Research Topics
| C KellinghausSummaryCountry: Germany Publications
| Collaborators
|
Detail Information
Publications
[Electric brain stimulation for epilepsy therapy]C Kellinghaus
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Nervenarzt 74:664-76. 2003..g., fornix, corpus callosum) as a new methodology to increase the efficacy of DBS ("overdrive method")...- Neurosarcoidosis: clinical experience and diagnostic pitfallsC Kellinghaus
Department of Neurology, University Hospital Munster, Albert Schweitzer Strasse 33, DE 48129 Münster, Germany
Eur Neurol 51:84-8. 2004..To describe a group of patients with neurosarcoidosis and to highlight diagnostic difficulties based on current diagnostic criteria... - Lateralizing value of Todd's palsy in patients with epilepsyChristoph Kellinghaus
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH, USA
Neurology 62:289-91. 2004..In the remaining two patients, the seizure onset could not be lateralized. In some patients, TP occurred after a seizure without focal motor features or secondary generalization... - Neurophysiological abnormalities in HIV-infected long term survivorsChristoph Kellinghaus
Department of Neurology, University of Munster, Albert Schweitzer Str 33, D 48129 Munster, Germany
Eur J Med Res 11:245-9. 2006..We investigated the prevalence and severity of neurophysiological abnormalities in LTS... - [Suggestion for a new, patient-oriented epilepsy classification]C Kellinghaus
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH, USA
Nervenarzt 77:961-9. 2006..Information from clinical tests such as MRI and EEG are translated into the best possible working hypothesis at the time of classification, allowing increased precision of the classification as additional information becomes available... - Dissociation between in vitro and in vivo epileptogenicity in a rat model of cortical dysplasiaChristoph Kellinghaus
Department of Neurology, The Cleveland Clinic Foundation, Ohio, USA
Epileptic Disord 9:11-9. 2007..The freeze-lesion model in rats shows histopathological features similar to those found in human polymicrogyria. Previous studies reported in vitro hyperexcitability in this model, but in vivo epileptogenicity has not been confirmed... - Tiagabine-related non-convulsive status epilepticus in partial epilepsy: three case reports and a review of the literatureChristoph Kellinghaus
Department of Neurology, University of Munster, Albert Schweitzer Strasse 33, 48129 Munster, Germany
Seizure 11:243-9. 2002..We review the other cases reported so far and discuss the different pathophysiological hypotheses about the association in the light of new experimental data... - Non-epileptic seizures of the elderlyChristoph Kellinghaus
Department of Neurology, The Cleveland Clinic Foundation, Ohio, USA
J Neurol 251:704-9. 2004..To characterize non-epileptic seizures (NES) in the elderly and compare their features with NES of a younger control group... - Seizure semiology in the elderly: a video analysisChristoph Kellinghaus
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Epilepsia 45:263-7. 2004..To describe the seizure semiology of patients older than 60 years and to compare it with that of a control group of younger adults matched according to the epilepsy diagnosis... - Frequency of seizures and epilepsy in neurological HIV-infected patientsC Kellinghaus
Department of Neurology, University Hospital Munster, Munster, Germany
Seizure 17:27-33. 2008..In addition, we compared the characteristics of patients who experienced provoked seizures only with those of patients who developed epilepsy... 
Localising and lateralising value of ictal piloerectionT Loddenkemper
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH 44195 5245, USA
J Neurol Neurosurg Psychiatry 75:879-83. 2004..One case series concluded that there is a predominant left hemispheric representation of ictal cold. The aim of this study is to evaluate the localising and lateralising value of pilomotor seizures...
Misdiagnosis of epileptic and non-epileptic seizures in a neurological intensive care unitF Boesebeck
University of Muenster, Department of Neurology, Muenster, Germany
Acta Neurol Scand 122:189-95. 2010..The etiological misinterpretation of paroxysmal neurological symptoms frequently causes a delayed treatment or an inappropriate utilization of ICU-capacities...- Temporal hypometabolism at the onset of cryptogenic temporal lobe epilepsyP Matheja
Department of Nuclear Medicine, Munster University, Germany
Eur J Nucl Med 28:625-32. 2001..The metabolic disturbance correlates with the number of seizures. These findings suggest that an initial dysfunction is present in a considerable number of patients and that hypometabolism is worsened by continuing epileptic activity... - Disturbed benzodiazepine receptor function at the onset of temporal lobe epilepsy--lomanzenil-binding in de-novo TLEP Matheja
Klinik und Poliklinik fur Nuklearmedizin, WWU Muenster, Germany
J Neurol 248:585-91. 2001..The aim of our study was to investigate the incidence of focal reductions of temporal benzodiazepine receptor binding (BRB) as assessed by scintigraphy with 123I-iomazenil in patients with denovo temporal lobe epilepsy (TLE)... - Are epilepsy classifications based on epileptic syndromes and seizure types outdated?H O Lüders
Epilepsy Center, Cleveland Clinic Foundation, Cleveland, OH, USA
Epileptic Disord 8:81-5. 2006 - Nerve fiber impairment of anterior thalamocortical circuitry in juvenile myoclonic epilepsyM Deppe
Department of Neurology, University of Muenster, Albert Schweitzer Str 33, 48129 Muenster, Germany
Neurology 71:1981-5. 2008..Juvenile myoclonic epilepsy (JME) is a syndrome of idiopathic generalized epilepsy (IGE) without structural brain abnormalities detectable by MRI or CT... - Intravenous lacosamide for treatment of status epilepticusC Kellinghaus
Department of Neurology, Klinikum Osnabruck, Germany
Acta Neurol Scand 123:137-41. 2011..Currently used first-line drugs may cause potentially hazardous side effects. We aimed to assess the efficacy and safety of intravenous lacosamide (LCM) in SE after failure of standard treatment... - Incidence of seizures in patients with multiple sclerosis treated with intrathecal baclofenS U Schuele
