Research Topics
| T DanneSummaryAffiliation: Kinderkrankenhaus auf der Bult Country: Germany Publications
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Detail Information
Publications
Current practice of insulin pump therapy in children and adolescents - the Hannover recipeThomas Danne
Diabeteszentrum für Kinder und Jugendliche, Kinderkrankenhaus auf der Bult, Janusz Korczak Allee, Hannover, Germany
Pediatr Diabetes 7:25-31. 2006..This feature can be helpful, if a trustful relationship between the diabetes team and the family is established...
Insulin treatment. ISPAD clinical practice consensus guidelines 2006-2007Hans-Jacob Bangstad
Department of Pediatrics, Ulleval University Hospital, Oslo, Norway
Pediatr Diabetes 8:88-102. 2007
Current challenges in children with type 1 diabetesThomas Danne
Pediatr Diabetes 8:3-5. 2007
New developments in the treatment of type 1 diabetes in childrenThomas Danne
Kinderkrankenhaus auf der Bult, Hannover, Germany
Arch Dis Child 92:1015-9. 2007
[Type 1 diabetes in children and adolescents--new strategies in management and treatment]Olga Kordonouri
Kinder und Jugendliche, Kinderkrankenhaus auf der Bult, Janusz Korczak Allee 1, Hannover
Med Monatsschr Pharm 31:200-6; quiz 207-8. 2008..Sensor-based insulin treatment is likely to have a significant impact on paediatric diabetes therapy and education in the future...
Criteria for Centers of Reference for pediatric diabetes--a European perspectiveThomas Danne
Kinder und Jugendlkrankenhaus AUF DER BULT, Janusz Korczak Allee 12, Hannover, Germany
Pediatr Diabetes 13:62-75. 2012..The SWEET project hopes to extend from the initial group of centers within countries, throughout Europe, and beyond with the help of the ISPAD network...
Current issues in paediatric diabetology: introduction to Meet-the-Expert sessionsT Danne
, Kinderkrankenhaus auf der Bult, Hannover Medical School, Germany
Horm Res 57:91-2. 2002
Pharmacokinetics, prandial glucose control, and safety of insulin glulisine in children and adolescents with type 1 diabetesThomas Danne
Kinderkrankenhaus auf der Bult, Diabetes Zentrum für Kinder und Jugendliche, Janusz Korczak Allee 12, 30173 Hannover, Germany
Diabetes Care 28:2100-5. 2005....
A cross-sectional international survey of continuous subcutaneous insulin infusion in 377 children and adolescents with type 1 diabetes mellitus from 10 countriesThomas Danne
Kinderkrankenhaus auf der Bult, Hannover, Germany
Pediatr Diabetes 6:193-8. 2005....
Reducing glycaemic variability in type 1 diabetes self-management with a continuous glucose monitoring system based on wired enzyme technologyT Danne
Kinderkrankenhaus auf der Bult, Janusz Korczak Allee 12, 30173 Hannover, Germany
Diabetologia 52:1496-503. 2009..This study was designed to investigate the use and impact of a continuous glucose monitoring system (the FreeStyle Navigator) under home-use conditions in the self-management of type 1 diabetes...
Real-time glucose sensors in children and adolescents with type-1 diabetesThomas Danne
Kinderkrankenhaus auf der Bult, Medizinische Hochschule Hannover, Hannover, Germany
Horm Res 70:193-202. 2008....
Insulin detemir is characterized by a more reproducible pharmacokinetic profile than insulin glargine in children and adolescents with type 1 diabetes: results from a randomized, double-blind, controlled trialThomas Danne
Center for Pediatric Endocrinology and Diabetes, Kinderkrankenhaus auf der Bult, Hannover Medical School, Hannover, Germany
Pediatr Diabetes 9:554-60. 2008..This indicates a less variable absorption with detemir, which is expected to be associated with a more predictable therapeutic effect also in this population...
Establishing glycaemic control with continuous subcutaneous insulin infusion in children and adolescents with type 1 diabetes: experience of the PedPump Study in 17 countriesT Danne
Kinderkrankenhaus auf der Bult, Hanover, Janusz Korczak Allee 12, 30173 Hanover, Germany
Diabetologia 51:1594-601. 2008..To assess the use of paediatric continuous subcutaneous infusion (CSII) under real-life conditions by analysing data recorded for up to 90 days and relating them to outcome...
