Jens Wagenblast

Summary

Affiliation: Johann Wolfgang Goethe University
Country: Germany

Publications

  1. ncbi request reprint HPV status and overall survival of patients with oropharyngeal squamous cell carcinoma--a retrospective study of a German head and neck cancer center
    Aykut Tahtali
    ENT Department, University Hospital, Theodor Stern Kai 7, 60590 Frankfurt Main, Germany
    Anticancer Res 33:3481-5. 2013
  2. ncbi request reprint Does dexamethasone inhibit anticancer activity of cetuximab in squamous cell carcinoma cell lines of the head and neck?
    Jens Wagenblast
    ENT Department, Goethe University Medical School, Frankfurt am Main, Germany
    Oncol Rep 22:171-6. 2009
  3. ncbi request reprint AdOnco database - six years' experience with the documentation of clinical and scientific data on patients with head and neck cancer
    Jens Wagenblast
    ENT Department, Goethe University Medical School, Frankfurt am Main, Germany
    In Vivo 24:603-6. 2010
  4. ncbi request reprint Does dexamethasone inhibit the antineoplastic effect of cisplatin and docetaxel in head and neck cancer cells?
    Jens Wagenblast
    ENT Department, University Hospital, Theodor Stern Kai 7, 60590 Frankfurt Main, Germany
    Anticancer Res 30:123-7. 2010
  5. ncbi request reprint Effects of combination treatment of bortezomib and dexamethasone in SCCHN cell lines depend on tumor cell specificity
    Jens Wagenblast
    ENT Department, Goethe University Medical School, Frankfurt am Main, Germany
    Oncol Rep 20:1207-11. 2008
  6. doi request reprint Cetuximab enhances the efficacy of bortezomib in squamous cell carcinoma cell lines
    Jens Wagenblast
    ENT Department, Frankfurt University Medical School, University Hospital, Theodor Stern Kai 7, 60590, Frankfurt Main, Germany
    J Cancer Res Clin Oncol 135:387-93. 2009
  7. ncbi request reprint Craniofacial reconstructions with bone-anchored epithesis in head and neck cancer patients--a valid way back to self-perception and social reintegration
    Jens Wagenblast
    Department of ENT Surgery, Medical School, Goethe University, 60590 Frankfurt am Main, Germany
    Anticancer Res 28:2349-52. 2008
  8. ncbi request reprint Effect of bortezomib and cetuximab in EGF-stimulated HNSCC
    Jens Wagenblast
    ENT Department, Medical School, Goethe University, 60590 Frankfurt am Main, Germany
    Anticancer Res 28:2239-43. 2008
  9. ncbi request reprint Antiproliferative activity of bortezomib alone and in combination with cisplatin or docetaxel in head and neck squamous cell carcinoma cell lines
    Jens Wagenblast
    ENT Department, Medical School, Goethe University, Frankfurt am Main, Germany
    J Cancer Res Clin Oncol 134:323-30. 2008
  10. ncbi request reprint Water swallow screening test for patients after surgery for head and neck cancer: early identification of dysphagia, aspiration and limitations of oral intake
    Christiane Hey
    Department of Phoniatrics and Pediatric Audiology, University of Frankfurt Main, Theodor Stern Kai 7, house 7A, D 60590 Frankfurt Main, Germany
    Anticancer Res 33:4017-21. 2013

