Hubert Schrezenmeier

Summary

Affiliation: Institute of Transfusion Medicine and Immunology
Country: Germany

Publications

  1. doi request reprint Paroxysmal nocturnal haemoglobinuria treatment with eculizumab is associated with a positive direct antiglobulin test
    B Höchsmann
    Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service Baden Wuerttemberg, Hessen, Germany
    Vox Sang 102:159-66. 2012
  2. pmc Paroxysmal nocturnal hemoglobinuria (PNH): higher sensitivity and validity in diagnosis and serial monitoring by flow cytometric analysis of reticulocytes
    Britta Höchsmann
    DRK Blood Donor Service, Baden Württemberg Hessia, Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Ulm, Germany
    Ann Hematol 90:887-99. 2011
  3. ncbi request reprint Bacterial contamination of platelet concentrates: results of a prospective multicenter study comparing pooled whole blood-derived platelets and apheresis platelets
    Hubert Schrezenmeier
    Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Red Cross Blood Donor Service Baden Württemberg Hessia, and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany
    Transfusion 47:644-52. 2007
  4. doi request reprint Carboxylated superparamagnetic iron oxide particles label cells intracellularly without transfection agents
    Volker Mailänder
    Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Institute of Transfusion Medicine, University of Ulm, Helmholtzstr 10, 89081 Ulm, Germany
    Mol Imaging Biol 10:138-46. 2008
  5. pmc Quality of tumor lysates used for pulsing dendritic cells is influenced by the method used to harvest adherent tumor cells
    Gloria Isabelle Herzog
    Institute of Transfusion Medicine, University of Ulm, Germany
    BMC Res Notes 4:153. 2011
  6. doi request reprint Eculizumab opens a new era of treatment for paroxysmal nocturnal hemoglobinuria
    Hubert Schrezenmeier
    Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Red Cross Blood Service Baden Württemberg Hessen, Germany
    Expert Rev Hematol 2:7-16. 2009
  7. doi request reprint Automatic interface-controlled apheresis collection of stem/progenitor cells: results from an autologous donor validation trial of a novel stem cell apheresis device
    Peter Reinhardt
    German Red Cross Blood Service Baden Württemberg Hessen and Institute of Clinical Transfusion Medicine and Immunogenetics, University of Ulm, Ulm, Germany
    Transfusion 51:1321-30. 2011
  8. doi request reprint Human mesenchymal stem cells respond to native but not oxidized damage associated molecular pattern molecules from necrotic (tumor) material
    Ramin Lotfi
    Institute for Transfusion Medicine, University of Ulm, Ulm, Germany
    Eur J Immunol 41:2021-8. 2011
  9. doi request reprint Leukemic progenitor cells are susceptible to targeting by stimulated cytotoxic T cells against immunogenic leukemia-associated antigens
    Vanessa Schneider
    Department of Internal Medicine III, University of Ulm, Ulm, Germany
    Int J Cancer 137:2083-92. 2015
  10. pmc Effect of high-dose irradiation on human bone-marrow-derived mesenchymal stromal cells
    Natalie Fekete
    1 Institut für Klinische Transfusionsmedizin und Immungenetik Ulm, DRK Blutspendedienst Baden Württemberg Hessen, Universitatsklinikum Ulm, Ulm, Germany
    Tissue Eng Part C Methods 21:112-22. 2015

