Arnd Kieser

Summary

Country: Germany

Publications

  1. doi request reprint The Latent Membrane Protein 1 (LMP1)
    Arnd Kieser
    Helmholtz Center Munich German Research Center for Environmental Health, Munich, Germany
    Curr Top Microbiol Immunol 391:119-49. 2015
  2. pmc The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor
    Anna Shkoda
    Research Unit Gene Vectors, Helmholtz Zentrum Munchen German Research Center for Environmental Health, Munchen, Germany
    PLoS Biol 10:e1001376. 2012
  3. pmc A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release
    Daniel Sauter
    Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany
    Retrovirology 10:85. 2013
  4. pmc Global gene expression changes of in vitro stimulated human transformed germinal centre B cells as surrogate for oncogenic pathway activation in individual aggressive B cell lymphomas
    Alexandra Schrader
    Department of Haematology and Oncology, University Medical Centre Göttingen, Gottingen, Germany
    Cell Commun Signal 10:43. 2012
  5. pmc Signal transduction, receptors, mediators and genes: younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology
    Frank Entschladen
    Institute of Immunology, Witten Herdecke University, Germany
    Cell Commun Signal 8:2. 2010
  6. pmc Signal transduction in the footsteps of goethe and schiller
    Karlheinz Friedrich
    Institute of Biochemistry, University of Jena Medical School, Jena, Germany
    Cell Commun Signal 7:2. 2009
  7. doi request reprint Pursuing different 'TRADDes': TRADD signaling induced by TNF-receptor 1 and the Epstein-Barr virus oncoprotein LMP1
    Arnd Kieser
    Abteilung Genvektoren, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt, Marchioninistrasse 25, D 81377 Munchen, Germany
    Biol Chem 389:1261-71. 2008
  8. pmc The viral oncoprotein LMP1 exploits TRADD for signaling by masking its apoptotic activity
    Frank Schneider
    Department of Gene Vectors, GSF National Research Center for Environment and Health, Munich, Germany
    PLoS Biol 6:e8. 2008
  9. ncbi request reprint The c-Jun N-terminal kinase pathway is critical for cell transformation by the latent membrane protein 1 of Epstein-Barr virus
    Helmut Kutz
    GSF National Research Center for Environment and Health, Department of Gene Vectors, Marchioninistrasse 25, D 81377 Munich, Germany
    Virology 371:246-56. 2008

Collaborators

  • Frank Entschladen
  • Karlheinz Friedrich
  • Helmut Kutz
  • Daniel Sauter
  • Fabian Giehler
  • Alexandra Schrader
  • Anna Shkoda
  • Janine Griese
  • Ralf Hass
  • Klaudia Giehl
  • Ottmar Janssen
  • Frank Schneider
  • Christian Kubisch
  • Frank Kirchhoff
  • Susanne Engelhart
  • Dominik Hotter
  • Martina Vockerodt
  • Hakan Sarioglu
  • Jennifer A Town
  • Elisabeth Hand
  • Michael Engelke
  • Dido Lenze
  • Dieter Kube
  • Lorenz Trumper
  • Frederike von Bonin
  • Kamila Matulewicz
  • Neele Walther
  • Antje Ulrich
  • Thomas Knöfel
  • Michael Hummel
  • Michael Romio
  • Katharina Meyer
  • Katharina F Kubatzky
  • Heike Hermanns
  • Ria Baumgrass
  • Lars Oliver Klotz
  • Joachim Altschmied
  • Otmar Huber
  • Iris Behrmann
  • Edgar Serfling
  • Jonathan A Lindquist
  • Christina Ehrhardt
  • Oliver Ullrich
  • Gerald Thiel
  • Stephan M Feller
  • Fred Schaper
  • Nicola Liefold
  • Julia Neugebauer
  • Gilbert Reisbach
  • Cinthia Briseño
  • Ute Schultheiss

Detail Information

Publications9

  1. doi request reprint The Latent Membrane Protein 1 (LMP1)
    Arnd Kieser
    Helmholtz Center Munich German Research Center for Environmental Health, Munich, Germany
    Curr Top Microbiol Immunol 391:119-49. 2015
    ..Here, we review LMP1's molecular and biological functions, highlighting the interface between LMP1 and the cellular signal transduction network as an important factor of virus-host interaction and a potential therapeutic target. ..
  2. pmc The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor
    Anna Shkoda
    Research Unit Gene Vectors, Helmholtz Zentrum Munchen German Research Center for Environmental Health, Munchen, Germany
    PLoS Biol 10:e1001376. 2012
    ..Our data establish TNIK as a novel key player in TRAF6-dependent JNK and NF-κB signaling and a transducer of activating and transforming signals in human B-cells...
  3. pmc A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release
    Daniel Sauter
    Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany
    Retrovirology 10:85. 2013
    ..However, non-synonymous polymorphisms in the bst2 open reading frame have not yet been described or functionally characterized...
  4. pmc Global gene expression changes of in vitro stimulated human transformed germinal centre B cells as surrogate for oncogenic pathway activation in individual aggressive B cell lymphomas
    Alexandra Schrader
    Department of Haematology and Oncology, University Medical Centre Göttingen, Gottingen, Germany
    Cell Commun Signal 10:43. 2012
    ..abstract:..
  5. pmc Signal transduction, receptors, mediators and genes: younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology
    Frank Entschladen
    Institute of Immunology, Witten Herdecke University, Germany
    Cell Commun Signal 8:2. 2010
    ..This report gives an overview of the presentations of the conference...
  6. pmc Signal transduction in the footsteps of goethe and schiller
    Karlheinz Friedrich
    Institute of Biochemistry, University of Jena Medical School, Jena, Germany
    Cell Commun Signal 7:2. 2009
    ..This report is intended to share with the readers of CCS some highlights of the Meeting Workshops devoted to specific aspects of signal transduction...
  7. doi request reprint Pursuing different 'TRADDes': TRADD signaling induced by TNF-receptor 1 and the Epstein-Barr virus oncoprotein LMP1
    Arnd Kieser
    Abteilung Genvektoren, Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt, Marchioninistrasse 25, D 81377 Munchen, Germany
    Biol Chem 389:1261-71. 2008
    ..This article provides an overview of TNFR1 and LMP1 signal transduction with a focus on TRADD's functions in apoptotic and transforming signaling, incorporating recent results from TRADD RNAi and knockout studies...
  8. pmc The viral oncoprotein LMP1 exploits TRADD for signaling by masking its apoptotic activity
    Frank Schneider
    Department of Gene Vectors, GSF National Research Center for Environment and Health, Munich, Germany
    PLoS Biol 6:e8. 2008
    ..Thus, the unique interaction of LMP1 with TRADD encodes the transforming phenotype of viral TRADD signaling and masks TRADD's pro-apoptotic function...
  9. ncbi request reprint The c-Jun N-terminal kinase pathway is critical for cell transformation by the latent membrane protein 1 of Epstein-Barr virus
    Helmut Kutz
    GSF National Research Center for Environment and Health, Department of Gene Vectors, Marchioninistrasse 25, D 81377 Munich, Germany
    Virology 371:246-56. 2008
    ..Our data support a critical role of the LMP1-induced JNK pathway for proliferation of LMP1-transformed cells and characterize JNK as a potential target for intervention against EBV-induced malignancies...