U Darsow

Summary

Affiliation: Klinikum rechts der Isar
Country: Germany

Publications

  1. ncbi request reprint [Atopy patch testing with aeroallergens and food]
    U Darsow
    Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universitat Munchen
    Hautarzt 56:1133-40. 2005
  2. doi request reprint ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis
    U Darsow
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen
    J Eur Acad Dermatol Venereol 24:317-28. 2010
  3. pmc Recent progress in unraveling central nervous system processing of itch sensation
    Florian Pfab
    From the Department of Dermatology and Allergy, Technische Universität München Division of Environmental Dermatology and Allergy, Helmholtz Zentrum Munchen TUM, ZAUM Center for Allergy and Environment and Department of Neurology, Klinikum r d Isar, Technische Universitat Munchen, Munich, Germany
    World Allergy Organ J 1:168-73. 2008
  4. pmc Immunoglobulin e-mediated allergy plays a role in atopic eczema as shown in the atopy patch test
    Ulf Darsow
    From the Department of Dermatology and Allergy Biederstein, Division of Environmental Dermatology and Allergy Helmholtz Center TUM, Technische Universitat Munchen, Munich, Germany
    World Allergy Organ J 1:51-6. 2008
  5. pmc Difficult to control atopic dermatitis
    Ulf Darsow
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen, Munich, Germany
    World Allergy Organ J 6:6. 2013
  6. doi request reprint Allergen-specific immunotherapy for atopic eczema: updated
    Ulf Darsow
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen, ZAUM Center for Allergy and Environment, Munich, Germany
    Curr Opin Allergy Clin Immunol 12:665-9. 2012
  7. doi request reprint Influence of dietary factors, age and nickel contact dermatitis on nickel excretion
    Ulf Darsow
    ZAUM Centre for Allergy and Environment, Munich D 80802, Germany
    Contact Dermatitis 67:351-8. 2012
  8. doi request reprint Itch and eczema
    Ulf Darsow
    Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Munich, Germany
    Chem Immunol Allergy 96:81-8. 2012
  9. doi request reprint Allergen-specific immunotherapy in atopic eczema
    Ulf Darsow
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen, Biedersteiner Strasse 29, 80802, Munchen, Germany
    Curr Allergy Asthma Rep 11:277-83. 2011
  10. doi request reprint Pruritus and atopic dermatitis
    Ulf Darsow
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen, Munich, Germany
    Clin Rev Allergy Immunol 41:237-44. 2011

Detail Information

Publications41

  1. ncbi request reprint [Atopy patch testing with aeroallergens and food]
    U Darsow
    Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universitat Munchen
    Hautarzt 56:1133-40. 2005
    ..The specificity of APT is higher than the specificity of skin prick tests or RAST. More studies for the standardization of APT methods are necessary, especially with regard to food APT...
  2. doi request reprint ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis
    U Darsow
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen
    J Eur Acad Dermatol Venereol 24:317-28. 2010
    ..The diagnosis of atopic dermatitis (AD) is made using evaluated clinical criteria. Management of AD must consider the symptomatic variability of the disease...
  3. pmc Recent progress in unraveling central nervous system processing of itch sensation
    Florian Pfab
    From the Department of Dermatology and Allergy, Technische Universität München Division of Environmental Dermatology and Allergy, Helmholtz Zentrum Munchen TUM, ZAUM Center for Allergy and Environment and Department of Neurology, Klinikum r d Isar, Technische Universitat Munchen, Munich, Germany
    World Allergy Organ J 1:168-73. 2008
    ....
  4. pmc Immunoglobulin e-mediated allergy plays a role in atopic eczema as shown in the atopy patch test
    Ulf Darsow
    From the Department of Dermatology and Allergy Biederstein, Division of Environmental Dermatology and Allergy Helmholtz Center TUM, Technische Universitat Munchen, Munich, Germany
    World Allergy Organ J 1:51-6. 2008
    ..The characterization of a patient subgroup with relevant IgE-mediated allergy may lead to more efficient avoidance and eventually even specific immunotherapy strategies in the management of AE...
