S Bauer

Summary

Affiliation: Klinikum rechts der Isar
Country: Germany

Publications

  1. pmc Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
    S Bauer
    Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, 81675 Munich, Germany
    Proc Natl Acad Sci U S A 98:9237-42. 2001
  2. ncbi request reprint Bacterial CpG-DNA licenses TLR9
    S Bauer
    Institute for Medical Microbiology, Hygiene and Immunology, Trogerstrasse 9, 81675 Munich, Germany
    Curr Top Microbiol Immunol 270:145-54. 2002
  3. ncbi request reprint Toll-like receptors: cellular signal transducers for exogenous molecular patterns causing immune responses
    C J Kirschning
    Institute of Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Germany
    Int J Med Microbiol 291:251-60. 2001
  4. ncbi request reprint TNFalpha-mediated induction of PAI-1 restricts invasion of HTR-8/SVneo trophoblast cells
    A V Huber
    Department of Obstetrics and Gynecology, Medical University of Vienna, AKH, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Placenta 27:127-36. 2006
  5. ncbi request reprint Expression pattern of collagen XVIII and its cleavage product, the angiogenesis inhibitor endostatin, at the fetal-maternal interface
    J Pollheimer
    Department of Obstetrics and Gynecology, Medical University of Vienna, AKH, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Placenta 25:770-9. 2004
  6. ncbi request reprint Identification and characterisation of regions in the cellular protein LaXp180 and the Listeria monocytogenes surface protein ActA necessary for the interaction of the two proteins
    S Bauer
    Lehrstuhl fur Mikrobiologie, Theodor Boveri Institut für Biowissenschaften der Universität Würzburg, Am Hubland, 97074 Wurzburg, Germany
    Mol Genet Genomics 268:607-17. 2003
  7. ncbi request reprint Production of pro- and anti-inflammatory cytokines of human placental trophoblasts in response to pathogenic bacteria
    G Griesinger
    Department of Obstetrics and Gynecology, University of Vienna, Vienna, Austria
    J Soc Gynecol Investig 8:334-40. 2001
  8. ncbi request reprint P2X(2), P2X(2-2) and P2X(5) receptor subunit expression and function in rat thoracolumbar sympathetic neurons
    H Schädlich
    Rudolf Boehm Institute of Pharmacology and Toxicology, University of Leipzig, Leipzig, Germany
    J Neurochem 79:997-1003. 2001
  9. ncbi request reprint Somatostatin inhibits stem cell factor messenger RNA expression by Sertoli cells and stem cell factor-induced DNA synthesis in isolated seminiferous tubules
    I Goddard
    , , F-69921 Oullins, France
    Biol Reprod 65:1732-42. 2001
  10. ncbi request reprint The surrogate light chain in B-cell development
    F Melchers
    Basel Institute for Immunology, Switzerland
    Immunol Today 14:60-8. 1993

Collaborators

  • Jie Wu
  • H Wagner
  • C J Kirschning
  • G B Lipford
  • H Hacker
  • S Akira
  • Arne Ludwig
  • H J Mollenkopf
  • M Kuhn
  • Lewis L Lanier
  • P Jay
  • A Huber
  • P Husslein
  • M Knöfler
  • G Griesinger
  • E E Baiyee
  • J Pollheimer
  • I Goddard
  • H Schädlich
  • L Saleh
  • N Mueller
  • M E Percy
  • V Groh
  • S Lendemans
  • H Grosse-Wilde
  • S Flohe
  • E Kreuzfelder
  • J D Aplin
  • C Renner
  • J L Berge-lefranc
  • J Grosche
  • F Lopez
  • A Gougeon
  • G Burnstock
  • C Susini
  • N Giannetti
  • S Krantic
  • H Franke
  • K Wirkner
  • M Benahmed
  • P Illes
  • A Reichenbach
  • C Allgaier
  • H Helmer
  • R Vasicek
  • H Strohmer
  • S Wong
  • A Steinle
  • M Dhar
  • J G Joshi
  • V M Chauthaiwale
  • M D Perry
  • N Liaghati-Nasseri
  • T Spies
  • M Pfreundschuh
  • S Ohnesorge
  • U Sahin
  • J P Pfitzenmeier
  • K Gerlach
  • G Held
  • P Berta
  • A Massacrier
  • M Fontes
  • M G Mattei
  • F Melchers
  • P Cau
  • C Marsollier
  • H Karasuyama
  • N Sakaguchi
  • A Kudo
  • D Haasner
  • B Jameson
  • A Rolink

