D Jocham

Summary

Country: Germany

Publications

  1. pmc Could titanium oxide coating from a sol-gel process make stone baskets more resistant to laser radiation at 2.1 μm?
    Jens Cordes
    Clinic of Urology, University of Lubeck, University Medical Center Schleswig Holstein, Ratzeburgerallee 160, D 23538, Lubeck, Germany
    J Negat Results Biomed 11:15. 2012
  2. doi request reprint [The care situation of patients with interstitial cystitis in Germany: results of a survey of 270 patients]
    D Jocham
    Urologische Klinik und Poliklinik, Universitat zu Lubeck, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Deutschland
    Urologe A 52:691-702. 2013
  3. ncbi request reprint Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: phase III, randomised controlled trial
    Dieter Jocham
    Department of Urology, University of Lubeck Medical School, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Lancet 363:594-9. 2004
  4. ncbi request reprint [Obstruction of the lower urinary tract]
    D Jocham
    Klinik und Poliklinik fur Urologie, Medizinische Universitat, Ratzeburger Allee 160, 23538 Lubeck
    Urologe A 41:342-5. 2002
  5. ncbi request reprint Photodynamic diagnosis in urology: state-of-the-art
    Dieter Jocham
    Department of Urology, University of Lubeck, Lubeck, Germany
    Eur Urol 53:1138-48. 2008
  6. doi request reprint [BCG versus photodynamic therapy (PDT) for nonmuscle invasive bladder cancer-a multicentre clinical phase III study]
    D Jocham
    Die Institutsangaben sind am Ende des Beitrags gelistet
    Aktuelle Urol 40:91-9. 2009
  7. doi request reprint [Squamous cell carcinoma of the renal pelvis. Therapeutic options for a rare entity]
    B Kazarians
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck
    Aktuelle Urol 39:456-8. 2008
  8. ncbi request reprint [Ki-67 antisense therapy in murine renal cell carcinoma models]
    I Kausch
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck
    Aktuelle Urol 36:142-8. 2005
  9. ncbi request reprint [Is there an indication for neoadjuvant or adjuvant systemic therapy in renal cell cancer?]
    C Doehn
    Klinik und Poliklinik fur Urologie, Universitätsklinikum Schleswig Holstein UK S H, Campus Lubeck, Ratzeburger Allee 160, 23538 Lubeck
    Urologe A 46:1371-2, 1374, 1376-8. 2007
  10. ncbi request reprint [Vaccine therapy of prostate cancer]
    C Doehn
    Klinik und Poliklinik fur Urologie, Universitätsklinikum Schleswig Holstein UKSH, Campus Lubeck
    Aktuelle Urol 36:407-16. 2005

Detail Information

Publications69

  1. pmc Could titanium oxide coating from a sol-gel process make stone baskets more resistant to laser radiation at 2.1 μm?
    Jens Cordes
    Clinic of Urology, University of Lubeck, University Medical Center Schleswig Holstein, Ratzeburgerallee 160, D 23538, Lubeck, Germany
    J Negat Results Biomed 11:15. 2012
    ..Stone baskets could be easily destroyed by Holmium:YAG-laser at an endourologic treatment, with respect to this, we try to improve the resistance by coating them with a titanium oxide layer. The layer was established by a sol-gel-process...
  2. doi request reprint [The care situation of patients with interstitial cystitis in Germany: results of a survey of 270 patients]
    D Jocham
    Urologische Klinik und Poliklinik, Universitat zu Lubeck, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Deutschland
    Urologe A 52:691-702. 2013
    ..Despite comprehensive literature on IC (62,000 citations in PubMed) almost nothing is known of the everyday care and quality of patient care in Germany...
  3. ncbi request reprint Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: phase III, randomised controlled trial
    Dieter Jocham
    Department of Urology, University of Lubeck Medical School, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Lancet 363:594-9. 2004
    ..At present, no effective adjuvant treatment is established. We aimed to investigate the effect of an autologous renal tumour cell vaccine on risk of tumour progression in patients with stage pT2-3b pN0-3 M0 renal-cell carcinoma...
  4. ncbi request reprint [Obstruction of the lower urinary tract]
    D Jocham
    Klinik und Poliklinik fur Urologie, Medizinische Universitat, Ratzeburger Allee 160, 23538 Lubeck
    Urologe A 41:342-5. 2002
    ..A proper patient selection for therapy and a mobilization of the symptomatic patient will also be important targets in the future...