Flexibility of rapid-acting insulin analogues in children and adolescents with diabetes mellitusThomas Danne
Department of General Pediatrics, Center for Pediatric Endocrinology and Diabetology, Children s Hospital Auf der Bult, Hannover Medical School, Hannover, Germany
Clin Ther 29:S145-52. 2007..Achieving glycosylated hemoglobin control is a very important aim, but quality-of-life concerns for the child and the family should also have high priority in the management of pediatric DM...
Paediatric diabetes: achieving practical, effective insulin therapy in type 1 and type 2 diabetesT Danne
Diabetes Zentrum für Kinder und Jugendliche, Kinderkrankenhaus auf der Bult, Hannover, Germany
Acta Paediatr 96:1560-70. 2007....
Parental preference of prandial insulin aspart compared with preprandial human insulin in a basal-bolus scheme with NPH insulin in a 12-wk crossover study of preschool children with type 1 diabetesThomas Danne
Kinderkrankenhaus auf der Bult, Hannover, Germany
Pediatr Diabetes 8:278-85. 2007..regular human insulin (HI) plus NPH] in preschool children with type 1 diabetes...
Use of technology to potentially preserve C-Peptide in type 1 diabetes mellitusThomas Danne
The Bult Diabetes Center for Children and Adolescents, Kinderkrankenhaus auf der Bult, Hannover, Germany
Pediatr Endocrinol Rev 7:396-400. 2010..This may preserve C-peptide and improve outcomes both with and without additional immunomodulatory therapy at the onset of T1DM...
New insulins and insulin therapyT Danne
Diabetes Zentrum für Kinder and Jugendliche, Kinderkrankenhaus auf der Bult, Hannover, Germany
Int J Clin Pract 65:26-30. 2011..This has been done by means of PubMed searches as well as a review of abstracts of the recent large international diabetes meetings such as ADA, EASD and ISPAD...
Insulin detemir is characterized by a consistent pharmacokinetic profile across age-groups in children, adolescents, and adults with type 1 diabetesThomas Danne
Kinderkrankenhaus auf der Bult, Hannover, Germany
Diabetes Care 26:3087-92. 2003..Comparisons were also made with NPH insulin to determine any between-treatment difference in the effect of age on pharmacokinetic profile...
A comparison of postprandial and preprandial administration of insulin aspart in children and adolescents with type 1 diabetesThomas Danne
Kinderkrankenhaus auf der Bult, Diabetes Zentrum für Kinder und Jugendliche, Hannover, Germany
Diabetes Care 26:2359-64. 2003..The aim of this study was to compare the glycemic control of preprandial versus postprandial injections of the new rapid-acting insulin analogue aspart in children and adolescents with type 1 diabetes...
Persistent differences among centers over 3 years in glycemic control and hypoglycemia in a study of 3,805 children and adolescents with type 1 diabetes from the Hvidøre Study GroupT Danne
Charite Children s Hospital, Humboldt University, Berlin, Germany
Diabetes Care 24:1342-7. 2001....
Prevention of hypoglycemia by using low glucose suspend function in sensor-augmented pump therapyThomas Danne
Children s Hospital on the Bult, Hannover, Germany
Diabetes Technol Ther 13:1129-34. 2011..In a prospective study, we investigated the effect of the LGS algorithm on the frequency of hypoglycemia in children and adolescents with type 1 diabetes under real-life conditions...
Experience with insulin analogues in childrenThomas Danne
Diabetes Zentrum für Kinder und Jugendliche, Kinderkrankenhaus auf der Bult, Hannover, Germany
Horm Res 57:46-53. 2002....
Sensor-augmented pump therapy from the diagnosis of childhood type 1 diabetes: results of the Paediatric Onset Study (ONSET) after 12 months of treatmentO Kordonouri
Bult Diabetes Centre for Children and Adolescents, Kinderkrankenhaus auf der Bult, Janusz Korczak Allee 12, D 30173 Hannover, Germany
Diabetologia 53:2487-95. 2010....
