneider
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Mol Psychiatry 7:782-5. 2002
    ..The results suggest that the BDNF C-270T polymorphism is a relevant risk factor for AD particularly in patients lacking the ApoE epsilon4 allele in this German sample...
  35. pmc Apolipoprotein E polymorphism in German patients with frontotemporal degeneration
    M Riemenschneider
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Germany
    J Neurol Neurosurg Psychiatry 72:639-41. 2002
    ..Inconclusive results have been reported in patients with frontotemporal degeneration which prompted this study of the apoE polymorphism in a German sample with frontotemporal degeneration...
  36. ncbi request reprint [Frontotemporal dementia]
    Janine Diehl
    Alzheimer Zentrum, Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Technische Universitat Munchen, Möhlstrasse 26, D 81675 Munchen, Deutschland
    Wien Med Wochenschr 152:92-7. 2002
    ..Clinical symptoms and course will be illustrated by a case example. We will also provide guidelines for diagnosis and discuss treatment options...
  37. ncbi request reprint [Features of frontotemporal dementia from the perspective of a special family support group]
    J Diehl
    Klinik fur Psychiatrie und Psychotherapie, Technische Universitat Munchen, Möhlstrasse 26, 81675 Munchen
    Nervenarzt 74:445-9. 2003
    ..Participants' evaluations of the novel intervention were very positive. We conclude from these initial observations that support groups are needed for caregivers of patients with FTD which are tailored to their specific needs...
  38. ncbi request reprint [Frontotemporal dementia. Results from "Frontotemporal Demential and Pick's Disease Conference"]
    J Diehl
    Psychiatrische Klinik und Poliklinik, Technische Universitat Munchen
    Nervenarzt 74:785-7. 2003
    ..Topics included clinical manifestations, differential diagnosis, pathologic and genetic bases of the disease, therapy, and specific problems facing patients and care givers. A consensus in the terminology of this condition was sought...
  39. ncbi request reprint Association of CSF apolipoprotein E, Abeta42 and cognition in Alzheimer's disease
    M Riemenschneider
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry, Technische Universitat Munchen, Germany
    Neurobiol Aging 23:205-11. 2002
    ....
  40. ncbi request reprint Tau and Abeta42 protein in CSF of patients with frontotemporal degeneration
    M Riemenschneider
    Neurochemistry and Neurogenetics Laboratory, Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Ismaningerstrasse 22, 81675 Munich, Germany
    Neurology 58:1622-8. 2002
    ..CSF concentrations of tau and beta-amyloid protein-42 (Abeta42) have been extensively studied in AD. Few data are available concerning CSF levels of both proteins in patients with frontotemporal degeneration (FTD)...
  41. ncbi request reprint Cerebrospinal fluid tau and beta-amyloid 42 proteins identify Alzheimer disease in subjects with mild cognitive impairment
    M Riemenschneider
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Arch Neurol 59:1729-34. 2002
    ..Cerebrospinal fluid tau protein and beta-amyloid 42 (Abeta42) protein are altered even in very mild Alzheimer disease (AD). So far, few data exist for subjects with mild cognitive impairment (MCI)...
  42. pmc Pharmacokinetics of a novel transdermal rivastigmine patch for the treatment of Alzheimer's disease: a review
    A Kurz
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Int J Clin Pract 63:799-805. 2009
    ....
  43. ncbi request reprint Short-term influence of elevation of plasma homocysteine levels on cognitive function in young healthy adults
    P Alexopoulos
    Department of Psychiatry and Psychotherapy, Friedrich Alexander Universitat Erlangen Nurnberg, Erlangen, Germany
    J Nutr Health Aging 14:283-7. 2010
    ..Acute homocysteine elevation has been shown to have a significant impact on cognitive function in animal models...
  44. ncbi request reprint Frontotemporal dementia: patient characteristics, cognition, and behaviour
    J Diehl
    Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany
    Int J Geriatr Psychiatry 17:914-8. 2002
    ....
  45. ncbi request reprint [Forgetfulness and light cognitive impairment. What can the physician still tolerate?]
    H Forstl
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, TU Munchen
    MMW Fortschr Med 143:23-7. 2001
    ..Whether antidementia agents are capable of stopping the progress of mild cognitive impairment to full-blown dementia is currently being investigated in ongoing trials...
  46. ncbi request reprint [Validation of a short test (3MS-R) for detecting Alzheimer's disease]
    P Alexopoulos
    Psychiatrie und Psychotherapie Klinik, Friedrich Alexander Universitat Erlangen Nurnberg, Erlangen
    Fortschr Neurol Psychiatr 75:728-36. 2007
    ..The Modified Mini-Mental State Examination-revised (3MS-R) is a brief cognitive test designed to detect cognitive impairment, which is often used in Canada and USA...