  5. ncbi request reprint Photodynamic diagnosis in urology: state-of-the-art
    Dieter Jocham
    Department of Urology, University of Lubeck, Lubeck, Germany
    Eur Urol 53:1138-48. 2008
    ..To provide an overview on the methodology and clinical relevance of fluorescence diagnosis with exogenous fluorochromes or fluorochrome prodrugs in urology...
  6. doi request reprint [BCG versus photodynamic therapy (PDT) for nonmuscle invasive bladder cancer-a multicentre clinical phase III study]
    D Jocham
    Die Institutsangaben sind am Ende des Beitrags gelistet
    Aktuelle Urol 40:91-9. 2009
    ....
  7. doi request reprint [Squamous cell carcinoma of the renal pelvis. Therapeutic options for a rare entity]
    B Kazarians
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck
    Aktuelle Urol 39:456-8. 2008
    ..The patient with SCC described here showed an above-average survival of 18 months after adjuvant radiochemotherapy. Treatment was initiated according to the guidelines for squamous cell carcinoma in non-urological localisations...
  8. ncbi request reprint [Ki-67 antisense therapy in murine renal cell carcinoma models]
    I Kausch
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck
    Aktuelle Urol 36:142-8. 2005
    ..We intended to evaluate the effects of this therapeutic concept in two renal cell carcinoma (RCC) models...
  9. ncbi request reprint [Is there an indication for neoadjuvant or adjuvant systemic therapy in renal cell cancer?]
    C Doehn
    Klinik und Poliklinik fur Urologie, Universitätsklinikum Schleswig Holstein UK S H, Campus Lubeck, Ratzeburger Allee 160, 23538 Lubeck
    Urologe A 46:1371-2, 1374, 1376-8. 2007
    ..New trials are testing tyrosine kidney inhibitors such as sunitinib and sorafenib...
  10. ncbi request reprint [Vaccine therapy of prostate cancer]
    C Doehn
    Klinik und Poliklinik fur Urologie, Universitätsklinikum Schleswig Holstein UKSH, Campus Lubeck
    Aktuelle Urol 36:407-16. 2005
    ..Side effects of vaccination are generally mild. At present, there are trials are being planned or are already ongoing that combine vaccine with other treatment strategies or enroll patients with earlier disease stages...
  11. ncbi request reprint [Localized amyloidosis of the ureter]
    B Kazarians
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, Lubeck, Germany
    Urologe A 46:1718-20. 2007
    ..The patient was treated successfully by partial ureterectomy and ureteroneocystostomy. No systemic involvement of other organs was detected and after a 2-year follow-up no local recurrence developed...
  12. ncbi request reprint Inhibition of bcl-2 enhances the efficacy of chemotherapy in renal cell carcinoma
    I Kausch
    Department of Urology, University of Lubeck, Medical School, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Eur Urol 47:703-9. 2005
    ..However, no studies on the efficacy of this approach in RCC have been reported so far. This study aimed to evaluate whether bcl-2 asON could enhance efficacy of chemotherapy in human RCC...
  13. ncbi request reprint [Immunotherapy of renal cell carcinoma: results from current phase-III-trials]
    C Doehn
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck
    Aktuelle Urol 35:121-9. 2004
    ..This review presents the results from current phase-III-trials investigating immunotherapy for renal carcinoma...
  14. doi request reprint [Ureteropelvic junction obstruction with renal hypertension]
    B Kazarians
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck
    Aktuelle Urol 42:190-2. 2011
    ..We report a case of renal hypertension with ureteropelvic junction obstruction successfully corrected by laparoscopic pyeloplasty and discuss the pathophysiology...
  15. ncbi request reprint Reduction of side effects of intravesical therapy with bacille Calmette-Guérin by pentoxifylline?--an in vitro approach
    A Bohle
    Department of Urology, Medical University of Lubeck, Lubeck, Germany
    Clin Infect Dis 31:S101-5. 2000
    ..From these data, we conclude that the use of pentoxifylline to reduce BCG-related side effects should be tested further in a clinical study...