  5. pmc Difficult to control atopic dermatitis
    Ulf Darsow
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen, Munich, Germany
    World Allergy Organ J 6:6. 2013
    ..Systemic antihistamines (H1) may relieve pruritus but do not have sufficient effect on eczema. Adjuvant therapy includes UV irradiation preferably of UVA1 wavelength. "Eczema school" educational programs have been proven to be helpful...
  6. doi request reprint Allergen-specific immunotherapy for atopic eczema: updated
    Ulf Darsow
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen, ZAUM Center for Allergy and Environment, Munich, Germany
    Curr Opin Allergy Clin Immunol 12:665-9. 2012
    ..This article summarizes theoretical aspects and recent results of clinical trials associated with ASIT in atopic eczema...
  7. doi request reprint Influence of dietary factors, age and nickel contact dermatitis on nickel excretion
    Ulf Darsow
    ZAUM Centre for Allergy and Environment, Munich D 80802, Germany
    Contact Dermatitis 67:351-8. 2012
    ..Nickel is a frequently detected cause of allergic contact dermatitis. Ingestion of nickel may lead to flares of nickel contact dermatitis...
  8. doi request reprint Itch and eczema
    Ulf Darsow
    Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Munich, Germany
    Chem Immunol Allergy 96:81-8. 2012
    ..In the concept of eczema patient management, the therapy of clinical pruritus has to consider pathophysiology and perception by combining topical and systemic treatment...
  9. doi request reprint Allergen-specific immunotherapy in atopic eczema
    Ulf Darsow
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen, Biedersteiner Strasse 29, 80802, Munchen, Germany
    Curr Allergy Asthma Rep 11:277-83. 2011
    ..This article reviews the theoretical problems and practical results associated with allergen-specific immunotherapy in atopic eczema...
  10. doi request reprint Pruritus and atopic dermatitis
    Ulf Darsow
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen, Munich, Germany
    Clin Rev Allergy Immunol 41:237-44. 2011
    ..In the concept of patient management, the therapy of clinical pruritus has to consider origin and perception of itch, namely the skin and the central nervous system, by combining topical and systemic treatment...
  11. ncbi request reprint Position paper on diagnosis and treatment of atopic dermatitis
    U Darsow
    Department of Dermatology and Allergy Biederstein, Technical University Munich, Germany
    J Eur Acad Dermatol Venereol 19:286-95. 2005
    ..Stress-induced exacerbations may make psychosomatic counselling recommendable. 'Eczema school' educational programmes have proved to be helpful...
  12. ncbi request reprint Processing of histamine-induced itch in the human cerebral cortex: a correlation analysis with dermal reactions
    U Darsow
    Division of Environmental Dermatology and Allergy GSF TUM, Department of Dermatology and Allergy Biederstein, Technical University Munich, Germany
    J Invest Dermatol 115:1029-33. 2000
    ..Other areas may be involved in emotional processing of sensations. Skin reactions wheal and flare also had significantly activated covariate areas in the central nervous system.J Invest Dermatol 115:1029-1033 2000..
  13. ncbi request reprint [Atopic patch test. Atopic eczema and allergy]
    U Darsow
    Klinische Kooperationsgruppe, Umweltdermatologie und Allerologie GSF TUM, Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, TU Munchen, Munich
    Hautarzt 54:930-6. 2003
    ..The characterization of a patient subgroup with relevant IgE-mediated allergy may lead to more efficient avoidance and perhaps even specific immunotherapy strategies in the management of atopic eczema...
  14. doi request reprint Influence of acupuncture on type I hypersensitivity itch and the wheal and flare response in adults with atopic eczema - a blinded, randomized, placebo-controlled, crossover trial
    F Pfab
    Department of Dermatology and Allergy, Technische Universitat Munchen, Munich, Germany
    Allergy 65:903-10. 2010
    ..We investigated the effect of acupuncture on type I hypersensitivity itch and skin reaction in a double-blind, randomized, placebo-controlled, crossover trial...
