Patrick Meybohm

Summary

Affiliation: Johann Wolfgang Goethe University
Country: Germany

Publications

  1. ncbi request reprint Remote ischaemic preconditioning for heart surgery. The study design for a multi-center randomized double-blinded controlled clinical trial--the RIPHeart-Study
    Patrick Meybohm
    Clinic of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Theodor Stern Kai 7, Frankfurt am Main, Germany
    Eur Heart J 33:1423-6. 2012
  2. doi request reprint [Tools for junior scientists support from medical societies: survey amongst members organized in the Association of the Scientific Medical Societies (AWMF)]
    Patrick Meybohm
    Klinik fur Anasthesiologie, Intensivmedizin und Schmerztherapie, Universitatsklinikum Frankfurt, Frankfurt, Deutschland Electronic address
    Z Evid Fortbild Qual Gesundhwes 109:632-41. 2015
  3. doi request reprint [Patient blood management : Current state of the literature]
    P Meybohm
    Klinik fur Anasthesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Frankfurt am Main, Theodor Stern Kai 7, 60590, Frankfurt am Main, Deutschland
    Chirurg 87:40-6. 2016
  4. pmc Should we restrict erythrocyte transfusion in early goal directed protocols?
    Patrick Meybohm
    Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Theodor Stern Kai 7, 60590, Frankfurt am Main, Germany
    BMC Anesthesiol 15:75. 2015
  5. pmc Safety and effectiveness of a Patient Blood Management (PBM) program in surgical patients--the study design for a multi-centre prospective epidemiologic non-inferiority trial
    Patrick Meybohm
    Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Theodor Stern Kai 7, 60590, Frankfurt am Main, Germany
    BMC Health Serv Res 14:576. 2014
  6. pmc SodiUm SeleniTe Adminstration IN Cardiac Surgery (SUSTAIN CSX-trial): study design of an international multicenter randomized double-blinded controlled trial of high dose sodium-selenite administration in high-risk cardiac surgical patients
    Christian Stoppe
    Department of Anesthesiology, University Hospital of the RWTH Aachen, Pauwelsstrase 30, 52074 Aachen, Germany
    Trials 15:339. 2014
  7. pmc Activities of cardiac tissue matrix metalloproteinases 2 and 9 are reduced by remote ischemic preconditioning in cardiosurgical patients with cardiopulmonary bypass
    Karina Zitta
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig Holstein, Kiel, Germany
    J Transl Med 12:94. 2014
  8. pmc Postoperative neurocognitive dysfunction in patients undergoing cardiac surgery after remote ischemic preconditioning: a double-blind randomized controlled pilot study
    Patrick Meybohm
    Clinic of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
    PLoS ONE 8:e64743. 2013
  9. pmc Aprotinin may increase mortality in low and intermediate risk but not in high risk cardiac surgical patients compared to tranexamic acid and ε-aminocaproic acid -- a meta-analysis of randomised and observational trials of over 30.000 patients
    Patrick Meybohm
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
    PLoS ONE 8:e58009. 2013
  10. pmc Influence of hypothermia and subsequent rewarming upon leukocyte-endothelial interactions and expression of Junctional-Adhesion-Molecules A and B
    Nicolai V Bogert
    Department of Thoracic and Cardiovascular Surgery, University Hospital Frankfurt, Goethe University, Frankfurt Main, Germany
    Sci Rep 6:21996. 2016