  16. ncbi request reprint Technology evaluation: TG-1031, Transgene SA
    C Doehn
    Department of Urology, Medical University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Curr Opin Mol Ther 2:106-11. 2000
    ..This therapy has potential for the treatment of breast cancer, prostate cancer and other adenocarcinomas and is currently under investigation in phase I and II trials...
  17. doi request reprint [Stromal tumour of uncertain malignant potential of the prostate (STUMP) - a case report]
    J M Laturnus
    Klinik und Poliklinik fur Urologie, Universitätsklinikum Schleswig Holstein UKSH, Campus Lubeck
    Aktuelle Urol 41:197-9. 2010
    ..The patient is being seen -frequently in our clinic to take prostate biopsies to exclude a progression into a stromal sarcoma (active surveillance). After 13 months the STUMP is still detectable, but with no signs of sarcoma...
  18. doi request reprint [Causes and course of fornix rupture]
    C Doehn
    Klinik und Poliklinik fur Urologie, Universitätsklinikum Schleswig Holstein UK S H, Campus Lubeck
    Aktuelle Urol 41:119-21. 2010
    ..Fornix rupture is a urological emergency situation. In most cases ureteral stones represent the underlying cause. We present the largest series ever reported...
  19. ncbi request reprint Laparoscopic nephroureterectomy to exclude upper urinary tract malignancy associated with analgesic nephropathy
    C Doehn
    Department of Urology, Medical University of Lubeck, Germany
    J Endourol 15:809-14. 2001
    ..All patients were scheduled to be put on the waiting list for cadaveric renal transplantation...
  20. ncbi request reprint Adjuvant autologous tumour cell-lysate vaccine versus no adjuvant treatment in patients with M0 renal cell carcinoma after radical nephrectomy: 3-year interim analysis of a German multicentre phase-III trial
    Ch Doehn
    Department of Urology, University of Lubeck Medical School, Lubeck, Germany
    Folia Biol (Praha) 49:69-73. 2003
    ..However, it must be emphasized that the results of the final study report (2003) must be awaited before definite recommendations can be made...
  21. ncbi request reprint Technology evaluation: CN-706, Calydon Inc
    C Doehn
    Department of Urology, Medical University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Curr Opin Mol Ther 2:703-8. 2000
    ..In June 1999, Calydon was issued two further patents [US-05871726], [US-05830686], [327511]...
  22. ncbi request reprint The fate of bacillus Calmette-Guerin after intravesical instillation
    C Durek
    Department of Urology, , National Reference Center for Mycobacteria, Germany
    J Urol 165:1765-8. 2001
    ..Long lasting and persistent BCG DNA in the bladder wall may account for long-term immuno-activation. However, the remaining BCG may be a possible source of late systemic infections...
  23. ncbi request reprint Ki-67-directed antisense therapy in an orthotopic renal cell carcinoma model
    I Kausch
    Department of Urology, University of Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Eur Urol 46:118-24; discussion 124-5. 2004
    ..Since ON are known to accumulate in vivo in the kidney, high local effectivity may be expected. Here, we evaluated and characterized antitumoral effects in an orthotopic renal cell cancer (RENCA) model...
  24. doi request reprint [Fluorescence diagnosis in patients with non-muscle invasive bladder cancer: results of a metaanalysis]
    I Kausch
    Klinik für Urologie, Universitat zu Lubeck, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Lubeck, Deutschland
    Aktuelle Urol 41:171-7. 2010
    ..Heterogeneous results of single studies with photodynamic diagnosis (PDD) in bladder cancer have been reported. A metaanalysis of prospective studies has now been performed...
  25. ncbi request reprint Vaccination immunotherapy--an update
    C Doehn
    Department of Urology, University of Lubeck Medical School, Lubeck, Germany
    Scand J Surg 93:163-9. 2004
    ..Ongoing efforts focus on development of more powerful vaccines. This review summarizes vaccination approaches for renal cell carcinomas published in the past 4 years...
  26. ncbi request reprint [Treatment of superficial bladder tumor]
    D Jocham
    Medizinische Universitat zu Lubeck, Klinik und Poliklinik fur Urologie, Ratzeburger Allee 160, 23538 Lubeck
    Urologe A 40:460-3. 2001
    ..Some treatment options, such as instillation of bacillus Calmette-Guérin, have been validated by large randomized studies in the sense of evidence-based medicine...