Collaborators

Detail Information

Publications28

  1. ncbi request reprint HPV status and overall survival of patients with oropharyngeal squamous cell carcinoma--a retrospective study of a German head and neck cancer center
    Aykut Tahtali
    ENT Department, University Hospital, Theodor Stern Kai 7, 60590 Frankfurt Main, Germany
    Anticancer Res 33:3481-5. 2013
    ..The aim of this study was to determine the HPV status in all OSCC specimens collected in our biological database since 1988, correlating the results with overall survival, and to compare them with the current literature data...
  2. ncbi request reprint Does dexamethasone inhibit anticancer activity of cetuximab in squamous cell carcinoma cell lines of the head and neck?
    Jens Wagenblast
    ENT Department, Goethe University Medical School, Frankfurt am Main, Germany
    Oncol Rep 22:171-6. 2009
    ..Thus, further studies are required to elucidate the molecular mechanisms underlying the interaction between dexamethasone and cetuximab in different tumors...
  3. ncbi request reprint AdOnco database - six years' experience with the documentation of clinical and scientific data on patients with head and neck cancer
    Jens Wagenblast
    ENT Department, Goethe University Medical School, Frankfurt am Main, Germany
    In Vivo 24:603-6. 2010
    ..To report the experience with AdOnco, a computerized database for head and neck cancer patients...
  4. ncbi request reprint Does dexamethasone inhibit the antineoplastic effect of cisplatin and docetaxel in head and neck cancer cells?
    Jens Wagenblast
    ENT Department, University Hospital, Theodor Stern Kai 7, 60590 Frankfurt Main, Germany
    Anticancer Res 30:123-7. 2010
    ..The present study was the first to investigate the effect of dexamethasone on the antiproliferative activity of cisplatin and docetaxel in vitro in squamous cell carcinoma of the head and neck (SCCHN) cell lines...
  5. ncbi request reprint Effects of combination treatment of bortezomib and dexamethasone in SCCHN cell lines depend on tumor cell specificity
    Jens Wagenblast
    ENT Department, Goethe University Medical School, Frankfurt am Main, Germany
    Oncol Rep 20:1207-11. 2008
    ..Therefore, further studies will be required to elucidate these molecular factors to substantiate our findings from a cancer biological point of view...
  6. doi request reprint Cetuximab enhances the efficacy of bortezomib in squamous cell carcinoma cell lines
    Jens Wagenblast
    ENT Department, Frankfurt University Medical School, University Hospital, Theodor Stern Kai 7, 60590, Frankfurt Main, Germany
    J Cancer Res Clin Oncol 135:387-93. 2009
    ..In this in vitro study, we investigated the antitumor effect of bortezomib (Velcade) in combination with cetuximab in squamous cell carcinoma cell lines (SCC)...
  7. ncbi request reprint Craniofacial reconstructions with bone-anchored epithesis in head and neck cancer patients--a valid way back to self-perception and social reintegration
    Jens Wagenblast
    Department of ENT Surgery, Medical School, Goethe University, 60590 Frankfurt am Main, Germany
    Anticancer Res 28:2349-52. 2008
    ....
  8. ncbi request reprint Effect of bortezomib and cetuximab in EGF-stimulated HNSCC
    Jens Wagenblast
    ENT Department, Medical School, Goethe University, 60590 Frankfurt am Main, Germany
    Anticancer Res 28:2239-43. 2008
    ..In this in vitro study, the antitumor effect of bortezomib (Velcade) in combination with cetuximab was investigated in epidermal growth factor (EGF)-stimulated head and neck squamous cell carcinoma cell lines (HNSCC)...
  9. ncbi request reprint Antiproliferative activity of bortezomib alone and in combination with cisplatin or docetaxel in head and neck squamous cell carcinoma cell lines
    Jens Wagenblast
    ENT Department, Medical School, Goethe University, Frankfurt am Main, Germany
    J Cancer Res Clin Oncol 134:323-30. 2008
    ....
  10. ncbi request reprint Water swallow screening test for patients after surgery for head and neck cancer: early identification of dysphagia, aspiration and limitations of oral intake
    Christiane Hey
    Department of Phoniatrics and Pediatric Audiology, University of Frankfurt Main, Theodor Stern Kai 7, house 7A, D 60590 Frankfurt Main, Germany
    Anticancer Res 33:4017-21. 2013
