Research Topics
| Michael SchmidtSummaryAffiliation: Institute of Transfusion Medicine and Immunology Country: Germany Publications
| Collaborators
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Detail Information
Publications
Blood screening for influenzaMichael Kai Hourfar
German Red Cross, Frankfurt, Germany
Emerg Infect Dis 13:1081-3. 2007..Analytical sensitivity of the method was 804 geq/mL and 444 geq/mL for generic influenza primers and influenza (H5N1) subtype-specific primers. This study demonstrates that such screening for influenza viruses is feasible...
Blood donor screening for parvovirus B19 in Germany and AustriaMichael Schmidt
Institute of Transfusion Medicine and Immunohematology, Johann Wolfgang Goethe University, German Red Cross, Institute Frankfurt, Sandhofstrasse 1, 60528 Frankfurt am Main, Germany
Transfusion 47:1775-82. 2007..To increase blood safety, all blood donations to our blood donor service have been screened by a B19 minipool real-time nucleic acid testing (NAT) since April 2000. Additional customers have been screened since the summer of 2003...
Blood donor screening with cobas s 201/cobas TaqScreen MPX under routine conditions at German Red Cross institutesM Schmidt
Institute of Transfusion Medicine and Immunohematology, German Red Cross, Johann Wolfgang Goethe University, Frankfurt, Germany
Vox Sang 98:37-46. 2010..With the new cobas s 201/cobas TaqScreen MPX, a fully automated extraction method and a multiplex amplification system specifically adapted to the needs of blood donation services is available...- A comparison of three rapid bacterial detection methods under simulated real-life conditionsMichael Schmidt
Institute of Transfusion Medicine and Immunohematology, German Red Cross, Johann Wolfgang Goethe University, Frankfurt, Germany
Transfusion 46:1367-73. 2006..This study compares three rapid bacterial detection methods by imitating real-life conditions... - Experience of German Red Cross blood donor services with nucleic acid testing: results of screening more than 30 million blood donations for human immunodeficiency virus-1, hepatitis C virus, and hepatitis B virusMichael K Hourfar
Institute of Transfusion and Immunohematology, German Red Cross Baden Württemberg Hessen, Johann Wolfgang Goethe University, Frankfurt, Germany
Transfusion 48:1558-66. 2008..In 1997, nucleic acid amplification technique (NAT)-testing was introduced at the German Red Cross (GRC) blood donor services to reduce this diagnostic window period (WP)... - High-throughput purification of viral RNA based on novel aqueous chemistry for nucleic acid isolationMichael K Hourfar
Institute of Transfusion Medicine and Immunohaematology, German Red Cross, Johann Wolfgang Goethe University, Frankfurt, Germany
Clin Chem 51:1217-22. 2005..However, commercially available magnetic-bead-based assays either lack the sensitivity required for viral diagnostics or are disproportionately expensive... - Recipients potentially infected with parvovirus B19 by red blood cell productsMichael Kai Hourfar
Institute for Transfusion Medicine and Immunohematology, Johann Wolfgang Goethe University, German Red Cross, Baden Württemberg Hessen, Institute Frankfurt, Frankfurt, Germany
Transfusion 51:129-36. 2011..In this study, we evaluated the infectivity of B19-positive blood products in relation to the virus concentration in the transfused blood component... - A new one-platform flow cytometric method for residual cell counting in platelet concentratesMichael Schmidt
Institute of Transfusion Medicine and Immunohematology, German Red Cross, Johann Wolfgang Goethe University, Frankfurt, Germany
Transfusion 49:2604-11. 2009..Due to low levels of residual cells in final products, there is still a need for fast, reliable, and sensitive methods of automated detection of these cell types... - Comparison of two real-time quantitative assays for detection of severe acute respiratory syndrome coronavirusMichael K Hourfar
Institute of Transfusion Medicine and Immunohematology, German Red Cross, Johann Wolfgang Goethe University, Frankfurt, Germany
J Clin Microbiol 42:2094-100. 2004..The Artus assay is also suitable for detection of SARS CoV at the low concentrations found in serum samples... - First transmission of human immunodeficiency virus Type 1 by a cellular blood product after mandatory nucleic acid screening in GermanyMichael Schmidt
Institute of Transfusion Medicine and Immunohematology, German Red Cross, and the Institute for Medical Virology, Johann Wolfgang Goethe University, Frankfurt, Germany
Transfusion 49:1836-44. 2009..The transfusion-transmitted infection had been identified by a donor-related lookback started in April 2007 after anti-HIV seroconversion... - Nucleic acid test screening of blood donors for orthopoxviruses can potentially prevent dispersion of viral agents in case of bioterrorismMichael Schmidt
Institute of Transfusion Medicine and Immunohematology, German Red Cross, Johann Wolfgang Goethe University, Frankfurt, Germany
Transfusion 45:399-403. 2005..Real-time polymerase chain reaction (PCR) followed by melting analysis was developed for fast and safe analysis and allows differentiation of VAR from other orthopoxviruses (OPVs) like vaccinia or camelpox virus... - Bacterial contamination of platelet concentrates: results of a prospective multicenter study comparing pooled whole blood-derived platelets and apheresis plateletsHubert Schrezenmeier
Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, Red Cross Blood Donor Service Baden Württemberg Hessia, and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany
Transfusion 47:644-52. 2007.... - Optimized Scansystem platelet kit for bacterial detection with enhanced sensitivity: detection within 24 h after spikingMichael Schmidt
Institute of Transfusion Medicine and Immunohematology, German Red Cross, Johann Wolfgang Goethe University, Frankfurt, Germany
Vox Sang 89:135-9. 2005..In this spiking study, we evaluated the new optimized Scansystem Platelet Kit detection method for use on apheresis platelets... - Sufficient blood, safe blood: can we have both?Halvard Bonig
German Red Cross Blood Service Baden Württemberg Hesse and Institute for Transfusion Medicine and Immunohematology of Goethe University, Frankfurt, Germany
BMC Med 10:29. 2012..Recruitment of this group will benefit the availability of blood without jeopardizing the current excellent safety profile of blood... - NAT screening of blood donors for severe acute respiratory syndrome coronavirus can potentially prevent transfusion associated transmissionsMichael Schmidt
Institute of Transfusion Medicine and Immunohematology, German Red Cross, Johan Wolfgang Goethe University, Frankfurt, Germany
Transfusion 44:470-5. 2004..The severe acute respiratory syndrome (SARS) was first described in February 2003. Close contact with symptomatic patients appears to be the main route of transmission, whereas blood transfusion transmission could not be ruled out... - West Nile virus and blood product safety in GermanyChrista Pfleiderer
Paul Ehrlich Institut, Abteilung Virologie, Langen, Germany
J Med Virol 80:557-63. 2008..A well-characterized WNV reference material was prepared, showing 340 WNV-RNA copies per infectious dose... - High-frequency oscillatory ventilation reduces lung inflammation: a large-animal 24-h model of respiratory distressRalf M Muellenbach
Department of Anaesthesiology, University of Wuerzburg, Oberduerrbacher Strasse 6, 97080 Wuerzburg, Germany
Intensive Care Med 33:1423-33. 2007..The aim of this study was to compare gas exchange, lung histopathology and inflammatory cytokine expression during lung-protective pressure-controlled ventilation (PCV) and HFOV in a long-term large-animal model of ARDS... - [Introduction of the DRG system in Germany: problems and perspectives from the point of view of the German Hospital Federation]Michael Schmidt
Deutsche Krankenhausgesellschaft, Dusseldorf
Z Arztl Fortbild Qualitatssich 96:521-6. 2002..Current hospital planning will be turned inside out. Also, the interfaces between the hospital sector on the one hand and other areas of care on the other will be put to a real test of endurance... - Exposure to high stress in the intensive care unit may have negative effects on health-related quality-of-life outcomes after cardiac surgeryGustav Schelling
Department of Anesthesiology, Ludwig-Maximilians-University, Munich, Germany
Crit Care Med 31:1971-80. 2003..52, p <.01). CONCLUSIONS: Exposure to high stress in the cardiovascular intensive care unit can have negative effects on HRQL outcomes of cardiac surgery... - Yield of hepatitis C virus nucleic acid testing among antibody-reactive or confirmed-positive samplesMichael Schmidt
Transfusion 45:1040-2. 2005 - Bacteria detection by flow cytometryOliver Karo
Paul Ehrlich Institute, Langen, Germany
Clin Chem Lab Med 46:947-53. 2008..e., transfer of samples from platelet concentrates into a satellite bag, incubation of the latter at 37 degrees C, and measuring the contaminating bacteria in a flow cytometer... - Identification and characterization of novel adeno-associated virus isolates in ATCC virus stocksMichael Schmidt
Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institute of Health, Bethesda, MD 20892, USA
J Virol 80:5082-5. 2006..While the novel AAVs had high sequence homologies and required sialic acid for cell binding and transduction, differences were observed in lectin competition, resulting in distinct tropisms in human cancer cell lines... - Hepatitis B virus genotype G monoinfection and its transmission by blood componentsMichael Chudy
Paul Ehrlich Institut, Langen, Germany
Hepatology 44:99-107. 2006..In conclusion, this reported case of an HBV infection was caused exclusively by genotype G... - Resection of malignant tumors invading the vena cava: perioperative complications and long-term follow-upAndreas Kuehnl
Department of Surgery, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
J Vasc Surg 46:533-40. 2007..This study was performed to evaluate our experiences with resection of the vena cava for malignant tumors, with a special focus on secondary tumors involving the inferior caval vein... - Cutaneous melanoma in childhood and adolescence: an analysis of 36 patientsMonika H Schmid-Wendtner
Department of Dermatology and Allergology and Tumor Registry, Ludwig-Maximilians-University, Munich, Germany
J Am Acad Dermatol 46:874-9. 2002..Reduction of the melanoma mortality rate in children and adolescents will be achieved through identification of patients at increased risk...