Martin Schaefer

Summary

Affiliation: Kliniken Essen-Mitte
Country: Germany

Publications

  1. doi request reprint Management of mental health problems prior to and during treatment of hepatitis C virus infection in patients with drug addiction
    Martin Schaefer
    Department of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen Mitte, Essen, Germany
    Clin Infect Dis 57:S111-7. 2013
  2. doi request reprint Hepatitis C infection, antiviral treatment and mental health: a European expert consensus statement
    Martin Schaefer
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    J Hepatol 57:1379-90. 2012
  3. doi request reprint Escitalopram for the prevention of peginterferon-α2a-associated depression in hepatitis C virus-infected patients without previous psychiatric disease: a randomized trial
    Martin Schaefer
    Department of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen Mitte, Henricistr 92, 45136 Essen, Germany
    Ann Intern Med 157:94-103. 2012
  4. ncbi request reprint Hepatitis C treatment in patients with drug addiction: clinical management of interferon-alpha-associated psychiatric side effects
    Martin Schaefer
    Department of Psychiatry and Psychotherapy, Kliniken Essen Mitte, Ev Huyssenstift, Essen, Germany
    Curr Drug Abuse Rev 1:177-87. 2008
  5. ncbi request reprint Hepatitis C treatment in "difficult-to-treat" psychiatric patients with pegylated interferon-alpha and ribavirin: response and psychiatric side effects
    Martin Schaefer
    Charite Universitatsmedizin Berlin, Klinik und Poliklinik für Psychiatrie und Psychotherapie Campus Charité Mitte, Berlin, Germany
    Hepatology 46:991-8. 2007
  6. ncbi request reprint Pretreatment levels of sTNF-R1 and sIL-6R are associated with a higher vulnerability for IFN-alpha-induced depressive symptoms in patients with malignant melanoma
    Astrid Friebe
    Department of Psychiatry, Charite, Campus Mitte, Berlin, Germany
    J Immunother 30:333-7. 2007
  7. doi request reprint Health-related quality of life before and during adjuvant interferon-α treatment for patients with malignant melanoma (DeCOG-trial)
    Susanne Ziefle
    Department of Psychiatry, Charite Campus Mitte, Charite University Medicine Berlin, Germany
    J Immunother 34:403-8. 2011
  8. doi request reprint Three cases of successful tryptophan add-on or monotherapy of hepatitis C and IFNalpha-associated mood disorders
    Martin Schaefer
    Department of Psychiatry, Charite Universitatsmedizin, Berlin, Germany
    Psychosomatics 49:442-6. 2008
  9. ncbi request reprint Prevention of interferon-alpha associated depression in psychiatric risk patients with chronic hepatitis C
    Martin Schaefer
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    J Hepatol 42:793-8. 2005
  10. ncbi request reprint Adherence and mental side effects during hepatitis C treatment with interferon alfa and ribavirin in psychiatric risk groups
    Martin Schaefer
    Department of Psychiatry, Charite, Humboldt University, Berlin, Germany
    Hepatology 37:443-51. 2003