  47. ncbi request reprint A polymorphism in the cystatin C promoter region is not associated with an increased risk of AD
    R C Dodel
    Department of Neurology, Philipps University Marburg, Germany
    Neurology 58:664. 2002
  48. ncbi request reprint Gender differences in brain reserve : an (18)F-FDG PET study in Alzheimer's disease
    R Perneczky
    Dept of Psychiatry and Psychotherapy, Technical University of Munich, Ismaningerstr 22, 81675, Munchen, Germany
    J Neurol 254:1395-400. 2007
    ..Neuropathological studies suggest that the association between neurodegenerative brain damage and clinical symptoms may be stronger in women than in men...
  49. ncbi request reprint Association of an interleukin 1 alpha polymorphism with Alzheimer's disease
    Y Du
    Departments of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, 46202, USA
    Neurology 55:480-3. 2000
    ..The IL-1A(-889) allele 2 polymorphism may be associated with AD pathogenesis...
  50. doi request reprint [Current immune therapy for Alzheimer's disease]
    T Grimmer
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Zentrum für kognitive Störungen, Technische Universitat, Möhlstrasse 26, 81675 Munchen
    Nervenarzt 79:832-5. 2008
    ..Particularly Abeta42 and the clinical research are examined. Ethical and economic questions resulting from successful immunization against Abeta are discussed...
  51. doi request reprint The Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): design and baseline characteristics
    Roy W Jones
    RICE The Research Institute for the Care of Older People, Royal United Hospital, Bath, United Kingdom
    Alzheimers Dement 4:145-53. 2008
    ....
  52. ncbi request reprint [Dementias. Diagnosis and therapy are overwhelmingly the responsibility of the family physician]
    A Kurz
    ,
    MMW Fortschr Med 143:27-32. 2001
    ..Pharmacotherapy must be supplemented by adaptation of the patient's surroundings, and counseling of relatives. However, proper treatment of dementia is cost-intensive and puts a strain on the doctor's medications budget...
  53. doi request reprint Safety and efficacy of galantamine in subjects with mild cognitive impairment
    B Winblad
    Karolinska Institutet, Alzheimer s Disease Research Center, Division of Geriatric Medicine, Stockholm, Sweden
    Neurology 70:2024-35. 2008
    ....
  54. ncbi request reprint [Frontotemporal dementia: specific problems for caregivers]
    Janine Diehl
    Klinik und Poliklinik für Psychiatrie der TU München, Ismaninger Str 22, 81675 Munchen, Germany
    Z Gerontol Geriatr 37:301-6. 2004
    ..The present paper reviews the clinical features of FTD, outlines the specific problems and burdens that caregivers are faced with, and describes novel interventions for this group of family caregivers...
  55. ncbi request reprint [Efficacy of caregiver support groups for dementia]
    A Kurz
    Klinik fur Psychiatrie und Psychotherapie, Technische Universitat Munchen
    Nervenarzt 76:261-9. 2005
    ..S., Australia, and Finland have demonstrated that multimodal counseling programmes led by professionals significantly reduce the number of nursing home admissions and therefore may have considerable importance for health economics...
  56. ncbi request reprint [Treatment of behavioral disorders in dementia with risperidone in psychogeriatric out-patients]
    A Kurz
    Technische Universitat Munchen, Psychiatrische Klinik
    MMW Fortschr Med 145:89-95. 2003
    ..To assess the efficacy and tolerability of risperidone in general practice two open-label prospective studies were performed...
  57. ncbi request reprint [Dementias: communication between doctor, patient and relatives]
    A Kurz
    Klinik fur Psychiatrie und Psychotherapie, Technische Universitat Munchen
    Dtsch Med Wochenschr 129:199-203. 2004
  58. ncbi request reprint [Mild cognitive disorder. Questions of definition, diagnosis, prognosis and therapy]
    A Kurz
    Klinik fur Psychiatrie und Psychotherapie, Technische Universitat Munchen
    Nervenarzt 75:6-15. 2004
    ..Patients with early-stage Alzheimer's are an important target group for treatment interventions aiming at slowing the neurodegenerative process...
  59. ncbi request reprint [Presenile dementia in memory clinics--incidence rates and clinical features]
    H Bickel
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie der Technischen Universitat Munchen, Germany
    Nervenarzt 77:1079-85. 2006
    ..3/100,000. It can be concluded that memory clinics fulfill an important function in the care of patients with presenile dementia, since they are highly utilized by younger patients in early stages of the illness...
  60. ncbi request reprint The Alzheimer variant of lewy body disease: a pathologically confirmed case-control study
    R Perneczky
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie der Technischen Universitat Munchen, Munchen, Deutschland
    Dement Geriatr Cogn Disord 20:89-94. 2005
    ..Taken together, our findings suggest that Lewy body pathology may be present in patients who do not show the typical clinical features which distinguish DLB from AD...