  27. doi request reprint Whose transplant function fails after ureteral revision following kidney transplantation?
    C Doehn
    Department of Urology, University of Lubeck Medical School, Lubeck, Germany
    Transplant Proc 42:1716-8. 2010
    ..In a retrospective analysis, we compared patients with versus without loss of transplant function after operative revision for a ureteral complication...
  28. ncbi request reprint Elevation of CA 19-9 in giant hydronephrosis induced by a renal calculus
    A Meyer
    Department of Urology, Medical University of Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    Urology 63:381-2. 2004
    ..Posttreatment CA 19-9 levels of patients with hydronephrosis have to be monitored closely to safely exclude malignant disease...
  29. ncbi request reprint Intra-abdominal abscess due to patient non-compliance after construction of an ileal neobladder: case report and review of the literature
    C Doehn
    Department of Urology, Medical University of Lubeck, Germany
    Int J Urol 6:264-7. 1999
    ..A case report of patient with an intra-abdominal abscess 8 weeks after radical cystectomy and construction of an ileal neobladder is presented...
  30. ncbi request reprint Fatal basilar artery thrombosis after chemotherapy for testicular cancer
    C Doehn
    Department of Urology, Medical University of Lubeck, Lubeck, Germany
    Urol Int 65:43-5. 2000
    ..He died 14 h after hospital admission. Cerebrovascular events related to cisplatin-based chemotherapy are rare, however, these potentially fatal events should be kept in mind when treating patients with testicular cancer...
  31. ncbi request reprint [Postoperative polyuria after laparoscopic adrenalectomy for pheochromocytoma]
    C E Blietz
    Klinik und Poliklinik fur Urologie, Universitätsklinikum Schleswig Holstein UK SH, Campus Lubeck, Ratzeburger Allee 160, 23538 Lubeck
    Aktuelle Urol 37:369-71. 2006
    ..In our case a normalisation of the urine output was observed after few days. A further treatment with vasopressin was not undertaken as the osmolality at all times was in normal range...
  32. ncbi request reprint Nonrandomized comparison of open flank versus laparoscopic nephrectomy in 249 patients with benign renal disease
    P Fornara
    Department of Urology, , Ratzeburger Allee 160, , Germany
    Eur Urol 40:24-31. 2001
    ..However, in experienced centers the laparoscopic technique should be offered to patients with benign renal disease who are scheduled for elective nephrectomy...
  33. ncbi request reprint [Surgical therapy of penis carcinoma]
    C Doehn
    Klinik und Poliklinik fur Urologie, Medizinische Universitat, Ratzeburger Allee 160, 23538 Lubeck
    Urologe A 40:303-7. 2001
    ..In cases of inguinal lymph node metastasis, removal of the iliac lymph nodes (one- or two-step procedure) is necessary...
  34. ncbi request reprint [Penile skin necrosis after application of a ring and defect coverage by a skin mesh graft]
    M Sommerauer
    Klinik und Poliklinik fur Urologie, Universitätsklinikum Schleswig Holstein UK SH, Campus Lubeck, Ratzeburger Allee 160, 23538 Lubeck
    Aktuelle Urol 37:376-8. 2006
    ..Penile strangulations are rare and always need an individual emergency treatment. Functional impairment and loss of organ integrity are the most serious complications...
  35. ncbi request reprint Primary treatment of condylomata acuminata with viable bacillus Calmette-Guerin
    A Bohle
    Department of Urology, Medical University of Lubeck, Lubeck, Germany
    J Urol 165:834-6. 2001
    ..To our knowledge we report the first successful primary treatment of genital warts with topical bacillus Calmette-Guerin (BCG) and provide long-term followup in a group of adjuvant treated patients with recurrent condylomata acuminata...
  36. ncbi request reprint [Intravesical cidofovir--instillation therapy for polyomavirus-associated hemorrhagic cystitis after bone marrow transplantation]
    O Walden
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck, 23538, Ratzeburger Allee 160, Lubeck
    Urologe A 46:535-7. 2007
    ..Sequential to these procedures, local instillation with cidofovir into the bladder was started to treat a suspected infection with polyomavirus and the gross hematuria stopped within a few days...