Detail Information

Publications19

  1. pmc Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
    S Bauer
    Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, 81675 Munich, Germany
    Proc Natl Acad Sci U S A 98:9237-42. 2001
    ..The optimal CpG motif for hTLR9 was GTCGTT, whereas the optimal murine sequence was GACGTT. Overall, these data suggest that hTLR9 conveys CpG-DNA responsiveness to human cells by directly engaging immunostimulating CpG-DNA...
  2. ncbi request reprint Bacterial CpG-DNA licenses TLR9
    S Bauer
    Institute for Medical Microbiology, Hygiene and Immunology, Trogerstrasse 9, 81675 Munich, Germany
    Curr Top Microbiol Immunol 270:145-54. 2002
    ..This review focuses on TLR9 which is an essential component for the recognition of bacterial CpG-DNA. Expression of TLR9 and structural consideration as well as direct ligand interaction of TLR9 and CpG-DNA are discussed...
  3. ncbi request reprint Toll-like receptors: cellular signal transducers for exogenous molecular patterns causing immune responses
    C J Kirschning
    Institute of Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Germany
    Int J Med Microbiol 291:251-60. 2001
    ..Further understanding of recognition and cellular signaling activated through the ancient host defense system represented by Toll will eventually lead to means for its therapeutic modulation...
  4. ncbi request reprint TNFalpha-mediated induction of PAI-1 restricts invasion of HTR-8/SVneo trophoblast cells
    A V Huber
    Department of Obstetrics and Gynecology, Medical University of Vienna, AKH, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Placenta 27:127-36. 2006
    ..The data suggest that TNFalpha restricts trophoblast invasion mainly by increasing the expression of PAI-1. Induction of the inhibitor may involve TNFalpha-stimulated activation of NFkappaB...
  5. ncbi request reprint Expression pattern of collagen XVIII and its cleavage product, the angiogenesis inhibitor endostatin, at the fetal-maternal interface
    J Pollheimer
    Department of Obstetrics and Gynecology, Medical University of Vienna, AKH, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Placenta 25:770-9. 2004
    ..Moreover, supplementation of recombinant endostatin increased MMP-2 expression in villous explant cultures and SGHPL-5 cells suggesting that the inhibitor may modulate extravillous trophoblast differentiation...
  6. ncbi request reprint Identification and characterisation of regions in the cellular protein LaXp180 and the Listeria monocytogenes surface protein ActA necessary for the interaction of the two proteins
    S Bauer
    Lehrstuhl fur Mikrobiologie, Theodor Boveri Institut für Biowissenschaften der Universität Würzburg, Am Hubland, 97074 Wurzburg, Germany
    Mol Genet Genomics 268:607-17. 2003
    ....
  7. ncbi request reprint Production of pro- and anti-inflammatory cytokines of human placental trophoblasts in response to pathogenic bacteria
    G Griesinger
    Department of Obstetrics and Gynecology, University of Vienna, Vienna, Austria
    J Soc Gynecol Investig 8:334-40. 2001
    ..Induction of both inflammation-promoting and inflammation-inhibiting cytokines by bacterial products could play a role in modulating the inflammatory response associated with chorioamnionitis...
  8. ncbi request reprint P2X(2), P2X(2-2) and P2X(5) receptor subunit expression and function in rat thoracolumbar sympathetic neurons
    H Schädlich
    Rudolf Boehm Institute of Pharmacology and Toxicology, University of Leipzig, Leipzig, Germany
    J Neurochem 79:997-1003. 2001
    ..Apparently there exist two types of P2X(2) receptor-bearing sympathetic neurons: one major population expressing the unspliced isoform and another minor population expressing the P2X(2-2) splice variant...
  9. ncbi request reprint Somatostatin inhibits stem cell factor messenger RNA expression by Sertoli cells and stem cell factor-induced DNA synthesis in isolated seminiferous tubules
    I Goddard
    , , F-69921 Oullins, France
    Biol Reprod 65:1732-42. 2001