Collaborators

  • Robert Mohle
  • Ludwika Kreja
  • Markus T Rojewski
  • W A Flegel
  • S Kaiser
  • Michael Schmidt
  • Peter Ponsaerts
  • Ramin Lotfi
  • Natalie Fekete
  • Britta Höchsmann
  • Gloria Isabelle Herzog
  • Markus Wiesneth
  • Volker Mailänder
  • Myriam Ricarda Lorenz
  • Christof Weinstock
  • Vanessa Schneider
  • Alexander Erle
  • B Höchsmann
  • Jochen Greiner
  • Ghasem Solgi
  • Christian Nienhaus
  • Tatjana Yildiz
  • Peter Reinhardt
  • Karin Fuchs
  • Paul Walther
  • Katharina Landfester
  • Anna Musyanovych
  • Juliane M Wiehe
  • Verena Holzapfel
  • Gerlinde Schmidtke-Schrezenmeier
  • Susanne Hofmann
  • Susann Ihme
  • Lu Zhang
  • Konstanze Dohner
  • Michaela Feuring-Buske
  • Katja Weisel
  • Alain Langonne
  • Lothar Kanz
  • Christiane Dorn
  • Christian Buske
  • Lars Bullinger
  • Elisa Maria Amann
  • Luc Sensebe
  • Daniel Furst
  • Marlies Götz
  • Hartmut Dohner
  • I von Zabern
  • R Leichtle
  • Halvard Bonig
  • Susanne Bräuninger
  • Kristin Thorausch
  • Heike Bialleck
  • Denis S Wiegmann
  • Richard Smith
  • Erhard Seifried
  • Judith Eisenbacher
  • Donna Beer-Stolz
  • Michael Thomas Lotze
  • Richard Anthony DeMarco
  • JAMES JOSEPH LEE
  • Anna Rubartelli
  • Joerg M Homann
  • Vinzenz Hombach
  • Jan Torzewski
  • Oliver Zimmermann
  • Desiree Kronawitter
  • Karin Nothelfer
  • Hendrik Frank