  15. ncbi request reprint Association of CARD15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults
    S Weidinger
    Department of Dermatology and Allergy Biederstein, Technical University Munich, Germany
    Clin Exp Allergy 35:866-72. 2005
    ..CARD15 polymorphisms have been associated with Crohn's disease. Recently, associations with atopic phenotypes have been reported in children...
  16. doi request reprint Temperature modulated histamine-itch in lesional and nonlesional skin in atopic eczema - a combined psychophysical and neuroimaging study
    F Pfab
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen, Munich, Germany
    Allergy 65:84-94. 2010
    ..The aim of this study was to use an evaluated itch stimulus model in lesional (LS) and nonlesional (NLS) atopic eczema (AE) skin and to characterize cerebral responses using functional magnetic resonance imaging (fMRI)...
  17. ncbi request reprint Central activation by histamine-induced itch: analogies to pain processing: a correlational analysis of O-15 H2O positron emission tomography studies
    A Drzezga
    Nuklearmedizinische Klinik, TU Munchen, Ismaninger Strasse 22, 81675, Munich, Germany
    Pain 92:295-305. 2001
    ..In contrast to pain activation studies, no subcortical (i.e. thalamic) activations were detected and correlation analyses suggest differences in subjective processing of the two sensations...
  18. doi request reprint Guidelines for treatment of atopic eczema (atopic dermatitis) Part II
    J Ring
    Department of Dermatology and Allergy Biederstein, Christine Kühne Center for Allergy Research and Education, Technische Universitat Munchen, Munich, Germany
    J Eur Acad Dermatol Venereol 26:1176-93. 2012
    ..Eczema school' educational programs have been proven to be helpful. Pruritus is targeted with the majority of the recommended therapies, but some patients need additional antipruritic therapies...
  19. ncbi request reprint Skin surface pH, stratum corneum hydration, trans-epidermal water loss and skin roughness related to atopic eczema and skin dryness in a population of primary school children
    B Eberlein-König
    Department of Dermatology and Allergy Biederstein, Technical University, Munich, Germany
    Acta Derm Venereol 80:188-91. 2000
    ..02). It is concluded that measurement of skin surface pH, corneometry and profilometry are useful non-invasive techniques to objectively assess skin dryness in epidemiological studies regarding atopic skin disease...
  20. pmc Acupuncture compared with oral antihistamine for type I hypersensitivity itch and skin response in adults with atopic dermatitis: a patient- and examiner-blinded, randomized, placebo-controlled, crossover trial
    F Pfab
    Department of Dermatology and Allergy, Technische Universitat Munchen, Munich, Germany
    Allergy 67:566-73. 2012
    ..Our study evaluated acupuncture and antihistamine itch therapy (cetirizine) on type I hypersensitivity itch and skin reaction in AD using a patient and examiner-blinded, randomized, placebo-controlled, crossover trial...
  21. doi request reprint Can immunoglobulin E-measurement replace challenge tests in allergic rhinoconjunctivits to grass pollen?
    J Huss-Marp
    ZAUM Center for Allergy and Environment, Division of Environmental Dermatology and Allergy, Helmholtz Center Munich, Technische Universitat Munchen, Munich, Germany
    Clin Exp Allergy 41:1116-24. 2011
    ..Timothy pollen-specific IgE (sIgE) determinations might assist in predicting the clinical reactivity in patients with allergic rhinoconjunctivitis (ARC)...
  22. ncbi request reprint Allergens. Heterogeneity of molecular sensitization profiles in grass pollen allergy--implications for immunotherapy?
    U Darsow
    Department of Dermatology and Allergy, Technische Universitat Munchen, Munich, Germany ZAUM Center for Allergy and Environment, Helmholtz Center Munich, Technische Universitat Munchen, Munich, Germany
    Clin Exp Allergy 44:778-86. 2014
    ..Data on molecular allergy diagnostics in adults with grass pollen allergy with regard to conjunctival and nasal provocation test outcome and specific immunotherapy are lacking to date...
