Frank J Kaiser

Summary

Country: Germany

Publications

  1. ncbi SUMOylation modulates transcriptional repression by TRPS1
    Frank J Kaiser
    Institut fur Humangenetik, Universitatsklinikum Essen, D 45122 Essen, Germany
    Biol Chem 388:381-90. 2007
  2. ncbi The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor
    Frank J Kaiser
    Institut fur Humangenetik, Universitatsklinikum, Hufelandstrasse 55, D 45122 Essen, Germany
    J Biol Chem 278:38780-5. 2003
  3. ncbi Nuclear interaction of the dynein light chain LC8a with the TRPS1 transcription factor suppresses the transcriptional repression activity of TRPS1
    Frank J Kaiser
    Institut fur Humangenetik, Universitatsklinikum, Hufelandstr 55, D 45122 Essen, Germany
    Hum Mol Genet 12:1349-58. 2003
  4. ncbi The Cohesin loading factor NIPBL recruits histone deacetylases to mediate local chromatin modifications
    Philipp Jahnke
    Institut fur Humangenetik, Universitat zu Lubeck, 23538 Lubeck, Germany
    Nucleic Acids Res 36:6450-8. 2008
  5. ncbi Novel missense mutations in the TRPS1 transcription factor define the nuclear localization signal
    Frank J Kaiser
    , , Hufelandstr 55, Essen D-45122, Germany
    Eur J Hum Genet 12:121-6. 2004
  6. ncbi Synergistic cooperation of Sall4 and Cyclin D1 in transcriptional repression
    Johann Böhm
    Institut fur Humangenetik und Anthropologie, Universitat Freiburg, Freiburg, Germany
    Biochem Biophys Res Commun 356:773-9. 2007

Collaborators

Detail Information

Publications6

  1. ncbi SUMOylation modulates transcriptional repression by TRPS1
    Frank J Kaiser
    Institut fur Humangenetik, Universitatsklinikum Essen, D 45122 Essen, Germany
    Biol Chem 388:381-90. 2007
    ..These results identify SUMOylation at the TRPS1-RD as a major mechanism that regulates the function of TRPS1...
  2. ncbi The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor
    Frank J Kaiser
    Institut fur Humangenetik, Universitatsklinikum, Hufelandstrasse 55, D 45122 Essen, Germany
    J Biol Chem 278:38780-5. 2003
    ..Using a luciferase reporter assay, we could demonstrate that the repressional function of TRPS1 is inhibited by RNF4. This finding suggests that RNF4 is a negative regulator of TRPS1 activity...
  3. ncbi Nuclear interaction of the dynein light chain LC8a with the TRPS1 transcription factor suppresses the transcriptional repression activity of TRPS1
    Frank J Kaiser
    Institut fur Humangenetik, Universitatsklinikum, Hufelandstr 55, D 45122 Essen, Germany
    Hum Mol Genet 12:1349-58. 2003
    ..In addition, GATA-regulated reporter gene assay indicated that LC8a is able to suppress the transcriptional repression activity of TRPS1...
  4. ncbi The Cohesin loading factor NIPBL recruits histone deacetylases to mediate local chromatin modifications
    Philipp Jahnke
    Institut fur Humangenetik, Universitat zu Lubeck, 23538 Lubeck, Germany
    Nucleic Acids Res 36:6450-8. 2008
    ..Our data are the first to indicate a molecular and functional connection of NIPBL with chromatin-remodeling processes via the direct interaction with histone deacetylases...
  5. ncbi Novel missense mutations in the TRPS1 transcription factor define the nuclear localization signal
    Frank J Kaiser
    , , Hufelandstr 55, Essen D-45122, Germany
    Eur J Hum Genet 12:121-6. 2004
    ..In contrast, a mutant that lacks the conserved GATA-type zinc-finger domain and most of the LRRRRG motif is able to enter the nucleus...
  6. ncbi Synergistic cooperation of Sall4 and Cyclin D1 in transcriptional repression
    Johann Böhm
    Institut fur Humangenetik und Anthropologie, Universitat Freiburg, Freiburg, Germany
    Biochem Biophys Res Commun 356:773-9. 2007
    ..Furthermore, using luciferase reporter gene assays we demonstrate that Sall4 operates as a transcriptional repressor located to heterochromatin and that this activity is modulated by Cyclin D1...