Detail Information

Publications15

  1. doi request reprint Paroxysmal nocturnal haemoglobinuria treatment with eculizumab is associated with a positive direct antiglobulin test
    B Höchsmann
    Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service Baden Wuerttemberg, Hessen, Germany
    Vox Sang 102:159-66. 2012
    ..These published clinical trials investigated a highly selected patient population. Therefore, it seems important to study this topic in a general PNH patient population with a longer follow-up...
  2. pmc Paroxysmal nocturnal hemoglobinuria (PNH): higher sensitivity and validity in diagnosis and serial monitoring by flow cytometric analysis of reticulocytes
    Britta Höchsmann
    DRK Blood Donor Service, Baden Württemberg Hessia, Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Ulm, Germany
    Ann Hematol 90:887-99. 2011
    ..Among the markers in our panel, CD58 and CD59 on reticulocytes, CD24/66b, and eventually FLAER on granulocytes as well as CD14 on monocytes were most effective for flow cytometric diagnosis of GPI deficiency...
  3. ncbi request reprint Bacterial contamination of platelet concentrates: results of a prospective multicenter study comparing pooled whole blood-derived platelets and apheresis platelets
    Hubert Schrezenmeier
    Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Red Cross Blood Donor Service Baden Württemberg Hessia, and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany
    Transfusion 47:644-52. 2007
    ....
  4. doi request reprint Carboxylated superparamagnetic iron oxide particles label cells intracellularly without transfection agents
    Volker Mailänder
    Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Institute of Transfusion Medicine, University of Ulm, Helmholtzstr 10, 89081 Ulm, Germany
    Mol Imaging Biol 10:138-46. 2008
    ..A steady increase in uptake of nanoparticles was detected with a higher density of carboxyl groups showing the relevance of charged groups as in the case of Resovist. Aggregation of these polymeric nanoparticles was not found...
  5. pmc Quality of tumor lysates used for pulsing dendritic cells is influenced by the method used to harvest adherent tumor cells
    Gloria Isabelle Herzog
    Institute of Transfusion Medicine, University of Ulm, Germany
    BMC Res Notes 4:153. 2011
    ..abstract:..
  6. doi request reprint Eculizumab opens a new era of treatment for paroxysmal nocturnal hemoglobinuria
    Hubert Schrezenmeier
    Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Red Cross Blood Service Baden Württemberg Hessen, Germany
    Expert Rev Hematol 2:7-16. 2009
    ..Experience from the pilot study and the Phase III pivotal program of eculizumab in PNH will be summarized and the impact of eculizumab on the future treatment of PNH will be discussed...
  7. doi request reprint Automatic interface-controlled apheresis collection of stem/progenitor cells: results from an autologous donor validation trial of a novel stem cell apheresis device
    Peter Reinhardt
    German Red Cross Blood Service Baden Württemberg Hessen and Institute of Clinical Transfusion Medicine and Immunogenetics, University of Ulm, Ulm, Germany
    Transfusion 51:1321-30. 2011
    ....
  8. doi request reprint Human mesenchymal stem cells respond to native but not oxidized damage associated molecular pattern molecules from necrotic (tumor) material
    Ramin Lotfi
    Institute for Transfusion Medicine, University of Ulm, Ulm, Germany
    Eur J Immunol 41:2021-8. 2011
    ..Based on our results, oxidizing conditions should be considered for therapeutic approaches that target the tumor microenvironment...
  9. doi request reprint Leukemic progenitor cells are susceptible to targeting by stimulated cytotoxic T cells against immunogenic leukemia-associated antigens
    Vanessa Schneider
    Department of Internal Medicine III, University of Ulm, Ulm, Germany
    Int J Cancer 137:2083-92. 2015
    ..LAA-specific T cells are able to hamper LSC in immunoassays and in a mouse model, which suggests that immunotherapeutic approaches have the potential to target malignant stem cells...
  10. pmc Effect of high-dose irradiation on human bone-marrow-derived mesenchymal stromal cells
    Natalie Fekete
    1 Institut für Klinische Transfusionsmedizin und Immungenetik Ulm, DRK Blutspendedienst Baden Württemberg Hessen, Universitatsklinikum Ulm, Ulm, Germany
    Tissue Eng Part C Methods 21:112-22. 2015
    ..Cells surviving irradiation retained their trilineage differentiation capacity and surface marker profile but changed their cytokine secretion profile and became prematurely senescent. ..
  11. doi request reprint Successful use of eculizumab for treatment of an acute hemolytic reaction after ABO-incompatible red blood cell transfusion
    Christof Weinstock
    Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Service Baden Württemberg Hessen, Institute of Transfusion Medicine, University of Ulm, Ulm, Germany
    Transfusion 55:605-10. 2015
    ..Therapeutic inhibition of the complement cascade in case of ABO-incompatible RBC transfusion would be desirable to ameliorate the signs and symptoms and to improve the outcome of the reaction...
  12. doi request reprint GMP-compliant isolation and expansion of bone marrow-derived MSCs in the closed, automated device quantum cell expansion system
    Markus T Rojewski
    Institut fur Transfusionsmedizin, Universitat Ulm, Ulm, Germany
    Cell Transplant 22:1981-2000. 2013
    ..Both isolation and expansion are possible using FCS or PL as supplement. Coating of the hollow fibers of the bioreactor is mandatory when loading MSCs. Fibronectin, PL, and human plasma may serve as coating reagents. ..
  13. pmc mRNA-mediated gene delivery into human progenitor cells promotes highly efficient protein expression
    Juliane M Wiehe
    Department of Internal Medicine II, University of Ulm, Ulm, Germany
    J Cell Mol Med 11:521-30. 2007
    ..It may be useful to transiently manipulate stem cell characteristics and thus combine principles of gene therapy and tissue engineering...
  14. doi request reprint Eosinophils oxidize damage-associated molecular pattern molecules derived from stressed cells
    Ramin Lotfi
    Institut fur klinische Transfusionsmedizin und Immungenetik Ulm, Institut fur Transfusionsmedizin Universitat Ulm, Ulm, Germany
    J Immunol 183:5023-31. 2009
    ..Novel therapeutic strategies may be considered by advancing oxidative denaturation of released necrotic material using Eos or other aerobic strategies...
  15. ncbi request reprint Uptake of functionalized, fluorescent-labeled polymeric particles in different cell lines and stem cells
    Myriam Ricarda Lorenz
    Department of Transfusion Medicine, Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, University of Ulm, Helmholtzstr 10, 89081 Ulm, Germany
    Biomaterials 27:2820-8. 2006
    ..Scanning electron microscopy showed microvilli to be involved in this process...