    ..Combined RT-PCR and immunohistochemical approaches point toward spermatogonia and Leydig cells as the source of testicular SRIF. These data argue in favor of paracrine/autocrine SRIF actions in testis...
  10. ncbi request reprint The surrogate light chain in B-cell development
    F Melchers
    Basel Institute for Immunology, Switzerland
    Immunol Today 14:60-8. 1993
    ..Here, Fritz Melchers and colleagues review the structures of the VpreB and lambda 5 genes in mouse and their relatives in humans, describe their pattern of expression, and speculate on their possible evolution and functions...
  11. ncbi request reprint Promoter elements and transcription factors involved in differentiation-dependent human chorionic gonadotrophin-alpha messenger ribonucleic acid expression of term villous trophoblasts
    M Knöfler
    Department of Obstetrics and Gynecology, University of Vienna, Austria
    Endocrinology 141:3737-48. 2000
    ..We conclude that differentiation-dependent transcription of the CGalpha gene in villous trophoblasts is mainly governed by increasing expression of AP-2alpha and PKA-dependent phosphorylation of CREB-1 and ATF-1...
  12. ncbi request reprint An activating immunoreceptor complex formed by NKG2D and DAP10
    J Wu
    DNAX Research Institute, 901 California Avenue, Palo Alto, CA 94304, USA
    Science 285:730-2. 1999
    ..Thus, NKG2D-DAP10 receptor complexes may activate NK and T cell responses against MICA-bearing tumors...
  13. ncbi request reprint Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    S Bauer
    Fred Hutchinson Cancer Research Center, Clinical Research Division, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Science 285:727-9. 1999
    ..These results define an activating immunoreceptor-MHC ligand interaction that may promote antitumor NK and T cell responses...
  14. ncbi request reprint Iron metabolism and human ferritin heavy chain cDNA from adult brain with an elongated untranslated region: new findings and insights
    M E Percy
    Department of Physiology, University of Toronto, Ontario, Canada
    Analyst 123:41-50. 1998
    ..Possible functions for ferritin H protein derived from the novel message and for the elongated 3'UTR and 5'UTR are discussed...
  15. ncbi request reprint Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells
    V Groh
    Fred Hutchinson Cancer Research Center, Clinical Research Division, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Science 279:1737-40. 1998
    ..Thus, these molecules may broadly regulate protective responses by the Vdelta1 gammadelta T cells in the epithelium of the intestinal tract...
  16. ncbi request reprint RP1, a new member of the adenomatous polyposis coli-binding EB1-like gene family, is differentially expressed in activated T cells
    C Renner
    Med Klinik I, University of Saarlandes, Homburg, Germany
    J Immunol 159:1276-83. 1997
    ....
  17. ncbi request reprint Characterization of the human jumonji gene
    J L Berge-lefranc
    INSERM U406, Marseille, France
    Hum Mol Genet 5:1637-41. 1996
    ..In view of these observations, we propose JMJ as a candidate gene for developmental defects of the central nervous system in the human. The human JMJ gene maps at position 6p24-6p23...
  18. ncbi request reprint SlyA, a regulatory protein from Salmonella typhimurium, induces a haemolytic and pore-forming protein in Escherichia coli
    A Ludwig
    Biozentrum, Universitat Wurzburg, Theodor Boveri Institut, Mikrobiologie Am Hubland, Germany
    Mol Gen Genet 249:474-86. 1995
    ..slyA- and slyB-related genes were also obtained by PCR from E. coli, Shigella sp. and Citrobacter diversus but not from several other gram-negative bacteria tested...
  19. pmc Expression and function of Toll-like receptor 9 in severely injured patients prone to sepsis
    E E Baiyee
    Institut fuer Immunologie, Universitaetsklinikum Essen, Essen, Germany
    Clin Exp Immunol 145:456-62. 2006
    ..Immunosuppression in the early phase after trauma seems not to be associated with a disturbed sensing of bacterial DNA...