  37. ncbi request reprint [Bone formation in the ureter. Osseous metaplasia of an obstructed ureter]
    A J Meyer
    Klinik und Poliklinik fur Urologie, UK S H, Campus Lubeck, Lubeck
    Urologe A 45:1438-40. 2006
    ..Osseous metaplasia may therefore be considered a differential diagnosis of calcification of the upper urinary tract in the absence of urolithiasis...
  38. ncbi request reprint Value of acute-phase proteins in the differential diagnosis of acute scrotum
    C Doehn
    Department of Urology, Head Prof Dr D Jocham, Medical University of Lubeck, Germany
    Eur Urol 39:215-21. 2001
    ..However, the differential diagnosis may be difficult in some cases. In a retrospective study, we investigated the value of acutephase proteins in serum and plasma from patients with an acute scrotum...
  39. doi request reprint [Atypical metastasis of renal cell carcinoma. Contribution of comparative genomic hybridisation to diagnosis]
    B Kazarians
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, 23538 Lubeck
    Urologe A 49:407-10. 2010
    ..We report the case of a 35-year-old patient with renal cell carcinoma in whom only CGH could help differentiate between a second primary malignancy in the bladder and an atypical bladder metastasis...
  40. doi request reprint [Recurrent bladder cancer after BCG instillation therapy. Local therapy options?]
    J M Laturnus
    Klinik und Poliklinik fur Urologie, Universitätsklinikum Schleswig Holstein Campus Luebeck, Ratzeburger Allee 160, 23538, Lubeck, Deutschland
    Urologe A 51:1209-19. 2012
    ..Device-assisted intravesical strategies, such as mitomycin-EMDA or chemohyperthermia are candidates to keep in mind for the near future. Finally, cystectomy results in the best disease-specific survival in patients with BCG failure...
  41. doi request reprint [Human placental alkaline phosphatase (hPLAP) is the most frequently elevated serum marker in testicular cancer]
    A Neumann
    Klink und Poliklinik für Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck
    Aktuelle Urol 42:311-5. 2011
    ..Histological subtypes are seminoma, non-seminoma and mixed tumours (partly seminoma and partly non-seminoma). The aim of this study was to determine the value of different tumour markers in the primary diagnosis of testicular cancer...
  42. ncbi request reprint Technology evaluation: CV-787, Calydon Inc
    C Doehn
    Department of Urology, Medical University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Curr Opin Mol Ther 3:204-10. 2001
    ..The primary objectives of this trial are to determine the safety, tolerability, and PSA efficacy of CV-787 administered intravenously to patients with end-stage prostate cancer [384039]...
  43. ncbi request reprint Intravesical bacillus Calmette-Guerin versus mitomycin C for superficial bladder cancer: a formal meta-analysis of comparative studies on recurrence and toxicity
    A Bohle
    Department of Urology, Medical University of Lubeck, Lubeck, Germany
    J Urol 169:90-5. 2003
    ..We compare the therapeutic efficacy and toxicity of intravesical bacillus Calmette-Guerin (BCG) with mitomycin C on recurrence of stages Ta and T1 bladder carcinoma...
  44. doi request reprint [How accurate is the correlation between clinical and pathological TNM stages in renal tumours?]
    J Frommhold
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Germany
    Aktuelle Urol 42:247-51. 2011
    ..We have investigated the agreement between tumour size determined by preoperative computed tomography (CT) and pathological tumour size...
  45. ncbi request reprint Laparoscopic nephrectomy in young-old, old-old, and oldest-old adults
    P Fornara
    Department of Urology, , Germany
    J Gerontol A Biol Sci Med Sci 56:M287-91. 2001
    ..Laparoscopy should be regarded as the primary therapeutic option for nephrectomy for benign disease in these patients...
  46. ncbi request reprint Technology evaluation: Abarelix, Praecis pharmaceuticals
    C Doehn
    Department of Urology, Medical University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
    Curr Opin Mol Ther 2:579-85. 2000
    ..In October 1999, Merrill Lynch predicted sales in 2003 of EUR 100 million [346209] and Lehman Brothers predicted sales of US$50 million in 2002 rising to a peak of US$150 million in 2010 [346267]...
  47. doi request reprint Altered transcription profiles of key-enzymes of androgen biosynthesis in genital skin fibroblasts from patients with 46,XY disorders of sex development (DSD)
    U Hoppe
    Department of Pediatrics and Adolescent Medicine, University of Lubeck, Lubeck, Germany
    Sex Dev 1:230-7. 2007
    ..A role for an altered expression pattern of different enzymes of steroidogenesis in the etiology of genital malformations in some patients may be postulated...