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Remote ischaemic preconditioning for heart surgery. The study design for a multi-center randomized double-blinded controlled clinical trial--the RIPHeart-Study
    Patrick Meybohm
    Clinic of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Theodor Stern Kai 7, Frankfurt am Main, Germany
    Eur Heart J 33:1423-6. 2012
    ..The purpose of this report is to describe the design and methods used in the "Remote Ischaemic Preconditioning for Heart Surgery (RIPHeart)-Study"...
  2. doi request reprint [Tools for junior scientists support from medical societies: survey amongst members organized in the Association of the Scientific Medical Societies (AWMF)]
    Patrick Meybohm
    Klinik fur Anasthesiologie, Intensivmedizin und Schmerztherapie, Universitatsklinikum Frankfurt, Frankfurt, Deutschland Electronic address
    Z Evid Fortbild Qual Gesundhwes 109:632-41. 2015
    ..A systematic survey of existing support tools and their dissemination among the medical societies has not yet been conducted...
  3. doi request reprint [Patient blood management : Current state of the literature]
    P Meybohm
    Klinik fur Anasthesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Frankfurt am Main, Theodor Stern Kai 7, 60590, Frankfurt am Main, Deutschland
    Chirurg 87:40-6. 2016
    ..Due to these serious deficits in patient care, in 2011 the World Health Organization recommended the implementation of a patient blood management (PBM)...
  4. pmc Should we restrict erythrocyte transfusion in early goal directed protocols?
    Patrick Meybohm
    Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Theodor Stern Kai 7, 60590, Frankfurt am Main, Germany
    BMC Anesthesiol 15:75. 2015
    ..But more importantly, early goal-directed therapy also became standard care for non-septic critically ill patients and was adopted for high-risk surgical patients...
  5. pmc Safety and effectiveness of a Patient Blood Management (PBM) program in surgical patients--the study design for a multi-centre prospective epidemiologic non-inferiority trial
    Patrick Meybohm
    Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Theodor Stern Kai 7, 60590, Frankfurt am Main, Germany
    BMC Health Serv Res 14:576. 2014
    ..Patient Blood Management (PBM) concepts aim to increase and preserve autologous erythrocyte volume and to optimise haemotherapy. They thus have great potential to benefit patients...
  6. pmc SodiUm SeleniTe Adminstration IN Cardiac Surgery (SUSTAIN CSX-trial): study design of an international multicenter randomized double-blinded controlled trial of high dose sodium-selenite administration in high-risk cardiac surgical patients
    Christian Stoppe
    Department of Anesthesiology, University Hospital of the RWTH Aachen, Pauwelsstrase 30, 52074 Aachen, Germany
    Trials 15:339. 2014
    ..Thus, a large-scale study is needed to investigate the effect of perioperative selenium supplementation on the occurrence of postoperative organ dysfunction...
  7. pmc Activities of cardiac tissue matrix metalloproteinases 2 and 9 are reduced by remote ischemic preconditioning in cardiosurgical patients with cardiopulmonary bypass
    Karina Zitta
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig Holstein, Kiel, Germany
    J Transl Med 12:94. 2014
    ..Here we investigated the effects of RIPC on the activities of heart tissue MMP-2/9 and their correlation with serum concentrations of cardiac troponin T (cTnT), a marker for myocardial damage...
  8. pmc Postoperative neurocognitive dysfunction in patients undergoing cardiac surgery after remote ischemic preconditioning: a double-blind randomized controlled pilot study
    Patrick Meybohm
    Clinic of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
    PLoS ONE 8:e64743. 2013
    ..We hypothesized that RIPC reduces postoperative neurocognitive dysfunction (POCD) in patients undergoing complex cardiac surgery...
  9. pmc Aprotinin may increase mortality in low and intermediate risk but not in high risk cardiac surgical patients compared to tranexamic acid and ε-aminocaproic acid -- a meta-analysis of randomised and observational trials of over 30.000 patients
    Patrick Meybohm
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
    PLoS ONE 8:e58009. 2013
    ..To compare the effect of aprotinin with the effect of lysine analogues (tranexamic acid and ε-aminocaproic acid) on early mortality in three subgroups of patients: low, intermediate and high risk of cardiac surgery...
  10. pmc Influence of hypothermia and subsequent rewarming upon leukocyte-endothelial interactions and expression of Junctional-Adhesion-Molecules A and B
    Nicolai V Bogert
    Department of Thoracic and Cardiovascular Surgery, University Hospital Frankfurt, Goethe University, Frankfurt Main, Germany
    Sci Rep 6:21996. 2016
    ..Endothelial protection prior to warm reperfusion and mild hypothermic conditions reducing the difference between hypothermia and rewarming temperatures should be considered. ..
  11. doi request reprint Multiple electrode aggregometry for the assessment of acquired platelet dysfunctions during extracorporeal circulation
    Haitham Mutlak
    Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany
    Thorac Cardiovasc Surg 63:21-7. 2015
    ..The aim of the present investigation was to study the capability of the multiple electrode aggregometry (MEA) using the Multiplate (Roche AG, Grenzach, Germany) device to reflect the extent of ECC-associated platelet dysfunctions...
  12. doi request reprint [Hemorrhage after accidental overdosage of enoxaparin: monitoring and therapy]
    Christian Friedrich Weber
    Klinik fur Anasthesiologie, Intensivmedizin und Schmerztherapie, Universitatsklinikum Frankfurt, Frankfurt am Main
    Anasthesiol Intensivmed Notfallmed Schmerzther 49:368-73. 2014
    ..A few hours later an excessive coagulopathy developed and necessitated the transfusion of allogenic blood products. The present case report describes and discusses our diagnostic and therapeutic approaches...
  13. doi request reprint Novel method to leukoreduce murine blood for transfusion: how to reduce animal usage
    Dania Fischer
    Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt Main, Germany
    Transfusion 56:146-52. 2016
    ..The commonly used neonatal LR filter (LRF) is associated with considerable animal numbers. A more efficient method would help support the guiding principles of "replacement, reduction, refinement" (3Rs)...
  14. doi request reprint Contribution of Ninjurin1 to Toll-like receptor 4 signaling and systemic inflammation
    Carla Jennewein
    1 Department of Anesthesiology, Intensive Care Medicine, and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany and
    Am J Respir Cell Mol Biol 53:656-63. 2015
    ..Our data contribute to a better understanding of the complex inflammatory mechanisms and add a novel therapeutic target for inflammatory conditions such as sepsis. ..
  15. doi request reprint Patient blood management: is it worth to be employed?
    Suma Choorapoikayil
    Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
    Curr Opin Anaesthesiol 29:186-91. 2016
    ..This review will exemplify the need of patient centered treatments and highlight recent findings in the field of PBM...
  16. doi request reprint Methylene blue modulates adhesion molecule expression on microvascular endothelial cells
    Isabella Werner
    Department of Thoracic and Cardiovascular Surgery, University Hospital Frankfurt, Goethe University, Theodor Stern Kai 7, 60590, Frankfurt am Main, Germany
    Inflamm Res 63:649-56. 2014
    ....
  17. pmc Individual Organ Failure and Concomitant Risk of Mortality Differs According to the Type of Admission to ICU - A Retrospective Study of SOFA Score of 23,795 Patients
    Tobias M Bingold
    Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt am Main, Theodor Stern Kai 7, D 60590 Frankfurt am Main, Germany
    PLoS ONE 10:e0134329. 2015
    ....
  18. doi request reprint [Management of extended blood loss and massive transfusion]
    Christian F Weber
    Klinik fur Anasthesiologie, Intensivmedizin und Schmerztherapie, Universitatsklinikum Frankfurt
    Anasthesiol Intensivmed Notfallmed Schmerzther 48:314-7. 2013
    ..Our guideline may be used as a template for other institutions...