Karsten H Weylandt

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Rethinking lipid mediators
    Karsten H Weylandt
    Department of Gastroenterology and Hepatology, Charite University Hospital, Campus Virchow, 13353 Berlin, Germany
    Lancet 366:618-20. 2005
  2. doi request reprint Omega-3 fatty acids and their lipid mediators: towards an understanding of resolvin and protectin formation
    Karsten H Weylandt
    Department of Gastroenterology, Hepatology and Endocrinology, Charite University Medicine, Rudolf Virchow Hospital, Berlin, Germany
    Prostaglandins Other Lipid Mediat 97:73-82. 2012
  3. pmc Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF-α
    Karsten H Weylandt
    Laboratory for Lipid Medicine and Technology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Carcinogenesis 32:897-903. 2011
  4. ncbi request reprint Colitis-associated colon tumorigenesis is suppressed in transgenic mice rich in endogenous n-3 fatty acids
    Johannes Nowak
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Carcinogenesis 28:1991-5. 2007
  5. pmc Acetylsalicylic Acid reduces the severity of dextran sodium sulfate-induced colitis and increases the formation of anti-inflammatory lipid mediators
    Thomas Köhnke
    Department of Gastroenterology, Hepatology and Endocrinology, Virchow Hospital, Charite Medical School, Free and Humboldt University of Berlin, 13353 Berlin, Germany Laboratory for Lipid Medicine and Technology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Biomed Res Int 2013:748160. 2013
  6. pmc Reduction of inflammation and chronic tissue damage by omega-3 fatty acids in fat-1 transgenic mice with pancreatitis
    Karsten H Weylandt
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Biochim Biophys Acta 1782:634-41. 2008
  7. pmc Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells
    Piet Habbel
    Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States
    World J Gastroenterol 15:1079-84. 2009
  8. doi request reprint Modulation of inflammatory cytokines by omega-3 fatty acids
    Jing X Kang
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Subcell Biochem 49:133-43. 2008
  9. doi request reprint Omega-6 docosapentaenoic acid-derived resolvins and 17-hydroxydocosahexaenoic acid modulate macrophage function and alleviate experimental colitis
    Cheng Ying Chiu
    Department of Hepatology, Gastroenterology and Endocrinology, Charite University Medicine Berlin, Campus Virchow Klinikum, Berlin, Germany
    Inflamm Res 61:967-76. 2012
  10. doi request reprint Fat-1 transgenic mice with elevated omega-3 fatty acids are protected from allergic airway responses
    Sueleyman Bilal
    Laboratory for Lipid Medicine and Technology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Biochim Biophys Acta 1812:1164-9. 2011

Collaborators

  • Jing X Kang
  • Martin Purschke
  • Yan Lu
  • C N Serhan
  • Bindi Dangi
  • Beate Gomolka
  • Piet Habbel
  • Johannes Nowak
  • Jingdong Wang
  • Thomas Köhnke
  • Cheng Ying Chiu
  • Michael Rothe
  • Daniel C Baumgart
  • Sueleyman Bilal
  • Christoph Schmöcker
  • Axel Dignass
  • Christian A Hudert
  • Yanping Sun
  • Xiangzhi Zhou
  • Süleyman Bilal
  • Cordula Dierkes
  • Nora R Huang
  • Dieter Manstein
  • Maik Schroeder
  • Elise Siegert
  • Wolf Hagen Schunck
  • Katrin Blossey
  • Bruce D Levy
  • Lijun Wu
  • Oliver Haworth
  • Cheng Wei He
  • Katja Lichopoj
  • Jing Dong Wang
  • Thomas Berg
  • Gisa Tiegs
  • Lena Kahlke
  • Jonathan N Glickman
  • Hartmut Lobeck
  • Song Hong