    ..6; limitations of oral intake=3.1). However, it is an accurate tool for the early identification of OD in general, with a sensitivity of 96.2% and a positive likelihood ratio of 5.4 in patients after surgery for HNC. ..
  11. pmc The role of recombinant epidermal growth factor and serotonin in the stimulation of tumor growth in a SCCHN xenograft model
    Christin Geissler
    ENT Department, Medical School, Goethe University, Frankfurt am Main, Germany
    Oncol Rep 28:785-90. 2012
    ..In our future investigations, we plan to include a higher number of mice, an adjustment of the EGF dosage and cell subanalysis, considering the heterogeneity of SCCHN tumors...
  12. ncbi request reprint Effect of bortezomib on EGFR expression in head and neck squamous cell carcinoma cell lines
    Jens Wagenblast
    ENT Department, Medical School, Goethe University, 60590 Frankfurt am Main, Germany
    Anticancer Res 28:687-92. 2008
    ..The present study investigated whether bortezomib has an effect on EGFR expression in different squamous cell carcinoma cell lines...
  13. ncbi request reprint The role of p16 expression as a predictive marker in HPV-positive oral SCCHN--a retrospective single-center study
    Christin Geißler
    ENT Department, University Hospital, Theodor Stern Kai 7, 60590 Frankfurt Main, Germany
    Anticancer Res 33:913-6. 2013
    ..The aim of the present study was to determine the role of p16 expression as a predictive marker of HPV infection in SCCHN tumors in a retrospective single-center study...
  14. ncbi request reprint Iron oxide particle-enhanced magnetic resonance imaging for detection of benign lymph nodes in the head and neck: how reliable are the results?
    Mehran Baghi
    Department of ENT Surgery, J W Goethe University, School of Medicine, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
    Anticancer Res 27:3571-5. 2007
    ..To evaluate the accuracy of ultrasmall paramagnetic iron oxide (USPIO: Sinerem)-enhanced MRI in patients with head and neck cancer and enlarged lymph nodes compared with current staging examinations using histology as a gold standard...
  15. ncbi request reprint Usefulness of MRI volumetric evaluation in patients with squamous cell cancer of the head and neck treated with neoadjuvant chemotherapy
    Mehran Baghi
    Department for ENT Surgery, University of Frankfurt Main, Theodor Stern Kai, 60590 Frankfurt am Main, Germany
    Head Neck 29:104-8. 2007
    ..The purpose was to evaluate the efficacy of tumor volumetry on MRI as predictive of response to treatment with induction chemotherapy, comparing the results with endoscopy...
  16. ncbi request reprint Inverse correlation between serum PGE2 and T classification in head and neck cancer
    Markus Hambek
    ENT Department, Johann Wolfgang Goethe Universitat Frankfurt Main, Theodor Stern Kai 7, Frankfurt 60590, Germany
    Head Neck 29:244-8. 2007
    ..We hypothesized that PGE2 is strictly required for aggressive and especially early-stage tumors of the head and neck to provoke invasion and angiogenesis...
  17. ncbi request reprint Heterogeneity of primary site biopsies in head and neck squamous cell carcinoma
    Susanne Moertel
    Department of Otorhinolaryngology, JW Goethe University, Theodor Stern Kai 7, 60590 Frankfurt Main, Germany
    Anticancer Res 31:665-9. 2011
    ..In our study, the impact of two different biopsy methods on the results of immunohistochemical staining of the samples for epidermal growth factor receptor (EGFR) and the proliferation antigen Ki-67 were evaluated...
  18. ncbi request reprint The challenge of tumor heterogeneity--different phenotypes of cancer stem cells in a head and neck squamous cell carcinoma xenograft mouse model
    Christin Geißler
    ENT Department, Medical School, Goethe University, and University Hospital, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
    In Vivo 26:593-8. 2012
    ..The aim of the present study was to illuminate the role and behaviour of (CD44) and (ALDH1A1) as tumor stem cell markers in a xenograft mouse model of squamous cell carcinoma...
  19. pmc Spiral ganglion stem cells can be propagated and differentiated into neurons and glia
    Marc Diensthuber
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Frankfurt am Main, Goethe University, Frankfurt am Main, Germany Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts
    Biores Open Access 3:88-97. 2014
