Ulrike Kammerer

Summary

Country: Germany

Publications

  1. doi request reprint Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK
    Melanie Schmidt
    Department of Gynaecology and Obstetrics, University of Wuerzburg, Josef Schneider Strasse 4, Wuerzburg, 97080, Germany
    J Cancer Res Clin Oncol 136:219-25. 2010
  2. pmc Increased tartrate-resistant acid phosphatase (TRAP) expression in malignant breast, ovarian and melanoma tissue: an investigational study
    A Honig
    Dept of Obstetrics and Gynecology, University of Wuerzburg, Germany
    BMC Cancer 6:199. 2006
  3. ncbi request reprint A new rapid immunohistochemical staining technique using the EnVision antibody complex
    U Kammerer
    Department of Obstetrics and Gynecology, University of Wuerzburg, Josef Schneider Str 4, D 97080 Wuerzburg, Germany
    J Histochem Cytochem 49:623-30. 2001
  4. ncbi request reprint Antigen-presenting cells in the decidua
    Ulrike Kammerer
    Department of Obstetrics and Gynecology, University of Wurzburg, Wurzburg, Germany
    Chem Immunol Allergy 89:96-104. 2005
  5. pmc Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial
    Melanie Schmidt
    Dept, Obstetrics and Gynecology, University Hospital of Wuerzburg, Josef Schneider Str, 4, D 97080 Wuerzburg, Germany
    Nutr Metab (Lond) 8:54. 2011
  6. ncbi request reprint Expression of tumor markers on breast and ovarian cancer cell lines
    Ulrike Kammerer
    Department of Obstetrics and Gynecology, University of Wuerzburg, Germany
    Anticancer Res 23:1051-5. 2003
  7. ncbi request reprint Immunocompetent cells in the endometrium of fetuses and children
    U Kammerer
    Department of Obstetrics and Gynaecology, University of Wurzburg, Josef Schneider Strasse 4, D 97080 Wurzburg, Germany
    Hum Reprod 18:969-75. 2003
  8. pmc Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy
    Ulrike Kammerer
    Department of Obstetrics and Gynecology, the University Medical School Würzburg, Wurzburg, Germany
    Am J Pathol 162:887-96. 2003
  9. ncbi request reprint Indoleamine 2,3-dioxygenase (IDO) expression in invasive extravillous trophoblast supports role of the enzyme for materno-fetal tolerance
    Arnd Honig
    Department of Obstetrics and Gynaecology, University of Wuerzburg, Josef Schneider Str 4, D 97080 Wuerzburg, Germany
    J Reprod Immunol 61:79-86. 2004
  10. ncbi request reprint The clinicopathological and prognostic relevance of pyruvate kinase M2 and pAkt expression in breast cancer
    Carina Benesch
    Department of Gynaecology and Obstetrics, University of Wuerzburg, Wuerzburg, Germany
    Anticancer Res 30:1689-94. 2010

Collaborators

Detail Information

Publications43

  1. doi request reprint Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK
    Melanie Schmidt
    Department of Gynaecology and Obstetrics, University of Wuerzburg, Josef Schneider Strasse 4, Wuerzburg, 97080, Germany
    J Cancer Res Clin Oncol 136:219-25. 2010
    ..To date, however, little is known about glucose metabolism in breast cancer tissue...
  2. pmc Increased tartrate-resistant acid phosphatase (TRAP) expression in malignant breast, ovarian and melanoma tissue: an investigational study
    A Honig
    Dept of Obstetrics and Gynecology, University of Wuerzburg, Germany
    BMC Cancer 6:199. 2006
    ..To elucidate this phenomenon, we examined the expression of TRAP in breast cancer cells and the cells of several other malignancies...
  3. ncbi request reprint A new rapid immunohistochemical staining technique using the EnVision antibody complex
    U Kammerer
    Department of Obstetrics and Gynecology, University of Wuerzburg, Josef Schneider Str 4, D 97080 Wuerzburg, Germany
    J Histochem Cytochem 49:623-30. 2001
    ..This method could be a useful new tool in frozen section diagnosis and research. (J Histochem Cytochem 49:623-630, 2001)..