  48. ncbi request reprint [Quality of life in urologic oncology: new aspects]
    C Doehn
    Klinik und Poliklinik fur Urologie, Universitätsklinikum Schleswig Holstein Campus Lübeck, Deutschland
    Onkologie 26:30-4. 2003
    ..Beside the development of disease-specific questionnaires, a future major issue is the standardized determination of the parameter quality of life to achieve a basis to compare the results of different studies...
  49. ncbi request reprint [Spontaneous hemorrhage of the adrenal gland during pregnancy]
    B Kazarians
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, UK S H, Campus Lubeck
    Aktuelle Urol 38:403-5. 2007
    ..Spontaneous hemorrhage is a rare cause of masses in the adrenal gland and must be differentiated from hemorrhage caused by trauma, neoplasm or metastases...
  50. ncbi request reprint Spontaneous external drainage of renal abscess through persistent nephrostomy tract eleven years after percutaneous nephrolithotomy
    H Suttmann
    Department of Urology, University of Lubeck Medical School, Lubeck, Germany
    Urol Int 75:88-90. 2005
    ..Nephrostomy tracts can open up even after several years to provide an exit path for infected urine or renal abscess drainage...
  51. ncbi request reprint Why is urological laparoscopy minimally invasive?
    P Fornara
    Department of Urology, Medical University of Lubeck, Lubeck, Germany
    Eur Urol 37:241-50. 2000
    ..We report a prospective, controlled, nonrandomized animal and patient study to determine the systemic response to laparoscopic and open surgical procedures...
  52. doi request reprint Mode-of-action, efficacy, and safety of a homologous multi-epitope vaccine in a murine model for adjuvant treatment of renal cell carcinoma
    Christian Doehn
    Department of Urology, University of Lubeck Medical School, Lubeck, Germany
    Eur Urol 56:123-31. 2009
    ..This clinical trial focused on efficacy and did not investigate end-points relating to mode-of-action of the vaccine. In a murine model we investigated mode-of-action, efficacy, and safety of a homologous RENCA cell-based vaccine...
  53. ncbi request reprint Quality of life in elderly men with androgen deficiency
    D Finas
    Department of Obstetrics and Gynaecology, University of Lubeck, Lubeck, Germany
    Andrologia 38:48-53. 2006
    ..A question of interest is whether this difference remains detectable if testosterone is supplemented to androgen-deficient men. Whether testosterone supplementation is beneficial to these patients has to be carefully considered...
  54. pmc Urinary bladder cancer in Wegener's granulomatosis: is it more than cyclophosphamide?
    B Hellmich
    Poliklinik fur Rheumatologie, Universitätsklinkum Schleswig Holstein, Lubeck, Germany
    Ann Rheum Dis 63:1183-5. 2004
  55. ncbi request reprint Leiomyo-adenomatoid tumor of the epididymis
    I Kausch
    Department of Urology, Medical University of Lubeck, Lubeck, Germany
    J Urol 168:636. 2002
  56. ncbi request reprint Burn-out of urologists in the county of Schleswig-Holstein, Germany: a comparison of hospital and private practice urologists
    A Bohle
    Department of Urology, Medical University of Lubeck, Lubeck, Germany
    J Urol 165:1158-61. 2001
    ..The degree of burn-out was estimated among urologists in the German federal county of Schleswig-Holstein, with special emphasis on differences related to age, qualification and hospital versus private practice...
  57. doi request reprint [Endourological lithotripsy for stone removal: accidental fragmentation of dormia basket and guidewire - a brief overview]
    J Cordes
    Klinik für Urologie, Campus Lubeck, Universitatsklinikum Schleswig Holstein, Ratzeburger Allee 160, 23538 Lubeck, Deutschland
    Urologe A 49:1365-7. 2010
    ..In this article we describe the energy needed for destroying specific foreign bodies and what currently and in the future will be the best way to avoid this problem...
  58. ncbi request reprint Cytokine and vaccine therapy of kidney cancer
    Christian Doehn
    Department of Urology, University of Lubeck Medical School, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Expert Rev Anticancer Ther 4:1097-111. 2004
    ..Vaccine therapy of metastatic kidney cancer has been investigated only in Phase I and II studies with limited clinical benefit. Based on the current literature there is a clear need for new approaches in metastatic kidney cancer...
