Research Topics
Species | M Braun-FalcoSummaryAffiliation: Klinikum rechts der Isar Country: Germany Publications
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Detail Information
Publications
Recombinant adeno-associated virus (rAAV) vector-mediated cotransduction of CD70 and CD80 into human malignant melanoma cells results in an additive T-cell responseM Braun-Falco
Department of Dermatology, Technical University, Munich, Germany
Arch Dermatol Res 293:12-7. 2001..These results provide evidence that CD70 plays an additional role in T-cell activation and should be considered as a molecule of interest in the design of immune gene therapy strategies for the treatment of malignant melanoma...- Recombinant adeno-associated virus type 2-mediated gene transfer into human keratinocytes is influenced by both the ubiquitin/proteasome pathway and epidermal growth factor receptor tyrosine kinaseMarkus Braun-Falco
Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Division of Environmental Dermatology and Allergy, National Research Center for Environment and Health, Technische Universität München and GSF, Munich, Germany
Arch Dermatol Res 296:528-35. 2005..Treatment with quinazolines may increase rAAV-2 transduction of keratinocyte stem cells, which is important for gene therapy approaches to inherited diseases... - [Follicular drug reaction from cetuximab: a common side effect in the treatment of metastatic colon carcinoma]M Braun-Falco
Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universitat Munchen
Hautarzt 57:701-4. 2006..We present a typical case and discuss the important features of the follicular rash occurring after EGF-R inhibition... 
Histopathological characteristics of small diameter melanocytic naeviM Braun-Falco
Department of Dermatology and Allergology, Technical University Munich, 80802 Munich, Germany
J Clin Pathol 56:459-64. 2003..Because malignant melanomas and their precursors may arise in smaller lesions, a histological study of melanocytic lesions smaller than 4 mm in diameter was conducted to evaluate their histological appearance...- Linear spiradenoma with focal malignant transformationM Braun-Falco
Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universitat Munchen, Munchen, Germany
J Eur Acad Dermatol Venereol 17:308-12. 2003..In the presented case, the transformed area was excised. The patient is free of recurrence after 2 years... - Subepidermal cleft formation as a diagnostic marker for cutaneous malignant melanomaMarkus Braun-Falco
Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universitat Munchen, 80802 Munchen, Germany
Hum Pathol 36:412-5. 2005..The relative frequency of cleft formation allowed a highly significant differentiation between MM and benign melanocytic lesions. Clefts are a reliable diagnostic criterion in favor of MM... - [Palmoplantar vesicular lesions in childhood]M Braun-Falco
Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universitat Munchen, Munich
Hautarzt 54:156-9. 2003..Palmoplantar vesicles in children have various underlying causes, requiring different therapies. We evaluated the most common underlying diseases and determined simple criteria for differentiation... - [Scrotal leiomyoma]M Braun-Falco
Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universitat Munchen, Biedersteinerstrasse 29, 80802 Munchen
Hautarzt 53:258-60. 2002..This typical case demonstrates that leiomyomas should be considered in the differential diagnosis of scrotal tumors... - [Gene therapy concepts for promoting wound healing]M Braun-Falco
Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universität München Biedersteinerstr 29, 80802 Munchen
Hautarzt 53:238-43. 2002..This review discusses several methods of growth factor gene transfer into wound tissue and presents recent experimental results of gene therapy approaches in stimulating wound repair... - [Cylindrospiradenomas in Brooke-Spiegler syndrome]M Braun-Falco
Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universitat Munchen, Biedersteinerstrasse 29, 80802 Munchen
Hautarzt 52:1021-5. 2001..Moreover, at least for those cases of Brooke-Spiegler syndrome, where both tumors are found in immediate vicinity to each other, we propose the term cylindrospiradenoma... - Restoration of fatty aldehyde dehydrogenase deficiency in Sjögren-Larsson syndromeS Haug
Division of Environmental Dermatology and Allergy, GSF, National Research Center for Environment and Health, Neuherberg/Technical University Munich, Munich, Germany
Gene Ther 13:1021-6. 2006..These studies demonstrate the restoration of FALDH in human SLS cells supporting the concept of gene therapy as a potential future treatment option for SLS... - Association of urticaria pigmentosa with café-au-lait spots, neurofibromas and neurofibroma-like neoplasms: a mere coincidence?Matthias Möhrenschlager
Department of Dermatology and Allergy Biederstein, Technical University of Munich, Germany
Dermatology 206:297-302. 2003..Urticaria pigmentosa (UP) is characterized by dense aggregates of mast cells in the dermis. There is consistent evidence from the literature that mast cells may play a pathogenetic role in the development of neurofibromas and other tumors... - Fabry disease: recognition and management of cutaneous manifestationsMatthias Möhrenschlager
Department of Dermatology and Allergy Biederstein, Technical University of Munich, Munich, Germany
Am J Clin Dermatol 4:189-96. 2003..For the future, new treatment modalities, including enzyme replacement therapy, substrate deprivation strategies, and gene therapy offer extraordinary options for the cutaneous and visceral lesions in patients with Fabry disease... 