  4. ncbi request reprint Antigen-presenting cells in the decidua
    Ulrike Kammerer
    Department of Obstetrics and Gynecology, University of Wurzburg, Wurzburg, Germany
    Chem Immunol Allergy 89:96-104. 2005
    ..This chapter summarizes the characteristics of dendritic cells and macrophages as APC in general and focuses on the description and characterization of APC in the decidua of different species found in the literature...
  5. pmc Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial
    Melanie Schmidt
    Dept, Obstetrics and Gynecology, University Hospital of Wuerzburg, Josef Schneider Str, 4, D 97080 Wuerzburg, Germany
    Nutr Metab (Lond) 8:54. 2011
    ..abstract:..
  6. ncbi request reprint Expression of tumor markers on breast and ovarian cancer cell lines
    Ulrike Kammerer
    Department of Obstetrics and Gynecology, University of Wuerzburg, Germany
    Anticancer Res 23:1051-5. 2003
    ..Breast and ovarian tumor cell lines with defined tumor-associated antigens could serve as allogeneic antigen-sources for the biological therapy of cancer...
  7. ncbi request reprint Immunocompetent cells in the endometrium of fetuses and children
    U Kammerer
    Department of Obstetrics and Gynaecology, University of Wurzburg, Josef Schneider Strasse 4, D 97080 Wurzburg, Germany
    Hum Reprod 18:969-75. 2003
    ..This study was undertaken to investigate the distribution of leukocyte subpopulations in the endometrium of fetuses and children...
  8. pmc Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy
    Ulrike Kammerer
    Department of Obstetrics and Gynecology, the University Medical School Würzburg, Wurzburg, Germany
    Am J Pathol 162:887-96. 2003
    ....
  9. ncbi request reprint Indoleamine 2,3-dioxygenase (IDO) expression in invasive extravillous trophoblast supports role of the enzyme for materno-fetal tolerance
    Arnd Honig
    Department of Obstetrics and Gynaecology, University of Wuerzburg, Josef Schneider Str 4, D 97080 Wuerzburg, Germany
    J Reprod Immunol 61:79-86. 2004
    ..Since EVT are the fetal cells with the closest contact to the maternal immune system, our results suggest that it is EVT which protects the fetus from rejection by downregulating local maternal T-cell responses...
  10. ncbi request reprint The clinicopathological and prognostic relevance of pyruvate kinase M2 and pAkt expression in breast cancer
    Carina Benesch
    Department of Gynaecology and Obstetrics, University of Wuerzburg, Wuerzburg, Germany
    Anticancer Res 30:1689-94. 2010
    ..Cancer cell growth has been described to depend on glucose utilization. Activation of Akt and up-regulation of pyruvate kinase M2 (M2-PK) are attributes of tumour glycolysis...
  11. ncbi request reprint RAF expression in human astrocytic tumors
    Carsten Hagemann
    Department of Neurosurgery, Tumorbiology Laboratory, University of Wurzburg, D 97080 Wurzburg, Germany
    Int J Mol Med 23:17-31. 2009
    ..Our data indicate that RAF proteins might be valuable targets for small molecule therapies. However, initially specific functions of RAF during tumorigenesis have to be elucidated...
  12. doi request reprint Impact of female sex hormones on the maturation and function of human dendritic cells
    Sabine E Segerer
    Department of Obstetrics and Gynaecology, University of Wurzburg, Wurzburg, Germany
    Am J Reprod Immunol 62:165-73. 2009
    ....
  13. ncbi request reprint Immunohistochemistry in human placental tissue--pitfalls of antigen detection
    Arnd Honig
    Department of Obstetrics and Gynecology, Josef Schneider Strasse 4, D 97080 Wurzburg, Germany
    J Histochem Cytochem 53:1413-20. 2005
    ..This blocking procedure could also be appropriate for frozen tissues other than placenta in which Fc receptors are expressed...
  14. pmc Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinoma
    Thomas G P Grunewald
    Institute of Clinical Biochemistry and Pathobiochemistry, University of Wuerzburg, Grombuehlstr, 12, D 97080 Wuerzburg, Germany
    BMC Cancer 7:198. 2007
    ....
