Nicole Forestier

Summary

Affiliation: Johann Wolfgang Goethe University
Country: Germany

Publications

  1. doi Treatment of chronic hepatitis C patients with the NS3/4A protease inhibitor danoprevir (ITMN-191/RG7227) leads to robust reductions in viral RNA: a phase 1b multiple ascending dose study
    Nicole Forestier
    J W Goethe Universitat, Frankfurt, Germany
    J Hepatol 54:1130-6. 2011
  2. doi Antiviral activity of danoprevir (ITMN-191/RG7227) in combination with pegylated interferon α-2a and ribavirin in patients with hepatitis C
    Nicole Forestier
    JW Goethe University Hospital, Frankfurt, Germany
    J Infect Dis 204:601-8. 2011
  3. pmc Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma
    Verena Bihrer
    Department of Medicine I, University of Frankfurt M, Frankfurt, Germany
    PLoS ONE 6:e26971. 2011
  4. ncbi Acoustic radiation force impulse imaging for evaluation of antiviral treatment response in chronic hepatitis C
    Nicole Forestier
    Department of Internal Medicine 1, Faculty of Medicine, J W Goethe University, Frankfurt, Germany
    J Gastrointestin Liver Dis 21:367-73. 2012
  5. doi Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection
    Verena Bihrer
    Department of Medicine I, University of Frankfurt M, Frankfurt, Germany
    Am J Gastroenterol 106:1663-9. 2011
  6. doi Novel hepatitis C drugs in current trials
    Bernd Kronenberger
    Zentrum der Inneren Medizin, Medizinische Klinik 1, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt, Germany
    Clin Liver Dis 12:529-55, viii. 2008

Detail Information

Publications6

  1. doi Treatment of chronic hepatitis C patients with the NS3/4A protease inhibitor danoprevir (ITMN-191/RG7227) leads to robust reductions in viral RNA: a phase 1b multiple ascending dose study
    Nicole Forestier
    J W Goethe Universitat, Frankfurt, Germany
    J Hepatol 54:1130-6. 2011
    ..The present study assessed the safety, pharmacokinetics, and antiviral activity of danoprevir in a randomized, placebo-controlled, 14-day multiple ascending dose study in patients with chronic HCV genotype 1 infection...
  2. doi Antiviral activity of danoprevir (ITMN-191/RG7227) in combination with pegylated interferon α-2a and ribavirin in patients with hepatitis C
    Nicole Forestier
    JW Goethe University Hospital, Frankfurt, Germany
    J Infect Dis 204:601-8. 2011
    ..Current therapy options for patients with chronic hepatitis C virus (HCV) infection genotype 1 are effective in <50%. Danoprevir (ITMN-191/RG7227) is a potent, selective, and orally active inhibitor of the HCV NS3/4A serine protease...
  3. pmc Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma
    Verena Bihrer
    Department of Medicine I, University of Frankfurt M, Frankfurt, Germany
    PLoS ONE 6:e26971. 2011
    ..Here we correlated serum miR-21 levels with clinical parameters in patients with different stages of chronic hepatitis C virus infection (CHC) and CHC-associated HCC...
  4. ncbi Acoustic radiation force impulse imaging for evaluation of antiviral treatment response in chronic hepatitis C
    Nicole Forestier
    Department of Internal Medicine 1, Faculty of Medicine, J W Goethe University, Frankfurt, Germany
    J Gastrointestin Liver Dis 21:367-73. 2012
    ..The aim of the present study was to demonstrate a significant difference of ARFI-values in patients with sustained-virological-response (SVR) as compared to patients without...
  5. doi Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection
    Verena Bihrer
    Department of Medicine I, University of Frankfurt M, Frankfurt, Germany
    Am J Gastroenterol 106:1663-9. 2011
    ..Here, we investigated if the serum levels of miR-122 might be useful as disease parameter in patients with chronic hepatitis C virus (HCV) infection...
  6. doi Novel hepatitis C drugs in current trials
    Bernd Kronenberger
    Zentrum der Inneren Medizin, Medizinische Klinik 1, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt, Germany
    Clin Liver Dis 12:529-55, viii. 2008
    ....