High-Definition Optical Coherence Tomography for the in vivo Detection of Demodex MitesT Maier
Department of Dermatology and Allergology, Ludwig Maximilian University of Munich, Munich, Germany
Dermatology 225:271-6. 2012..Conclusion: The innovative HD-OCT enables fast and noninvasive in vivo recognition of demodex mites and might become a useful tool in the diagnosis and treatment monitoring of demodex-related skin diseases...- Reflectance confocal microscopy in the diagnosis of partially and completely amelanotic melanoma: report on seven casesT Maier
Department of Dermatology and Allergology, Ludwig Maximilian University of Munich, Munich, Germany
J Eur Acad Dermatol Venereol 27:e42-52. 2013..The reflectance confocal microscopy (RCM) offers an additional possibility of an in vivo diagnosis of both pigmented and amelanotic melanoma lesions... - Morphology of basal cell carcinoma in high definition optical coherence tomography: en-face and slice imaging mode, and comparison with histologyT Maier
Department of Dermatology and Allergology, Ludwig Maximilian University of Munich, Munich, Germany
J Eur Acad Dermatol Venereol 27:e97-104. 2013..A new high definition OCT with high lateral and axial resolution in a horizontal (en-face) and vertical (slice) imaging mode offers additional information in the diagnosis of BCC and may potentially replace invasive diagnostic biopsies... - Erythema multiforme due to contact with laurel oilG I Athanasiadis
Department of Dermatology and Allergy, Technische Universitat, Munchen, Germany
Contact Dermatitis 57:116-8. 2007..The diagnosis was confirmed by the positive patch test to laurel oil, the histopathological studies of the lesions and the histopathological studies of the positive patch test to laurel oil... - Serine protease inhibitor lymphoepithelial Kazal type-related inhibitor tends to be decreased in atopic dermatitisD Roedl
ZAUM Center for Allergy and Environment, Division of Environmental Dermatology and Allergy, Helmholz Zentrum München, Technische Universitat Munchen, Munich, Germany
J Eur Acad Dermatol Venereol 23:1263-6. 2009..Analyses of an association between genetic polymorphisms of SPINK5 and atopic diseases revealed contradictory results. Herein, we assessed the role of LEKTI in AD at an expressional and functional level... - Systematic mutation screening of KRT5 supports the hypothesis that Galli-Galli disease is a variant of Dowling-Degos diseaseS Hanneken
Department of Dermatology, University Hospital Dusseldorf, Moorenstrasse 5, 40225 Dusseldorf, Germany
Br J Dermatol 163:197-200. 2010..Mutations in the keratin 5 gene (KRT5) have been identified in the majority of patients with DDD and in a small number of patients with GGD... - Galli-Galli disease: an unrecognized entity or an acantholytic variant of Dowling-Degos disease?M Braun-Falco
Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein, Technische Universitat Munchen, Biedersteinerstrasse 29, 80802 Munich, Germany
J Am Acad Dermatol 45:760-3. 2001..We report a typical case of Galli-Galli disease, which supports this concept... - Adeno-associated virus vectors are able to restore fatty aldehyde dehydrogenase-deficiency. Implications for gene therapy in Sjogren-Larsson syndromeStefanie Haug
Division of Environmental Dermatology and Allergy GSF - National Research Center for Environment and Health Neuherberg, Technical University Munich, Munich, Germany
Arch Dermatol Res 296:568-72. 2005..These results indicated that rAAV-2 vectors are able to restore FALDH-deficiency in a cell system resembling SLS. The findings give the first support to the concept that gene therapy might be a future option for the treatment of SLS... - Actinic keratosis in the en-face and slice imaging mode of high-definition optical coherence tomography and comparison with histologyT Maier