[Insulin pump treatment in children and adolescents with type 1 diabetes]C Bittner
Kinderkrankenhaus auf der Bult, , Hannover
MMW Fortschr Med 146:35-7. 2004
[Clinical parameters for molecular testing of Maturity Onset Diabetes of the Young (MODY)]N Datz
Diabeteszentrum für Kinder und Jugendliche, Kinderkrankenhaus auf der Bult, Hannover, Deutschland
Dtsch Med Wochenschr 136:1111-5. 2011..Aim of this study was to evaluate clinical parameters for an efficient screening...
Treatment with insulin glargine reduces asymptomatic hypoglycemia detected by continuous subcutaneous glucose monitoring in children and adolescents with type 1 diabetesDorothee Deiss
Clinic of General Pediatrics, Otto Heubner Centrum, Charite, Campus Virchow Klinikum, Humboldt University, Berlin, Germany
Pediatr Diabetes 8:157-62. 2007....
Autoantibodies to tissue transglutaminase are sensitive serological parameters for detecting silent coeliac disease in patients with Type 1 diabetes mellitusO Kordonouri
Department of Paediatrics, Charite, Humboldt University, Berlin, Germany
Diabet Med 17:441-4. 2000..To investigate the clinical significance of the determination of IgA antibodies to tissue transglutaminase (tTG) for the detection of silent coeliac disease in patients with Type 1 diabetes mellitus...
Genetic risk markers related to diabetes-associated autoantibodies in young patients with type 1 diabetes in berlin, GermanyO Kordonouri
Diabetes Centre for Children and Adolescents, Children s Hospital Auf der Bult, Hannover, Germany
Exp Clin Endocrinol Diabetes 118:245-9. 2010..To determine the prevalence of genetic risk markers of type 1 diabetes (T1D) in children diagnosed at a single centre in Germany and to assess their relation to diabetes-associated autoantibodies...
Prevalence of latex-specific IgE antibodies in atopic and nonatopic children with type I diabetesT Danne
Children s Hospital, Charite Virchow Clinic, Humboldt University, Berlin, Germany
Diabetes Care 20:476-8. 1997..The potential induction of allergic sensitization to latex from insulin vial tops stimulated an investigation of the prevalence of specific IgE antibodies to latex in serum and the relationship to atopic disease in children with diabetes...
Prerequisites for age-appropriate education in type 1 diabetes: a model programme for paediatric diabetes education in GermanyKarin Lange
Department of Medical Psychology, Hannover Medical School, Hannover, Germany
Pediatr Diabetes 8:63-71. 2007..In the context of the Disease-Management-Program for Type 1 Diabetes in Germany these programmes for young people were certified and reimbursed nationwide by health insurances...
Predictivity of thyroid autoantibodies for the development of thyroid disorders in children and adolescents with Type 1 diabetesO Kordonouri
Clinics for General Paediatrics and Paediatric Radiology, Otto Heubner Centre, Charite, Campus Virchow Klinikum, Humboldt University, Berlin, Germany
Diabet Med 19:518-21. 2002..To investigate the prevalence of thyroid autoantibodies and their significance for the development of thyroid disorders in children and adolescents with Type 1 diabetes...
Age-specific levels of diabetes-related GAD and IA-2 antibodies in healthy children and adultsOlga Kordonouri
Children s Hospital, Otto Heubner Centrum, Charite, Humboldt University, Berlin, Germany
J Pediatr Endocrinol Metab 15:47-52. 2002..027 (at least one antibody elevated). These data emphasize the importance of establishing age-specific reference values for DM-related antibodies in the background population before applying them for screening and intervention studies...
Prevalence of 20S proteasome, anti-nuclear and thyroid antibodies in young patients at onset of type 1 diabetes mellitus and the risk of autoimmune thyroiditisOlga Kordonouri
Clinics of General Pediatrics, Otto Heubner Centrum für Kinder und Jugendmedizin Charité, Berlin, Germany
J Pediatr Endocrinol Metab 17:975-81. 2004..In particular, patients with positive thyroid and anti-nuclear antibodies are at high risk to develop autoimmune thyroiditis during the first 5 years of DM1...