Detail Information

Publications14

  1. ncbi request reprint Rethinking lipid mediators
    Karsten H Weylandt
    Department of Gastroenterology and Hepatology, Charite University Hospital, Campus Virchow, 13353 Berlin, Germany
    Lancet 366:618-20. 2005
  2. doi request reprint Omega-3 fatty acids and their lipid mediators: towards an understanding of resolvin and protectin formation
    Karsten H Weylandt
    Department of Gastroenterology, Hepatology and Endocrinology, Charite University Medicine, Rudolf Virchow Hospital, Berlin, Germany
    Prostaglandins Other Lipid Mediat 97:73-82. 2012
    ....
  3. pmc Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF-α
    Karsten H Weylandt
    Laboratory for Lipid Medicine and Technology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Carcinogenesis 32:897-903. 2011
    ..The findings also point to a potential anticancer role for the n-3 PUFA-derived lipid mediators 18-HEPE and 17-HDHA, which can downregulate the important proinflammatory and proproliferative factor TNF-α...
  4. ncbi request reprint Colitis-associated colon tumorigenesis is suppressed in transgenic mice rich in endogenous n-3 fatty acids
    Johannes Nowak
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Carcinogenesis 28:1991-5. 2007
    ..These results support a protective role of n-3 PUFA supplementation in the prevention of CRC...
  5. pmc Acetylsalicylic Acid reduces the severity of dextran sodium sulfate-induced colitis and increases the formation of anti-inflammatory lipid mediators
    Thomas Köhnke
    Department of Gastroenterology, Hepatology and Endocrinology, Virchow Hospital, Charite Medical School, Free and Humboldt University of Berlin, 13353 Berlin, Germany Laboratory for Lipid Medicine and Technology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Biomed Res Int 2013:748160. 2013
    ....
  6. pmc Reduction of inflammation and chronic tissue damage by omega-3 fatty acids in fat-1 transgenic mice with pancreatitis
    Karsten H Weylandt
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Biochim Biophys Acta 1782:634-41. 2008
    ..These results suggest a beneficial potential for n-3 PUFA supplementation in acute and particularly chronic pancreatitis...
  7. pmc Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells
    Piet Habbel
    Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States
    World J Gastroenterol 15:1079-84. 2009
    ..To investigate the impact of arachidonic acid (AA) and docosahexaenoic acid (DHA) and their combination on colon cancer cell growth...
  8. doi request reprint Modulation of inflammatory cytokines by omega-3 fatty acids
    Jing X Kang
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Subcell Biochem 49:133-43. 2008
    ..This chapter focuses on the evidence from recent studies using new experimental models...
  9. doi request reprint Omega-6 docosapentaenoic acid-derived resolvins and 17-hydroxydocosahexaenoic acid modulate macrophage function and alleviate experimental colitis
    Cheng Ying Chiu
    Department of Hepatology, Gastroenterology and Endocrinology, Charite University Medicine Berlin, Campus Virchow Klinikum, Berlin, Germany
    Inflamm Res 61:967-76. 2012
    ....
  10. doi request reprint Fat-1 transgenic mice with elevated omega-3 fatty acids are protected from allergic airway responses
    Sueleyman Bilal
    Laboratory for Lipid Medicine and Technology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Biochim Biophys Acta 1812:1164-9. 2011
    ..These results therefore demonstrate a direct protective role for lung n-3 PUFA in allergic airway responses and an increased generation of protectin D1 and resolvin E1 in this context...
  11. ncbi request reprint Omega-3 fatty acids alleviate chemically induced acute hepatitis by suppression of cytokines
    Christoph Schmöcker
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Hepatology 45:864-9. 2007
    ..CONCLUSION: The results of this study offer evidence for an inflammation dampening effect of omega-3 polyunsaturated fatty acids in the context of liver inflammation...
  12. doi request reprint Analysis of omega-3 and omega-6 fatty acid-derived lipid metabolite formation in human and mouse blood samples
    Beate Gomolka
    Department of Medicine, Division Hepatology, Gastroenterology and Endocrinology, Rudolf Virchow Hospital, Charite University Medicine, Berlin, Germany
    Prostaglandins Other Lipid Mediat 94:81-7. 2011
    ..Further studies will now have to evaluate lipid metabolite generation capacity in different physiological and pathophysiological contexts...
  13. pmc Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis
    Christian A Hudert
    Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 103:11276-81. 2006
    ..They add insight into the molecular mechanisms of inflammation protection afforded by n-3 PUFA through formation of resolvins and protectins other than inhibition of n-6 PUFA-derived eicosanoid formation...
  14. ncbi request reprint Lipoxins and resolvins in inflammatory bowel disease
    Karsten H Weylandt
    Department of Medicine, Division of Hepatology and Gastroenterology, Charité Medical School Virchow Hospital, Humboldt University of Berlin, Germany
    Inflamm Bowel Dis 13:797-9. 2007
    ..In this article we discuss the emerging knowledge on the effects of lipoxins and resolvins on various inflammatory pathways and why they are promising candidates for novel therapies of human inflammatory bowel disease...