  15. doi request reprint Upregulation of chemokine and cytokine production during pregnancy
    Sabine Segerer
    Department of Obstetrics and Gynecology, University of Wurzburg, Wurzburg, Germany
    Gynecol Obstet Invest 67:145-50. 2009
    ..In this study, we therefore compared chemokine and cytokine expression in the first- and third-trimester nonpregnant endometrium and decidua...
  16. doi request reprint Glucose metabolism and angiogenesis in granulosa cell tumors of the ovary: activation of Akt, expression of M2PK, TKTL1 and VEGF
    Melanie Schmidt
    Department of Gynaecology and Obstetrics, University of Wurzburg, Josef Schneider Strasse 4, 97080 Wurzburg, Germany
    Eur J Obstet Gynecol Reprod Biol 139:72-8. 2008
    ..Thus, we focussed on a selection of key factors in angiogenesis and tumor glycolysis to study metabolic characteristics of granulosa cell tumors of the ovary...
  17. ncbi request reprint Pregnancy associated hormones modulate the cytokine production but not the phenotype of PBMC-derived human dendritic cells
    Barbara Huck
    Department of Gynaecology and Obstetrics, University of Wurzburg, Josef Schneider Str 4, D 97080, Wurzburg, Germany
    Eur J Obstet Gynecol Reprod Biol 122:85-94. 2005
    ..As effects of pregnancy associated hormones on phenotype and function of DC are unknown, our objective was to test the influence of progesterone, beta-estradiol and betaHCG on immature (iDC) and mature (mDC) DC...
  18. pmc Specific subsets of immune cells in human decidua differ between normal pregnancy and preeclampsia--a prospective observational study
    Lorenz Rieger
    Department of Obstetrics and Gynaecology, University of Wurzburg, Josef Schneider Str, 4, D 97080 Wurzburg, Germany
    Reprod Biol Endocrinol 7:132. 2009
    ..In this study, we therefore investigated the leucocyte subpopulations in decidual tissues of 33 women with preeclampsia and 66 control patients...
  19. doi request reprint Human decidua and invasive trophoblasts are rich sources of nearly all human matrix metalloproteinases
    Jelena Anacker
    Department of Obstetrics and Gynaecology, University Hospital of Wurzburg, Germany
    Mol Hum Reprod 17:637-52. 2011
    ..It can be speculated that expression of MMPs correlates with the invasive potential of CTBs together with a crucial role in activation of labour at term...
  20. pmc The glycoprotein-hormones activin A and inhibin A interfere with dendritic cell maturation
    Sabine E Segerer
    University of Wurzburg, Department of Obstetrics and Gynecology, Josef Schneider Strasse 4, 97080 Wurzburg, Germany
    Reprod Biol Endocrinol 6:17. 2008
    ....
  21. ncbi request reprint Expression of the NKG2D ligand UL16 binding protein-1 (ULBP-1) on dendritic cells
    David Schrama
    Department of Dermatology, Julius Maximilians University, Wurzburg, Germany
    Eur J Immunol 36:65-72. 2006
    ..Thus, our results suggest a role for NGK2D-ULBP-1 in the induction or reactivation of T cell responses...
  22. ncbi request reprint Expression analysis of the autosomal recessive primary microcephaly genes MCPH1 (microcephalin) and MCPH5 (ASPM, abnormal spindle-like, microcephaly associated) in human malignant gliomas
    Carsten Hagemann
    Department of Neurosurgery, University of Wurzburg, D 97080 Wurzburg, Germany
    Oncol Rep 20:301-8. 2008
    ..Our findings are significant as the expression of ASPM may be used as a marker for glioma malignancy and represents a potential therapeutic target...
  23. ncbi request reprint The expression of galectin-1 in vulvar neoplasia
    Nico Kohrenhagen
    Department of Obstetrics and Gynaecology, University Hospital, University of Wuerzburg, Wuerzburg, Germany
    Anticancer Res 30:1547-52. 2010
    ....
  24. doi request reprint Antigen-presenting cells in pregnant and non-pregnant human myometrium
    Marina Ivanisevic
    Department of Obstetrics and Gynecology, Julius Maximilians Universitat Wurzburg, Wurzburg, Germany
    Am J Reprod Immunol 64:188-96. 2010
    ..Numerous studies have described the decidual immune cell population in pregnant and non-pregnant endometrium. However, little is known about the presence of immune cells in human myometrium...