Identification of urinary protein pattern in type 1 diabetic adolescents with early diabetic nephropathy by a novel combined proteome analysisMatthias Meier
Department of Nephrology, Hannover Medical School, Carl Neuberg Strasse 1, Hannover D 30625, Germany
J Diabetes Complications 19:223-32. 2005..Future prospective studies with the application of this technique may enable the earlier and more accurate detection of individuals at high risk to develop diabetic nephropathy...
Continuing stability of center differences in pediatric diabetes care: do advances in diabetes treatment improve outcome? The Hvidoere Study Group on Childhood DiabetesCarine E de Beaufort
DECCP, Clinique Pédiatrique Centre Hospitalier, Luxembourg
Diabetes Care 30:2245-50. 2007....
The global burden of youth diabetes: perspectives and potentialHenk-Jan Aanstoot
DIABETER, Centre for Pediatric and Adolescent Diabetes Care and Research, Rotterdam, The Netherlands
Pediatr Diabetes 8:1-44. 2007
Insulin injection regimens and metabolic control in an international survey of adolescents with type 1 diabetes over 3 years: results from the Hvidore study groupReinhard W Holl
University of Ulm, ZIBMT, Albert Einstein Allee 47, 89081 Ulm, Germany
Eur J Pediatr 162:22-9. 2003..Conclusive evidence, however, should be based on prospectively planned, randomised therapeutic trials in paediatric patients...
[Type 1 and type 2 diabetes mellitus in Germany. An epidemic in all age groups]Thomas Danne
MMW Fortschr Med 146:27. 2004
Premixed biphasic insulin analogs - a choice for pediatric patients with type 2 diabetes rather than type 1 diabetes?Thomas Danne
Pediatr Diabetes 7:1-3. 2006
Use of insulin pump therapy in the pediatric age-group: consensus statement from the European Society for Paediatric Endocrinology, the Lawson Wilkins Pediatric Endocrine Society, and the International Society for Pediatric and Adolescent Diabetes, endorsMoshe Phillip
Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, Israel
Diabetes Care 30:1653-62. 2007
Glimepiride versus metformin as monotherapy in pediatric patients with type 2 diabetes: a randomized, single-blind comparative studyMichael Gottschalk
University of California, San Diego Medical Center, San Diego, CA 92123, USA
Diabetes Care 30:790-4. 2007..To compare the efficacy and safety of glimepiride versus metformin in pediatric subjects with type 2 diabetes inadequately controlled with diet and exercise alone or oral monotherapy...
Insulin pumps in pediatrics: we have the technology. We have the evidence. Why are still so few kids using it?Thomas Danne
Pediatr Diabetes 7:2-3. 2006
Risk of celiac disease in children with type 1 diabetes is modified by positivity for HLA-DQB1*02-DQA1*05 and TNF -308AZdenek Sumnik
Motol University Hospital, Charles University Prague, V Uvalu 84, CZ 150 06, Prague, The Czech Republic
Diabetes Care 29:858-63. 2006....
Parent and health professional perspectives in the management of adolescents with diabetes: development of assessment instruments for international studiesHilary Hoey
Department of Paediatrics, Trinity College, National Children s Hospital, Tallaght, Dublin, 24, Ireland
Qual Life Res 15:1033-42. 2006..Assessment of quality of life (QOL) in adolescents with diabetes requires patient, parent and health professional input. Psychometrically robust instruments to assess parent and professional perspectives are required...
Relation of circulating concentrations of chemokine receptor CCR5 ligands to C-peptide, proinsulin and HbA1c and disease progression in type 1 diabetesC Pfleger
Institute for Clinical Diabetes Research at German Diabetes Centre, Leibniz Institute at Heinrich Heine University Duesseldorf, Auf m Hennekamp 65, 40225 Duesseldorf, Germany
Clin Immunol 128:57-65. 2008..Blockage of chemokines or antagonism of CCR5 by therapeutic agents such as maraviroc may provide a new therapeutic target to ameliorate disease progression in type 1 diabetes...