Department of Neurology S91, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Neurology 64:1086-7. 2005..05). Three patients with MS on ITB developed status epilepticus. Seizures were often associated with additional triggering factors... - Unilateral absence of the basal ganglia plus epilepsy without motor symptomsC Kellinghaus
Department of Neurology, The Cleveland Clinic Foundation, OH, USA
Neurology 60:870-3. 2003..Preserved motor function could be explained by neuronal plasticity involving contralateral corticostriatal and pallidothalamic connections and points to a lesion received in early pregnancy... - Nonconvulsion status epilepticus in patients with juvenile myoclonic epilepsy: types and frequenciesRainer Dziewas
Department of Neurology, University Clinic Münster, Albert Schweitzer Strasse 33, Munster, Germany
Seizure 11:335-9. 2002..According to our findings the prevalence of NCSE in JME can be estimated at 5.8%, the incidence at 1.2% per year with a clear preponderance of female gender... - Ictal spitting: clinical and electroencephalographic featuresChristoph Kellinghaus
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Epilepsia 44:1064-9. 2003..To identify clinical and EEG correlates of ictal spitting automatisms and to assess their reliability in indicating the hemisphere of seizure onset... - Specific epileptic syndromes are rare even in tertiary epilepsy centers: a patient-oriented approach to epilepsy classificationChristoph Kellinghaus
Department of Neurology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Epilepsia 45:268-75. 2004..In contrast, all of the patients could be classified by the five-dimensional patient-oriented classification, providing all essential information for the management of the patients with a high degree of interrater reliability... - Severity of histopathologic abnormalities and in vivo epileptogenicity in the in utero radiation model of rats is dose dependentChristoph Kellinghaus
Section of Epilepsy, Department of Neurology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Epilepsia 45:583-91. 2004..CONCLUSIONS: In vivo epileptogenicity in radiated animals was present only in mild or moderate MCD. No in vivo epileptogenicity was seen in severe radiation-induced MCD... - Focal semiologic and electroencephalographic features in patients with juvenile myoclonic epilepsyNaotaka Usui
Sections of Pediatric and Adult Epilepsy, Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Epilepsia 46:1668-76. 2005..CONCLUSIONS: Fourteen (54%) of 26 patients with JME exhibited focal semiologic or electroencephalographic features or both. Video-EEG was essential in reaching a correct diagnosis and choosing an appropriate antiepileptic drug regimen... - Frontal lobe epilepsyChristoph Kellinghaus
Dept. of Neurology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Epileptic Disord 6:223-39. 2004..Patients with frontal lobe epilepsy who do not respond to anticonvulsive medication, and who are not eligible for epilepsy surgery may benefit from alternative approaches such as electrical brain stimulation... - The prognostic value of [F]FDG-PET in nonrefractory partial epilepsyLars Weitemeyer
Department of Neurology, , , Germany
Epilepsia 46:1654-60. 2005..However, if PET data are available, they could help in identifying patients with a less benign course... - Electro-clinical and imaging characteristics of focal cortical dysplasia: correlation with pathological subtypesPeter Widdess-Walsh
Section of Epilepsy, Department of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, S51, Cleveland, OH 44195, USA
Epilepsy Res 67:25-33. 2005..CONCLUSIONS: Clinically important differences exist between the pathological subtypes of CD, which may assist in their management, and provide further insight into their underlying pathophysiology... - A proposal for a five-dimensional patient-oriented epilepsy classificationTobias Loddenkemper
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Epileptic Disord 7:308-16. 2005.... - Acute repetitive pilomotor seizuresChristoph Kellinghaus
Clin Neurophysiol 116:989-90; author reply 990. 2005 - Effects of subthalamic nucleus (STN) stimulation on motor cortex excitabilityTobias Loddenkemper
Neurology 60:885-6; author reply 885-6. 2003 - Repeated intracarotid amobarbital testsTobias Loddenkemper
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Epilepsia 48:553-8. 2007..Our goal was to determine the frequency of repeated intracarotid amobarbital test (IAT) at our center and to estimate the retest reliability of the IAT for both language and memory lateralization... - Epileptic monocular nystagmusChristoph Kellinghaus
Neurology 61:145-7; author reply 147. 2003 - Double-blind, randomized controlled study of bilateral cerebellar stimulationChristoph Kellinghaus
Epilepsia 47:1247; author reply 1248-9. 2006 - The NMDA receptor NR2B subunit contributes to epileptogenesis in human cortical dysplasiaGabriel Moddel
Department of Neurology, The Cleveland Clinic Foundation, OH 44195, USA
Brain Res 1046:10-23. 2005..NR2B may constitute a target for new diagnostic and pharmacotherapeutic approaches... - Pregabalin-associated acute psychosis and epileptiform EEG-changesItziar Olaizola
Department of Neurology, , Albert-Schweitzer-Street 33, , Germany
Seizure 15:208-10. 2006..We present a patient who, after unintended rapid up-titration of pregabalin, experienced psychotic symptoms associated with rhythmic EEG-changes resolving completely after discontinuation of pregabalin and benzodiazepine administration... - Effects of eyelid closure, blinks, and eye movements on the electroencephalogramMasaki Iwasaki
Department of Neurology, Cleveland Clinic Foundation, 9500 Euclid Avenue/Desk S90, Cleveland, OH 44195, USA
Clin Neurophysiol 116:878-85. 2005..SIGNIFICANCE: Care is required in attributing EEG artifacts to movements of either eyeball or eyelid, since our findings suggest that they both contribute to these potentials...