  59. doi request reprint The role of surgery in clinical management of patients with metastatic papillary renal cell carcinoma
    Thomas Steiner
    Department of Urology, University Hospital Jena, Lessingstr 1, 07743 Jena, Germany
    J Cancer Res Clin Oncol 136:905-10. 2010
    ..This study aimed to assess the relevance of surgical and systemic options used in treatment of these patients prior to the recent era of targeted therapies...
  60. doi request reprint [Non-muscle invasive transitional cell carcinoma of the bladder. New developments in diagnostics and therapy]
    M Sommerauer
    Klinik und Poliklinik fur Urologie, UK SH Campus Lübeck, Ratzeburgerallee 160, 23568 Lubeck
    Urologe A 51:791-7. 2012
    ..New therapeutic options are thermochemotherapy and mitomycin-C electromotive drug administration (MMC-EMDA) as well as gemcitabine and apaziquone for intravesical administration...
  61. ncbi request reprint Renal transplant lithiasis
    C Doehn
    Department of Urology, Medical University of Lubeck, Lubeck, Germany
    Transplant Proc 34:2222-3. 2002
  62. ncbi request reprint Optimal treatment of systemic bacillus Calmette-Guérin infection: investigations in an animal model
    C Durek
    Department of Urology, Medical University of Lubeck, Lubeck, Germany
    J Urol 168:826-31. 2002
    ..Furthermore, the antitumor effectiveness of intravesical BCG with simultaneous application of fluoroquinolones and/or steroids was tested...
  63. ncbi request reprint Uretero-iliac artery fistula--a rare cause of massive hematuria
    P Hildebrand
    Department of Surgery, University of Schleswig Holstein, Lubeck, Germany
    Scand J Urol Nephrol 38:434-5. 2004
    ..The authors report a case of a fistula between the right ureter and right common iliac artery...
  64. ncbi request reprint Inhibition of Ki-67 in a renal cell carcinoma severe combined immunodeficiency disease mouse model is associated with induction of apoptosis and tumour growth inhibition
    Ingo Kausch
    Department of Urology, University of Lubeck, Medical School, Ratzeburger Allee 160, 23538 Lubeck, Germany
    BJU Int 95:416-20. 2005
    ....
  65. ncbi request reprint Technology evaluation: PROSTVAC, Therion
    Christian Doehn
    Department of Urology, University of Lübeck Medial School, Germany
    Curr Opin Mol Ther 4:528-34. 2002
    ..In February 2000, phase II trials had commenced. By October 2001, the drug was undergoing four phase II trials...
  66. ncbi request reprint Technology evaluation: Onyvax-P, Onyvax
    Christian Doehn
    University of Lubeck Medical School, Department of Urology, Lubeck, Germany
    Curr Opin Mol Ther 7:511-9. 2005
    ..Onyvax is developing Onyvax-P, an allogeneic whole-cell vaccine, for the potential treatment of prostate cancer. The vaccine is currently undergoing phase II clinical trials...
  67. ncbi request reprint Prostate cancer vaccines: current status and future potential
    Christian Doehn
    Department of Urology, University of Lubeck Medical School, Lubeck, Germany
    BioDrugs 22:71-84. 2008
    ....
  68. ncbi request reprint Drug evaluation: Therion's rV-PSA-TRICOM + rF-PSA-TRICOM prime-boost prostate cancer vaccine
    Christian Doehn
    University of Lubeck Medical School, Department of Urology, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Curr Opin Mol Ther 9:183-9. 2007
    ..1 and lymphocyte function-associated antigen-3), and a booster injection with a fowlpox virus expressing the same combination, for the potential treatment of prostate cancer. Phase II clinical trials are underway...
  69. ncbi request reprint Expression of C-reactive protein by renal cell carcinomas and unaffected surrounding renal tissue
    Wolfram J Jabs
    Department of Medicine I, Division of Nephrology, University of Luebeck School of Medicine, Germany
    Kidney Int 68:2103-10. 2005
    ..Renal tubular epithelial cells are capable of synthesizing CRP. Although production of interleukin (IL)-6 has been described in RCC, CRP expression by carcinoma cells has yet not been investigated...