  25. pmc Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature
    Andrea Köhrmann
    Department of Obstetrics and Gynecology, University of Wurzburg, Wurzburg, Germany
    BMC Cancer 9:188. 2009
    ..This physiological balance seems to be disrupted in cancer making tumor cells capable of invading the tissue. In breast cancer different expression levels of several MMPs have been found...
  26. ncbi request reprint Expression of VEGFR-1 (Flt-1) in breast cancer is associated with VEGF expression and with node-negative tumour stage
    Melanie Schmidt
    Department of Gynaecology and Obstetrics, University of Wuerzburg, Germany
    Anticancer Res 28:1719-24. 2008
    ..The impact of autocrine signalling loops on treatment with VEGF inhibitors is still unclear...
  27. ncbi request reprint Role of dendritic cells in the regulation of maternal immune responses to the fetus during mammalian gestation
    Ulrike Kammerer
    Department of Obstetrics and Gynecology, University of Wurzburg, Wurzburg, Germany
    Immunol Invest 37:499-533. 2008
    ....
  28. ncbi request reprint Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia
    Nico Kohrenhagen
    Departments of Obstetrics and Gynecology, University of Wuerzburg, Wuerzburg, Germany
    J Obstet Gynaecol Res 34:293-300. 2008
    ..Transketolase-like enzyme 1 (TKTL1) and the oncogene p-Akt have been described to play an important role in glycolysis during tumorigenesis. Thus, we were interested in their expression in cervical tissue...
  29. pmc Expression pattern of matrix metalloproteinases in human gynecological cancer cell lines
    Andrea Schröpfer
    Department of Obstetrics and Gynecology, University of Wuerzburg, Josef Schneider Str 4, 97080 Wuerzburg, Germany
    BMC Cancer 10:553. 2010
    ..g. endometrial, cervical or ovarian carcinoma). In this study we investigated the expression pattern of the 23 MMPs, currently known in humans, in different gynecological cancer cell lines...
  30. ncbi request reprint Production of IL-12 and IL-18 in human dendritic cells upon infection by Listeria monocytogenes
    Annette Kolb-Mäurer
    Department of Dermatology, University of Wurzburg, 97080 Wurzburg, Germany
    FEMS Immunol Med Microbiol 35:255-62. 2003
    ..The release of both stimulating cytokines IL-12 and IL-18 upon infection with entire bacteria suggests that attenuated strains of L. monocytogenes may be a valuable tool for subunit vaccine delivery...
  31. doi request reprint Quantification of the predominant immune cell populations in decidua throughout human pregnancy
    Catharina Bartmann
    Department of Obstetrics and Gynecology, University Hospital of Wurzburg, Wurzburg, Germany
    Am J Reprod Immunol 71:109-19. 2014
    ..In this study, we therefore analyzed the proportion of the dominant decidual leukocytes in human tissue samples derived from all phases of pregnancy...
  32. ncbi request reprint Profiling chemokines, cytokines and growth factors in human early pregnancy decidua by protein array
    Sabine Engert
    Department of Obstetrics and Gynaecology, University of Wurzburg, Wurzburg, Germany
    Am J Reprod Immunol 58:129-37. 2007
    ..Cytokines and chemokines have been suggested as key factors for the regulation of these complex cellular migration and interaction processes...
  33. ncbi request reprint Respiratory response of malignant and placental cells to changes in oxygen concentration
    Assegid Garedew
    Department of Obstetrics and Gynaecology, University of Wurzburg, Germany
    Respir Physiol Neurobiol 165:154-60. 2009
    ..The JO2 of foetal leucocytes and malignant cells responded to the change in [O2] in a similar manner, and may indicate comparable mechanisms of adaptation to hypoxia...
  34. ncbi request reprint Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas
    Hans Ullrich Völker
    Insitute of Pathology, University of Wurzburg, Josef Schneider Str 2, 97080, Wurzburg, Germany
    Eur Arch Otorhinolaryngol 264:1431-6. 2007
    ..TKTL1 overexpression is associated with a more aggressive behavior and shorter survival of laryngeal SCCs. These observations could lead to additional therapeutic options targeting a blocking of the enzyme activity...