Collaborators

Detail Information

Publications22

  1. doi request reprint Management of mental health problems prior to and during treatment of hepatitis C virus infection in patients with drug addiction
    Martin Schaefer
    Department of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen Mitte, Essen, Germany
    Clin Infect Dis 57:S111-7. 2013
    ..Other, more rare but severe complications such as mania, psychotic symptoms, or delirium need individual psychiatric interventions. ..
  2. doi request reprint Hepatitis C infection, antiviral treatment and mental health: a European expert consensus statement
    Martin Schaefer
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    J Hepatol 57:1379-90. 2012
    ..The summarised current knowledge about mental health changes before and during antiviral treatment should improve interdisciplinary management of HCV infected patients...
  3. doi request reprint Escitalopram for the prevention of peginterferon-α2a-associated depression in hepatitis C virus-infected patients without previous psychiatric disease: a randomized trial
    Martin Schaefer
    Department of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen Mitte, Henricistr 92, 45136 Essen, Germany
    Ann Intern Med 157:94-103. 2012
    ..It is unclear whether antidepressants can prevent IFN-induced depression in patients without psychiatric risk factors...
  4. ncbi request reprint Hepatitis C treatment in patients with drug addiction: clinical management of interferon-alpha-associated psychiatric side effects
    Martin Schaefer
    Department of Psychiatry and Psychotherapy, Kliniken Essen Mitte, Ev Huyssenstift, Essen, Germany
    Curr Drug Abuse Rev 1:177-87. 2008
    ..Overall, the psychiatric adverse event profile of interferon-based therapy for HCV-infected patients with drug addiction is considerable and requires active management and knowledge about psychiatric medical therapy...
  5. ncbi request reprint Hepatitis C treatment in "difficult-to-treat" psychiatric patients with pegylated interferon-alpha and ribavirin: response and psychiatric side effects
    Martin Schaefer
    Charite Universitatsmedizin Berlin, Klinik und Poliklinik für Psychiatrie und Psychotherapie Campus Charité Mitte, Berlin, Germany
    Hepatology 46:991-8. 2007
    ....
  6. ncbi request reprint Pretreatment levels of sTNF-R1 and sIL-6R are associated with a higher vulnerability for IFN-alpha-induced depressive symptoms in patients with malignant melanoma
    Astrid Friebe
    Department of Psychiatry, Charite, Campus Mitte, Berlin, Germany
    J Immunother 30:333-7. 2007
    ..In contrast to the initial hypothesis, patients characterized by high sTNF-R1 and low sIL-6R baseline levels, indicating an anti-inflammatory condition before therapy, had a higher vulnerability for depression during IFN-alpha therapy...
  7. doi request reprint Health-related quality of life before and during adjuvant interferon-α treatment for patients with malignant melanoma (DeCOG-trial)
    Susanne Ziefle
    Department of Psychiatry, Charite Campus Mitte, Charite University Medicine Berlin, Germany
    J Immunother 34:403-8. 2011
    ..Specific psychosocial care should be offered especially for patients who report lower HRQoL and emotional problems before treatment to prevent early discontinuation...
  8. doi request reprint Three cases of successful tryptophan add-on or monotherapy of hepatitis C and IFNalpha-associated mood disorders
    Martin Schaefer
    Department of Psychiatry, Charite Universitatsmedizin, Berlin, Germany
    Psychosomatics 49:442-6. 2008
    ..Interferon-alpha (IFN(alpha))-associated mood disorder is a major complication of treatment for chronic hepatitis C...
  9. ncbi request reprint Prevention of interferon-alpha associated depression in psychiatric risk patients with chronic hepatitis C
    Martin Schaefer
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    J Hepatol 42:793-8. 2005
    ..We prospectively studied the efficacy of a pre-emptive treatment with the antidepressant citalopram to prevent depression during hepatitis C treatment with pegylated IFN-alpha-2b plus ribavirin...
  10. ncbi request reprint Adherence and mental side effects during hepatitis C treatment with interferon alfa and ribavirin in psychiatric risk groups
    Martin Schaefer
    Department of Psychiatry, Charite, Humboldt University, Berlin, Germany
    Hepatology 37:443-51. 2003
    ..Preexisting psychiatric disorders or present methadone substitution should no longer be regarded as contraindications to treatment of chronic hepatitis C with IFN-alpha and ribavirin in an interdisciplinary setting...
