Research Topics
Species | J WraseSummaryAffiliation: Humboldt University Country: Germany Publications
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Detail Information
Publications
The influence of gender and emotional valence of visual cues on FMRI activation in humansS Klein
Central Institute of Mental Health, Mannheim, Germany
Pharmacopsychiatry 36:S191-4. 2003..In men fMRI activation was independent of stimulus valence. These results suggest to take gender differences into account when emotional paradigms are tested in functional brain imaging...
Development of alcohol-associated cues and cue-induced brain activation in alcoholicsJ Wrase
Department of Psychiatry of the Charité, Humboldt University of Berlin, Schumannstr 20 21, 10117, Berlin, Germany
Eur Psychiatry 17:287-91. 2002..These observations suggest that standardized pictures of alcoholic beverages can be used to assess brain circuits involved in the processing and evaluation of alcohol cues...
Neurotransmitter systems in alcohol dependenceA Heinz
Department of Psychiatry and Psychotherapy, CCM, Charite University Medicine, Berlin, Germany
Pharmacopsychiatry 42:S95-S101. 2009..g. between brain atrophy and genes associated with glutamatergic and dopaminergic neurotransmission...
[Aggressive and impulsive behavior: neurobiological models explain how affectregulation might work and social skills develop]T Kienast
Klinik für Psychiatrie und Psychotherapie der Charité, CCM, Universitatsmedizin Berlin
MMW Fortschr Med 149:29-32. 2007..The serotonin turnover of an individual is controlled by environmental influences in interaction with genetic factors. In this article, impulse control disorders will be discussed with regard to their origin and social effects...
Synergistic effects of the dopaminergic and glutamatergic system on hippocampal volume in alcohol-dependent patientsI Puls
Department of Psychiatry and Psychotherapy, CCM, Charite University Medicine, Berlin, Germany
Biol Psychol 79:126-36. 2008..These data are in line with prior studies supporting a role for dopamine-glutamate interaction in modulation of alcohol disease...
[Alcohol-related disorders: etiopathology and therapeutic considerations]J Hein
Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin, Berlin, Germany
Fortschr Neurol Psychiatr 75:10-7. 2007..The understanding of these neurobiological principles of alcohol-related disorders should contribute to enhance and improve their therapeutic options...
Alcohol-associated stimuli activate the ventral striatum in abstinent alcoholicsD F Braus
Central Institute of Mental Health, Mannheim, Federal Republic of Germany
J Neural Transm 108:887-94. 2001..This observation supports the hypothesis that alcohol use affects areas involved in brain reward circuits and that their stimulus-induced activation may be associated with an increased risk for relapse...
[Cue-induced alcohol craving. Neurobiological correlates and clinical relevance]J Wrase
, , , Germany
Nervenarzt 77:1051-2, 1055-8, 1060-3. 2006..These findings point to specific indications for psychotherapeutic and additive pharmacological treatment options...
Gene-gene effects on central processing of aversive stimuliM N Smolka
Department of Psychiatry, Technische Universitat Dresden, Dresden, Germany
Mol Psychiatry 12:307-17. 2007..Effects of 5-HTT and COMT genotypes did not affect brain processing of pleasant stimuli. These data indicate that functional brain imaging may be used to assess the interaction of multiple genes on the function of neuronal networks...
[Neurobiology of substance-related addiction: findings of neuroimaging]T Kienast
Klinik für Psychiatrie und Psychotherapie der Charité, CCM, Universitatsmedizin Berlin, Germany
Fortschr Neurol Psychiatr 76:S68-76. 2008..Besides discussing brain imaging studies on the neurobiological correlates of drug dependence, this review also presents studies on vulnerability factors that predispose individuals to excessive drug intake...
Midbrain serotonin transporter binding potential measured with [11C]DASB is affected by serotonin transporter genotypeM Reimold
Department of Nuclear Medicine and PET Center, University of Tubingen, Tubingen, Germany
J Neural Transm 114:635-9. 2007..In vitro and in vivo evidence suggests that [(11)C]DASB, a new 5-HTT ligand offers some advantages over the ligands used in previous studies in measuring 5-HTT density independent of synaptic levels of serotonin...
