Joerg Trojan

Summary

Affiliation: Johann Wolfgang Goethe-University
Country: Germany

Publications

  1. ncbi request reprint Thymosin beta 4 expression and nuclear transport are regulated by hMLH1
    Angela Brieger
    Department of Internal Medicine I, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt a M, Germany
    Biochem Biophys Res Commun 364:731-6. 2007
  2. ncbi request reprint Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system
    Joerg Trojan
    Second Department of Medicine, Johann Wolfgang Goethe University, Frankfurt a M, Germany
    Gastroenterology 122:211-9. 2002
  3. doi request reprint Malignant fibrous histiocytoma is a rare Lynch syndrome-associated tumor in two German families
    Angela Brieger
    Medical Clinic 1, Biomedical Research Laboratory, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Fam Cancer 10:591-5. 2011
  4. ncbi request reprint Detection of microsatellite instability from archival, hematoxylin-eosin-stained colorectal cancer specimen
    Joerg Trojan
    Second Department of Internal Medicine, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Arch Pathol Lab Med 126:202-4. 2002
  5. ncbi request reprint BAX and caspase-5 frameshift mutations and spontaneous apoptosis in colorectal cancer with microsatellite instability
    Joerg Trojan
    2nd Department of Medicine and Senckenberg Center of Pathology, Johann Wolfgang Goethe University Medical Center, Theodor Stern Kai 7, 60590 Frankfurt a M, Germany
    Int J Colorectal Dis 19:538-44. 2004

Detail Information

Publications5

  1. ncbi request reprint Thymosin beta 4 expression and nuclear transport are regulated by hMLH1
    Angela Brieger
    Department of Internal Medicine I, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt a M, Germany
    Biochem Biophys Res Commun 364:731-6. 2007
    ..Moreover, loss of hMLH1 causes Tbeta4 deprivation and results in reduced migratory activity in vitro. These data give insight into novel functions of hMLH1 and probably disease related dysregulated mechanisms...
  2. ncbi request reprint Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system
    Joerg Trojan
    Second Department of Medicine, Johann Wolfgang Goethe University, Frankfurt a M, Germany
    Gastroenterology 122:211-9. 2002
    ..To date, functional analysis of missense mutations has been performed primarily in Saccharomyces cerevisiae. The aim of this study was to examine the biochemical properties of hMLH1 protein variants in a human expression system...
  3. doi request reprint Malignant fibrous histiocytoma is a rare Lynch syndrome-associated tumor in two German families
    Angela Brieger
    Medical Clinic 1, Biomedical Research Laboratory, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Fam Cancer 10:591-5. 2011
    ..In conclusion, our data further support that patients with Lynch syndrome are at increased risk for rare tumors such as MFH. However, the prognosis compared to sporadic MFH seems to be favorable...
  4. ncbi request reprint Detection of microsatellite instability from archival, hematoxylin-eosin-stained colorectal cancer specimen
    Joerg Trojan
    Second Department of Internal Medicine, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Arch Pathol Lab Med 126:202-4. 2002
    ..In conclusion, this study demonstrates the feasibility of MSI analysis by direct fluorescence polymerase chain reaction amplification using hematoxylin-eosin-stained tissue specimens without the need for prior DNA extraction...
  5. ncbi request reprint BAX and caspase-5 frameshift mutations and spontaneous apoptosis in colorectal cancer with microsatellite instability
    Joerg Trojan
    2nd Department of Medicine and Senckenberg Center of Pathology, Johann Wolfgang Goethe University Medical Center, Theodor Stern Kai 7, 60590 Frankfurt a M, Germany
    Int J Colorectal Dis 19:538-44. 2004
    ..The aim of this study was to further characterize the role of BAX and cas-5 inactivation for spontaneous apoptosis...