    ..Thus, our work provides further evidence that self-renewing spiral ganglion stem cells might serve as a promising source for the regeneration of lost auditory neurons...
  20. doi request reprint Reirradiation with cetuximab in locoregional recurrent and inoperable squamous cell carcinoma of the head and neck: feasibility and first efficacy results
    Panagiotis Balermpas
    Department of Radiation Therapy and Oncology, Goethe University, Frankfurt am Main, Germany
    Int J Radiat Oncol Biol Phys 83:e377-83. 2012
    ..To report our experience with a prospective protocol of external beam reirradiation (Re-RT) combined with cetuximab for patients with inoperable, recurrent squamous cell carcinoma of the head and neck (SCCHN)...
  21. ncbi request reprint Predictability of oral and laryngopharyngeal function for aspiration and limitation of oral intake in patients after surgery for head and neck cancer
    Christiane Hey
    Department of Phoniatrics and Pediatric Audiology, University of Frankfurt Main, Theodor Stern Kai 7, house 7A, D 60590 Frankfurt Main, Germany
    Anticancer Res 33:3347-53. 2013
    ..Clinical assessment is therefore inappropriate for early detection of swallowing disorders in such patients. ..
  22. doi request reprint A comparison of tumour perfusion assessed by deconvolution-based analysis of dynamic contrast-enhanced CT and MR imaging in patients with squamous cell carcinoma of the upper aerodigestive tract
    Sotirios Bisdas
    Department of Diagnostic and Interventional Radiology, Johann Wolfgang University Hospital, Theodor Stern Kai 7, 60590, Frankfurt, Germany
    Eur Radiol 18:843-50. 2008
    ....
  23. doi request reprint Re-irradiation with cetuximab or cisplatin-based chemotherapy for recurrent squamous cell carcinoma of the head and neck
    Nicolas Dornoff
    Department of Radiotherapy and Oncology, J W Goethe University, Theodor Stern Kai 7, 60590, Frankfurt a M, Germany
    Strahlenther Onkol 191:656-64. 2015
    ..We compared the efficacy and toxicity of either cisplatin or cetuximab in combination with re-irradiation (ReRT) for recurrent unresectable SCCHN. Various clinicopathological factors were investigated to establish a prognostic score...
  24. doi request reprint Clonal colony formation from spiral ganglion stem cells
    Marc Diensthuber
    aDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Frankfurt am Main, Goethe University, Frankfurt M, bInstitute of Veterinary Anatomy, Histology, and Embryology, Justus Liebig University Giessen, Giessen, Germany
    Neuroreport 25:1129-35. 2014
    ....
  25. ncbi request reprint A phase II trial of docetaxel, cisplatin and 5-fluorouracil in patients with recurrent squamous cell carcinoma of the head and neck (SCCHN)
    Mehran Baghi
    Department for ENT Surgery, University of Frankfurt am Main, Germany
    Anticancer Res 26:585-90. 2006
    ..In this phase II study, for the first time the efficacy and toxicity of triple chemotherapy with docetaxel, cisplatin and 5-fluorouracil (TPF) in patients with recurrent head and neck cancer was evaluated...
  26. doi request reprint Gadolinium-enhanced echo-planar T2-weighted MRI of tumors in the extracranial head and neck: feasibility study and preliminary results using a distributed-parameter tracer kinetic analysis
    Sotirios Bisdas
    Department of Diagnostic and Interventional Radiology, Johann Wolfgang Goethe University Hospital, Frankfurt, Germany
    J Magn Reson Imaging 27:963-9. 2008
    ..To examine the feasibility of first-pass dynamic contrast-enhanced (DCE) T2-weighted MRI of tumors in the extracranial head and neck by applying a distributed-parameter (DP) tracer kinetic model to quantify the perfusion parameters...
  27. ncbi request reprint Dynamic contrast-enhanced CT of head and neck tumors: perfusion measurements using a distributed-parameter tracer kinetic model. Initial results and comparison with deconvolution-based analysis
    Sotirios Bisdas
    Department of Diagnostic and Interventional Radiology, Johann Wolfgang Goethe University Hospital, 60590 Frankfurt, Germany
    Phys Med Biol 52:6181-96. 2007
    ....
  28. ncbi request reprint Demands on caring relatives of head and neck cancer patients
    Mehran Baghi
    Department of Otorhinolaryngology, School of Medicine, J W Goethe University, Frankfurt, Germany
    Laryngoscope 117:712-6. 2007
    ....