  11. doi request reprint Efficacy and safety of levetiracetam for the prevention of alcohol relapse in recently detoxified alcohol-dependent patients: a randomized trial
    Christoph Richter
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    J Clin Psychopharmacol 32:558-62. 2012
    ..Antiepileptics have been shown to reduce alcohol intake or to prevent relapse in patients with alcoholism...
  12. ncbi request reprint Treatment of chronic hepatitis C in patients with drug dependence: time to change the rules?
    Martin Schaefer
    Department of Psychiatry CCM, Charite University Medicine Berlin, Berlin, Germany
    Addiction 99:1167-75. 2004
    ....
  13. ncbi request reprint Current schizophrenia drugs: efficacy and side effects
    Michael Krebs
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Schumannstr 20 21, D 10117 Berlin, Germany
    Expert Opin Pharmacother 7:1005-16. 2006
    ....
  14. doi request reprint Depressive mood changes and psychiatric symptoms during 12-month low-dose interferon-alpha treatment in patients with malignant melanoma: results from the multicenter DeCOG trial
    Sarah Heinze
    Department of Psychiatry, Charite Campus Mitte, Charite University Medicine, Berlin, Germany
    J Immunother 33:106-14. 2010
    ..A higher pretreatment depression score was found to be a risk factor for an early drop-out during therapy. Pretreatment screening and an interdisciplinary care of the patients is recommended...
  15. ncbi request reprint Cognitive impairment in patients with chronic hepatitis treated with interferon alpha (IFNalpha): results from a prospective study
    Klaus Lieb
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstr 5, 79104 Freiburg, Germany
    Eur Psychiatry 21:204-10. 2006
    ..In addition to depression and anxiety, IFN-alpha associated cognitive impairment significantly affects patient's mental health and quality of life...
  16. ncbi request reprint Levetiracetam for the treatment of alcohol withdrawal syndrome: a multicenter, prospective, randomized, placebo-controlled trial
    Christoph Richter
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Germany
    J Clin Psychopharmacol 30:720-5. 2010
    ..We therefore investigated the safety and efficacy of levetiracetam (LV), a newer antiepileptic with a potentially favorable adverse-effect profile, for the treatment of AWS...
  17. ncbi request reprint Correlation between sICAM-1 and depressive symptoms during adjuvant treatment of melanoma with interferon-alpha
    Martin Schaefer
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    Brain Behav Immun 18:555-62. 2004
    ..367, p = .018). Our data provides evidence for an association between the induction of sICAM-1 and the development of symptoms of depression during IFN-alpha treatment, possibly by enhancing BBB-permeability...
  18. ncbi request reprint Psychiatric symptoms and cognitive dysfunction caused by Epstein-Barr virus-induced encephalitis
    Joachim Behr
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, 10117 Berlin, Germany
    Eur Psychiatry 21:521-2. 2006
    ..Clinical recovery and clearance of cerebrospinal fluid EBV DNA appeared following ganciclovir treatment within 6 weeks...
  19. doi request reprint Administration of interferon-alpha in mice provokes peripheral and central modulation of immune cells, accompanied by behavioral effects
    Arif S Orsal
    Neuropsychiatry and Laboratory of Molecular Psychiatry, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Neuropsychobiology 58:211-22. 2008
    ..Unfortunately, the mechanisms underlying IFN-alpha-induced depression are still not well understood...
  20. doi request reprint Interaction of hippocampal volume and N-acetylaspartate concentration deficits in schizophrenia: a combined MRI and 1H-MRS study
    Andreas Arthur Klär
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    Neuroimage 53:51-7. 2010
    ..However, the possible interaction between regional NAA reduction and volume deficits has been targeted only marginally in previous investigations...
  21. ncbi request reprint Zotepine loading in acute and severely manic patients: a pilot study
    Benedikt Amann
    Department of Psychiatry, University LMU Munich, Germany
    Bipolar Disord 7:471-6. 2005
    ..The aim of this study was to test the first-generation atypical antipsychotic zotepine regarding its antimanic efficacy, tolerability and to find an adequate dosage for a loading strategy...
  22. ncbi request reprint Neuroprotective agents in schizophrenia and affective disorders
    Michael Krebs
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    Expert Opin Pharmacother 7:837-48. 2006
    ..This paper reviews the current options for neuroprotective treatment approaches focusing on schizophrenia and affective disorders...