  23. doi request reprint A new basophil activation test using CD63 and CCR3 in allergy to antibiotics
    B Eberlein
    Helmholtz Center Munich for Environmental Health TUM, Division of Environmental Dermatology and Allergology, Munich, Germany
    Clin Exp Allergy 40:411-8. 2010
    ..Flow cytometric basophil activation tests (BAT) have been developed as cellular tests for in vitro diagnosis of IgE-mediated reactions. Different markers and techniques have been used after stimulation with various allergens...
  24. ncbi request reprint The prevalence of positive reactions in the atopy patch test with aeroallergens and food allergens in subjects with atopic eczema: a European multicenter study
    U Darsow
    Department of Dermatology and Allergy Biederstein, Technical University Munich and Division of Environmental Dermatology and Allergy GSF TUM, Munich, Germany
    Allergy 59:1318-25. 2004
    ..The atopy patch test (APT) was proposed to evaluate IgE-mediated sensitizations in patients with atopic eczema (AE)...
  25. ncbi request reprint Influence of short-term exposure to airborne Der p 1 and volatile organic compounds on skin barrier function and dermal blood flow in patients with atopic eczema and healthy individuals
    J Huss-Marp
    Division of Environmental Dermatology and Allergy, GSF Technical University Munich, ZAUM Center for Allergy and Environment, Munich, Germany
    Clin Exp Allergy 36:338-45. 2006
    ..In human exposure studies, volatile organic compounds (VOCs) have been shown to cause exacerbations of allergic asthma whereas, no data concerning atopic eczema (AE) are available...
  26. ncbi request reprint Comparison of basophil activation tests using CD63 or CD203c expression in patients with insect venom allergy
    B Eberlein-König
    Department of Dermatology and Allergy Biederstein, Technical University Munich, Munich, Germany
    Allergy 61:1084-5. 2006
    ..Different activation markers (CD63 or CD203c) with distinct ways of regulation have been used after stimulation with various allergens...
  27. ncbi request reprint Atopic eczema and allergy
    J Ring
    Division of Environmental Dermatology and Allergy GSF TUM, Department of Dermatology and Allergy Biederstein, Technical University Munich, Biedersteiner Str 29, 80802 Munchen, Germany
    Curr Allergy Rep 1:39-43. 2001
    ..The new findings have given rise to a possible new classification of eczema/dermatitis. The concept of "patient management," including all aspects from avoidance to therapy, has gained acceptance...
  28. ncbi request reprint Atopic eczema: what's new?
    M Mohrenschlager
    Department of Dermatology and Allergy Biederstein, Technical University of Munich, Munich, Germany
    J Eur Acad Dermatol Venereol 20:503-11, 513; quiz 512. 2006
    ..Learning objective Upon completing this paper, the reader should be aware of new developments in AE, especially on nomenclature, prevention strategies, diagnostic tests, as well as therapeutic options...
  29. ncbi request reprint New aspects of itch pathophysiology: component analysis of atopic itch using the 'Eppendorf Itch Questionnaire'
    U Darsow
    Department of Dermatology and Allergy Biederstein, Technical University Munich, Munich, Germany
    Int Arch Allergy Immunol 124:326-31. 2001
    ..In conclusion, the complete description of itch has to consider different factors, which may be described on a more general level by three main components. Two of these are correlated with objective criteria of disease activity...
  30. doi request reprint Guidelines for treatment of atopic eczema (atopic dermatitis) part I
    J Ring
    Department of Dermatology and Allergy Biederstein, Christine Kühne Center for Allergy Research and Education, Technische Universitat Munchen, Munich, Germany
    J Eur Acad Dermatol Venereol 26:1045-60. 2012
    ..Eczema school' educational programs have been proven to be helpful. Pruritus is targeted with the majority of the recommended therapies, but some patients need additional antipruritic therapies...
  31. ncbi request reprint Neuroimmune interactions in the skin
    U Darsow
    Department of Dermatology and Allergy Biederstein, Technical University Munich, Germany
    Curr Opin Allergy Clin Immunol 1:435-9. 2001
    ..Novel strategies for therapy and prevention of chronicity may also result from understanding the role of increased secretion of nerve growth factor in atopic eczema and psoriasis...