Department of Dermatology and Allergology, Ludwig Maximilian University of Munich, Frauenlobstr 9 11, D 80337 Munich, Germany
Br J Dermatol 168:120-8. 2013..An innovative high-definition (HD)-OCT with a horizontal (en-face) and vertical (slice) imaging mode offers additional information in the diagnosis of actinic keratosis (AK) and may potentially replace invasive diagnostic biopsies... - Combined malignant melanoma and basal cell carcinoma tumor of the intermingled typeMarkus Braun-Falco
Department of Dermatology, University Medical Center Freiburg, Freiburg, Germany
J Cutan Pathol 34:731-5. 2007..The combination of malignant melanoma (MM) and basal cell carcinoma (BCC) within a single tumor is an unusual finding... - Molecular diagnosis in dermatopathology: what makes sense, and what doesn'tMarkus Braun-Falco
Department of Dermatology, University Medical Center Freiburg, Freiburg, Germany
Exp Dermatol 18:12-23. 2009..Thus, they will broaden our armamentarium for diagnostic pathology. Herein, some key techniques will be reviewed and their applicability towards the diagnosis of dermatological diseases critically discussed... - Perifollicular protrusions--mid-dermal elastolysisAndreas Volz
Department of Dermatology, Freiburg, Germany
J Dtsch Dermatol Ges 7:68-9. 2009..The histopathologic correlate is a bandlike loss of elastic tissue within the mid-dermis.We present a typical case with prominent perifollicular protrusions... - Cutaneous metastases of visceral tumours: a reviewDorothee Nashan
Department of Dermatology, University Medical Center Freiburg, Hauptstr 7, 79104, Freiburg, Germany
J Cancer Res Clin Oncol 135:1-14. 2009..The clinical appearance and patterns of distribution of cutaneous metastases, the characterisation of clinical outcomes and available therapeutic options are compiled... - A painless nodule on the dorsum of the foot: hypopigmented blue nevus (HBN)Markus Braun-Falco
, , Munich, Germany
Arch Dermatol 138:1091-6. 2002 - An HIV-positive man with slowly enlarging nodules on the extremitiesMarkus Braun-Falco
Department of Dermatology, Ludwig-Albert University Freiburg, Freiburg, Germany
Clin Infect Dis 44:976, 1009-10. 2007 - Progress in the use of adeno-associated viral vectors for gene therapyHildegard Buning
Laboratorium für Molekulare Biologie, Genzentrum, Ludwig Maximilians Universitat Munchen, Germany
Cells Tissues Organs 177:139-50. 2004.... - Recurring localized scarlatiniform scaled erythema Féréol-BesnierMarkus Braun-Falco
Hautklinik der Albert Ludwigs Universität Freiburg, Freiburg, Deutschland
Dermatology 212:253-7. 2006..A typical case of the localized variant of this obscure disease is described and the common literature is reviewed... - [Band-like symmetric horizontal depression on both thighs]Frank Meiss
, , Germany
J Dtsch Dermatol Ges 5:1141-2. 2007 - Epidermotropic scrotal metastasis of colorectal cancerJuliane Reuter
Int J Colorectal Dis 22:1133-4. 2007 - Expression patterns of hair and epithelial keratins and transcription factors HOXC13, LEF1, and beta-catenin in a malignant pilomatricoma: a histological and immunohistochemical studyBernard Cribier
Department of Dermatology, University Hospital, Strasbourg, France
J Cutan Pathol 33:1-9. 2006..We speculate that the observed dominance of the epithelial differentiation pathway over the competing conventional shadow cell differentiation pathway may prevent massive calcification of the tumor... - Loss-of-function mutations in the keratin 5 gene lead to Dowling-Degos diseaseRegina C Betz
Institute of Human Genetics, University of Bonn, D 53111 Bonn, Germany
Am J Hum Genet 78:510-9. 2006....