  35. pmc Expression of p-AKT characterizes adenoid cystic carcinomas of head and neck with a higher risk for tumor relapses
    Hans Ullrich Völker
    Institute for Pathology, University Wurzburg, Wurzburg, Germany
    Diagn Pathol 4:18. 2009
    ..The identification of tumors with a higher relapse risk seems to be interesting. Hence we investigated parameters of glucose metabolism, which were found associated with poor prognosis in other malignancies...
  36. ncbi request reprint Anatomic location and T-cell stimulatory functions of mouse dendritic cell subsets defined by CD4 and CD8 expression
    Alexander D McLellan
    Department of Dermatology, University of Wurzburg, Joseph Schneider Strasse 2, Wurzburg 97080, Germany
    Blood 99:2084-93. 2002
    ..Thus, the inability of CD8alpha+ DCs to stimulate CD8+ T cells is limited to certain in vitro assays that must lack certain enhancing signals present during in vivo interaction between CD8alpha+ DCs and CD8+ T cells...
  37. doi request reprint Seminal plasma protects human spermatozoa and pathogenic yeasts from capture by dendritic cells
    Claudia Rennemeier
    Department of Obstetrics and Gynecology, University of Wurzburg, Wurzburg, Germany
    Hum Reprod 26:987-99. 2011
    ..In the present study, we investigated the potential interaction of spermatozoa with DCs and raised the question of whether seminal plasma impacts the interaction of DCs with spermatozoa or pathogenic microbes...
  38. pmc Expression-analysis of the human endogenous retrovirus HERV-K in human astrocytic tumors
    Almuth Friederike Kessler
    Tumorbiology Laboratory, Department of Neurosurgery, University of Wurzburg, Josef Schneider Str, 11, Würzburg D 97080, Germany
    BMC Res Notes 7:159. 2014
    ..Patients have a limited prognosis of 14.6 months in median, despite standard treatment. Therefore, we elucidated whether HERV-K transcripts could be detected in these tumors and serve as new molecular target for treatment...
  39. ncbi request reprint Characterization of an intramolecular protein-protein interaction in c-Ets1 and its viral homologue v-Ets
    Melanie Schmidt
    Department of Gynaecology and Obstetrics, University of Wurzburg, 97080 Wurzburg, Germany
    Oncol Rep 18:457-63. 2007
    ..In v-Ets in which the C-terminal domain is mutated this interaction appears to lead to strong DNA binding affinity. Therefore, changes in v-Ets might contribute to the tumorigenic process by altering intramolecular interactions...
  40. ncbi request reprint Tubal abortions but not viable tubal pregnancies are characterized by an increased number of CD8+ T cells
    Birgit Kemp
    Department of Obstetrics and Gynecology, Medical School, RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Germany
    J Reprod Immunol 73:180-7. 2007
    ..To examine immune cell phenotypes in viable tubal pregnancies (VTP) and in tubal abortions (TA)...
  41. ncbi request reprint Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells
    Thomas G P Grunewald
    Institute of Clinical Biochemistry and Pathobiochemistry, University of Wurzburg, Grombühlstr 12, D 97080 Wurzburg, Germany
    Exp Cell Res 312:974-82. 2006
    ..The data provide evidence for an essential role of LASP-1 in tumor cell growth and migration, possibly by influencing the localization of zyxin...
  42. ncbi request reprint Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas
    Hans Ullrich Völker
    Institute of Pathology, Julius Maximillians University, Wurzburg, Germany
    Am J Clin Pathol 130:50-7. 2008
    ..The percentage of positive cells for TKTL1 and p-Akt was significantly correlated. These observations could lead to additional therapeutic options targeting a specific blockade of TKTL1 enzyme activity...
  43. pmc Natural resistance to ascorbic acid induced oxidative stress is mainly mediated by catalase activity in human cancer cells and catalase-silencing sensitizes to oxidative stress
    Christoph Klingelhoeffer
    Experimental Surgery, Department of Surgery, University of Wurzburg Hospital, Germany
    BMC Complement Altern Med 12:61. 2012
    ..The purpose of this study was to analyse the impact of catalase, an important hydrogen peroxide-detoxifying enzyme, on the resistance of cancer cells to ascorbic acid mediated oxidative stress...