Research Topics
| H FinkSummaryAffiliation: Klinikum rechts der Isar Country: Germany Publications
| Collaborators |
Detail Information
Publications
Myths and facts in neuromuscular pharmacology. New developments in reversing neuromuscular blockadeH Fink
Klinik fur Anaesthesiologie, Klinikum rechts der Isar der Technischen Universitat Munchen, Germany
Minerva Anestesiol 78:473-82. 2012....
Systemic inflammatory response syndrome increases immobility-induced neuromuscular weaknessHeidrun Fink
Klinik fur Anaesthesiologie, Technischen Universitat Munchen, Klinikum rechts der Isar, Munich, Germany
Crit Care Med 36:910-6. 2008..This study establishes a rat model to examine the effect of inflammation and immobilization alone and in combination on muscle contraction, histology, and acetylcholine receptor regulation...
[Muscle relaxants in Germany 2005: a comparison of application customs in hospitals and private practices]H Fink
Klinik fur Anasthesiologie, Klinikum rechts der Isar, Technische Universitat, Ismaninger Strasse 22, 81675 Munchen
Anaesthesist 55:668-78. 2006..The results of this nationwide survey suggest that time pressure in combination with an increased specialization of anesthetists in private practice are the main factors for availability and use of muscle relaxants in routine anesthesia...
Nitric oxide is not a mediator of inflammation-induced resistance to atracuriumHeidrun Fink
Klinik für Anaesthesiologie der Technischen Universität München, Munich, Germany
Anesth Analg 101:1362-7. 2005....
Muscle relaxant use for tracheal intubation in pediatric anaesthesia: a survey of clinical practice in GermanyD Nauheimer
Klinik fur Anasthesiologie, Intensiv, Notfallmedizin und Schmerztherapie, Klinikum Ludwigsburg, Germany
Paediatr Anaesth 19:225-31. 2009..Aim of this Germany-wide study was to evaluate the use and application customs of neuromuscular blocking drugs (NMBDs) for tracheal intubation in children of age 5 years or younger...
Pharmacokinetics and pharmacodynamics of vecuronium in rats with systemic inflammatory response syndrome: treatment with NG-monomethyl-L-arginineM Blobner
Institut für Anaesthesiogie der Technischen Universität München, Kinikum rechts der Isar, Munich, Germany
Anesthesiology 91:999-1005. 1999..The present study investigated the pharmacodynamics and pharmacokinetics of vecuronium in rats with inflammatory liver dysfunction...
Systemic inflammation leads to resistance to atracurium without increasing membrane expression of acetylcholine receptorsHeidrun Fink
Research Fellow, , Klinikum rechts der Isar, Germany
Anesthesiology 98:82-8. 2003..CONCLUSION: Resistance to atracurium during corynebacterium parvum-induced systemic inflammation is due to increased drug binding to alpha1 -acid glycoprotein and is unrelated to changes in acetylcholine receptor expression...
Inflammatory liver disease shortens atracurium-induced neuromuscular blockade in ratsB Mayer
, Klinikum rechts der Isar, Munich, Germany
Eur J Anaesthesiol 18:599-604. 2001..Further investigations are needed regarding a possible up-regulation of acetylcholine receptors or an increased protein binding of atracurium during sepsis to clarify reasons behind this phenomenon...
Continuous administration of pyridostigmine improves immobilization-induced neuromuscular weaknessChristiane G Frick
Klinik fur Anaesthesiologie, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
Crit Care Med 38:922-7. 2010..Pyridostigmine reversibly blocks acetylcholinesterase and has the potential to improve neuromuscular transmission and decrease acetylcholine receptor number...
[Emergency medication during pregnancy]H Fink
Klinik fur Anaesthesiologie, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Str 22, 81675, Munchen, Deutschland
Med Klin Intensivmed Notfmed 107:123-7. 2012....
The use of sugammadex in a patient with myasthenia gravisC Unterbuchner
Klinik fur Anaesthesiologie, Klinikum rechts der Isar, Technische Universitat Munchen, Munchen, Germany
Anaesthesia 65:302-5. 2010....
Cerebral histopathology following portal venous infusion of bacteria in a chronic porcine modelR Bogdanski
Klinik fur Anaesthesiologie, Institut für Experimentelle Onkologie und Therapieforschung, Technischen Universitat Munchen, Klinikum rechts der Isar, Munich, Germany
Anesthesiology 93:793-804. 2000..The aim of this study was to histologically investigate brain damage after prolonged periods of bacteremia in pigs...
Effects of xenon on mesenteric blood flowR Bogdanski
, , Munich, Germany
Eur J Anaesthesiol 20:98-103. 2003....
Bioavailability of reduced nicotinamide-adenine-dinucleotide (NADH) in the central nervous system of the anaesthetized rat measured by laser-induced fluorescence spectroscopyAndre Rex
Institute of Pharmacology and Toxicology, School of Veterinary Medicine, Freie Universitat Berlin, Koserstr 20, D 14195 Berlin, Germany
Pharmacol Toxicol 90:220-5. 2002..In conclusion, the results suggest that NADH given orally or intraperitoneally increases the amounts of NADH in the brain. The results may thus help to explain the clinical effects reported...
Up-regulation of acetylcholine receptors during subchronic infusion of pancuronium is caused by a posttranscriptional mechanism related to disuseHeidrun Fink
Department of Anasthesia and Critical Care, Massachusetts General Hospital, Boston, MA, USA
Crit Care Med 32:509-13. 2004..This study documents that 12 hrs of disuse per se leads to an increased expression of the acetylcholine receptor number by a posttranscriptional mechanism that can be prevented by nerve-evoked muscle contraction...