  61. ncbi request reprint [Misdemeanor in frontotemporal dementia]
    J Diehl
    Psychiatrische Klinik und Poliklinik der TU München, Ismaninger Str 22, 81675 Munchen
    Fortschr Neurol Psychiatr 74:203-10. 2006
    ..10 patients with FTD and 3 patients with SD but none of the patients with AD had physically threatened spouses, relatives or strangers. In one case another person was hurt...
  62. ncbi request reprint [German-speaking memory clinics: state of the art and practical recommendations]
    J Diehl
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, TU Munchen, Ismaninger Str 22, 81675 Munich, Germany
    Z Gerontol Geriatr 36:189-96. 2003
    ..The following paper is a summary of the results of a workshop in Göttingen and gives practical recommendations based on the experiences of the memory clinics...
  63. ncbi request reprint Donepezil for Alzheimer's disease in clinical practice--The DONALD Study. A multicenter 24-week clinical trial in Germany
    L Froelich
    Division of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, University of Heidelberg, Heidelberg, Germany
    Dement Geriatr Cogn Disord 18:37-43. 2004
    ..There were only insignificant effects on ECG parameters. This study confirms the results obtained in previous double-blind trials, which showed that donepezil is effective and well tolerated in patients with mild-to-moderately severe AD...
  64. ncbi request reprint Broad therapeutic benefits in patients with probable vascular dementia or Alzheimer's disease with cerebrovascular disease treated with galantamine
    S Lilienfeld
    Janssen Pharmaceutica, Titusville, NJ 08560, USA
    Ann N Y Acad Sci 977:487-92. 2002
  65. ncbi request reprint Clinical features of Alzheimer's disease
    H Forstl
    Department and Clinic of Psychiatry and Psychotherapy, TU Munich
    Eur Arch Psychiatry Clin Neurosci 249:288-90. 1999
    ....
  66. ncbi request reprint A genetic variation of cathepsin D is a major risk factor for Alzheimer's disease
    A Papassotiropoulos
    Department of Psychiatry, University of Bonn, Germany
    Ann Neurol 47:399-403. 2000
    ..0 compared with subjects with neither of these two alleles. Our data confirm the results of a recently performed pilot study in an independent sample and suggest that the catD genotype is strongly associated with the risk for AD...
  67. ncbi request reprint [Validation of a Short Telephone Test (T3MS) for the Diagnosis of Cognitive Impairment]
    P Alexopoulos
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat Rostock, Gehlsheimer Str 20, 18147 Rostock
    Fortschr Neurol Psychiatr 74:329-36. 2006
    ..The interview achieves higher diagnostic precision than the MMSE and contributes to a valid assessment of cognitive performance. For the identification of mild cognitive impairment, however, the T3MS was less appropriate...
  68. ncbi request reprint [Treatment of behavioral disorders in dementia with risperidone in psychogeriatric outpatients]
    A Kurz
    TU Munchen, Psychiatrische Klinik Möhlstrasse 26, D 81675 Munchen
    MMW Fortschr Med 145:55. 2003
  69. ncbi request reprint Selective postoperative inhibition of gastrointestinal opioid receptors
    A Taguchi
    Department of Anesthesiology, Washington University, St Louis, MO 63110, USA
    N Engl J Med 345:935-40. 2001
    ....
  70. ncbi request reprint Effects of continuous remifentanil administration on intra-operative subcutaneous tissue oxygen tension
    B Kabon
    Department of Anaesthesiology and Intensive Care Medicine, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Anaesthesia 62:1101-9. 2007
    ..013. Continuous intra-operative opioid administration may blunt vasoconstriction caused by surgical stress and adrenergic responses more than an equi-effective anaesthetic regimen based on smaller-dose bolus opioid administration...
  71. ncbi request reprint Extrapyramidal signs, primitive reflexes and incontinence in fronto-temporal dementia
    J Diehl-Schmid
    Department of Psychiatry, Technische Universitat Munchen, Munchen, Germany
    Eur J Neurol 14:860-4. 2007
    ..The results have to be confirmed with larger or pooled patient samples from different ascertainment scenarios. If the results of the present study can be replicated, a revision of the consensus criteria from 1998 might be considered...
  72. ncbi request reprint [Initial symptoms, survival and causes of death in 115 patients with frontotemporal lobar degeneration]
    J Diehl-Schmid
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie der Technischen Universitat Munchen
    Fortschr Neurol Psychiatr 75:708-13. 2007
    ..Mortality risk was significantly higher in patients with an early disease onset. Causes of death were varied, but pneumonia and sudden unexplained deaths were particularly frequent...