  32. ncbi request reprint Review of the potential photo-cocarcinogenicity of topical calcineurin inhibitors: position statement of the European Dermatology Forum
    J Ring
    Department of Dermatology and Allergy Biederstein, Technische Universitat Munchen, Bavaria, Germany
    J Eur Acad Dermatol Venereol 19:663-71. 2005
    ..Available data suggest that long-term application of TCIs is safe, that there is no evidence of increased skin cancer risk and that it is ethical to treat patients with TCIs when indicated...
  33. ncbi request reprint Anaphylactic reaction to folic acid verified by provocational testing
    F Pfab
    Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, TU Munchen, Biedersteiner Strasse 29, 80802 Munchen, Germany
    Allergy 62:823-4. 2007
  34. doi request reprint Multiple basal cell carcinomas after long-term exposure to hydrazine: case report and review of the literature
    B A Aigner
    Department of Dermatology and Allergy am Biederstein, Technical University Munich, Munich, Germany
    Dermatology 221:300-2. 2010
    ..The present case report strongly suggests that there may be a correlation between the long-term exposure to hydrazine and an increased risk for multiple BCCs...
  35. pmc Association of a STAT 6 haplotype with elevated serum IgE levels in a population based cohort of white adults
    S Weidinger
    Department of Dermatology and Allergy, Technical University Munich, Biedersteiner St 29, 80802 Munich, Germany
    J Med Genet 41:658-63. 2004
    ..Among candidate genes in this region is STAT6 (signal transducer and activator of transcription), which is essential for Th2 cell differentiation, recruitment, and effector function...
  36. doi request reprint Atopic diseases, allergic sensitization, and exposure to traffic-related air pollution in children
    Verena Morgenstern
    Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, D 85764 Neuherberg, Germany
    Am J Respir Crit Care Med 177:1331-7. 2008
    ..In vitro studies, animal experiments, and human exposure studies have shown how ambient air pollution increases the risk of atopic diseases. However, results derived from observational studies are inconsistent...
  37. ncbi request reprint Standard skin prick testing and sensitization to inhalant allergens across Europe--a survey from the GALEN network
    L Heinzerling
    Department of Dermatology and Allergy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Allergy 60:1287-300. 2005
    ..This overview may serve as reference for the practising doctor and suggests a GA(2)LEN Pan-European core SPT panel...
  38. ncbi request reprint EAACI/GA2LEN position paper: present status of the atopy patch test
    K Turjanmaa
    Department of Dermatology, Tampere University Hospital, Tampere, Finland
    Allergy 61:1377-84. 2006
    ..This position paper also points out the need for future research on the clinical use of the APT...
  39. ncbi request reprint Anti-IL-5 recombinant humanized monoclonal antibody (mepolizumab) for the treatment of atopic dermatitis
    J M Oldhoff
    Department of Dermatology and Allergology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Allergy 60:693-6. 2005
    ..A monoclonal antibody to human interleukin-5 (mepolizumab) was developed for atopic diseases. This study was designed to study the effect of mepolizumab in AD...
  40. ncbi request reprint [Clinical classification of chronic pruritus. Interdisciplinary consensus proposal for a diagnostic algorithm]
    S Ständer
    Abteilung für klinische Neurodermatologie, Klinik und Poliklinik für Hautkrankheiten, Universitatsklinikum Munster
    Hautarzt 57:390-4. 2006
    ..The proposed clinical classification is oriented at the clinical appearance of the patients and differentiates between disorders with or without primary or secondary skin lesions...
  41. ncbi request reprint No effect of anti-interleukin-5 therapy (mepolizumab) on the atopy patch test in atopic dermatitis patients
    J M Oldhoff
    Department of Dermatology and Allergology, UMC Utrecht, Utrecht, The Netherlands
    Int Arch Allergy Immunol 141:290-4. 2006
    ..Previously, we reported that mepolizumab treatment did not result in clinical improvement in AD. The current study investigates the effect of mepolizumab therapy on the APT in the same patients...