Nickias Kienle

Summary

Country: Germany

Publications

  1. pmc Phylogeny of the SNARE vesicle fusion machinery yields insights into the conservation of the secretory pathway in fungi
    Nickias Kienle
    Department of Neurobiology, Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    BMC Evol Biol 9:19. 2009
  2. doi request reprint Differences in the SNARE evolution of fungi and metazoa
    Nickias Kienle
    Structural Biochemistry Research Group, Department of Neurobiology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany
    Biochem Soc Trans 37:787-91. 2009
  3. pmc A coiled coil trigger site is essential for rapid binding of synaptobrevin to the SNARE acceptor complex
    Katrin Wiederhold
    Research Group Structural Biochemistry, Max Planck Institute for Biophysical Chemistry, 37077 Gottingen, Germany
    J Biol Chem 285:21549-59. 2010

Collaborators

Detail Information

Publications3

  1. pmc Phylogeny of the SNARE vesicle fusion machinery yields insights into the conservation of the secretory pathway in fungi
    Nickias Kienle
    Department of Neurobiology, Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    BMC Evol Biol 9:19. 2009
    ..Over the past 30 years, the yeast Saccharomyces cerevisiae has served as a powerful model organism for studying the organization of the secretory and endocytic pathways, and a few years ago, its entire set of SNAREs was compiled...
  2. doi request reprint Differences in the SNARE evolution of fungi and metazoa
    Nickias Kienle
    Structural Biochemistry Research Group, Department of Neurobiology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany
    Biochem Soc Trans 37:787-91. 2009
    ..The structural and functional diversity that exists between fungi and metazoa might offer a simple explanation for the distinct evolutionary history of their SNARE repertoires...
  3. pmc A coiled coil trigger site is essential for rapid binding of synaptobrevin to the SNARE acceptor complex
    Katrin Wiederhold
    Research Group Structural Biochemistry, Max Planck Institute for Biophysical Chemistry, 37077 Gottingen, Germany
    J Biol Chem 285:21549-59. 2010
    ..Moreover, the point mutations severely inhibited secretion from chromaffin cells. Altogether, this demonstrates that the trigger site in synaptobrevin is crucial for productive SNARE zippering...